Isilwanyana "Revmoxicam": imiyalelo yokusetyenziswa (injections, iipilisi kunye namakhandlela). Iingxoxo kunye nezibuyekezo malunga neziyobisi

Ukunyangwa kwezifo zesistim, ukususwa kwentlungu kunye nokuvuvukala kwamalungu kunye nezihlunu kunokwenzeka ngenxa yezidakamizwa ezingabhubhisiyo, ezibandakanya izilwanyana "I-Revmoxicam." Umyalelo wale arhente uquka inkcazo yokwakhiwa kwazo zonke iifom zeesayithi, iimpawu ze-pharmacodynamic, izibonakaliso nolwazi malunga neempawu zokusetyenziswa.

Inkcazo yokulungiselela

Isalathisi esisisiseko salo mfuziselo ngumzimba we-meloxicam kwiqela le-oxicam, isiseko salo i-enol acid. Esi sichazi sinomphumo okhethiweyo malunga nabalamli beprogram yokuvuvukala, ebalulekileyo ekukhuseleni izitho zokugaya kwiinkqubo ezingafunekiyo.

Kulo myalelo othi "i-Revmoxicam" yokusetyenziswa ukuchaza iifom ezininzi zeelayi ezivumela ukuba ukhethe indlela efanelekileyo yokonyango, ukuqwalasela iimpawu zomzimba kunye nezifo ezihambelana nayo.

Ukulawulwa komlomo, ifomathi ifom ye-meloxicam kwipilisi enye ye-7.5 okanye i-15 mg ifanelekile. Iipilisi eziphezulu ze-dose zisengozini yokuphula isiqingatha, okukuvumela ukuba ulungelelanise iyeza zonyango ngokungabikho kwezipilisi zesilinganiso esingaphantsi. Ifom yefayili ifanelekile kunyango lwangexesha elide.

Ifom ye-injection yi-1% isisombululo senkunkuma esebenzayo, ekhutshwa ngo-1.5 ml kwi-ampoules "Revmoxicam". Imiyalelo malunga nesantya kunye nesantya sokwenza ubeka indawo yokuqala, enokuthi ithathelwe ingqalelo xa ukhetha ifom yefayili.

Ukulawulwa kwamaritha, i-suppositories ene-doloxicam 0.015 g isetyenzisiweyo. Isiseko sesikhanyiso sisona sinezilwanyana zezilwanyana, apho i-active active is distributed.

Ukusetyenziswa kweziyobisi

Isenzo sokulwa nokuvuvukala, i-analgesic kunye ne-antipyretic yesilwanyana "I-Revmoxicam" isekelwe kwikhono lomsebenzi ochanekileyo ukukhetha ukunciphisa iinkqubo ezinxulumene nokuhlanganiswa kwezinto ze-prostaglandin. Zizo ezi zinto zidibanisa iinkqubo zokuvuvukala.

Izilwanyana "I-Revmoxicam" imiyalelo yokusetyenziswa iyayichaza njengesiqhelo esiluxhathelekileyo ngokuthelekiswa nezinye iziyobisi ezingekho-steroidal ezichasayo. Oku kungenxa yokunciphisa ukuphela kwe-enzyme cyclooxygenase hlobo 2, okubangelwa ukuveliswa kwe-prostaglandin kunye ne-prostacyclin izinto ezinobangela wokuvuvukala. Isilwanyana sinomphumo omncinci kumhlobo we-cyclooxygenase, oko kutheni i-prostaglandins ye-gastroprotective kunye ne-thromboxanes ziveliswa kwisixa esifanelekileyo kwaye isebenza njengendlela yokukhusela inkqubo yokugaya ukuphuhliswa kweempendulo ezingathandekiyo.

Isithako esisebenzayo sokulungiselela "i-Revmoxicam" (i-ampoules) ichaza umyalelo wesicelo njengenxalenye engaguquli iiseli zezicubu ze- cartilaginous kwaye ayithinteli ukuveliswa kweproteoglycans, ebonwa xa iphathwa ngayo, umzekelo, i-indomethacin.

Amayeza ayitshintshi i-platelet aggregation kunye nobude begazi, njengokuba kwenzeka nge-diclofenac kunye ne-ibuprofen.

Analogues

Kwiimakethe zonyango, kukho inani lamachiza aguqukayo, afana nokusebenza kunye nesilwanyana "Revmoxicam". Ukufundiswa kwezifaniso kubonwa njengama-synonyms, aphinda aphinde azaliswe ngendlela yokulungiselela yaseJamani "Movalis" yenkampani ethi "Boehringer Ingelheim" kwifom ethile yokulinganisa.

Uluhlu lweemithi olusekelwe kwi-meloxicam lwenza ukuba izigulane ziphathwe njenge-European (Meloksikam-Teva, Mirlox, Meloks), kunye neyeza zonyango ezihluka kakhulu kwixabiso. Phakathi kwamachiza okuveliswa kwemveliso yaseRashiya, kukho "uMovasin", "Lem", "Meloksikam", "Arthrozam", "Ameloteks."

Iindidi ezahlukahlukeneyo zamachiza-izivumelaniso zezityalo ezahlukeneyo zithetha ngokusetyenziswa ngokubanzi kweyeza ezisekelwe kwi-meloxicam.

Kutheni usebenzise

Ukulungiselela imiyalelo ye-"Revmoxicam" yokusetyenziswa kweenjini, iipilisi kunye ne-suppositories kunconywa ukuba unyango lweentlungu, ukuvuvukala kunye neenkqubo ezixhatshazayo kwinkqubo ye-musculoskeletal, efana ne-arthrosis, i-rheumatoid arthritis, i-osteoarthritis, i-spondylitis e-ankylosing.

