Ichiza "Lamikon": umyalelo, ncomo isicelo, analogue, Composition

Ingaba eli chiza njenge "Lamikon"? Ixabiso kweli chiza kuya kwenziwa kweli nqaku. Kananjalo apho uya kufumana imiyalelo eneenkcukacha ukuba ukusetyenziswa kweziyobisi, Izimo zayo, analogs, izalathisi, reactions ezibi, ifom ukukhululwa, isakhiwo njalo njalo.

Ekwakhiweni, imilo kunye nokupakishwa amayeza

Zuza ingqalelo ichiza banokuba ezi fom zilandelayo:

• "Lamikon" zetoti. Isitshizi iqulethe into esebenzayo ezifana terbinafine. Njengokuba amacandelo zale fomu propylene ethers, macrogol cetostearyl Etere 20, benzoic acid, disodium edetate, namanzi wondinika ngemali inaliti Poloxamer 407. iziyobisi epicutaneous ngesi kwibhotile impompo sokulinganisa 25 g.
• Cream "Lamikon" (amafutha). Guide ingxelo ukuba element esebenzayo yale fomu ukhonza terbinafine. Ezinye izithako yale fomu: ezimbiwa oyile, isodiyam hayidroksayidi, iparafini emhlophe ethambileyo, cetostearyl utywala kunye phenylethyl, macrogol cetostearyl Etere 20, propylene ethers, poloxamer 407 kunye namanzi okuhlamba. Ekuthengisweni lamafutha lawo aqholiweyo uza zohlobo lwe-15 g
• "Lamikon" ukulungiselela ngomlomo. Tablets, imfundiso leyo livalelwe kwibhokisi eyenziwe yekhadibhodi, ikwaquka into lo esebenzayo i terbinafine. Ngokuphathelele amacandelo olongezelelweyo, ziquka: umbona starch, isodiyam wesitatshi glycolate, microcrystalline kwincindi, dust colloidal anhydrous, hydroxypropylmethylcellulose nezinki stearate. Amacwecwe ziqulethwe iiseli aya lamaqhosha 7.

pharmacodynamics

iqela amayeza ingqalelo iziyobisi - nokubola. Ngokutsho imiyalelo, eyona nto iphambili yale arhente yi alilamin leyo ebonisa isiphumo esebenzayo kwezonyango kwinani elikhulu Ngeentlobo fungi ezahlukeneyo.

Iimpawu fungicidal of terbinafine (yoxinaniso oqhelekileyo) kwaye zikhutshwe dermatophyte nomngundo, kwakunye ezinye iintlobo zomngundo dimorphic.

Ngokuxhomekeka kuhlobo, nxamnye amagwele le iyeza ukubonisa zombini umsebenzi fungicidal kunye fungistatic.

isimiso ukusebenza

Njani ichiza "Lamikon"? Guide ingxelo ukuba le arhente abangaphangeliyo ngokukodwa kumabakala okuqala sterol biosynthesis kwi imifinya iseli ezinzwaneni. Isiphumo kuzichanaba obuxhasa olwenzeka intracellular of squalene, kunye nokungabikho ergosterol. Oku kukhokelela ekutshatyalalisweni iiseli ezinzwaneni.

Indlela yokusebenza ye imali ezinxulumene ngqo inkqubo inhibition le epoxidase enzyme squalene ezifana, ebhekiselele cytochrome P-450.

Ngokutsho iingcali, iziyobisi "Lamikon" akukho azinampembelelo kwimiphumo namanye amachiza, kwaye nethe hormone.

Pharmacokinetics

Njengoko ichiza ako, "Lamikon"? Guide uthi xa isicelo yokufunxa wengingqi okanye ngokwemixholo into esebenzayo lingaphantsi kwe-5% of idosi esetyenzisiweyo. Ngoko ke, nangokuvela kwalo ngenkqubo esezantsi.

Xa elawulwa ekula ichiza nangoko uqala ukusebenza kwaye isebenza kakhulu ixesha elifutshane (malunga 8-13 iintsuku).

Ngokugcina ukufumaneka wacela ichiza ezinawo corneum ye sangaphandle, leyo yayifunyenwe ngexesha unyango, isenzo fungicidal le medicament kuyaqhutywa iveki enye emva ukurhoxiswa kwayo.

Xa kuthathwa ngomlomo, "Lamikona" into esebenzayo oluhlala eluswini, iinzipho neenwele. Uyondelelwano lwee- ichiza esikule inika ngokupheleleyo iimpawu zayo fungicidal.

Nokufunxwa tablets yi-70%, kwaye bioavailability yawo ingundoqo - 50%.

