I-Lamotrigine: izifaniso, imiyalelo yokusetyenziswa, izibonakaliso, ukuphononongwa

Ukuhluthwa kwesinye isinye sezifo eziqhelekileyo zesimiso senzwa. Ukubonakaliswa kwayo okuphambili kwithuba elifutshane eliqhelekileyo lenzekile. Ukufa kwesifo kutholakala namhlanje kumntu wonke umntu ekhulwini. Kwaye ke, iinkampani ze-pharmacological zivelisa amayeza amaninzi ajoliswe kunyango lwesi sifo. Esinye isilwanyana esinjalo nguLamotrigine. Iingxoxo zeli gama zingabiza ixabiso elibi okanye elithengiweyo, zinezinto ezifanayo ezisebenzayo okanye enye ekubunjweni.

Ukukhutshwa kwefom nokubunjwa kweyeza

Isilwanyana "uLamotrigine" ("Lamictal") sinikezelwa kumayeza eepilisi. Enye ipakethe ingaqukatha iziqwenga ezili-10 okanye ezingama-30. Ngamanye amaxesha kuthengiswa ukuba kunokwenzeka ukuhlangabezana nale malungiselelo kunye nefowder. I-substance ebonakalayo esebenzayo kweli liyeza yi-lamotrigine.

Kwakhona ukwakhiwa kweyeza kufaka izinto ezinjengalezi:

• I-anhydrous silicon dioxide;
• I-Magnesium stearate;
• Povidone;
• Lactose monohydrate;
• MCC;
• Isitrodium carboxymethyl isitashi.

I-Lamotrigine: efana nexabiso elincinci

Iindleko zeliyeza kwiifommitha malunga nee-ruble ezingama-600-700 zeplatethi ezingama-30. Oku kunjalo, kubiza kakhulu. Ngoko ke, ezininzi izigulane zisebenzisa endaweni yolu cwangciso.

Ngokomzekelo, unokusetyenziswa endaweni yezilwanyana "IiLamotrigine" ezifanayo:

• Topiramate.
• "Seizar".
• "Levetiracetam."

I-Topiramat yeyeza

Esi sidakamizwa sithunyelwa kwiimarike ngokuqhelekileyo kwifom yefowuni. Amacwecwe angama-30 ale mveliso kuxhomekeke kumthengisi unokuhlawula i-ruble 200-400. Kwezinye iiprosemesi le mveliso idayiswa ngama-ruble ayi-150-160. Into ephambili ebonakalayo kweli gama liphezulu. Ubungqina bakhe bufana ne "Lamotrigine."

Ukulungiselela "Seizar"

Eli liyeza lithengisa kwii-pharmacy ukusuka kuma-ruble ama-250 ukuya kuma-500. Kodwa kwezinye iidolophu "i-Seizar" ithengiswa kwintengo ephezulu kune "Lamotrigine". Izigulane ezifuna ukuthenga isiza esincinci, kufuneka zibuze malunga neendleko zayo kwii-pharmacy eziliqela.

Inkunkuma ephambili yeli gciwane yi-lamotrigine. Oko kunjalo, esi sixhobo sibhekisela kwiimpawu ezifanayo "zeLamotrigine."

Isiza "Levetiracetam"

Esi sidakamizwa sithengiswa ngexabiso lama-ruble angama-300-500 ngamapilisi angama-30. Isithako esisebenzayo esisisiseko yi-levetiracetam. Njengazo zonke iimpawu ezikhankanywe ngasentla, eli liyeza lisetyenziselwa iqela lezilwanyana zokulwa ne-antiepileptic.

Indlela amayeza asebenza ngayo emzimbeni wesigulane

Ngoko, ziphi iimpawu zesilwanyana "iLamotrigine", sifunde. Ukuqhubela phambili siya kuqwalasela ngokuchanekileyo oko, ngokwenene, eli liyeza kunye nendlela ekufuneka ithathwe ngayo.

Okokuqala, masiqhelane naluphi uhlobo lweyeza elithi "Lamotrigine" indlela yokusebenza. Ukungena emzimbeni wesigulane, into esebenzayo yale nkunkuma igxininisa imimbrane ye-neuronal kwaye igxotha ukukhululwa kwe-pathological acid ye-glutamic (ngenxa yokugqithisa okungaphezulu kwayo, eqinisweni, ukutshatyalaliswa kwe-stroke episode).

Phakathi kweempawu zale chiza, phakathi kwezinye izinto, unokuzichaza ezi ngongoma ezilandelayo:

• Isantya sesenzo siphuthuma ngesisu esipheleleyo, ukuphumelela kwesenzo sokutya, nangona kunjalo, akanalo niphumo elibi;
• Ukuphuza isilwanyana ngokukhawuleza kwaye ngokuthe ngqo kwi-digestive tract;
• Into esebenzayo yokulungiselela ijikeleza ngeempahla kwifomu ehlobene neprotheni.

