Ziluma "cortisone": imiyalelo ukusetyenziswa, inkcazo iziyobisi, ncomo

Ngelishwa, izifo yokukrala amalungu kunye neenkqubo ezahlukahlukeneyo neze lwepaki. amayeza Modern linikeza amayeza emininzi ukulwa komtshiso oko. Kwaye kwezinye iimeko, oogqirha amisele kwizigulana njengenimba "cortisone". Le ichiza ayisayicinezeli kuphela uphuhliso ukudumba, kodwa abe iipropati ucaca iintlungu.

Ngoko ke eli yeza? Indlela ichaphazela umzimba? Ngendlela echanelekileyo ukuba bafake? ingaba unyango lu dityanisiwe naziphi iingxaki? Iimpendulo zale mibuzo bakhangela izigulane ezininzi.

Isakhiwo kunye Nokuhlanganiselwa

Ukulungiselela "cortisone" ikhutshwa ngohlobo zokumiswa lolawulo intramuscular. Kwikhemesti unako ukuthenga ezineengqayi iglasi equlathe ml 5 isisombululo. Eyona nto iphambili esebenzayo sisiyobisi ngokohlobo acetate cortisone - a glucocorticosteroid eyenziweyo eye iipropati anti-ukudumba. Uyondelelwano lwee- isithako esisebenzayo-2.5% (kwenye ml lokunqunyanyiswa iqulethe 0,025 g).

Hi ndlela leyi, ezikhemisti nabo ukuthengisa iipilisi, namafutha aqholiweyo ulusu kunye uxakaxa imifinya, njengenxalenye olune cortisone.

Yintoni iimpawu ichiza?

Cortisone ichaphazela ukutya kweziyi kunye carbohydrate. Umzekelo, oku kuphungula isixa iiprothini kwiinkqubo plasma yokubola kwandisa izinto iiprothini esihlunwini, kodwa, kwangaxeshanye, iyazingenela njini iiprothini wesibindi nezintso kwizihlunu. Cortisone kwakhona ulawula inkqubo cleavage ye asidi acid esibindini ngqo kuchaphazela iinkqubo nucleic acid ukutya.

Kwakhona, cortisone, njengezinye corticosteroids, oko kuchaphazela ukutya ekudleni, ukunikezelwa umfutho glucose ukusuka kwesibindi egazini, ibalekisa iinkqubo Yindibanisela kwezinye aminotransferases kushukumisa ukuyilwa izakhi acid ezivela protein yokubola. Ngenxa yoko, izinga glycogen anda kwizihlunu kunye wesibindi, kuphucula kukufakwa carbohydrate emathunjini, sinciphise ukunyamezelana iswekile yegazi.

Le into abangaphangeliyo iinkqubo njini hyaluronidase abangaphangeliyo ukuba Yindibanisela izinto kwizicwili, ukunciphisa capillary permeability, abangaphangeliyo uphuhliso negazi, retards sodium kunye potassium zinomgutyulo ibalekisa iinkqubo ze eziphilayo kunye nokuveliswa le asidi okunamafutha aphezulu.

Kwezinye iimeko, ichiza kusetyenziswa? Ubungqina obubonakalayo buxela ukuba isitofu

Izigulane ezininzi anomdla umbuzo xa kuyacetyiswa ukuba kusetyenziswe ichiza "cortisone"? Ntoni na kuyanceda? Enyanisweni ke, kubonakala ukuba ukusetyenziswa kweziyobisi eninzi:

• isifo samathambo kunye rheumatism;
• Izifo collagen (izifo ekhatshwa sisilonda esidumbileyoesingaphakathi nemithambo kunye zomzimba nokuqina);
• somoya;
• mononucleosis esosulelayo;
• ezinye iindlela wegazi;
• neurodermatitis, nangokhwekhwe, ezinye ulusu izifo ukudumba kunye nawo;
• zaneleyo umsebenzi adrenal ;
• igazi hemolytic;
• glomerulonephritis;
• hepatitis load;
• kunityumza usethubeni lokuba imvelaphi ezahlukeneyo.

