"Cefoperazone + Sulbactam": imiyalelo ukusetyenziswa, analogs, ncomo

Okwangoku, kukho inani elikhulu zizifo ezosulelayo, eseyiphantse nzima ukuphatha ngaphandle kokusebenzisa antibiotics. Kunqweneleka ukuba ichiza wawukwazi ukuba nefuthe elibi inani elikhulu ezincinane. Ezi ziquka i "Cefoperazone + Sulbactam." ukubazi ngakumbi ezibonisa zokusetyenziswa eli chiza.

ifomu Release komsindo

Ichiza ifumaneka njenge olungumgubo isisombululo. Oku kulawulwa yegazi okanye intramuscularly. Le into esebenzayo na isixa ceftazidime 1 g

Drug "Cefoperazone + Sulbactam" (igama lorhwebo - "Sulperazon" okanye "Sulperatsef") kwaye ulilungu iqela kweziyobisi antibacterial.

Isenzo amayeza ye ichiza

Eli chiza eka ndlela idibene. Medicament "Cefoperazone" i zintsholongwane olubanzi-omoya. Uye waba nefuthe elibi kakhulu izinto aerobic kunye anaerobic amagciwane.

Ukulungiselela "Sulbactam" i ngumqobo lakho beta-lactamases. Oku kuthintela ukutshatyalaliswa penicillins kunye cephalosporins, ekubeni avuleke ezimbaxa intsebenziswano nabo.

Le medicament "Cefoperazone + Sulbactam" abonakalisa isiphumo zezo iiseli ngokuthi ziyibuyisela peptidoglycan, yinto ebalulekileyo iintsholongwane iindonga.

Drug kwazona emzimbeni malunga 8 iiyure umchamo. Isiqingatha-ubomi malunga neeyure ezimbini. Ukuba isigulane ofumana amayeza, ukuhlupheka izifo zesibindi, ngelixa ukunyuka zinomgutyulo iziyobisi.

Code JECFA "Cefoperazone + Sulbactam» - 24.42.11.228. Drug eveliswa in India.

Iimpawu zibonisa ukuba ukusetyenziswa kweziyobisi

Ichiza iboniswe ubukho izifo ezosulelayo ukuba zibangelwa amagciwane ingqalelo into esebenzayo. Ezi ziquka:

• Pharyngitis.
• Tonsils.
• Yomoya.
• ukukrala kwemiphunga.
• Lung ithumba.
• Izifo yenkqubo wokuchama, ezifana Ngokuzimela, ukuvuza ngaphantsi, prostatitis, vulvovaginal.
• izifo ENT.
• zezikhumba nature ezosulelayo: furunculosis, pyoderma, amathumba kunye nabanye.

• Izifo ngaphakathi entlanganweni.
• Nokudumba.
• Meningitis.

Iyeza kananjalo lithathwe njengenyathelo lokuthintela iingxaki iintsholongwane emva kotyando.

Ukulungiselela "Cefoperazone and Sulbactam Dzhodas" lukwabonakaliswe peritonitis, cholecystitis, cholangitis kunye nezinye izifo intra-esiswini. Injongo izovela iziyobisi kunye nexesha unyango kunye nonyango iirejimeni kufuneka azibandakanye kuphela ngugqirha.

Lithetha "Cefoperazone and Sulbactam Spencer" kwakhona wabelwa ngenjongo yothintelo.

Ngubani singacebisi iziyobisi

Nakuba iintlobo ngeentlobo yezenzo, esi sixhobo ayikwazi kwamkelwa phantsi kweemeko ezithile:

• Phambi hypersensitivity ukuya ichiza.
• Ngethuba lokuncancisa "Cefoperazone + Sulbactam" nalo contraindicated.
• ukusilela kwezintso hepatic kufuna isicelo ngenyameko kakhulu.
• Phambi yokudumba ezimbalini yesigulane.

Phambi kokuba baqale unyango nalo eli chiza kufuneka uqiniseke ukuba uxoxe nogqirha wakho phambi Izimo.

imiphumela izigelekeqe ngexesha unyango

Drug "Cefoperazone + Sulbactam" Igama elithi urhwebo "Sulperazon" ngexesha unyango kunokubangela ngokubonakala iziphumo ebezingalindelekanga kulandelayo:

• Kwinkqubo wokuchama basenokuba hematuria.
• nemithambo yegazi angaphendula ekuncipheni uxinzelelo lwegazi okanye vasculitis.