Ukuqulunqwa efunyenwe kwi-mali ka-250 mg luxinzelelo liphezulu egazini emva seyure. Ixesha isiqingatha-ubomi olusebenzayo imalunga 30 iiyure.

Ukutya kuchaphazela kancinci kuphela bioavailability beziyobisi. Ngenxa protein plasma sibophelela ukuba into esebenzayo ka-99,5%. Amayeza kunokuba ngokukhawuleza ingena dermis kwaye oluhlala kwi corneum ezinawo.

Lodwa "Lamikona" eyenziwa yi amadlala sebaceous. Kwakhona, oko ifumaneka iinwele, ulusu neenwele zoboya. Kwiiveki zokuqala unyango, ichiza ingena plate isikhonkwane.

Terbinafine umzimba ngokukhawuleza cytochrome P 450. Emva metabolites imveliso biotransformation efunyenwe engasebenziyo yi nezintso.

Xa ukungaqheleki esibindini kunye kidney imvume isantya terbinafine ukucola kakhulu, nto leyo ibe xiyimiso ephezulu kwi-plasma.

Ubungqina obubonakalayo buxela

Ukususela ngoko amisele iifom idosi lobulali "Lamikon 'iziyobisi? Amafutha, imiyalelo ukusetyenziswa ichazwa ngezantsi, kwakunye isitshizi unalo okukhomba zilandelayo:

• kolusu fungal, apho zibangelwa fungi ze sodidi Trichophyton, Microsporum kunye Epidermophyton (dermotofitiya iinyawo, nasemiphakathweni, esifubeni, njl);
• multicolor (okanye pityriasis) versicolor, nesuka iimpembelelo Malassezia fungi;
• candidiasis esikhumba, leyo kuxhokonxwa fungi ze sodidi Candida.

Ngayiphi injongo kusetyenziswa iindlela ngomlomo "Lamikon" (amacwecwe) beziyobisi? Iingxelo Guide Yayibubungqina zilandelayo:

• izifo fungal esikhumba, apho ukwanda zabo, namandla okanye ibinzana ukuba aphathwe kanye indlela somlomo (umisela kuphela gqirha);
• intloko mycosis kunye onychomycosis (usulelo nail zenkongozelo).

Kufuneka kuqatshelwe ukuba "Lamikon" macwecwe hayi asetyenziswa unyango ezinemibala (okanye enamaxolo) zoster.

Izimo

Hlobo luni Izimo kufuneka bazazi phambi kokuba usebenzise iziyobisi "Lamikon"? Guide wathi isalelo kuphela elililo zonke iintlobo iyeza ingqalelo hypersensitivity ukuya nempahla yayo.

Ngokubhekisele ithuba ukukhulelwa, yobuntwana kunye nencum-ibele, ukuba Izimo isalamane.

Wamafutha "Lamikon": imiyalelo yokusebenzisa

kweendlela ichiza, ngokutshizwa, aqholiweyo, ibonisa isicelo sabo lwangaphandle. Ngaphambi kokuba uyisebenzise ngenxa unyango lwezifo fungal, kufuneka kuqala icocekile kwaye yome kwimimandla echaphazelekayo ngesikhumba.

Kuxhomekeka nobungozi besi sifo kunye nohlobo pathogen iziyobisi "Lamikon" (amafutha) isicelo kabini ngemini. Kutshizwe isetyenziswa ne-frequency efanayo.

Le cream kufuneka isetyenziswe hayi kuphela ngundo ulusu abachaphazelekayo, kodwa ke kwiindawo abakufutshane. Ukwenza le nkqubo na enqwenelekayo maleko ubhityileyo ngokuthe ngokukhuhla iziciko, linamafutha aqholiweyo.

Ukuba isifo ezosulelayo ihamba kunye ilweyile irhashalala (umz, phantsi kwazo iincum, nasemiphakathweni, ezinqeni okanye phakathi kweminwe), iindawo baphathwa kufuneka kukugubungela igozi (ubusuku).

Ukusetyenziswa kutshizwe

Ndingayisebenzisa njani ukutshiza "Lamikon"? Iingcali Ukubuyekezwa ingxelo ukuba isetyenziswa ubungakanani eyaneleyo yokunyakamisa ngokuthi ngokutshiza kwiinkalo ukuba nqa nomngundo, kwakunye ulusu esempilweni ezikufutshane kuyo.

Ubude unyango kuxhomekeke kumaphepha ubungnqongqo sifo (ukuya kwiiveki ezimbini).

