Ichiza "Sporagal": imiyalelo ukusetyenziswa, analogs kunye nohlolo

Indlela ukuthatha ichiza "Sporagal"? Imiyalelo kusetyenziso ichiza ziya kuqwalaselwa ngakumbi. Uya kufunda kwakhona ukuba kukho analogue yale yokulungiselela, wobeka phi kubiza, athi ngaye izigulane, kuba yintoni injongo kubhaliwe ufakwe, njalo-njalo. D.

Form, ukwakheka, ukupakishwa nokubola kweziyobisi

Ukulungiselela "Sporagal" nokumaneka capsule. isithako yayo asebenzayo itraconazole. Kwakhona le medicament liquka polyethylene ethers 20000, sucrose, kunye hydroxypropyl acrylate copolymer.

Malunga iqokobhe, le nto ndiyibhalayo gelatin, titanium dioxide kunye indigotin.

Xa iphakheji ithengiswe amayeza "Sporagal"? Imiyalelo yokusebenzisa esi sixhobo elungiselwe ibhokisi yekhadibhodi. Kwakhona iqulethe gelatin capsule nzima eziluhlaza (e namadyungudyungu), banayo granules ungqukuva umbala omthubi.

Pharmacodynamics medicament

Njani "Sporagal" tablet? Ngokutsho imiyalelo, ichiza yemvelaphi triazole. It anazo umsebenzi phezulu nxamnye zomngundo.

Ichiza inceda ukwehlisa le kuyondelelaniswe yebhayoloji yolo ergosterol, ukunika isiphumo nokubola.

Iingcali zithi itraconazole abangaphangeliyo ukukhula nokukotshwa inani elikhulu kweentlobo ze zomngundo.

Le pharmacokinetics of arhente nokubola

Drug "Sporagal", apho analogue ziya zicaciswe ngakumbi, ngokukhawuleza iye yangena egazini. Bubekwelona nqanaba liphezulu lezinto itraconazole abantu emsebenzini emva kweeyure ezi-3. bioavailability yayo yi-55% (i-obubona owayejongwe njengezingxobo yolwamkelo ngoko nangoko emva kokusetyenziswa a ezityebileyo ophezulu-osidingayo ukutya).

Itraconazole abelwa amalungu ezahlukeneyo kunye nezihlunu umzimba. umxholo lwalo emathanjeni, nezi ntso, nomhlehlo wesibindi, imiphunga, izihlunu skeletal, isisu, udakada namaxesha 3 ngaphezulu egazini.

Medicament umzimba esibindini ukukhulula nobuninzi avela. Noko ke, gidroksiitrakonazol kuphela kuba nefuthe nokubola libizwe.

Malunga nama-34% ukwimo esebenzayo ngesi umchamo, yaye malunga ne-54% ngenxa emathunjini.

Xa abantu umsebenzi kakuhle wesibindi izifo zezintso, kwaye izigulane omzimba bioavailability beziyobisi nga lincitshiswe.

Iimpawu njengezingxobo

Kutheni amisele "Sporagal"? Imiyalelo ithi ukuba ichiza ilungiselelwe ukuba unyango losulelo fungal, apho nomsindo ngamagciwane zovakalelo isiyobisi:

• candidiasis vulvovaginal;
• Ukuphazamiseka ophthalmological kunye dermatological of imvelaphi ezinzwaneni (umz, keratitis fungal, enesitshanguba, pityriasis versicolor);
• candidiasis ngomlomo ;
• onychomycosis, leyo nomsindo dermatophytes okanye igwele;
• mycoses systemic kuquka cryptococcosis (abantu kunye nenkqubo babuthathaka omzimba ngexesha luvo cryptococcosis medicament kuphela xa kungekho iziphumo zonyango kwezinye izinto nokubola), cryptococcal meningitis, aspergillosis systemic kunye candidiasis;
• sporotrichosis, paracoccidioidomycosis, blastomycosis, histoplasmosis, kunye nezinye mycoses kunqabile systemic.