Isilwanyana "i-Lamotrigine" isetyenziswe kwisibindi. Kuxutywe kule ngxaki ikakhulukazi kunye neentso. Yingakho izigulane ezinengxaki ngalezi zitho, iziza kufuneka zilawulwe ngokucophelela.

Iimpawu zokusetyenziswa

Iyintoni injongo ye "lamotrigine"? Oogqirha banquma ukuba le nkunkuma ifumaneke xa:

• Ukuxhatshazwa ngokukhethekileyo kunye nokubanzi;
• I-Monotherapy yokungafi.

Kwakhona, iipilisi ze "Lamotrigine" ngamanye amaxesha zingasetyenziselwa ukukhusela ingxaki yokukhathazeka kwemizwelo. Ezi zibandakanya, umzekelo, ukuxinezeleka, ukuphazamiseka kwengqondo okanye ukukhathazeka ngengxaki, njl. Oko kukuthi, eneneni, iyeza lingafumaneka, phakathi kwezinye izinto, kwiqela leengqondo ze-psychotropic. Kwaye oku kuthetha ukuba kufuneka kuthathwe ngokucophelela.

Ziziphi iingqinisiso?

Ukuze ubhale le ngonyango efanelekileyo, ngelishwa, ayikwazi ukuba zonke izigulane. Ukungqinelana kweziyobisi "uLamotrigine" unalandelayo:

• Ukuhlonipha kunoma yiyiphi inxalenye yesilwayo;
• Ukukhulelwa kunye nokulahlwa.

Awukwazi ukumisela le nkunkuma kubantwana abangaphantsi kweminyaka emi-2. Abafazi abakhulelweyo nabaqhawulayo, le nkunkuma ayinqunywanga ngokuyinhloko kuba umphumo waloo mzimbeni awuzange ufundwe ngokupheleleyo.

I-Lamotrigine: imiyalelo yokusetyenziswa

Umthamo weli zizabisi ukhethwe isigulane ngugqirha ngabanye. Abantu abadala banama-25 ukuya kuma-200 mg ale mayeza. Thatha le pilisi ugqirha izigulane kabini ngosuku. Umthamo omkhulu wemihla ngemihla yeLamotrigine ngu-700 mg. Qalisa ukufumana imali ngokuqhelekileyo ngeqondo elincinci. Ukongezelela, isixa semveliso esetyenzisiweyo sanda ngokunyuka.

Kubantwana abaneminyaka emi-2 ukuya kwe-12 ubudala, eli liyeza linokumiselwa oogqirha kwi-2-15 mg / kg ngosuku. Izigulana ezincinci ezinokuhluthwa kufuneka zithathe le myeza kabini ngosuku. Umthamo wemihla ngemihla yezigulane i-400 mg.

Imiyalelo ekhethekileyo

Nanku umyalelo wokusetyenziswa kweLamotrigine. Nangona kunjalo, xa kuchazwe izigulane, oogqirha kufuneka baqwalasele nangemigaqo ekhethekileyo.

Ngokungafani nezinye iziganeko zayo, isilwanyana "uLamotrigine" sinokumiselwa kwizigulane, njengoko sele zikhankanywe ngaphambili, ngokuhluleka kwesibindi. Nangona kunjalo, kulo mba ugqirha kufuneka agcine isigulane ngokucopheleleyo. Imilinganiselo yesilonda ngokwayo kufuneka iyancitshiswe malunga nama-50-75%, kuxhomekeke kubukhulu bomonakalo wesibindi.

Akunakwenzeka ukuqeda lesi sigulo ngokugqithiseleyo kwizigulane zaliphi na iqela leminyaka. Oku kunokubangela ukuba ihluthe i-static status. Ukurhoxiswa kwesi siza kuhamba kakuhle, kunciphise umthamo kwiiveki ezimbini.

"I-Lamotrigine" kunye notywala azinxulumani nezinto. Ukusela utywala ngelixa lonyango le nkunkuma ayikwazi. Utywala bunokuphucula kakhulu umphumo wale nkunkuma, elinezinye iimeko ezinokuba yingozi. Isigulana sinokubonisa ngokulula iimpawu zokugqithisa.

