Blocker receptor angiotensin 2: iziyobisi kunye neendlela amanyathelo

Zombini nokuthintela kunye nokunyanga izifo sentliziyo kufuna indlela uxanduva kakhulu. iingxaki ezinjalo nexhala ngabantu namhlanje. Ngoko ke, abantu abaninzi badla awanyange ndijongelwe. Abantu abanjalo badla ngoyaba mhlawumbi ngokupheleleyo imfuneko afumane unyango okanye uthathe iziyobisi ngaphandle kagqirha likagqirha (kwingcebiso abahlobo). Nangona kunjalo, kubalulekile ukukhumbula ukuba ezinye chiza wanceda abanye, oko akuthethi ukuba uza kukunceda. Kuba ukuyilwa iirejimeni zonyango zifuna ulwazi olwaneleyo, izakhono, ngubani na iingcaphephe kuphela. Kwakhona abele naziphi na iziyobisi uyakwazi ukuqwalasela kuphela iimpawu ngamnye yomguli, ubungqongqo sifo, ingakumbi indlela yayo nembali. Ngaphezu koko, namhlanje zininzi amachiza asebenza esifakiweyo esikhetiweyo ndazimisa iingcali kuphela ngayo. Umzekelo, libhekisela sartans - iqela elikhethekileyo iziyobisi (ekwabizwa ngokuba blocker angiotensin 2 receptor). Yintoni na le mithi? Njani le angiotensin 2 receptor? Izimo ukuba ukusetyenziswa kweziyobisi bangamalungu apho amaqela paitsentov? Kwezinye iimeko, kuya kuba kufanelekile ukuyisebenzisa? Zeziphi iziyobisi zibandakanyiwe kweli qela yezinto? Iimpendulo zale mibuzo neminye iya kuxutyushwa kweli nqaku.

Sartana

Ingqalelo njengeqela kwezinto ibizwa ngolu hlobo lulandelayo: blocker receptor angiotensin 2. nemixube eli qela iziyobisi, siye ebangelwe ukufundisisa ezibangela izifo kwenkqubo sentliziyo. Namhlanje, ukusetyenziswa kwabo zentliziyo uya kuya kuxhaphaka kakhulu.

Angiotensin 2 receptor: ezisebenza amanyathelo

Ngaphambi kokuba uqale ukusebenzisa amayeza kagqirha, kubalulekile ukuqonda ukuba zisebenza kakuhle ngayo. iyayichaphazela njani umzimba womntu angiotensin receptor 2? Amalungiselelo eli qela ukubophelela receptors, ngaloo ndlela bavimbe ukwanda okubonakalayo uxinzelelo lwegazi. Oku kunceda ukuba kuthintela lwegazi. angiotensin 2 receptor blocker zezona sisebenzayo eli ngokuphathelele izinto. Iingcali uhlawula ingqalelo ngenxa kubo.

Classification: angiotensin blocker 2 receptor

Kukho iindidi sartans eziliqela nezahlukileyo kubume yemizimba yethu. Kuyenzeka ukuba ukukhetha receptor blocker ezifanelekileyo angiotensin nomonde 2. Iziyobisi, nto leyo eza adweliswe ngezantsi, kubalulekile ukuba baphonononge kwaye baxoxe ngokufaneleka kokusetyenziswa labo kunye nogqirha wakho.

Ngoko ke, kukho amaqela sartans ezine:

• Biphenyl tetrazole yezabelo.
• Nebifenilovye tetrazole yezabelo.
• netetrazol Nebifenilovy.
• iikhompawundi Non-elibujikele.

Ngoko ke, kukho iintlobo ezininzi zezinto zokufunda, izinto ezo ezahlulwe angiotensin 2. imixube (core uluhlu) receptors inikezwe ngezantsi:

• "Losartan".
• "Eprosartan".
• "Irbesartan".
• "Telmisartan".
• "Valsartan".
• "Candesartan".

