Analogs kunye nemiyalelo yokusebenzisa "lomefloxacin"

Yintoni indawo ezifana ichiza njenge 'lomefloxacin'? Analogs beziyobisi, injongo yaso, kunye nezithintelo yokusetyenziswa elapha kuxoxwa ngezantsi. Uza kufunda kwakhona malunga nendlela yokusebenzisa kakuhle esi sixhobo, kwaye yintoni umthamo.

Isiyobisi, ukupakishwa zayo, nezibilini zayo licandelo

Yeyiphi iphakheji kunokufumaneka khona imali? Apho kunika umyalelo kwi isicelo? "Lomefloxacin" - unabo, zibekwe kwi kumadyunguza kunye zahlanganiswa Imiqulu ephepheni, kunye nesishwankathelo.

Zeziphi iquka izithako ichiza? Eyona nto elikhutheleyo ichiza lomefloxacin hydrochloride. Kwakhona oku kuquka ezinye amacandelo abancedisayo.

Iimpawu zonyango lwe ichiza

Yintoni iipilisi 'lomefloxacin'? Manual ukuba olu nyango elwa bactericidal ukuba fanele imali iqela antibiotikopodobnyh ukuba, oko kukuthi, fluoroquinolones, yaye imele isizukulwana sesibini kula machiza.

Yintoni ebangela ukusebenza elwa beziyobisi phantsi ingqalelo? Ezinjalo iipropati "lomefloxacin" Amacwecwe (400 mg) ifunyenwe ngenxa yokuba ubutyebi babo esebenzayo iyakwazi nempembelelo uvimba kwi DNA gyrase (ngamanye transcriptase bacteria) enika supercoiling. Ngapha koko, le arhente uyila compound zizinze (isakhiwo) kunye tetramer yayo kuphazamisa DNA umbhalo kanye phindana iiseli yintsholongwane, ibangela intshabalalo yabo elandelayo.

Umsebenzi evakaliswe nguloo medicament ivela iintsholongwane aerobic ezimbi kakhulu ezifana gonococci, Salmonella, Pseudomonas, Haemophilus influenzae kunye Escherichia coli, ikholera pathogen, meningococci, Shigella, Morganella njalo njalo. Kwakhona "lomefloxacin" medicament (400 mg) xi ukusebenza kwi Proteus, chlamydia, Campylobacter, mycoplasma, legionella, ezinye pneumococci kunye staphylococci.

Asinako ukuba ichiza wathi kuphumelela kakhulu nxamnye Mycobacterium tuberculosis. Uyakwazi ukunciphisa ixesha ukususwa yabo, kwakunye resorption yokuqala lingene ezikhoyo.

Zonyango ukusebenza "lomefloxacin" ngisho kwi zoqhaphelo esezantsi egazini. Ukuba le uxhathiso nto yabonakala kunqabile kakhulu.

Amandla entshukumo iipilisi amayeza

Ugxile uthe medicament? Oko ikuthethayo ngalo imiyalelo ukusetyenziswa? "Lomefloxacin" liye absorbency elungileyo. Emva kokufumana amayeza ayo xi peak plasma afunyenwe kwisithuba semizuzu 55-85.

I protein plasma enebana ichiza kuphela kwi-10%. Kwakhona, iye iimpawu zalo ezilungileyo ukufakwa kwizigqeba ezahlukeneyo kunye namalaphu (kubandakanywa zangasese, amalunga, iindlela nokuphefumla, amalungu ENT, amalungu zangasese, amathambo, isisu, iithishu ezithambileyo, njalo-njalo), apho umxholo walo amaxesha 5-7 ngaphezulu plasma.

Kufuneka kuqatshelwe ukuba ezinye lomefloxacin umzimba kwaye yenza nezakhi eziliqela.

Isithuba kukhuthaza ichiza ziyure ezili-9. Isiphumo ngayo nge secretion tubular Umchamo (70-85%) kunye endleni (25-30%).

Ubungqina obubonakalayo buxela ukuba nesikhundla indlela

Bambalwa abantu bazi, kodwa kwikhemesti ndisezintanjeni zingafunyanwa nje ipilisi nje "lomefloxacin", kodwa iziyobisi "lomefloksatsin + pyrazinamide + ethambutol + Prothionamide + Pyridoxine". Kule meko zombini medicament Kuthiwa eboniswe zisetyenziswe:

• usulelo (ubovu) isikhumba kunye kwizihlunu ezithambileyo (kubandakanywa ukutsha, amanxeba sifo, njl);
• osteomyelitis;
• chlamydia kunye ukuvuza ngaphantsi (kubandakanywa i-Blepharoconjunctivitis kunye conjunctivitis lwechlamydial);
• womchamo zesisu (umz, kholera, segazi, yicesina, salmonellosis);
• izifo ezihlasela zosulele ngokuphefumla (kuquka kwemigudu yomoya, uhlobo nezolo);
• womchamo biliary;
• izifo kule ndawo enzala (umz, urethritis, prostatitis, Ngokuzimela, pyelonephritis);
• nesifo sephepha yemiphunga (kuquka unyango kwabantu inkqubela ngokukhawuleza iintlobo zesi sifo, kwakunye nokwanda yokumelana 'isoniazid "yaye" rifampicin "kunye ukuxhathisa ichemotherapy);
• phambi nasemva kotyando transurethral (kuphela iinjongo umbala).

