Salmonella tifimurium - pathogen, isifo, unyango

iintsholongwane salmonella tifimurium yaziwa amayeza Salmonella enterica serovar typhimurium. It is a gram-negative, iintsholongwane intonga-ezimise nge misila (nezakhiwo iinwele-ezifana nemfusa), apho lihamba eziphilayo.

iintsholongwane ogama - oyena nobangela ityhefu ukutya (salmonellosis) ebantwini. Ababenalo ke isikakhulu yehagu, inyama yenkukhu, amaqanda. Izilwanyana nako ayidlulisele.

zihlelwa njani Salmonella?

Ngoko ke, onomdla tifimurium iSalmonella thina - arhente causative yesifo eziyingozi ezinjengezo salmonella. Uhlobo salmonella enterica ubunjwe ohlobo 6:

• enterica;
• salamae;
• arizonae;
• diarizonae;
• houtenae;
• indica.

Enterica zenyathi enterica iquka salmonella ezilandelayo serogroups:

• A (paratyphi A).
• B (kukuku, typhimurium, Agona, Heidelberg).
• C (cholerae cometh, Newport, muenchen, virchowinfantis).
• D (Dublin, enteritidis, rostock, Sendai, typhi).
• E (anatum).

Tifimurium iSalmonella (S. typhimurium)

View enterica ithathwa ngokuba yayintsholongwane eyosulela abantu kunye nezilwanyana kunye neentaka, kodwa okubalulekileyo kakhulu bambalwa kubo abantu. Kunye iimeko ezininzi salmonellosis accounted for S. typhimurium.

Ngeentlobo ezininzi Salmonella ukumelana elwa mihla, ngoko athunyelwa ehlabathini lonke. Ngoko ke, salmonellosis nosocomial - ingxaki enkulu ngelo xesha. Ngowe-80% amatyala yomenzeli causative of nosocomial (nosocomial) salmonellosis - yi S. typhimurium.

izinto phathogenicity

Kwaye kuyingozi unobangela wathi phathogenicity sifo zinto ezilandelayo:

• Misila inika ukuhamba ngokukhawuleza silwanyana.
• Philisi oko ngentsholongwane biyela ziiphagocytes. Kwaye ngenxa ukunganeli phagocytosis okhulayo nokudumba.

• Ukuhlasela umthondo osemqoka kwenza ukuba kungabi-simahla inyama anzongonzongo-elele.
• Ngenxa adhesion ezilungileyo (isihlomelo), ukunika fibrils, pectins, LP-saccharide complex, igciwane lugciniwe emzimbeni.
• Exotoxins (iimveliso yomsebenzi wayo), ukwakha sorhudo kunye emzimbeni elandelayo, permeability rapid nemithambo.
• Endotoxin lula xa usithelekisa phagocytosis yingozi. It ezintsonkothileyo lipopolysaccharide yakha ukunxila. Zegazi, udibaniso e emithanjeni ezincinane kukhokelela nangokurhala, apho DIC. A secretion of Na kunye Cl kunciphisa kwezihlunu gingxi kunye nokwanda motility emathunjini.

Njani ukumelana ntsholongwane?

Salmonella tifimurium abe ukumelana imiba eyahlukeneyo yokusingqongileyo:

1. Kwiinyanga ezintathu zigcinwa izinto ezinxulumene lobushushu igumbi.
2. iminyaka emine zigcinwe ilindle eyomileyo yezilwanyana.
3. iinyanga ezintlanu - emanzini, isiqingatha sonyaka - Iimveliso zobisi kunye inyama, xa amakhoba amaqanda - inyanga.
4. Ukufa kwenzeka kuphela kwi-100 ° C. Iimveliso inyama yokunganyangeki eliphezulu uyanda lobushushu (a iponti inyama kufuneka iphekiweyo iiyure ezimbini, kodwa ke ngoko kukhuselekile). Ngoncedo yityuwa kunye nokutshaya musa ukumbulala salmonella.
5. Le pathogen ungakwazi ukumelana lobushushu ukuhla ukuya -80 ° C.
6. Kuyinto ukumelana ukukhanya UV.
7. Le ntsholongwane kufuneka ukumelana imizuzu engama-20 ukuya ukubulala iintsholongwane.