Izimo ukusetyenziswa njengezingxobo

Yintoni Izimo ukuba ukusetyenziswa kweziyobisi "Sporagal" (tablets)? Imiyalelo ithi ukuba ichiza isetyenziswe ku:

• Hypersensitivity ukuba amacandelo eziziiprayimari neziziisekondari ye ichiza
• kunye amayeza afana "Eletriptan" blocker HMG-onx reductase inhibitors (umz: "atorvastatin", "Lovastatin" "simvastatin"), sezakhi yiergot, substrates CYP3A4 (umzekelo, "Cisapride", "bepridil," "pimozide" "Dofetilide", "Astemizole" "quinidine" "mizolastine"), "nisoldipine," "Midazolam", "triazolam".

Kufuneka kuqatshelwe ukuba ukusetyenziswa kwale ichiza contraindicated kubantu abane ventricular kwekhono kunye nokungasebenzi kwentliziyo, ingakumbi umlinganiswa congestive.

Drug "Sporagal": imiyalelo yokusebenzisa

Ngokutsho imiyalelo, ichiza kufuneka kuthathwe ngomlomo kuphela. Le njengezingxobo ziphele nangoko emva kwesidlo (ukuze kuqinisekiswe edalwayo ngcono), lilonke, ngaphandle ukuhlafuna.

Esithathwa yale iyeza kuxhomekeke kuhlobo izifo ezikhoyo:

• Dermatological kunye sisilonda esidumbileyoesingaphakathi ophthalmologic (umz, versicolor pityriasis okanye enesitshanguba) - 200 mg kanye ngosuku iveki yonke.
• amanxeba Keratinized kwesikhumba (izandla neenyawo) - 200 mg kabini ngemini iveki.
• candidiasis Vulvovaginal - 200 mg kabini ngemini kangangeentsuku ezintathu.
• candidiasis Oral - 100 mg kanye ngemini iiveki ezimbini. Xa izigulane AIDS okanye neutropenia, ithamo olwandisiweyo mg 200 kanye ngemini.
• keratitis ezinzwaneni - 200 mg kanye ngemini iiveki ezintathu.
• Onychomycosis, leyo zibangelwa dermatophytes okanye igwele, baphathwa ngokusebenzisa izifundo ngokuphindaphindiweyo. Enye unyango lubandakanya ukuthatha iipilisi ezimbini kabini ngemini iveki. Kuba unyango izitshanguba zezikhonkwane kwi iminwe ikhutshwa phandle izifundo-2 kule unyango, neenyawo zakhe - iikhosi ezi-3. Umda phakathi kwabo bobabini kufuneka iiveki ezi-3. Le nguqu kubonakala emva kokugqitywa khosi (ngokukhula amacwecwe nail).

ukulungiselela ngobungxamo "Sporagal" le isikhonkwane kunye ulusu yenziwa ixesha elingaphezu egazini. Kulo mba, imiphumo kangangoko zonyango izigulane kwiziphumo iiveki kuphela emva ezintathu emva kokugqitywa unyango lwezifo kunye malunga neenyanga ezili-9 emva kokuba unyango lwe onychomycosis.

Iindlela Ukusetyenziswa njengezingxobo for izilonda systemic

Njengokuba amanxeba ezicwangcisiweyo athwale isicelo? "Sporagal" libhekisela kule iidosi zilandelayo:

• Candidiasis - 100-200 mg kanye yonke imihla iiveki 5-30.
• Cryptococcosis ngaphandle meningitis - 200 mg ngosuku iinyanga 3-12. Kunye kabini umthamo meningitis.
• Aspergillosis - 200 mg ngosuku iinyanga 3-5.
• Histoplasmosis - 200 mg kabini ngemini iinyanga ezisibhozo.
• Chromomycosis - 100-200 mg ngosuku iinyanga ezintandathu.
• Sporotrichosis - 100 mg ngosuku iinyanga ezintathu.
• Paracoccidioidomycosis - 100 mg mihla le kangangeenyanga ezintandathu. Kwizigulane AIDS, idosi ukuze kwandiswe.
• Blastomycosis - 100-200 mg kabini ngemini iinyanga ezintandathu.