Siphelisa ukuqeshwa amacwecwe elwa

Kwezinye iimeko, awukwazi ukusebenzisa ichiza phantsi ingqalelo? Yintoni le usixelela yesikhokelo? "Lomefloxacin" sele contraindicated ukuze zisetyenziswe:

• yokumitha;
• lwebele;
• ubuntununtunu lobuqu lwamachiza ngoweqela fluoroquinolone;
• njengabantwa (mhlawumbi inhibition lophuhliso skeletal).

Imiyalelo yokusebenzisa

"Lomefloxacin" - iipilisi ebonisiweyo kuphela yokufakwa. Kufuneka zithatyathwe kanye ngosuku, kungakhathaliseki ukuba ukutya, ukusela malunga 230 ml yamanzi zesiqhelo.

Ubude unyango kunye eli yeza kuxhomekeke uxilongo, kwakunye ebukhulwini sifo yaye indlela yobuntununtunu lwe gciwane.

Ayinzima etsolo kwemigudu kunye bronchopneumonia flow aphathwe umthamo 400 mg beziyobisi iintsuku ezilishumi.

Xa unyango lwe chlamydia (enzala), kubandakanywa kwezifo kunye lwechlamydial, gonococcal kunye lwechlamydial, izigulane elawulwa 400-600 mg kweziyobisi ngamnye ngosuku, kunye ngethuba isicelo iintsuku ezingama-28.

Unyango likakade nzima yinyumoniya kunye nohlobo kwemigudu yomoya lokhu e idosi yemihla ngemihla elingana 400-800 mg kweziyobisi, iiveki ezimbini.

Xa isifo mycoplasma ingqalelo iziyobisi emiselweyo 400-800 mg ngosuku, kunye ngethuba lolawulo amacwecwe kwiiveki ezi-3.

womchamo izifo ezosulelayo efanele kuthomalaliso 400 mg beziyobisi. Nale unyango kwamatyala gingxi ukwenziwa iintsuku ezi-5, kunye nezintsonkothileyo - iintsuku ezili-14.

In: ukuvuza ngaphantsi etsolo iziyobisi "lomefloxacin" ekucetyiswa ukuba athathe idosi ka 600 mg. Ke ukuba uhlobo ezingapheliyo zesi sifo, unyango yayo yenziwa ngaxeshanye kunye immunotherapy ethile. Kulo mzekelo, uthathe amayeza kwi idosi enye yemihla ngemihla iintsuku ezi-5.

Unyango lwesifo sephepha yemiphunga kungathatha iintsuku 14-30 (kwezinye iimeko ukuya kwiinyanga ezi-3). sifo ukuphatha ithamo lwemithi mg 200 kabini ngemini.

Xa wavakalisa ezimbi kwezintso okanye indalo ngcathu, kwakunye nabantu ihaemodialysis, "lomefloxacin" ziqhutywa isixa 400 mg ngosuku, nokuncipha yayo ngakumbi mg 200.

Lo mkhuba umlinganiswa elibi

Yiyiphi imiphumo emibi kunokubangela iipilisi 'lomefloxacin "? Khokela yalatha abasabela ilandelayo:

