HCG kunye nemisebenzi yazo

Hormone izinto raznostrukturnyh zomgquba ekwaziyo ezichaphazela ukusebenza kumzimba yabantu. iihomoni Gonadotropic kuchaphazela umsebenzi uhlelo zokuzala. Bona kuhlelwe kwi posa sobuKristu, kwaye ukusuka kukho secreted egazini.

Le hormone ye yebhinqa cipande

Ingqondo yebhinqa yahlulwe ezimbini: ngaphambili nangesemva. Ngqo iihomoni ngaphambili kuhlanganiswa secreted kungena egazini. Le ngomva nomhlehlo ingqondo yebhinqa, bavela le ngxenye kwaye secreted egazini phantsi kweemeko ezithile kuphela.

Gonadotropic yebhinqa hormone zivuselela amadlala ngokwesini. Ezi ziquka:

• FSH - follicle-inkanuko hormone. Ixhasa oogenesis kunye spermatogenesis. Ngaba protein leqela (glycoprotein) apho ubunjwe asidi acid inamathele iicarbohydrate.
• LH - luteinizing hormone. Ukhuthaza ukukhululwa beqanda ukusuka isizalo luchaphazela secretion ka emzimbeni ngesondo (estrogen, dlala) kumadoda ebangela secretion of androgens. Isixa hormone yahluka ngexesha elinye lomjikelo sexesheni, kukho secretion umlinganiselo kunye yolunye kukho imali ethile FSH kunye LH.

imveliso hormone oluqhutywa gonadotropah (iiseli basophilic) adenohypophysis. Benza phezulu malunga ne-15% yazo zonke iiseli nomhlehlo sobuKristu.

Pregnancy hormone - HCG

Ukuba ukuchumisa umzila we iqanda eludongeni zesibeleko emzimbeni umfazi iqalisa ukuvelisa iihomoni ezithile yebhinqa gonadotropic thaca chorionic gonadotropin.

Umsebenzi hormone kukugcina corpus luteum umsebenzi (ukhetho estrogen kunye dlala) ukuya ekukhuleni ngokupheleleyo beendawo. Inika isiphumo luteinizing ophezulu emzimbeni, nto leyo kakhulu idlula FSH kunye LH.

iimpawu noshowo hormone

Umsebenzi bemvelo emzimbeni inika isakhiwo eyodwa ezibandakanya subunits ezimbini. Okokuqala, a-enganeno, uye isakhiwo phantse twatse kuzo zonke gonadotropins, lo gama i-b-enganeno inika ithuba elikhethekileyo kule hormone.

Ngabanye, ezi subunits musa ukungqinela nayiphi na impembelelo kwi ephilayo, kodwa xa uqhagamshele, ukuba umsebenzi wabo lomzimba kunye nempembelelo inkqubo ebalulekileyo ephilayo, ingakumbi le nkqubo zokuzala. Ngenxa yoko, iihomoni gonadotropic ibe nempembelelo ebalulekileyo nje kuphela kwinqanaba ngesondo, kodwa kwiinkqubo yonyango kunye nokulawulwa eseleyo hormone.

Hormone kuchaphazela umzimba

Ukususela kumaxesha amandulo, izazinzulu ziye bazama ukufunda umsebenzi bemvelo iihomoni kunye nefuthe lazo emzimbeni womntu. Gonadotropic hormone kuba nempembelelo enkulu phezu iinkqubo kumzimba yabantu. Ngoko ke, ukufunda indlela yabo amanyathelo umbuzo obalulekileyo kakhulu nanomdla. Ekuqhubeni uphando hormone enombhalo kwafunyaniswa ukuba iiseli bayakwazi ukuqaphela iihomoni ezithile uze ubophe kuphela kwiiseli ezithile.

Inkqubo ngokuzibophelela kwi iseli lwenziwa yi kokuba inwebu okanye iiseli ngaphakathi kwemolekyuli protein - receptor. ukwamkelwa Intracellular inxulumene iihomoni steroid, njengoko bakholisa ukungena kungena iiseli kunye nempembelelo umsebenzi wakhe. Ndizayo reception uphawu hormone protein ukuba ubopheleleke ukutyabeka iseli ndizayo.

Ukubambana kwabo kwiproteni hormone receptor ikhuthaza ukuyilwa zakhiwo. Eli nqanaba kwenzeka ngaphandle kokubandakanyeka enqanda, kwaye ingathityazwa. iihomoni steroid faka iseli, bakubophe ukuya receptor. Emva iinguqu kwakhiwa esimbaxa engena ngumongo iseli kwaye ikhuthaza ukuyilwa kwento RNA ethile kwi icytoplasm apho kuyondelelaniswe enzymatic amasuntswana ezibangela ifuthe hormone kwiseli.

iihomoni Gonadotropic: imisebenzi kunye neziphumo kwiinkqubo uhlelo zokuzala

umsebenzi FSH ifikelela liphezulu amabhinqa. Oku kukhuthaza ukukhula iiseli follicular ukuba phantsi kweempembelelo GSIK ndobuyela amaqamza kwaye ivuthwe phambi sigaba ovulation.