Ubungqina obubonakalayo buxela

Thatha eli qela kwezinto kube kumiselwe kuphela ngugqirha. Kukho iimeko ezininzi apho bekuya kuba sengqiqweni ukusebenzisa angiotensin blocker receptor 2. iinkalo kwezonyango eli qela amalungiselelo zilandelayo:

• Kwegazi. Oko kukuthi, esi sifo uthathwa isalathiso enkulu ukuba sartans ukusetyenziswa. Oku kungenxa yokuba blocker angiotensin 2 receptor musa ichaphazele ukutya uze ungabi sisizekabani erectile kwekhono, inyumoniya akuphazamisi permeability. Isiphumo ichiza luqala emva kweeveki ezimbini ukuya ezine emva konyango.
• ukusilela Heart. Angiotensin 2 receptor blocker zinqanda intshukumo kwenkqubo renin-angiotensin-aldosterone, ogama umsebenzi kwaye kuphakamisa uphuhliso sifo.
• Nephropathy. Ngenxa iswekile sinwenwa kunye noxinzelelo lwegazi, kukho ukuphazamiseka kakhulu ekusebenzeni nezintso. angiotensin 2 receptor blocker ukukhusela amalungu yangaphakathi kwaye akukho nako ukubonisa protein eninzi yokuchama.

"Losartan"

into esebenzayo ifakiwe iqela sartans. "Losartan" - blocker, angiotensin-2 receptor umahluko sayo kwezinye iziyobisi ukwanda kakhulu ekusebenziseni nokunyamezelana ngabantu abahluphekayo sisifo sentliziyo. Iziphumo ichiza iba ubuninzi sele emva kweeyure ezintandathu ukuthatha amayeza. Yifuna ekufikelelwe kuso emva kweeveki ezintathu okanye ezintandathu isicelo iziyobisi.

Yayibubungqina ephambili ukuba ukusetyenziswa kweziyobisi sikuwo zezi zilandelayo:

• Ukungaphumeleli intliziyo;
• wegazi;
• ukwehliswa amathuba okuba nestroke kwi izigulane kuba ezona zinto zifuneka kuqala ukuze oku.

Awunakusebenzisa "Losartan" ngexesha nokuzala kwaye ngexesha uncancisa, njengoko kunjalo kwimeko uvakalelo ngamnye ukuya amacandelo ngamnye yokulungiselela.

receptor blocker angiotensin 2, ukuba nobhaliweyo ichiza ingqalelo kungabangela ezinye iziphumo ebezingalindelekanga ezifana nesiyezi, sokulibala, ukuphazamiseka kokulala, incasa, umbono, lafa, ukudakumba, memory disorder, pharyngitis, khohlo, iphika, nokuthimliswa, isicaphucaphu, gastritis, bamazinyo, utyatyazo, ukudla, ukugabha, amahlaba, samathambo, iintlungu apha emagxeni, emva, imilenze, iyangongoza, ianemia, kwekhono sezintso, namandla, buthathaka yobuntu, erythema, alopecia, irhashalala, ukurhawuzelela, ukudumba, ifiva, sifo, hyperkalaemia .

Ukuba kuthatha ichiza kanye ngemini, nokuba isidlo, ngokwemithamo emiselwe ngugqirha khona.

"Valsartan"

Le medicament ekhoyo iyasebenza ekunciphiseni hypertrophy kwentliziyo, olwenzeka ngenxa kuphuhliso lwegazi. Ukurhoxiswa aliveli emva ukupheliswa ichiza, nangona kunokubangela ezinye angiotensin receptor 2 (inkcazo sartans iqela kunceda ukuze ufumanise ukuba kanye indlela amayeza ziquka oku phawu).

Yayibubungqina ezingundoqo kokufumana iyeza emibuzo le miqathango ilandelayo: iposi engabalulekanga, hypertension lokuqala okanye ezenqanaba lesibini, ukusilela intliziyo congestive.

Amacwecwe zithathwe ngomlomo. Kufuneka makaginywe ngaphandle ukuhlafuna. Yedosi umisa ugqirha. Nangona kunjalo, inani eliphezulu into anokuthatyathwa emini, angamakhulu amathandathu mane milligrams.

Ngamanye amaxesha abanokuzifumana emzimbeni kunye nefuthe elibi angiotensin receptor blocker 2. Iziphumo ezingalindelekanga, esinokubangela "Valsartan": yehle yobuntu, ukurhawuzelela, isiyezi, neutropenia, ilahleko osezingqondweni, sinusitis, sokulibala, myalgia, urhudo, ianemia, ukukhohlela, iintlungu phaya emva , vertigo, isicaphucaphu, vasculitis, nokudumba, nokuthimliswa. Ukuba ngaba wehlelwa nayiphi na kwezi khemikhali, kufuneka kwaoko andibhekisanga yincutshe.