• Uhlalutyo negazi ngexa unyango ngamachiza zidla ngokubonisa ukuhla mpilo, ukuncipha hematocrit, thrombocytopenia, eosinophilia, leukopenia kunye nezinye ezingaqhelekanga.
• amanqanaba albumin Ukuncipha.
• Yibilirubin Encephalopathy kwiintsana olusanda kuzalwa kunye senyongo.
• Ngomhla inxalenye iphecana zesisu ukuze ukuqunjelwa, ukugabha, isicaphucaphu, kwaye wenze pseudomembranous.
• Kwi nesikhumba kubonakala irhashalala, maculopapular irhashalala, kunye ukurhawuzelela kakhulu.
• Izifundo zeLebhu lubonise amazinga banda iimvavanyo umsebenzi zesibindi.
• Amayeza inaliti bomzimba ezikhoyo, xa elawulwa yegazi ngokusebenzisa catheter - phlebitis.
• ukuba okungenani ikhanda, ifiva, kunye nezinye ukusabela anaphylactic kumzimba.

Xa elivela kuzo naziphi na izinto ezingafunekiyo kufuneka baxoxe lo mba kunye nogqirha wakho. Kusenokufuneka ukuba kukhe kuqwalaselwe kwakhona umthamo ichiza "Cefoperazone kunye sulbactam" okanye rhoxisa akatsho.

Yintoni enokulindelwa ne libanda, amayeza

Ukuba uthathe eli chiza phantsi kweliso elibukhali lika gqirha kwabaphilileyo, lo libanda, kufuneka Ungakhathazeki, kodwa self-unyango rhoqo kunokwenzeka. Ukuba umzimba wafumana ichiza kakhulu ngaphezu kufuneka, kusenokubakho iingxaki zezivamvo, kuquka ukugula.

Unyango kule meko yenziwa ngokuhambelana iimpawu. Ngempumelelo kakhulu olugqitha esikhumbeni.

Idosi Treatment Uhlelo

Ukuba amayeza elimisiweyo "Cefoperazone + Sulbactam" umyalelo manual icebisa ukuba bafake ichiza yegazi okanye intramuscularly. Izigulane abadala idosi yemihla ngemihla idla ukusuka grams-2 ukuya ku-4 le-isithako esebenzayo. Le mali kufuneka yahlulwe ngezigaba ezibini.

Ukuba isigulana umntu usulelo idosi kakhulu angandiswa 8 grams, ekufuneka yahlulwe amathamo amabini ngosuku. Ukuba akukho izifo ezinxulumene ezingapheliyo, inkoliso izigulane, kwaye idosi yemihla ngemihla-mali ka-12-16 grams kukunyamezela ngaphandle iziphumo ebezingalindelekanga abonakale.

Ubude uthomalaliso emiselwe ngugqirha. Ngokomzekelo, xa urethritis nokunga gonococcal zilawulwa ngexesha elinye-500 mg beziyobisi.

Ngenjongo yokuthintela yeengxaki emva yokulungiselela kotyando yenziwa umguli 1-2 g butofelwe iyure enye phambi kokuba umsebenzi. Le ithamo ukuze kuphindwa emva kweeyure ezili-12. Ukuba utyando lwenziwa kunye basengozini yeengxaki ezifana usuleleko, ulawulo umbala uqhubeka kwiintsuku ezi-3 emva kwenkomfa.

Izigulane ziphazamiso kwi kidney, iziyobisi "Cefoperazone + Sulbactam" wabelwa kwi umthamo hayi ngaphezulu kwe-4 grams ngemini. Ukuba kukho iingxaki kwesibindi, ithamo lifinyele nokuba kabini.

Ekubeni ichiza nga kubhalwa yegazi kwaye intramuscularly, kukho ezinye iimpawu kwisicelo sayo.

Xa iphathwa yegazi nje kuphela ukuba umgubo zingasetyenziswa:

• 5% solution dextrose.
• Saline.
• amanzi wawuqalekisa ukuze ngenaliti.

Xa kulawulwa yegazi, umgubo kwi igutyana omnye kufuneka ichithwe xa ml 10 kuphela efanelekileyo. Kuyimfuneko ukuba alinde zokuchithwa epheleleyo kwaye ichiza ezilawulwa ngokucotha phezu imizuzu 3-5.

