"Luminal": imiyalelo yokusebenzisa kuzalwa

Yintoni na ichiza "Luminal"? Imiyalelo kunye ezibonisa eli chiza kuya kuxoxwa ngezantsi. Kwakhona chaza iimpawu amayeza beziyobisi, iziphumo zalo ezisemacaleni Izimo.

Ukubunjwa ichiza nokumila

Oko iqulethe iziyobisi "Luminal"? Imiyalelo zokusetyenziswa ithi ukwakhiwa kwale kuqulunqo iquka esisebenza ezifana phenobarbital. indlela Kwakhona ingqalelo iquka amacandelo alandelayo olongezelelweyo: neetapile starch, gelatin, talc kunye calcium stearate.

Ukulungiselela "Luminal", ezibonisa leyo thaca apha, le ithunyelwa ngokohlobo lomgubo elungiselelwe isisombululo ukuba ngenaliti. Kwakhona esi sixhobo zingathengwa ngohlobo lwe kumacwecwe 100 mg, ezo zibekelelwe kwiseli nentaba kunye ezibotshwe ngazo ezenziwe ngephepha, ngokulandelelana.

Isiphumo konwaywa ichiza

Yintoni na le amayeza njengoko "Luminal"? Imiyalelo yokusebenzisa uthi eli yeza kuye, sine thile kunye neziphumo anticonvulsant.

Kujongwa ikwazi medicament unenye inyathelo suppressive (non-ukukhetha) kwinkqubo luvo yabantu, kwaye zinqanda kwindawo ethile (idla sensory) uthinte ukunciphisa umsebenzi weentshukumo, ukuphuhlisa ukozela kunye umthomalalisi.

Drug "Luminal" umyalelo ngokusetyenziswa leyo mfumba yephepha a barbiturate enamandla kakhulu. iimpahla zazo, sine-thile ngenxa inhibition lwe umsebenzi iiseli, nto leyo yenza ukuba ukuyilwa reticular ye eziba le thalamus, brainstem, ngaloo ndlela zinqanda impefumlelwano uthe izakhiwo kunye neuron.

iimpawu iziyobisi

Yintoni na iziyobisi ephawulekayo "Luminal"? Imiyalelo yokusebenzisa (kuzalwa yindlela emiselweyo rhoqo kakhulu) uthi ukulala okubangelwe yile barbiturate, xa kuthelekiswa ne-saline na isakhiwo eyahlukileyo ngokupheleleyo. Njengoko umthetho, uphuhliso isiphumo thile emva kokufaka olu nyango yaqulunqelwa imizuzu 35-65 kwaye ithatha iiyure 6-9.

Asinako ukuba iyeza phantsi imiboniso ingqalelo abuthethileyo iipropati anticonvulsant. Bona zibangelwa impembelelo ichiza kwiindawo ezithile e-nervous system. Xa usebenzisa eli chiza xa izigulane yehle excitability neuronal kummandla epileptogenic onqanda ukuvela kunye nokwanda pulses. Kwakhona kwi imvelaphi "Luminal" uthi ethintela khupha ophezulu rhoqo zemithambo-luvo, ukunyuka nesiqalelo yokulola zombane kummandla motor le neuron.

Ukongeza, ukuba ichiza elinikiweyo iphawulwa sisiphumo esincinane iintlungu kunye antigiperbilirubinemichesky. Kwakhona asikabi ukomeleza yendlela umzimba ukuba ungenwe lula zizinto ezibuhlungu.

iidosi Small "luminal 'abe loo meko, kunye nakumaziko aphezulu umoya Medulla -ugnetayut kunye t. D.

features kinetic

ingaba ichiza ako, "Luminal"? Imiyalelo yokusebenzisa ingxelo ukuba ngaphakathi emzimbeni xa ukhula onokufunxa olucothayo nepheleleyo. Le bioavailability yomenzeli yi malunga ne-80%, kwaye iqhina kwiiproteni plasma - malunga ne-30%.