Uqhambuko lweziganeko salmonellosis waphawula ehlotyeni, sivame ukuxilongwa kubantwana abaselula ngenxa nokungafezeki amajoni emizimba yabo.

Pathology ayihambi yi alimentary kwakhona ukuqhagamshelana kunye zoqhagamshelwano-khaya. Hi ndlela leyi, kubalulekile ekusebenziseni amaqanda kukuba ukuhlawula ingqalelo uhlobo protein kunye sac. Xa turbidity, legazi, ivumba ebolileyo, iqanda kungenzeka sifo. Kufuneka zilahlwe, izitya kugalela ngezandla chlorine njengoko ezisingathwa. Isepha kwezi meko swi nga pfuna.

flash Winter, yokufa kunye nendlela transmission qhagamshelana-indlu amelana nemithi zenzeka izizathu kwaye ngenxa yokuba ukhuseleko lokutya into enye.

okuthatha

Ithuba elisuke ithatha iiyure ezintandathu ukuya kwezisibhozo ngosuku, kodwa ngakumbi iimpawu yokuqala ukuvela phakathi kosuku lokuqala okanye ezimbini emva kokutya imveliso angcolile.

Kuphula emzimbeni ngamanzi netyuwa ngenxa urhudo, isitulo uba anzongonzongo, amagwebu, ezinukayo, nemifuno, sifunda i "nomgxobhozo udaka" kunye kumaza izihlandlo elishumi ngosuku, iveki okanye ngaphezulu.

Isifo siqala wayibona, luphawulwa ubuthathaka, silale, iintlungu ezolileyo esiswini (epigastric kunye umbilicus). Umnqe kabuhlungu Ngokucofa, ngokuxokozela oluvakalayo kunye nokudumba ngokuphawulekayo.

Salmonella tifimurium - Laboratory Uxilongo

Xa kufunyaniswa isifo abachatshazelwa yi parameters zilandelayo:

• Linyuke neentlenge erythrocyte;
• leukocytes kunye shift ukuya ekhohlo;

Lwegciwane Sithole kwiincindi zebhayoloji (endleni, igazi, umchamo, iziko abachaphazelekayo) kunye neemveliso nokusola indlela bacteriological. Isiphumo sokugqibela kukuthi, njengokuba umthetho, elungiswe ngomhla wesihlanu.

Phezu ukungenwa Salmonella tifimurium, ezi mpawu zilandelayo:

• umkhuhlane;
• Ukugodola;
• sorhudo kakhulu;
• ukubuyisa.

unyango

Esi sifo kuba siyabulala ebuntwaneni, abadala, kwaye izigulane kunye nokuphungulwa nezifo. Kwaye lo iSalmonella tifimurium yingozi.

Unyango kukuba kusetyenziswa elwa emzimbeni. Kwakhona amisele antispasmodics, amalungiselelo enzyme, sorbents, antidiarrheals. "Table №4» ibonisa yokudla.

Therapy kufuneka ibanjwe phantsi kweliso elibukhali likagqirha engqongqo, kunye namanyathelo resuscitative ezisetyenziswa kwiimeko ezinzima. Of sorbents ngokuba ezigulela umzimba kuyacetyiswa ukuba usebenzise iziyobisi zilandelayo:

• "Enterosgel";
• "Liferana";
• yasebenza carbon;
• "Smecta";
• "Enterodeza".

Nge ukugabha rhoqo gqolo ukuba inyanzelekile ukuba ubize inqwelo yezigulana ukuze aphephe ukomisa. Isigulane sidla emiselweyo "Regidron". lobushushu Ukwanda kunciphisa antipyretics.

Active nxamnye salmonella salmonella antibiotics enterica

arhente Antibacterial asebenzayo ngokuchasene salmonella salmonella enterica, enze "furazolidone" "ciprofloxacin", "Rifaximin", "nifuroxazide". Kodwa angakunika kuphela gqirha, ukuchola idosi ngamnye kuthathelwa ingqalelo imeko yomguli, abanentsholongwane salmonella tifimurium.