Allopurinol, Umyalelo wokuba isalathiso, idosi, iziphumo ebezingalindelekanga kunye Izimo

"Allopurinol", umyalelo luchaza njengabayekisiweyo ngohlobo lwe kumacwecwe 100 mg. Libhekisela imithi ichiza protivopodagricakih kuthetha abangaphangeliyo ukuba Yindibanisela uric acid. Ngokutsho isakhiwo "allopurinol" yinto analog of hypoxanthine, transcriptase enkulu inhibitory leyo inxaxheba kukwenziwa uric acid. Ichiza "allopurinol" ncomo qinisekisa ukuba kuchaphazela sokuchitha iityuwa acid uric, xa kuyekwa kwezemfundo kwabo kwizihlunu zomzimba kunye nezintso.

"Allopurinol" umyalelo ku ubungqina

Ichiza emiselweyo:
lokuthintela, ngokuphatha sifo kunye hyperuricemia (kubandakanywa ukusilela enzima kwezintso) isifo nephrolithiasis ,, urate nephropathy;
amatye calcium oxalate kwezintso ile hyperuricosuria;
kwinqanaba urate ophakamileyo, kwakheka ngenxa yokuba ukuphazamiseka enzymatic;
kuthintelo nephropathy etsolo ngexesha cytostatic, unyango radiation le thumba kunye wegazi;
indlala xa zonyango.

"Allopurinol" umyalelo ukuya nomthamo

Ugqirha icwangcisa ithamo ichiza qho ngamnye ngokuxhomekeke
inqanaba urate ibonakele egazini kunye nomchamo, kwakunye uyondelelwano lwee- uric acid. Abadala amisele 100 mg "Allopurinol" ukuya ku 900 mg ngosuku. Le idosi yemihla ngemihla efunekayo ukuba bazohlule babe 2-4 nasebusuku. Ezi tablets kufuneka athathwe emva kokutya.
Abantwana abangaphantsi kweminyaka umthamo 15 yonke imihla ibalwe ngokuchanileyo ngokomgaqo wokubala: 10-20 mg ngalinye 1 kg ubunzima bomzimba umntwana okanye ezilawulwa 100 mg "Allopurinol" ukuya 400 mg.

Ithamo liphezulu izigulana kakuhle umsebenzi kidney ngu 100 mg. Ugqirha kunokwandisa ithamo ukuba yangasemva unyango ihlala kwinqanaba singaguqukanga ophezulu urate ezifumaneka egazini kunye nomchamo.

"Allopurinol" isisikhokelo ziziphumo ebezingalindelekanga

Kwiimeko ezinqabe kakhulu, sibonile nezitenxo kwinkqubo sentliziyo, nto leyo ebonakalisa lwegazi, bradycardia.
iinkqubo ezingahambanga ngokomgaqo ezinokwenzeka kwinkqubo yokwetyisa leyo ziboniswe:
isicaphucaphu, ukugabha, urhudo, ukwanda zezomzuzwana kwi transaminases iqatshelwe serum;
hepatitis, isibindi kwekhono;
stomatitis (in izigulane ngamnye);
steatorrhea.

Kwiimeko ezikude "Allopurinol" amayeza kuye kwabangela ukuphazamiseka kwinkqubo luvo, leyo ziboniswe:
ubuthathaka, ukudinwa, intloko ebuhlungu, isiyezi;
Ataxia, ukozela, ukudandatheka;
isiqaqa, paresis, paresthesia;
uphathwe, peripheral;
ongaboniyo; cataract;
utshintsho isakhiwo papilla optic;
dysgeusia.
kunqabile kakhulu waphawula nezitenxo kwisixokelelwano hematopoietic ukuba kubonakaliswa thrombocytopenia, agranulocytosis kunye anaemia aplastic, leukopenia (iqela lomngcipheko kuquka izigulane ziye zasinciphisa umsebenzi sezintso).

iinkqubo ezingahambanga ngokomgaqo ezinokwenzeka kwinkqubo wokuchama, nto leyo enqabileyo nephritis Embi; kwizigulane ngabanye - nokudumba, uremia, hematuria.

Yokuphazamiseka kwinkqubo yonyango zenzeka kwiimeko ezinqabileyo, nenzalo, namandla, gynecomastia, isifo seswekile.
izifo umzimba lubonakaliswa kwiimeko ezimbalwa hyperlipidemia.
negazi lakho okanye dermatological ezingalunganga.

"Allopurinol" umyalelo kwi Izimo

Akwenzeki ukuba ukumisela iyeza:
enokuphazamisa kwesibindi, zezintso;
Ukukhulelwa ne zisanyisa;
xa kwimeko hypersensitivity kwi "Allopurinol".

Ukuziqhelisa lwezonyango, abantwana abangaphantsi kweminyaka eli-12 ubudala, "Allopurinol" emiselweyo kuphela unyango yamathumba yingozi, xa wegazi, lo gama iingxaki enzyme, ezifana Lesch-Nihena syndrome.