Phantsi yempembelelo yokwanda ubunzima amaqanda SFS namasende. Kodwa, nkqu ukuba ziqalise hormone ngumntu zokwenziwa akunakwenzeka ukuba uphuhliso izihlunu Embi, ethi ichaphazele secretion of androgens yendalo wamatyhalarha.

GSIK onoxanduva ovulation kwaye ukuyilwa ovarian corpus luteum. Kananjalo kunye follicle oluvuselela ihomoni oko kuchaphazela secretion estrogen. Phantsi yempembelelo hormone eshukumisa iiseli Embi, kukho ukukhula amalungu anoxanduva iimpawu sex eziziisekondari.

Isiphumo yezinto eziphilayo LTG

LTG iyafana kakhulu hormone ukukhula. Emva laboratory lwabonisa ukuba kule imolekyuli enye, ngoko ke umntu akakwazi ezikhethiweyo ngumfundi, nganye kwezi hormone. Imisebenzi LTG ziquka ubisi secretion kunye yiprogesterone. Kubalulekile ukuba kuqatshelwe ukuba ezi nkqubo zibangelwa impefumlelwano inani elikhulu emzimbeni, ukususela ekubeni umzimba LTG kuphela ezi mpawu Awuveli.

Ngoko ke, ngokuba ulwabiwo ubisi kufuna hormone zilandelayo:

• FSH and GSIK - ukuba secretion estrogen amaqanda;
• phantsi kwempembelelo hormone ukukhula estrogen i ukukhula yobisi;
• LTG ebangela secretion dlala kwi luteum corpus;
• Hormone eshukumisa uphuhliso epheleleyo ingaba mammary kwinqanaba alveolar-lobed.

iihomoni Gonadotropic kufuna intsebenziswano rhoqo ukuqinisekisa ukuba umsebenzi ngokupheleleyo emzimbeni kunye neenkqubo zayo zonke. Kungenxa yoko le nto impembelelo elahlukileyo ngamnye kubo (kwimeko yolawulo iihomoni eyingozi) obangela abasabela kulindeleke.

hormone hypothalamic

Kukhupho yobuchopho gonadotropin yokukhululwa egazini-hormone. Kuye isakhiwo polypeptide kwaye kuchaphazela secretion hormone yebhinqa. Ubukhulu becala oko kuchaphazela hormone luteinizing, kunye follicle ngoko. GnRH iveliswa ngexesha ngamathuba ichazwe ngokucacileyo, nabafazi, isukela imizuzu eli-15 ukuya ku-45 (kuxhomekeka komjikelo), kunye namadoda hormone secreted yi yonke imizuzu engama-90.

Hormone yokufakelwa zokwenziwa nolawulwa dropper yephule umsebenzi secretion ka emzimbeni, ezithi nelifutshane ukwandisa secretion, uze emva koko - ukuba kumiwe ngokupheleleyo zokukhokhela gonadotropins yi yebhinqa sobuKristu.

Inkqubo exposure GnRH kwi eziphilayo

GnRH nqgo inikeza yebhinqa sobuKristu lobe, apho iiseli (gonadotropins) kufuneka GnRH receptor ngqo secretion ka FSH kunye LH iihomoni, mvisiswano leyo, kwelinye icala, kuchaphazela ukusebenza gonads.

PG lukwakhuthaza ekukhuleni isidoda neqanda iiseli, LH ichaphazela secretion ka emzimbeni ngesondo (estrogen, dlala, testosterone). Phantsi impembelelo ngesondo hormone iiseli kwenkqubo sokuzala zivuthwe kwaye zikulungele ukuba isichumiso.

Xa kwemali ngokukhawuleza gqitha iinkqubo spermatogenesis kunye oogenesis inhibin yabelwe eziphembelela iihomoni gonadotropic ze ingqondo yebhinqa sobuKristu khuthaza isantya iinkqubo ekukhuleni gametes ngokusebenzisa inyathelo follicle ekhuthazayo hormone.

Kutheni ukusebenzisa amalungiselelo gonadotropic

Ziyanda e unyango yezonyango ngokwazisa iihomoni ngumntu. Kwezinye izifo yonyango okanye ukuphazamiseka kwenkqubo okuzala lomntu basebenzisa iziyobisi gonadotropins. ulawulo lawo ukuya elithile nefuthe imveliso hormone ngesondo kunye neenkqubo ezenzeka apha emzimbeni.

Kwimeko ke Yindibanisela gonadotrophins basenokuba izifo ezithile ezidalwe (kwezisu ezintathu yokuqala, luhlaza ngokwesondo, infantilism ngokwesondo, panhypopituitarism kunye Sheehan kaThixo syndrome).

Ukulungisa ezi ezimbi, igazi kwenziwa uphando nohlalutyo yokutshintsha amalungu hormone. Ke prescribers eziyimfuneko ukubuyisela imali eyiyo iihomoni kunye, ngoko ke, ummiselo kweenkqubo ebalulekileyo emzimbeni.