Chloramphenicol (ekhompyutheni) - yemiyalezo

Isishwankathelo kulungiselelwa chloramphenicol ifomu umthamo - amacwecwe, amacwecwe wawutyabeka okanye njengezingxobo.

isakhiwo

into esisebenzayo:

• chloramphenicol - 250/500 mg (1 tablet)

Excipients:

• calcium stearate;
• Potato starch.

Isenzo amayeza le chloramphenicol iziyobisi

Amacwecwe Chloramphenicol abantu abanzi-spectrum nemithi, nto leyo olusebenzayo ngokuchasene nobuninzi zombini gram-HIV kunye gram-elibi iintsholongwane. Ngaphezu koko, iziyobisi esebenzayo ukuze enze ezimelene leyo abanganyangekiyo nemithi zilandelayo - penicillin, sulfonamides, streptomycin.

Ichiza wenza phezu silwanyana, ukuphazamisa kuyondelelaniswe yayo protein, ngaloo ndlela ngeedosi ngamayeza nokunyanga, eli chiza zisenokusongamela inyathelo bacteriostatic.

Kwinkcaso beziyobisi microorganisms kade, yaye ngaloo ndlela wenza umnqamlezo-ezixhathisayo kwezinye nemithi isakhiwo efanayo.

ukulungiselela Iimpawu chloramphenicol

Amacwecwe ichiza elisetyenziswa eziliqela zizifo ezinokubangelwa igciwane:

• paratyphoid;
• esifo;
• salmonellosis;
• shigellosis;
• lweBrucellosis;
• isifo rickettsial;
• tularemia.

imiphumela emibi chloramphenicol iziyobisi

Xa Ityhefu iziyobisi, okanye ukuba ngaba hypersensitive inokuba neziphumo ebezingalindelekanga, ezinxulumene iinkqubo ezahlukeneyo umzimba.

iziphumo ebezingalindelekanga ezinxulumene igazi:

• thrombocytopenia;
• leukopenia;
• reticulocytopenia;
• ukunciphisa inani haemoglobin egazini;
• igazi aplastic.

Imiphumela wabaxelela zesisu iphecana kunye yangaphakathi ingaphandle:

• ukuphalaza;
• isicaphucaphu;
• ukuqumba;
• sorhudo;
• esicaphukisayo mucosal;
• stomatitis;
• glossitis;
• goiter;
• ukwenzeka ezinzwaneni.

iziphumo ebezingalindelekanga ezinxulumene nenkqubo luvo:

• ubuthulu (ingathityazwa);
• ukuba nemibono;
• neuritis optic;
• neuritis neuropathy;
• Encephalopathy;
• ukudana;
• ebuhlungu.

iziphumo ebezingalindelekanga ezinxulumene negazi lakho:

• umkhuhlane;
• ufunga kwesikhumba;
• anaphylaxis;
• Angioedema.

Izimo ukusetyenziswa yokulungiselela chloramphenicol

Amacwecwe ichiza akukhuthazwa kwimeko ukuba isigulana umntu omnye okanye ngaphezulu kule miqathango ilandelayo (uthi):

• izifo egazini, kuquka inhibition igazi;
• ukhwekhwe;
• izifo fungal kwesikhumba;
• onokhwekhwe;
• umsebenzi isibindi othile;
• ari;
• Ukukhulelwa ne zisanyisa;
• porphyria;
• yobudala ukuya kwiminyaka emi-3.

libanda, iziyobisi

Kwimeko libanda, ukuba ichiza kusetyenziswa chloramphenicol, sinokufumana mpawu zilandelayo - iingxaki amalungu hematopoietic kunye neenkqubo, apho zidla ezinxulumene nokusetyenziswa elide amathamo ezinkulu kakhulu lweziyobisi olunokubakho. Iingxaki zenzeka umqala obuhlungu, isikhumba pallor, ukopha, umkhuhlane kunye ubuthathaka jikelele umzimba.

Xa abantwana, i libanda singabonakala:

• ukuphalaza;
• ukuqumba;
• ngebala ndiyingwevu;
• ukuphefumla arrhythmic;
• emzimbeni;
• ekuweni sentliziyo.

Ukuze ukuphelisa ezi mpawu, kufuneka ngoko nangoko emva kokuba iimpawu zazo bayayeka ukuthatha amayeza, ahlambe isisu, aqale abafumana sorbents kwaye uqale unyango kwangumqondiso njengoko kuyimfuneko.

Drug intsebenziswano chloramphenicol kweziyobisi

Amacwecwe akufanele kuthathwe xa kunokwenzeka ukuba umntu onikwe ukuba ichiza ezilawulayo ukuyilwa egazini, kwaye ingakumbi izixhobo ezifana cytostatics, pyrazolone avela kunye sulfonamides, ngokungathi ifuna ningabaniki ithuba, ngoko kuyimfuneko ukuba ongendawo amgibe nokusetyenziswa chloramphenicol bayifumane enye.

Iziyobisi ezifana phenobarbital, rifampin, rifabutin kwaye kakhulu ukunciphisa ukufumaneka kunye nokusebenza chloramphenicol.

Ichiza kunciphisa isiphumo antibacterial of penicillins kunye cephalosporins. Ngapha koko, oku kunciphisa ukusebenza erythromycin, lincomycin, kunye clindamycin, kunye.