Creatinine ephakamileyo. Ntoni oku kuthetha nendlela ukuba intsebenzo zibuyele esiqhelweni

Creatinine - imveliso ekupheleni nitrogen ukutya. Esi salathisi ikuvumela ukuba ukulandelela umsebenzi ezintso kunye nemisipha umzimba wethu. Ngokutsho inqanaba imveliso (kuba oku kufuneka uvavanyo igazi creatinine) kuyabonakala kwi excretory umsebenzi kwezintso kunye nemeko ijwabu kwezihlunu. It senziwa izihlunu, ngoko kukhululwa ngqo igazi idubule ukusuka izintso zomzimba kunye nomchamo.

Indlela elula efumanise kwezifo ezininzi uvavanyo lwegazi. Creatinine kwabasetyhini (umgangatho) kancinane kumazinga asezantsi ngabantu (imali yayo uyahluka 45.5-81.3 mmol / l, amadoda - 61.3-105.2 mmol / L). Ngoko ke, lo msebenzi ziya kwahluka ngokuxhomekeke ngokwesini. Ukwanda creatinine emadodeni kuba kwemisipha mass baye ngakumbi (yaye ngokubanzi ebantwaneni - 26,0-61,5 mmol / l).

Izizathu (basic) ukwanda creatinine:

• Ngokuqhelekileyo, creatinine ophakamileyo, Iimbaleki ezininzi (isixa esikhulu kwemisipha mass), abo bantu badla izixa ezikhulu inyama-besitya, ukuthatha amayeza ( "ibuprofen", "Tetracycline", "Cefazolin").
• ukusilela Acute kwezintso. Kukho izizathu ezininzi ukusilela oyingozi kwezintso. Eyona ziqhelekileyo: umothuko ithi, inkoliso ilahleko igazi, izinto nephrotoxic yityhefu, izifo ezihlasela zosulele sezintso, mushroom Ityhefu, ukwenzakala sezintso abambiseneyo. Iimpawu eziphambili ahlekise ukusilela kwezintso ezi anuria (ukungabikho ukuchama), isicaphucaphu, ukugabha, ukungabi namdla, silale, ababangela iimpawu ezifanayo zesi sifo, nto leyo eyakhokelela ekubeni ukusilela oyingozi kwezintso.

• Ukwanda creatinine njengento enobunzima elikhulu ekutshatyalalisweni kwimicu izihlunu (umz, kuyityumza syndrome). Ngexesha umonakalo izihlunu zethu wakhulula isixa esikhulu creatine ukuba siyafikelela kwegazi, nezintso musani ukuphatha yayo idubule ngokukhawuleza emzimbeni wethu.
• Xa hyperthyroidism kunye creatinine ephakamileyo. Le Pathogenesis ukwanda yokuwa kwimicu kwezihlunu phantsi kwempembelelo obugqithisileyo ihomoni, ndanda autolysis zihlunu kukhokelela ekwandeni creatinine serum.

Ekuchongeni creatinine ophakamileyo ngegazi, ikakhulu ukuze zingabandakanywa ezahlukeneyo izifo zezintso. Ukuze wenze oku, wayeqhuba uthotho lweemvavanyo kunye neemvavanyo ezisebenzayo. An yokwaphuka ebalulekileyo, nto leyo evumela ukuba ukumisela umsebenzi kidney yi sobume creatinine kwedijithali (Rehberg probe). Yiyo le probe indlela ngobuchule yokufumanisa umsebenzi sezintso kuthelekiswa nomlinganiselo elula creatinine kwegazi.

Amanqanaba creatinine igazi kuqala avuke ezichaphazela ngaphezu kwama-50% of nephrons, kwaye ubucukubhede yaguquka kudala ngaphambi kokuba ukwanda creatinine kwegazi.

Ngenxa yoko, ngenxa kule isampuli nga ixilonge esi sifo kwizigaba preclinical kwaye ningazuza ixesha esibalulekileyo unyango ngempumelelo.

Nciphisa izinga creatinine negazi azinako ukuphelisa kuphela unobangela neendyebo zalo, njengoko le Linyuke sisphumo kuphela kwesi sifo. Ukunciphisa aokusetyenziswa ukutya protein-free.