Bucala 'Azafen', imiyalelo ukusetyenziswa, imiphumela emibi

Drug "Azafen" libhekisela kwiqela le yokunciphisa tricyclic. Kuye sine ephakamileyo, anxiolytic kunye neziphumo antiaggressive. Eli chiza isetyenziswa ngokubanzi yonyango wemiphunga misinga lesibini, ezifana:

- iqala;

- astenodepressiya;

- zangaphandle;

- utshwala;

- mkhosi;

- karhulumente ngexesha iimeko somatic ezikumila ezigulo ezondeleyo.

Eyona nto elikhutheleyo "Azafen" inkcazelo iziyobisi libhekisela pipofezine. Indlela yesenzo kwento ngokusekelwe inhibition loku kwamkelwa neuronal of norepinephrine kunye serotonin. Oku kukhokelela ekwandeni uyondelelwano lwee- pipofezine kwi-CNS kunye neempawu depressive isikiwe.

Kukho enye inzuzo EC efanayo imiyalelo "Azafen" bucala action kweziyobisi zokusetyenziswa ibhekisa ukungabikho neziphumo zaso cardiotoxic. Ziphawuleka njenge nempembelelo entle lithetha "Azafen" kwi ukuphazamiseka ngokwenene, isenza buthathaka ukuphazamiseka lo somatic, izangoma kunye yawo ezinxulumene noxinzelelo. ukusebenza High "Azafen" yemiyalezo uchaza nxamnye asthenia, iingxaki ezivele ngenxa psyche yabantu somatic. Ngexesha lolawulo beziyobisi izigulane liyalahleka ixhala, ntshikilelo. dynamics ezincumisayo kwizifundo izigulane anorexia nervosa, ulale kwesiqhelo nobuthongo shwaka emini.

Medicine "Azafen", ngokusekelwe kwiipropati zabo pharmacokinetic iye digestibility elungileyo, oko ako kakuhle ngokusebenzisa wokugaya, uye bioavailability ephakamileyo (80%), xi igazi iphezulu ifikelela sele kwisithuba iiyure ezi-2. Esibindini kwenzeka biotransformation pipofezine ukuba engasebenziyo metabolites ukuba zixhonyiwe nezintso. ukukhululwa elipheleleyo ichiza kumzimba kwenzeka kwisithuba seeyure ezingama-16.

Unyango kukudakumba of imvelaphi ezahlukeneyo kubonisa olulandeleyo ukusetyenziswa manual "Azafen" umyalelo kweziyobisi ikhankanya urhulumente, edwelisa zonke iintlobo depressioy, ekucaca ukuba iziyobisi.

Kukho Izimo eziliqela ngokufumana "Azafen" imiyalelo yeQela zokusetyenziswa ukubonisa lithi zilandelayo azikho ehambisana unyango ngamachiza:

- diabetes;

- ukwabelana Mao inhibitor ;

- iposi engabalulekanga, ukusilela intliziyo, kwemithambo;

- hepatic okanye ukusilela kwezintso;

- sisifo esosulelayo, kakhulu;

- karhulumente emva yingozi cerebrovascular (stroke);

- Pregnancy, zisanyisa.

Oko kufuneka umntu alumkele kukuvela iziphumo ebezingalindelekanga kunokwenzeka ngexesha unyango, ukuba ahleliweyo isiyezi kunye intloko ebuhlungu, negazi, ukugabha kunye isicaphucaphu. Ngelishwa, akukho lwazi malunga nonyango xa libanda, iziyobisi, kwiimeko ezinjalo, kuthatha nomqondiso. Kumba Izimo kufuneka zongezwe ingxaki efanayo "Azafen" kunye notywala. Ezi mabinzana mabini ngokupheleleyo ahlobene ngexesha unyango kufuneka ayekiswe ukusela utywala kunye yolwamkelo ngaxeshanye kumalungiselelo equlethe ethanol.

I 'azafen "ayifumanekanga iipropati anticholinergic, ngoko musa ukunikezela unyango ngamachiza kwizigulane glaucoma kunye. asihambisani koko nge utywala, kukho umngcipheko isicelo ngaxeshanye beziyobisi kunye anticoagulants, antihistamines zonke iziyobisi, CNS depressants. Nceda uqaphele ukuba ukwamkelwa ngaxeshanye "azafen" ngeziyobisi antiepileptic ukunciphisa ifuthe yokugqibela.

Released "Azafen" ngokutsho ngqo yeresiphi, ithuba lokugcinwa obukhulu iminyaka emi-5, kufuneka igcinwe kwi tmax 25.