"Candesartan"

ekuqulunqeni kujongwa ezavela njengoko iipilisi lolawulo ngomlomo. kufuneka ubuhluthayo kanye okanye kabini ngemini kwi esilinganayo kungakhathaliseki ukuba ukutya. Kufuneka ulandele ngenyameko izindululo leengcali. Kubalulekile ukuba ayeke ezithatha ichiza nokuba sele siziva ngcono. Kungenjalo, unako yokungenelela ukusebenza ichiza.

Xa usebenzisa kufuneka silumke kwabo izigulane abaphethwe seswekile, insufficiency kwezintso okanye hatching umntwana. Zonke ezi meko kufuneka aziswe iingcali.

"Telmisartan"

Ingqalelo ichiza ifunxwe ukusuka iphecana zesisu kwisithuba olude elifutshane ixesha. ndinyana, kungakhathaliseki ukuba ukutya. Uphawu esingundoqo ukusetyenziswa yi lwegazi. Isiqingatha-wobomi ichiza iiyure ezingaphezu kwama mabini. Ichiza lithathwe nge amathumbu phantse ingatshintshanga.

Ezingavumelekanga ndiyakuthabatha ingqalelo iziyobisi ngexesha bekhulelwe okanye bencancisa.

Eli chiza ingenza i-side effects zilandelayo: sokulibala, isiyezi, isicaphucaphu, diareyayu, ukudakumba, iintlungu esiswini, pharyngitis, irhashalala, khohlo, myalgia, usulelo womchamo, wegazi, iintlungu esifubeni, iyangongoza, igazi.

"Eprosartan"

kufuneka kuthathwe ingqalelo ichiza kanye ngemini. Imali obacetyiswayo kweziyobisi ukuba isicelo esisodwa angamakhulu amathandathu milligrams. Isiphumo esiphezulu ifunyanwa emva kweeveki ezimbini ukuya kwezintathu ukusetyenziswa. "Eprosartan 'inokuba yinxalenye unyango ezihlangeneyo kunye monotherapy ingxenye enkulu.

Xa kungekho tyala ayikwazi kuqwalaselwa ukuba asebenzise iziyobisi ngexesha zisanyisa okanye yokukhulelwa.

Yintoni iziphumo ebezingalindelekanga kunokwenzeka xa usebenzisa 'eprosartan "? Phakathi kwazo kukho ezi zilandelayo: buthathaka, urhudo, isiyezi, intloko ebuhlungu, nokuthimliswa, ukukhohlela, ukuphelelwa umoya, nokudumba, esifubeni iintlungu.

"Irbesartan"

iziyobisi kujongwa athathwa ngomlomo. Yena ngexesha elifutshane ifunxwe ukusuka phecana zesisu. Le xi liphezulu into egazini kwenzeka emva nje ezimbalwa kweeyure. ekudleni awukuchaphazeli ukusebenza beziyobisi.

Ukuba isigulane eyabelwe wehemodialysis, ayichaphazeli indlela yokusebenza "Irbesartan". Zonke ezi zinto livela umzimba womntu yi olugqitha esikhumbeni. Ngokufanayo, ichiza nga ngokukhuselekileyo ukwamkela izigulana isifo sandla qatha okanye ngcathu.

Ichiza kufuneka makaginywe ngaphandle ukuhlafuna. isicelo sayo Akuyomfuneko ukuba zidityaniswe ndawonye nomnikelo. yokuqala idosi Optimal igqalwa milligrams alikhulu elinamanci mahlanu ngosuku. izigulane abadala Sicebisa abaqala unyango kunye milligrams asixhenxe. Ngexesha unyango, ugqirha wakho angagqiba ekubeni ayitshintshe idosi (umzekelo, indyebo yalo phantsi imeko neziphumo yokungeneli zonyango emzimbeni). Kulo mzekelo, umguli kusenokufuneka ukuba milligrams ezingamakhulu amathathu iziyobisi okanye indawo isiyobisi eziziiprayimari umgaqo. Umzekelo, ukuba unyango seswekile sinwenwa ludidi lwe lwesibini kunye noxinzelelo lwegazi idosi kufuneka ngokuthe mayisuke ingabi milligrams ezilikhulu elinamashumi amahlanu ngemini milligrams ezingamakhulu amathathu (oko kukuthi inani medicament lo ngokukuko yokulawula nephropathy).