Umfanekiso isigulane uphawule iintsuku ezimbalwa. Ukuze unyango olusebenzayo kudingeka ukuba balandele imiyalelo engqongqo ukuba ukuphoswa esinye isicelo kwaye hayi ukuba ayeke unyango ngaphambi kwexesha. Kungenjalo kukho ingozi ephezulu likakade.

Indlela ukuthatha iipilisi?

iqela amayeza onelungelo amayeza phambi kwethu, kuboniswe imiyalelo. Uthi ukuba ukwenza njani isixhobo.

Njengomgaqo, "Lamikon" iipilisi kubantwana kwiminyaka emi-6 ubudala, kwakunye izigulane abadala. Ukufumana ukulungiselela ngomlomo kuyaqhutywa de Ukunyamalala ngokupheleleyo zonke iimpawu sisifo ezinzwaneni (kuxhomekeka kubume kunye nobukhulu).

Le nkcitho esithathwa medicament ukuba abadala 250 mg, nabantwana ezinobunzima 20-40 kg - 125 mg. Ezinobunzima enkulu umntwana njengoko kumiselwe 250 mg beziyobisi.

Ubude unyango kunye trichophytosis kunye nesikhumba candidosis ziiveki 2-4, yaye olusisikhokelo pedis - iiveki 2-6.

izifo fungal lwentloko aqhelekile ngakumbi ebantwaneni. Ngenxa umthetho, ukuba efanele unyango ukuba ichiza lisetyenziswa iidosi ekucetyiswa ngugqirha inyanga.

unyango Onychomycosis kuthatha iiveki 6 nakwiinzipho 12 - kuba toe isikhonkwane. Phantsi kuncitshiswa ukukhula iinzipho iipleyiti unyango kwandiswe.

ukusabela ezingalunganga

iziyobisi Local "Lamikon", analogue kuzo zidweliswe ngezantsi, kunokubangela iimpawu ezifana exwebula eluswini, ukutsha, ukurhawuzelela, iintlungu, ukutyabuka, nombala kakuhle, erythema kunye uqweqwe Ukwakheka. Kwakhona ukusabela komzimba.

Xa ufumana amacwecwe, imiphumo ezingathandekiyo zilandelayo:

• neutropenia, agranulocytosis, Lyell syndrome, pancytopenia, Stevens-Johnson syndrome;
• thrombocytopenia, ukusabela anaphylactoid, ukuphazamiseka ukungcamla, iimpawu yelupus, yintloko;
• photosensitivity, paresthesia, hypoesthesia, neuralgia;
• isiyezi, imvakalelo nenzaliseko esiswini, urhudo, ukungabi namdla;
• exacerbation of ukhwekhwe, isicaphucaphu, irhashalala psoriasiform, iintlungu esiswini, myalgia;
• urticaria, arthralgia, irhashalala, pustulosis nolahlo ngokubanzi, ilahleko iinwele, ukwanda enqanda zesibindi;
• ukudinwa, nokuphazamiseka hepatobiliary, nenyongo, ihepatitis.

Analogs neendleko ichiza

Yimalini sisiyobisi "Lamikon"? Ixabiso eli chiza ixhomekeke ukuma kwayo. Ioli zokutshiza zingathengwa ngenxa engange 180-220, kunye tablets - kuba 370-400 engange.

Ke ukuba noogxa, phakathi olusebenzayo ngakumbi uyakwazi aphake imali ezifana "Amorolak" salicylic acid. "Mikoseptin", "Nitrofungin", "Mikolak", "Exoderil".

Izimvo medicament

Ingxelo evela abo basebenzisa iziyobisi "Lamikon" esihle kakhulu. Izigulane ingxelo ukuba ukusebenza kwezonyango kweli chiza kuye kwaphawulwa iintsuku ezimbalwa emva kokuba ukusetyenziswa akhe asebenzayo. Ngokuqhelekileyo, isifo imingxunya iphele ekupheleni kwekhosi unyango.

Kwiingozi ezimasikizi, oogqirha bacebisa ifomu idosi edityanisiwe (umz, amacwecwe aqholiweyo, yokutshiza kunye tablets).

Ukongeza imiyalezo ezintle malunga "Lamikon" ukulungiselela uhlangane kunye nengxelo elibi. Ngokufuthi zinxulunyaniswa kwawo yayo. Nangona kunjalo, iingcali zithi oku kunokwenzeka kuphela xa unyango non-ingqalelo fungi medicament okanye kakubi. Ngoko ke, ngaphambi kokuba isicelo neoli, amacwecwe okanye sokutshiza Kucetyiswa ukuba ubone ugqirha kunye nokuseka i-arhente causative kwezifo ezinzwaneni.