• bronchoconstriction, ukwanda yencindi secretion, isicaphucaphu, ukukhohlela, dysphagia;
• dyspnea, ukugabha, izifo nokuphefumla, isifo sorhudo, goiter;
• iimpawu ezifana nomkhuhlane, dysgeusia, iintlungu epigastric, ukuqumba;
• Ukuphakamisa enzyme zesibindi, kome emlonyeni, ukopha zesisu;
• kwesisu, arthralgia, amahlaba ithole, ukutshintsha ulwimi umbala, myalgia;
• pseudomembranous besisu, intloko ebuhlungu, utshintsho ukutya, vasculitis, isiyezi;
• ubuthongo, isisa webele umva, ukudinwa, uvalo, uvakalelo oluthile jikelele, ukudakumba, Barr;
• hyperkinesia, ukudinwa, unditsho, ukuba nemibono;
• intlungu emehlweni, ingxolo, kunye neentlungu ezindlebeni;
• dysuria, ukwanda inkanuko, hematuria, paresthesias;
• crystalluria, ukungaboni;
• albuminuria, glomerulonephritis, Leucorrhœa, nokudumba, polyuria, epididymitis, ubunzima uchama, orchitis, tenesmus;
• cyanosis, anuria, hypotension, හසුරුව isiphathi, tachycardia, arrythmia, iintlungu isizalo, bradycardia;
• ukopha intermenstrual, thrombocytopenia, candidiasis lobufazi, iposi engabalulekanga, cardiomyopathy, phlebitis;
• ukuqhubela phambili sisifo sentliziyo kunye angina, purpura, ukuphazamiseka cerebrovascular, ukurhawuzelela kwesikhumba;
• Embolism yemiphunga, photosensitivity, ukwandisa fibrinolysis, irhashalala, lymphadenopathy, irhashalala;
• epistaxis, erythema (yingozi), eziva Ukugodola, sifo, komzimba;
• superinfection, hypoglycemia, Candida, kuyabuya lunxano.

An libanda, iipilisi

Ngenxa libanda, iipilisi "lomefloxacin" izigulane zifumana isicaphucaphu, izilonda ilunga le isifo zesisu, kululwa ye QT-xesha, isiyezi, ukuxhuzula, ukudideka, kwakunye ngayo ezibi ukwanda.

Ngenxa ihaemodialysis libanda kuthetha ingqalelo unyango angasebenzi ngaphezu iimeko lwenziwa ngokwesiseko iimpawu ezikhoyo.

Intsebenziswano kunye namanye amachiza

Kunye indibanisela 'lomefloxacin "ne" theophylline "yokucolwa yakhe phantse ukuncokola.

Xa ulawulo ngaxeshanye ye asidi kunye sucralfate akhiwa izakhiwo chelate ezinciphisa bioavailability of lomefloxacin. Kungenxa yoko le nto lekhefu phakathi ulwamkelo uthe imithi kufuneka iiyure ezingama-4.

ukusetyenziswa Joint of "lomefloxacin" kunye ngeedosi eziphezulu caffeine lwenze isiqingatha ebomini yokugqibela.

Xa unyango lwesifo sephepha akufuneki kuqhutywa ngaxeshanye kunye ulwamkelo mali "rifampicin", kungenjalo kuya kukhokelela amanyathelo awunandaba.

unyango ngaxeshanye kunye NSAIDs kwandisa ubungozi kweziyobisi kwaye kungenza ukuxhuzula.

"Lomefloxacin" nako ukwandisa ngobuchule anticoagulants lolawulo ngomlomo.

Zemithi, ezo blocker of secretion tubular, zinqanda kukhuthaza "lomefloxacin".

izincomo ezithile

Ukuba isifo sezintso kufuna uhlengahlengiso olusisinyanzelo umthamo, leyo ixhomekeke metric QC.

Zonke unyango kufuneka ayeke kwimpembelelo elide nayiphi na imithombo UV ukukhanya, kuquka kwelanga.

agents Vitamin ziquka ongeziweyo ezahlukeneyo izimbiwa kufuneka uthathe 120 imizuzu emva okanye phambi kokuba iipilisi abafumana ingqalelo.

amachiza afanayo

Medicament "lomefloxacin" iye nucleoside ezininzi. The main amachiza ababambeleyo iingcali ingqalelo ezi zinto zilandelayo: "Abaktal", "Elefloks", "Zanotsin", "TSifran", "Avelox", "Tsiprolet", "Zofloks", "tsiprinol", "Kvintor" "ciprofloxacin", "Levofloxacin "" tarivid "," Levotek "," pefloksatsina "," Levofloks "," Ofloxacin "," Norbaktin "," Ofloks "," norfloxacin ".

Tablets "lomefloxacin": ncomo

Xa ngokucacileyo arhente esosulelayo nokutshuntsha kwisizukulwana yesibini fluoroquinolones, kwakunye ukhetho oluchanekileyo amathamo zamachiza kunye nonyango elide, ukubuyekeza iindlela ezikhoyo kusendleleni HIV.

Ngokutsho izitetimenti izigulane, eli chiza izibonakalise njengolona an unyango olusebenzayo elwa ejongene ngokwaneleyo iintsholongwane ezahlukeneyo zophendlo lwezifo. Noko ke, abanye abasebenzisi zithi ukuba eli chiza maxa wambi kubangela uphuhliso yeziphumo ebezingalindelekanga ethile, kodwa umgaqo bayagula-ezichazwe kwindalo, okanye ngokwabo ngokukhawuleza emva kokuphela unyango.