Ukuba zivuze amayeza "Cefoperazone + Sulbactam" yemiyalezo icebisa 1 gram ye isithako esebenzayo. Oko kukuthi, okuqulathwe igutyana enye iqhawulwa ml 5 amanzi ngenaliti, uze udibanise kumxube iimela, nto leyo xi ku 20-100 mg / ml. Ezinikiweyo zesixa isisisombululo athontsize, ixesha ukuxhaphaza inokuba ukusuka kwimizuzu engama-10 ukuya kwi-30.

ulawulo Intramuscular ukunyibilikisa umgubo lungasetyenziswa nokuba ngamanzi ngenaliti okanye sodium chloride. Umlinganiselo ngokubanzi kusetyenziswa ngolu hlobo lulandelayo: 0.5 g imveliso ukuthatha ml-2 kuphela.

Ekubeni xa amayeza ezilawulwa ngokuqhelekileyo kwenzeka intlungu kuyo inaliti, kucetyiswa ukuba ekulungiseleleni sisombululo iziyobisi kongezelelwa "Lidocaine 2%", kodwa kuphela phantsi komqathango wokuba isigulana ayikho bayaliwa ichiza.

Kuba nasiphi na isifo esosulelayo iinaliti ukunika nemiphumo emihle ngokukhawuleza, ngoko ke izitofu ziqhutywa "Cefoperazone + Sulbactam." Iipilisi nabo ngokucotha kakhulu.

Ukusetyenziswa kweziyobisi ebantwaneni

Abantwana badla sigula zizigulo ezosulelayo apho kungekho antibiotics nje ayikwazi ukukwenza. Ithamo yemihla ngemihla ukwimo cefoperazone engundoqo esebenzayo kufuneka ibe ukusuka mg-50 ukuya 200 ikhilogramu ubunzima umzimba umntwana ngamnye. iziyobisi alawulwa ngurhulumente kufuneka lilingane iinxalenye ngokwahlula ngezigaba ezibini.

Desirably, umthamo zonke ayidluli 12 F. Xa iyeza le lesitofu bolus, iyunithi idosi kufuneka ngaphezu kwama- 50 mg / kg.

ezisand nayo maliqhutywe 50-200 mg beziyobisi ubunzima bomzimba kilogram ngalinye, ebabela ibe nezigaba ezibini iiyure ezili-12. Ngokusekelwe iminyaka emininzi ngokoqobo isixhobo kwi unyango kwabantwana, kunokuthiwa ukuba amathamo ukuya ku-300 mg kwekilogram ubunzima bomzimba ngosuku ngasinye ukunyamezeleka kakuhle kids, nkqu phambi kwegciwane meningitis.

Ukusetyenziswa kweziyobisi ngexesha lokukhulelwa

Medicine ne zithako ceftazidime esebenzayo zamiselwa amabhinqa sikhundla kuphela xa loo ithi apho amangenelo umama okhulelweyo izihlandlo eziliqela obungaphezu ingozi umntwana okhulayo. Ukuba ufuna ukusebenzisa iyeza ngexesha lwebele-zokuxheshisela, ugqirha uza isiphakamiso ngeli xesha ukutshintshela usana yokondla ngumntu.

Intsebenziswano kunye namanye amachiza

Drug "Cefoperazone" kwiipropati yayo amayeza nje edityaniswe i aminoglycoside. Ukuba kukho imfuneko kwi kunyango kula maqela mabini iziyobisi, kodwa zilawulwa ngendlela kulawulo uveza nge catheter ezimbini ezahlukeneyo.

Co-zolawulo isiyobisi kunye thrombolytic, antiplatelet kunye NSAIDs kwandisa umngcipheko ukopha.

Kuba izigulane ezineengxaki zezintso kwi yokwamkela medicament "Cefoperazone Sulbactam" kunye aminoglycosides kunye womchamo zophuhliso izaliswe of nephrotoxicity.

Ngexesha therapy with "Cefoperazone" ezingafunwa ukuba usele utywala, kungenjalo kungabangela ezi mpawu zilandelayo:

• Isicaphucaphu.
• Ukubuyisa.
• yintloko ebuhlungu.
• Tachycardia.
• ukwehlisa uxinzelelo lwegazi.
• iintlungu esiswini.

Phambi kokuba uqale unyango nalo eli chiza, kufuneka wazise ugqirha wakho ukuba uthathe onke amayeza ngalo mzuzu.

Kufuneka wenze ntoni ukuba contraindicated lithetha "Cefoperazone"? Analogs singavala kakuhle naye.

Ezinye bokuqonda ngokusebenzisa ichiza

Ngexesha unyango kunye olu nyango kufuneka silumke ngakumbi kwabo izigulane kufuneka negazi badla waphawula. Umngcipheko yale uvakalelo kunyuke igcwele nokuba ebulalayo. Ukuba ngexesha therapy bephawula ukusabela nokuba minor kukwalisa, ichiza "Cefoperazone + Sulbactam" kufuneka iphakanyiswe kwangoko afake ngezinye iindlela.