kwiziphumo ebezingalindelekanga zeyeza

Ingaba kukho naziphi na iziphumo ebezingalindelekanga kubaguli abafumana iziyobisi 'Sporagal "? Iingcali Ukuphonononga ingxelo abasabela ilandelayo:

• neutropenia, thrombocytopenia, leukopenia;
• womchamo ngokuphefumla (phezulu);
• hypertriglyceridemia, hypokalemia, hypocalcemia;
• intloko ebuhlungu, paresthesia, peripheral neuropathy, hypoesthesia, isiyezi;
• ukugula serum, nokudumba angioneurotic, anaphylactic kunye anaphylactoid negazi;
• ukungaboni, diplopia, bakuva ilahleko, ukuduma, ukungaboni;
• ukusilela intliziyo, umlinganiswa ingakumbi congestive;
• dyspnea, nokuthimliswa, sinusitis, nokudumba pulmonary;
• ukugabha, ukuqunjelwa, reactions hepatotoxic, iintlungu esiswini, pancreatitis, isicaphucaphu, dysgeusia, ukuqhina, hepatitis, urhudo, ukuqumba, indawo transaminases isibindi okwethutyana;
• iintlungu amalunga nemisipha;
• irhashalala, photosensitivity, vasculitis leukocytoclastic, alopecia, ityhefu epidermal necrolysis, pruritus, dermatitis exfoliative, irhashalala, etsolo ngokubanzi pustulosis exanthematous, erythema multiforme;
• seTrojan, ngumchamo wokuchama, erectile kwekhono, pollakiuria;
• fever, nokudumba.

izincomo ezithile

Oko umele ukwazi umguli, phambi kokuba ezithatha ichiza "Sporagal"? Iimpendulo ingxelo ukuba ubuncwane bayo esebenzayo kuba nefuthe elibi inotropic.

Nangona ukuthatha le iyeza ndlela ukusilela intliziyo congestive, kunye hepatotoxicity kakhulu.

Xa kuncitshiswa absorbability iziyobisi iasidi kuguga.

Abantu ngaxeshanye nokusebenzisa asidi kufanele ukuba zigcinwe phakathi kwabo neendlela nokulungiselela lokuphumla ochazwe of iiyure ezi-2.

Drug "Sporagal" akukhuthazwa ukuba izigulane abalupheleyo.

Ukuba ngaba uneempawu ze peripheral iyeza neuropathy ukuthatha ukurhoxisa.

Ibele nokukhulelwa

Ngexa lokukhulelwa, amayeza linokwenziwa kuphela mycoses zenkqubo, ezo isoyikiso kubomi sikanina.

Ke ukuba ibele, kweli xesha, "Sporagal" kuvumelekile, kodwa kuphela phantsi ezibonisa engqongqo.

Drug "Sporagal": analogs kunye nexabiso

Ezi zixhobo zilandelayo analogue ezininzi ezaziwayo beziyobisi phantsi ingqalelo, "Itrungar", "Sporaksol", "Orungal", "Eszol" yaye "Funit".

Yimalini sisiyobisi "Sporagal"? Ixabiso le iyeza uyahluka 1100-1200 engange.

Izimvo kulungiselelwa

Ngokutsho ingxelo abo bathabatha ichiza, ukuze kuqwalaselwe ukuba iyasebenza kakhulu esizibonakalisa iintlobo ezahlukeneyo zamangenelela ezinzwaneni. kungenziwa uyazimela imiyalezo ezingalunganga abo bakuphikayo ukuba esi sixhobo sele iindleko eziphezulu. Nangona kunjalo, iingcali zithi ukuba ixabiso eli chiza bugwetyelwe ngokupheleleyo ukusebenza kwayo ngamayeza nokunyanga.

Njengoko ngokuba ezingalunganga kweli chiza, izigulane badla bakhombe ixesha elide yonyango.