Genetics Ayikwazi Nokunyamezela Cancer

Ezinye iiseli phantse musa lokuyivelisa ngoxa abanye bathi kanye, ngesantya breakneck. Ezinye iiseli musani ukuyeka ichemotherapy, ngoxa abanye ngokuchasene - nangoko kufa. Kodwa kunjalo, ezi seli iqanjwa isakhi efanayo nezesayensi kodwa ukuba ufunde indlela yokulawula ukuze ndiphilise nesifo somhlaza.

Yilaa isiphetho enjalo zinokubonakala kulindixesha ethandwa Science ukuba ababhali isifundo koko acacisa ukuba kweli nqanaba lophuhliso amayeza, izazinzulu zingenako okwangoku ukunikela ihlabathi unyango lomhlaza kwaye ibonisa ukuba amachiza afunyenwe Genetics akayi kuba nako ukulwanabo kwesi sifo.

Njengalo okanye akunjalo, kodwa ke genome somhlaza uyakwazi ukucacisa indlela ukusombulula le meko. Kodwa isifundo esitsha ifumanisa ukuba indlela yokusombulula le ngxaki ayihambelani kulala moya ye-DNA ye sifo. zonyango zangoku zijolise ukuchonga iiseli ezibangelwa kwiDNA baqale ukwabelana angalawuleki. Kubonakala ukuba kufuneka nje ukufumana ezo molekyuli ukuba banoxanduva ukuguquka uze noosokhemesti ukufumana unyango oluya ukumelana nale imithombo sifo.

Ngokusekelwe kule, efana chiza Xalkori Pfizer (umhlaza wemiphunga) kunye Gleevec Novartis (chronic leukemia myeloid). Kodwa ukuze kubekho ixesha (kwaye uqhele) xa la machiza ayeke ukusebenza, njengoko umthetho, kwiimeko ezinjalo ngayo Kucingelwa ukuba iiseli umhlaza zivelise kuguquka elitsha, apho amachiza nje namandla.

Kwesi sifundo, abaphengululi bamangaliswa kukufumanisa ukuba iiseli umhlaza colon ngendlela eyahlukileyo kakhulu, nangona bathe baba ekuqaleni twatse yemfuza waba imvakalelo ukuba lo mahluko kungekho nawuphi na umahluko. Oku kuchasene inkolelo kumaziko ekhoyo ukuthi izakhi banoxanduva imisebenzi leeseli ngamnye ithumba, nangenxa umsebenzi ukuvelisa kwaye abasabela ngayo ichemotherapy.

Njengoko zofuzo Dzhon aali uthi umbhali zesifundo, ukuba DNA - akanguye unobangela kuphela uphuhliso ithumba, siya kuthathwa kuphela ukuba ufuna ukunyanga umhlaza, udinga amayeza, ekufuneka isekelwe iimpawu non-yemfuza.

Ngaphandle kokuya kwi iinkcukacha zesifundo, siphawula ukuba izazinzulu eneneni kumangaliswa ukuziphatha yamathumba umhlaza kwi ikholoni. Njengoko yokusabela ukuya iziyobisi ezikhoyo iiseli umhlaza baziphatha engalindelekanga.

Ezinye iinzululwazi neengcali badumisa yophando ukuxhasa imbono ukuba umhlaza unyango umntu - a bobble enkulu, ingakumbi xa uqwalasela kuhlobo apho thaca kuluntu.

Abanye bakholelwa ukuba japan onjalo bekufanele kulindeleke oko, kuba ukukhula iiseli zomhlaza ixhomekeke parameters ezininzi zangaphandle, kuquka, umzekelo, okusingqongileyo, kwaye baya kuba ngomnye nqobo zokugweba, nto leyo ekugqibeleni iya kubonisa njani ukuba unyango olusebenzayo kwi unyango lomhlaza.

Abaphandi bakholelwa ukuba isizathu: kwisigaba apho iseli (ukuphumla, icandelo, ukukhula); ezilawula imfuza abandakanyeka ngexesha elinye okanye elinye; nokuba kukho ukufikelela kwi-oksijini iseli elithile, kwaye kwezinye iimeko ezingezo-yemfuza.

Umzekelo, unyango ingajoliswa ku Iseli utshintsho sokulala kwisigaba kwisigaba andise, njengoko ungakhuseleki ichemotherapy, apho umgaqo sibhekiswe bystrorazmnozhayuschiesya iiseli.

Izazinzulu zikholelwa ukuba umhlaza kufuneka baphathwe ngokwakhiwa kwinqanaba eziphilayo.