Le esisebenza beziyobisi ingene ubisi sikanina, kwakunye ngumkhaya. Ngaphezu koko, oko kusiwa kwizihlunu Palsy.

Kukhuthaza "luminal" livela nge izintso ekwimo lingatshintshanga okanye ngohlobo metabolites. Kuba phenobarbital esibonakala sokuzuza kakhulu gqitha. Ukuphazamiseka ezintso kubangela isongezo amanyathelo.

Drug "Luminal": zikhombisa ukuba ukusetyenziswa

Njengento ichiza emiselweyo abadala kuphela, kodwa abantwana kunye kubelekwa. Njengomgaqo, isetyenziselwa:

• hyperbilirubinemia;
• sokuwa;
• ngqi (ngokuba unyango adjuvant);
• nonyango ukuxhuzula zosulele convulsive.

Asikwazi ukuba esi sixhobo kufuneka yabelwe unyango ahlangeneyo njenge iziyobisi umthomalalisi ukwenzela ukuphelisa ixhala, uloyiko kunye ntshikilelo.

Siphelisa ukusetyenziswa

Ngoku uyazi phantsi kweziphi iimeko izigulane emiselweyo iyeza "Luminal". Iimpawu zokusetyenziswa eli chiza zidweliswe ngasentla. Ngokuphathelele Izimo, ngoko ke ukwenza ezifana:

• uvakalelo oluphezulu ukuba ichiza;
• isibindi kakhulu kunye nomonakalo wezintso;
• iintlobo ezahlukeneyo porphyria;
• zisanyisa kunye nokukhulelwa.

Medicament "Luminal": imiyalelo ukusetyenziswa abantwana kunye nabantu abadala

Ukusetyenziswa kweli chiza kufuneka kuboniswe ngokungqongqo. ukusetyenziswa kwayo kufuna kukhethwe irejimeni uqobo unyango, idosi, kunye nexesha apho kuxhomekeke nje kuphela kuhlobo ukuhamba sifo, kodwa kubudala yomguli kunye nezinye iimpawu.

Ngokutsho imiyalelo, izixhobo umlinganiselo esisodwa ingxelo ukuba abadala 10-200 mg. Thatha iipilisi kufuneka ibe amaxesha 1-3 ngosuku.

Njengoko abantwana Usana, kubo ithamo ichiza (kathathu ngemini weight 1-10 mg / kg body) kubalwa ngokususela ubunzima bomzimba.

Ukuba asetyenziselwa ukunyanga uhlobo izifo nokuhlanganiswa iziyobisi, esithathwa omdala 100-1400 mg (iimela emthanjeni), okanye 10-200 mg (ngokuba inaliti intramuscular).

Ukubalwa ithamo kwisifundo amayeza abantwana nayo ayenza isekelwe ubunzima yomntwana.

Ngokutsho kweengcali, emva ulawulo efakwa, "luminal" isiphumo layo eliphezulu ekufikelelwe kuso phakathi lemizuzu engama-35.

imiphumela emibi

Ngaba iimpembelelo ezingalunganga kwi umzimba iziyobisi womntu "Luminal"? Imiyalelo yokusebenzisa (ukusuka mngundo oko kuthetha akayibonisanga) uthi ukuba unyango lwedatha amayeza isigulane basenokuba iindidi side effects ezichaphazela bonke amalungu ebalulekileyo kunye neenkqubo. Iimpawu Ezingalunganga ubuthathaka, ukudinwa, nobuthongo, ukudandatheka kunye Ataxia. Kwakhona kuyenzeka ukuba uphuhliso thrombocytopenia, agranulocytosis, negazi kunye ukuphazamiseka ngecalcium ukutya.

amacala libanda

Ngenxa libanda of "TMB" izigulane rhoqo kakhulu ube yintloko, nystagmus, isiyezi, Ataxia, iingxaki ukuphefumla, silale, ubuthathaka, intetho ongaboniyo, ukozela, utshintsho lobushushu emzimbeni, inkanuko, uxinzelelo lwegazi nezinye ndoyisiwe. Kwiimeko ezinzima kakhulu, kukho: bradycardia okanye tachycardia, nokudumba yemiphunga, ukudideka, arrhythmias, isiqaqa, inyumoniya njalo njalo.