Ukuba isigulana unezinga kakhulu kwimiqobo ye phecana biliary, izifo wesibindi nezintso, oko kufuna iingxaki uhlengahlengiso idosi ngamnye. Phambi lomonakalo kwezintso kunye hepatic kufuneka rhoqo esweni xi ukwimo isiyobisi ngokukhutheleyo serum. Nokuba ngaphandle ithamo yolawulo mayingagqithi 2 grams ngemini.

Kwezinye izigulane ngexesha unyango with "Cefoperazone" ekuphuhliseni vitamin K imibala ubukhulu becala, le ngxaki wabonakala abo ukutya enesiphako, malabsorption, okanye ukubandezeleka ixesha elide phezu ekondleni efakwa. Izigulane siphathwa kunye anticoagulants, imfuno rhoqo iliso ixesha prothrombin, kwaye, ukuba kuyimfuneko, atyumbe kwabaza vitamin K.

Ukuba ufuna ikhosi elide yonyango, "Cefoperazone", kunokwenzeka ukuba kukwandisa micro-eziphilayo ezingezizo kalula lo medicament. Kufuneka esweni ngamaxesha lwezalathisi ze ukusebenza enyama yangaphakathi, ingakumbi isibindi, izintso kunye hematopoiesis. Oku kubaluleke ngokukhethekileyo kwi kunyango neonates, iintsana iintsana kunye neentsana ngaphambi kwexesha.

Ngexesha unyango kufuneka uyeke ukuqhuba yaye ekwenzeni imisebenzi efuna ingqalelo engakumbi.

analogue iziyobisi

Xa siqwalasela nasiphi na isiyobisi, amaqela amabini ukuze kuchazwe kumlungiselela analogs kunye ntonye. Kuba ntonye ziquka amayeza kumafa yabo eyona nto efanayo esebenzayo. Kuba "Cefoperazone" iziyobisi, ezi zezi:

• "Bakperazon".
• "Sulzontsef".
• "Sulmomer".
• "Sultsef".
• "Tsebaneks".
• "Paktotsef" kunye nabanye.

Xa sithelekisa medicament "Cefoperazone" analogs linokuba ngaphezulu amacandelo, nto leyo kunye into engundoqo nemiphumo eyahlukileyo kancinane. Kungenxa yoko le nto ukhetho iziyobisi ezinjalo kufuneka wasondela ngenkathalo size sizamkele kuphela kagqirha.

Elinye iqela analogue amayeza kunye intshukumo efanayo imithi. Ukuba uthathe iziyobisi "Cefoperazone + Sulbactam" analogue beli qela zezi:

• Powder "Azaran" ngenxa izitofu efakwa.
• "Axons."
• Olungumgubo Inaliti "Bestum".
• "Vitsef".
• "Klaforan".

• "Kefoteks".
• "Tsedeks" njengezingxobo.
• "Tsemideksor" (tablets).
• "Tsefantral" kunye nabanye abaninzi.

Nokuba neziphumo ezifanayo amayeza beziyobisi ngenxa izinto ezahlukeneyo esebenzayo kunokuba neziphumo ezahlukileyo umzimba, ngoko musa ukukhetha amayeza zabo, ezisekelwe phezu imiyalelo ukusetyenziswa.

baqinisekiswa

Abo izigulane zange nakanye zabhenela "Cefoperazone + Sulbactam" kweziyobisi ukuba unyango lwezifo ezosulelayo, wathi ukusebenza kwayo phezulu. Abantu abaninzi bathi ukuba izifo genitourinary enyangekayo ngokukhawuleza ngaphandle iingxaki.

Umama kids ushiye iziyobisi pro "Cefoperazone" ncomo kakuhle HIV. Yafumanisa ukuba abantwana umvumela ichiza kakuhle nokuba phambi co-morbidities. Kufuneka wakhumbula ukuba unyango olunjalo kufuneka lwenziwe kuphela esibhedlele, ingakumbi kubelekwa.

Ukwamkelwa kwalo naliphi zintsholongwane kufuna ingqalelo ngakumbi kumsebenzi kwenkqubo yokwetyisa. Kukugcina intsalela microflora, kungakuhle ukuba ngaxeshanye ukufumana amayeza afanelekileyo, umzekelo, "Linex". Lo mbuzo kuhlala uxoxe nogqirha wakho.