Ziziphi iziphumo ezichaphazelekayo ezibangelwa ngamachiza

Kakade, thabatha isilwanyana "uLamotrigine" kufuneka imiselwe kuphela ugqirha. Inyani kukuba le mayeza angabangela ezininzi iziphumo ezibi, ngamanye amaxesha nokuba yingozi kakhulu kwimpilo nobomi bomguli. Umzekelo, emva kokuthatha i-Lamotrigine, izigulane zinokuhlangabezana nale ngxaki:

• Ukhathala okwandisiweyo kunye nentloko;
• Ukuxhatshazwa okanye ukuxhalaba;
• Rash;
• Ukudideka;
• Umbono ogqityiweyo;
• Ukuphazamiseka kwezixhobo zokusebenza;
• Isihlunu, ukuhlanza.

Kwangenzeka ukuba kwizigulane ezinokuhluthwa nokuphazamiseka kweso siza.

Rash kwizigulane

Yiyo yempembelelo ecaleni eyenza izilwanyana "iLamotrigine" kwizigulane ezinokuhlutha. Kukho ukugqithisa kwesikhumba kwizigulane ngokuqhelekileyo kwiiveki zokuqala eziyi-8 zokuthatha iyeza. Ngexesha elifanayo, ukusetyenziswa ngokufanayo ngexesha likaValproate (okanye iziyobisi kunye nenkunkuma efanayo) kunokunyusa umngcipheko wecala lomphumo.

Ukuba isikhumba esikhwelweni somzimba sisigcinwa sisigxina, amayeza "uLamotrigine" avunyelwe ukuba angayeki. Kwiimeko ezininzi, i-urticaria iyanyamalala ngokukhawuleza emva kweeveki ezininzi zonyango. Nangona kunjalo, ngokugqithisa okunamandla, isilwanyana "uLamotrigine" oogqirha bavame ukukhansela. Kule meko, elinye iyeza lonyulwa ukuba lonyango lwe-epilepsy.

Ukugqithiswa kwezidakamizwa

Thatha eli liyeza kuphela ngokuhambelana neengcebiso zogqirha. Akukho mzekelo kufuneka udlulelwe kwonyango le "Lamotrigine". Ngaphandle koko, isigulane sinokubonisa iimpawu ezinjalo ezinjenge:

• Utywala;
• Ukulala nokuhlanza;
• Coma.

Kwiimpawu zokuqala zokudlula ngaphezulu, isigulane kufuneka sifakwe esibhedlele. Isigulane esithathile kakhulu "iLamotrigine" ihlanjwe ngesisu kwaye iqhelekileyo imiselwe ukuba isebenzise ikhabhoni ekhutshiwe ukuze isuse i-toxins emzimbeni.

Uphononongo malunga neziyobisi

Iimbono malunga naleliyeza kwiigulane ezinokuhluthwa ziye zaphuhliswa kakuhle. Ukufumana iingenelelo ezipheleleyo zalo mcebisi, izigulane zihambelana nokusebenza kwayo. Ukuthintela isisu kuphelile, ezi pilisi, ngokwezigulane ezininzi, ziyasebenza.

Kuthathwa njengenzuzo ye "Lamotrigine" kunye nokuba akunqabile ukuba nemiphumo emibi emzimbeni wesigulane. Isixhobo esilungeleyo sesilwanyana "i-lamotrigine" ukuhlaziywa kubantu abajongene nokuhluthwa, kunye neendlela ezifanelekileyo zokukhululwa. Emanzini, la macwecwe aphelisa ngokukhawuleza kwaye engenazo zokuhlala. Ukongezelela, eli liyeza lihle kakhulu elivumba (currants). Ingcamango yale mayeza ayilungile. Kodwa kusekunzima ukusela.

Ingqwalaselo ephambili yale nyilisi kukuba izigulane ezininzi zicinga ukuba zixabiso eliphezulu. Kwakhona, ukungaphumeleli kweziyobisi kukuba akunakuthathwa zizigulane ezingenako ukunyamezela i-lactose. Kwezinye izigulane le mpendulo, ngelanga, ayifani. Kwezinye iimeko, akunakunceda, kodwa, ngokuchasene noko, kubangelwa ukutshatyalaliswa. Yingakho, ngaphambi kokuba uqale ukuthatha iyeza "uLamotrigine", kufuneka uqhagamshelane nodokotela wakho.

Indlela yokugcina ngokuchanekileyo

Umhla wokuphela kweengxowa ze "Lamotrigine" yiminyaka emithathu ukususela kumhla wokukhutshwa. Gcina le mayeza kuphela kwindawo emnyama. Ekhaya, ungayifaka, umzekelo, kwinqanaba lokuqala lokunceda. Ukushisa okugcinwa kweziyobisi akufanele kudlule i-25 ° C. Ngoko ke, ehlotyeni, kushushu, imichiza kufuneka ihanjiswe kwisiqandisisi kwireferensi esezantsi.