Drug "cortisone": imiyalelo yokusebenzisa

Le ichiza a imvelaphi kwamadlala inamandla kakhulu, ngoko ukusetyenziswa kwalo engagunyaziswanga contraindicated ngokupheleleyo. Kuphela ugqirha isitofu amayeza "cortisone" emva ukuhlolwa ngokucokisekileyo. Imiyalelo yokusebenzisa iqulethe iinkcukacha kuphela ngokubanzi. Irejimeni idosi ixesha unyango azimisele ngokungqongqo ngabanye.

Ukunqunyanyiswa unako maliqhutywe intramuscularly okanye athathwa ngomlomo. Xa kuziwa ulawulo ngomlomo, ithamo ekucetyiswa ukuba izigulane yi 0.1-0.2 g wenkqu esebenzayo ngosuku, ekufuneka yahlulwe 3-4 imisitho. Njengoko yokuduka iimpawu eziphambili iidosi liye lancitshiswa ubuncinane - 0.025, isenzo beziyobisi ithatha malunga 6-8 iiyure.

Intramuscularly aziswa 0.02-0.05 g ngosuku. Ukuba kuyimfuneko, esi sixa yahlulwe kabini: "cortisone" iinaliti ezenziwe emva kwesithuba iiyure 8-12. Le nguqu ithatha malunga 12 iiyure.

Ziluma "cortisone" yenza umsebenzi wezempilo esibhedlele. Isigulana kufuneka ahlale phantsi kweliso lomgadi oogqirha njengoko kukho umngcipheko basabele ezibi. unyango "cortisone" ikhutshwa phandle, yaye wezifo - idosi yemihla ngemihla uzimisele ngokuxhomekeke kubudala nobukhali imeko yomntwana.

Ithamo iphezulu yemihla ngemihla ukwimo esebenzayo kuba abadala 0.15-0.3 g

Ingaba kukho naziphi na Izimo?

Akuthandabuzeki ukuba, imbambano ebalulekileyo kukuba nokuba esi sixhobo na ezinye imida kwi sicelo. Medicine "cortisone" zingasetyenziswa hayi kuzo zonke iimeko. Izimo kwindawo yayo zezi:

• iintlobo okunzima lwegazi, apho sikhatshwe ukunyuka ziqhubeke uxinzelelo lwegazi.
• utyando yakutshanje.
• Diabetes osegazini.
• insufficiency yegazi Isigaba sesithathu.
• ubudala nangaphezulu.
• amanxeba wenze le lokugaya.
• Ifom esebenzayo sephepha.
• Negcushuwa.
• izifo egazini fungal.
• izifo kwi nezintso nomhlehlo wesibindi.
• isifo ndlala.
• Vula-angle glaucoma.
• Osteoporosis (e izigulane abafumana glucocorticoids ukonakala kunokwenzeka).
• Hypersensitivity nakweliphi na amacandelo amayeza kulo.
• iqhosha Recent engabalulekanga.
• isifo Cushing kaThixo.

Ziluma "cortisone" Kwakhona contraindicated kwabasetyhini ngexesha lokukhulelwa. Ukuba sithetha ngexesha lokwaphusa, ukuncancisa ngexesha unyango kufuneka uphazamiseke. yobudala yabantwana ayisiso contraindication, kodwa ukusebenzisa 'cortisone "kwi wezifo ngenyameko kakhulu.

Uluhlu yokusetyenziswa kwamachiza

Njengokuba phantse nasiphi na isiyobisi kwamadlala, ichiza "cortisone" inokukhokelela kwezinye ziziphumo ebezingalindelekanga, kubandakanywa kakhulu ngokwaneleyo:

• iintlobo ezahlukeneyo negazi lakho, kubandakanywa ukudumba, irhashalala, isikhumba ukuba bomvu, urticaria, angioedema, ezinqabileyo - umothuko anaphylactic.
• Ziluma "cortisone 'ukuze sikhatshwe inkangeleko ukudumba kwaye bomvu kuyo inaliti.
• syndrome Cushing kaThixo, nto leyo sikhatshwa ukwanda ubunzima bomzimba, ukwanda ubu amathambo nokwehla iintshukumo zesondo.
• Hirsutism - hairiness kakhulu kwabasetyhini.
• Induna.
• Kwamathambo kunye kwamathambo ezizenzekelayo ngenxa ukuba buthathaka kwezihlunu ithambo.
• Zonke iintlobo ukuphazamiseka kwengqondo.
• Sophele pancreatitis (ukukrala kwe-pancreas, nto leyo sikhatshwa ukopha kakhulu).
• isifo isilonda Peptic le lokugaya.
• Perforation izilonda asibonakali.
• Ukopha lokugaya.
• Ukwanda uxinzelelo lwegazi.
• Muscle yoma ngenxa yokuwa iiprothini.
• diabetes steroid.
• Arrhythmia, ukusilela intliziyo.

Kufuneka kuqatshelwe ukuba iingxaki ngasentla zophando waphawula kuphela kwimeko yosetyenziso elide amathamo iziyobisi enkulu (ngaphezu kwe-0.1 g cortisone ngamnye ngosuku). izitofu Multiple akungekwazeki ukuba ukuphazamiseka ezinkulu ezifana emzimbeni. Noko ke, ukuba ngexesha unyango uphawula akukho kubola, ngoko ingxelo ukuba ugqirha.

analogue iziyobisi

Ngenxa yezizathu ezahlukahlukeneyo, asizizo zonke isigulane iyeza esifanelekileyo "cortisone". Analogs it on kwimarike amayeza mihla zikhona, kwaye ngendlela lwezitofu, iipilisi, izithambiso, amafutha kunye ezifana. D. Ingakumbi, amayeza mihla usebenzisa iziyobisi ezifana "Betamethasone", "prednisolone", "Mezipredon", "Dexamethasone" and " hydrocortisone ". Onke la machiza kufuneka malunga iimpawu ezifanayo "cortisone". Kodwa ke ngenxa yokuba benza emzimbeni kunye ngegalelo lazo, khetha naleyo kwananwe ngayo ugqirha kuphela.

Drug "cortisone": ixabiso

Kuba izigulane ezininzi, ke kwingongoma ebalulekileyo iindleko isiyobisi. Kubaluleke kangakanani iya kuxabisa njengendlela "cortisone"? Ixabiso liya kuxhomekeka kwizinto ezininzi, kuquka kwikhemesti ozikhethele, umzi yokuhlala, niqinile-umenzi, njalo njalo. D. One gutyana kwi ml 5 Ibiza malunga 180-210 engange. Kubangel 'umdla ukwazi ukuba ngokuqinisekileyo kuya kufuneka ikhosi epheleleyo yonyango nina amayeza ngaphezulu - le nkcukacha kuza kufuneka ubuze ugqirha wakho. Kwaye kufuneka uqaphele ukuba kwezinye iimeko, a cortisone akwanelanga, kufuneka sibe ngaphezulu.

Izimvo ezigulane kunye amagqirha

Kakade ke, wonk 'uyazi ukuba ungafumana ulwazi oluninzi luncedo, ngomsebenzi ingcali uluvo kunye ngokutsha izigulane abasele unenzondelelo unyango. ngenene abantu abaninzi ukubona ukuphucuka okukhulu emva kokuba uthotho lwezitofu. Ngaphezu koko, ukuhla okubonakalayo iintlungu kunye nezinye nobunzima kuye kwaphawulwa emva inaliti yokuqala. Kakade ke, kukho ulwazi malunga nophuhliso yeziphumo ebezingalindelekanga kwizigulane, kodwa ke ezi meko azikho rhoqo kangaka. Olunye uncedo kule Isisombululo ixabiso elifanelekileyo kakhulu.

Oogqirha ngokwabo ukuphendula kakuhle namayeza. Kwelinye icala, "cortisone" xa kuthelekiswa nezinye glucocorticoids, amaxesha amaninzi kubangela iingxaki. Kungenxa yoko le nto oogqirha mihla ngakumbi amisele analogue drug-isizukulwana esitsha, nto leyo ibe nefuthe zamva emzimbeni.