Ukuphelisa ezi mpawu yi lavage emiselweyo esiswini kwakunye unyango ubuthi.

imithi

Ukusetyenziswa koMgaqo-arhente ingqalelo xa zidityaniswe kunye iziyobisi xi HC, methylphenidate okanye mã £ â¨o inhibitor kwandisa uyazikhomba isithako ngendlela ebonakalayo ekwakhiweni plasma, nto leyo ekhokelela ukuba nokwanda isiphumo ziyityhefu kwaye inhibition ye-NA.

Indibaniso "Luminal" kunye corticosteroids, chloramphenicol, corticotropin, dacarbazine, cyclosporine, glycosides digitalis, quinidine, metronidazole, lakhula tricyclic, carbamazepine, anti-nokuhlutha izinto, endingowakhe ukuya succinimides kwiqela, doxycycline, anticoagulants, chlorpromazine, fenoprofenom, ivithamin D kunye phenylbutazone ukunciphisa ixesha isenzo nobushushu kula machiza ukwandisa ukutya kwabo, kwakunye umthwalo ophezu kwesibindi.

unyango ngaxeshanye kunye acetazolamide inokuba negalelo kuphuhliso yamathambo kunye osteomalacia. Valproic acid nelikhuthaza phenobarbital yoxinaniso egazini, nebangela umthomalalisi ngokukhawuleza kwaye silale.

Besebenzisa "luminal" kunye nimodipine, "Verapamil" kunye felodipine kunciphisa ingqalelo egazini.

Ukudityaniswa kwamaxwebhu medicament kunye maprotiline kuphucula ukusebenza kwayo inhibitory kwi-NA, kunciphisa ifuthe barbiturates anticonvulsant threshold convulsive.

Active nto "luminal" paracetamol kunganciphisa ukusebenza kunye nokukhuthaza uphuhliso hepatotoxicity. Xa kudityaniswe folic acid kunciphisa ukusebenza phenobarbital.

Pyridoxine kwandisa igazi abasuka phenobarbital, kunye primidone, felbamate kunye, icala, ukuyikhulisa.

Analogs beziyobisi nexabiso layo

Ichiza ezisisiseko ingqalelo analogue iindlela ezifana "Barbinal" yaye "Dormiral".

Amacwecwe Iindleko "Luminal" (100 mg, 10-PC.) Of engange 1100 nangaphezulu.

ulwazi oluthile

Ngaxeshanye lolwamkelo esikolweni "luminal 'ukusuka ethanol kunye ethanol-kungakwenza kwandisa ngokubalulekileyo isiphumo inhibitory beziyobisi luvo yesigulana. Ngoko ke, iziselo ezinxilisayo kunye nezinye tinctures amayeza etywaleni ngethuba unyango ngala ezingalungile contraindicated.

reviews

reviews Inkoliso yale ukulungiselela abazali babantwana abasebancinane ushiye. Bathi ichiza "Luminal" ukulwa okuhle nezifo ezifana sokuxhuzula kunye neemeko convulsive. Kwakhona kaninzi amayeza isetyenziswa njengenxenye yonyango indibaniselwano, ukufezekisa ntlungu yakhe.

Izigulane ezininzi zithi ukusebenza eliphezulu ichiza "Luminal". Noko ke, ngoko nangoko wathi xa zithe zafunyanwa iimali ezo kufuneka balandele ngqo le idosi idityaniswe yayo kunye nezinye iziyobisi.

Ngamanye amaxesha ingqalelo iyeza esetyenziselwa ekunyangeni abantu DYSTONIA semithambo, nto leyo sikhatshwa maxa uphaphazele. Unyango esi sixhobo kunceda ukubuyisela imeko yomguli, ingakumbi xa yayi amayeza ezongezelelweyo, dilates imithambo yegazi nokuphelisa aqaqambayo.