Kukho iinkalo ezithile isicelo kweli chiza. Ngenxa yoko, izigulane abaneengxaki balance fluid kunye electrolyte, phambi kokuba unyango ezinye obubonakala kuyimfuneko ukuphelisa (hyponatremia).

Ukuba kukho kophulwa umsebenzi kwezintso, irejimeni yonyango lwakhe ebantwini zinokufana ngokungathi akukho ngxaki. Kukwasebenza kwanjalo kuyo kwekhono hepatic ngobulali ukongamela. Ngelo xesha, lo gama ihaemodialysis mali lokuqala ichiza kufuneka licuthwe ngesiqingatha kuthelekiswa kunye eliqhelekileyo kwaye zenza milligrams asixhenxe anesihlanu ngosuku.

Iingcali azilukhuthazi ukusetyenziswa kweziyobisi ingqalelo senze, kuba akukho kuzinza njengoko ikhuselekile na kwaye isebenza kule minyaka le izigulane.

"Irbesartan" contraindicated ngokungqongqo ukuba ukusetyenziswa ngabasetyhini kuzala umntwana, kuba kuchaphazela ngqo inkqubo Palsy. Ukuba ukukhulelwa ngexesha unyango lwabo, nabokugqibela kumele isuswe ngoko nangoko. Kuyanconywa ukuba batshintshele kwiimveliso ezinye phambi kokuqala yocwangciso lokukhulelwa. Kujongwa ukusetyenziswa kweziyobisi engavumelekanga ngexesha lokuncancisa, njengoko kungekho lwazi ukuba ingaba iyeza ngobisi lwebele.

UPawulos

Gcina impilo yakho - umsebenzi lobuqu ngomntu wonke. Yaye elikhulu ubudala, iinzame kokukhona kuya kufuneka ukuba enze. Noko ke, ishishini lamachiza unalo uncedo gqitha, njalo sisebenzela ukuba ukudala imithi engcono kunye ngempumelelo ngakumbi. Kuquka ukusetyenziswa kakhulu ekulweni nesifo sentliziyo kuxutyushwa kweli nqaku, angiotensin receptor blocker 2. Iziyobisi, uluhlu leyo ezibonisiweyo kuxutyushwa kweli nqaku, kufuneka ingasetyenziswa yaye isicelo ukuya kuyo ugqirha ukuya lowo uwazi kakuhle ngoku karhulumente yesigulane lezempilo, yaye kuphela phantsi kolawulo balo abasisigxina. Phakathi iziyobisi ezifana uyazimela "Losartan" "Eprosartan" "irbesartan" "telmisartan" "Valsartan" yaye "Candesartan". Amisele iziyobisi ingqalelo kuphela kwezi meko zilandelayo: phambi lwegazi, isifo sezintso ukusilela intliziyo.

Ukuba oyifunayo, qala self-Kubalulekile ukuba uzazi ingozi leyo ehambisana nalo njalo. Okokuqala, xa usebenzisa iziyobisi njengento ebalulekileyo ukuze bagcine ngokuchanekileyo idosi kwaye ngamanye amaxesha oluhlaziyiweyo yayo ngokuxhomekeke imeko yangoku yesigulana. Ukwenza zonke ezi nkqubo kuphela sokuqeqeshelwa ngokufanelekileyo. Ekubeni kuphela Ugqirha phantsi zoviwo kunye neziphumo wohlalutyo babela efanelekileyo idosi unyango irejimeni ngokuchanileyo yakha. Emva unyango ukuba iphumelela kuphela xa kuthe ukuba umntu uza kulandela iingcebiso kagqirha.

Kwelinye icala, kubalulekile ngandlela zonke negalelo ekuphuculeni imeko yabo emzimbeni ngokuthi ekuthobeleni imigaqo yokuphila esempilweni. Izigulane kufuneka kakuhle lungisa ukulala kunye kuvukwe, ukugcina imali amanzi, uze ulungise otya (emva konke, ukutya okungafanelekanga, musa ukunika umzimba kunye nezondlo ezaneleyo kubalulekile, abasayi kukwazi ukukubuyisela isingqisho oqhelekileyo).

Khetha amayeza ezikumgangatho ophezulu. Thatha nokuzikhathalela wena kunye nabo ubathandayo. Hlala uphilile!