Ngokwendlela yokusebenza, le nkonzo iyakulungelelanisa iinkqubo ezahlukeneyo ezivuthayo emzimbeni womntu. Ayikho yonke imiqondiso engabonakaliyo ibandakanya imithi ethi "Revmoxicam" (ikhandlela). Kwizintsholongwane zonyango isetyenziswa ngokubanzi kunyango lweenkqubo zokuvuvukala kwamalungu omzimba wesini, umzekelo, ii-ovaries. Nangona kunjalo, ukuqeshwa okunjalo kunokumiselwa kuphela ngudokotela oya kwintlanganiso, oza kuseka i-dosing kunye nobude bonyango.

Ukusetyenziswa kwamacwecwe

Ifayili efomathiweyo ifakwe ekulawuleni komlomo. Ukunyuselwa kwe-meloxicam kwindlela yokugaya ihamba ngokukhawuleza kwaye i-90%. Ukutya akuphazamisi ukungena kwe-meloxicam ngokusebenzisa i-mucosa yamathumbu.

Thatha iyeza "I-Revmoxicam" (amacwecwe), umyalelo ucebisa kunye nokutya ukunciphisa umngcipheko wokuphuhlisa ukungafuneki kwinkqubo yokutya. Ithebhulethi kufuneka igxinwe ngokupheleleyo, ungayiphuli okanye uyichoboze, yiphuza kakhulu amanzi. Ubungakanani bonyango kunye nokulingana kwesilwanyana kuxhomekeke kwisibandezelo sesi sifo kwaye kugqitywe ngugqirha.

Unyango lwe-osteoarthritis kubantu abadala kunye nabaselula abasusela kwiminyaka eyi-15 ubudala baqhutyelwa nge dose yemihla ngemihla ye-7.5 mg. Ukuba kuyimfuneko, ugqirha unokuphinda kabini umthamo wemihla ngemihla.

Unyango lwe-arthritis ye-rheumatoid kunye ne-spondylitis engabonakaliyo kubantu abadala kunye nabaselula abasusela kwiminyaka eyi-15 yenziwa nge-dose yemihla ngemihla ye-15 mg. Isisombululo sincitshiswe sibe ngu-7.5 mg kuphela emva kokufumana ama-dynamics ayenzayo ukusuka kwiyeza eliphezulu.
Ukuba kukho imfuneko yokuphuhliswa kweempembelelo ezimbi, izigulane zimiselwe ukuthatha isiza kwi-dose eyodwa ye-7.5 mg.

Ukusetyenziswa kweenjini

Ukwenza isantya esiphuthumayo, isilwanyana "Revmoxicam" (iinjenge) sisetyenzisiweyo, imiyalelo yokusetyenziswa ichaza isilathisi se-parenteral engumjovo weesram. Esi sicelo sichazwe kubantu abanezifo zendlela yokugaya. Oku kubangelwa kukuba isisu okanye amathumbu awonakaliswe ngamacwecwe eziyobisi "Revmoxicam". Izikhokelo zokusetyenziswa kwezibhengezo zicebisa ukuba zingene kwindawo yecala eliphezulu elingasemva kweentsimbi, zingene kwi-muscle.

Ixesha leyeza unyango kunye nesilinganisi seyeza lixhomekeke kwisibandezelo sesi sifo kwaye senziwa ngumgqirha.

Abantu abadala kunye nabaselula abasusela kwiminyaka eyi-15 ubudala babeka umthamo wezilwanyana "I-Revmoxicam" myalelo wokusetyenziswa, iilenki zenziwa kanye ngosuku. Ngokuqhelekileyo, ukusuka kwi-0.75 ukuya kwi-1.5 ml yesisombululo se-meloxicam. Isilwanyana "I-Revmoxicam" ngesimo senjojo singasetyenziswanga ngaphezu kweentsuku ezingama-5, kwaye utshintshele kwiifom zefayile zeli cilisi.

Emva kokulawulwa kweziyobisi, i-substance yayo esebenzayo ithatha i-100% kwi-systemic bloodstream, ebonisa ukuhlaselwa kwayo.

Akubona zonke izigulane ezivunyelwe ukusetyenziswa kwamachiza aphezulu "I-Revmoxicam", umyalelo wokusetyenziswa kweejoyi kubantu abanomdla kunye nokungafihleki, ukukhuthaza ukuqhuba nge dose 7.5 mg meloxicam. Ngelo xesha, iziboniso zala malungu mazibekwe iliso ukwenzela ukuthintela ukungonakaliswa kwimeko.

Ukuba usebenzisa iindlela ezininzi zezilwanyana "I-Revmoxicam" ngexesha elifanayo, kucetyiswa ukudibanisa ii-injections, iipilisi okanye i-suppositories ukwenzela ukuba idosi ecebisiweyo yokubanjwa kwansuku zonke ayikho phezulu.

Imiyalelo yokusetyenziswa kwamakhandlela

Amachiza angasetyenziswa ngokusemthethweni ngokufaka i-suppository kwi-rectum ukuze ilandelelanise ngakumbi into eyenziwa yimithambo yegazi kwi-rectum kunye nokungena kwe-meloxicam kwigazi.

Ukuze kuphunyezwe le nkqubo, kufuneka ulungele ukulungiselela ngokuqhuba ukucocwa kwezempilo. Iimakhandlela "I-Revmoxicam" yokufundisa isetyenziselwa ukukhupha kunye nokujova izandla ngezandla ezihlambulukileyo, ukuze ungasifaki ukusuleleka kwintsholongwane yomntu.

Amakhandlela alo lungiso ayenziwe ngamafutha aqinileyo, atyhidika ngokukhawuleza ezandleni, ngoko ukuqaliswa kwe-suppository emva kokuba uvule ipakethe yokuqala kufuneka ihambe ngokukhawuleza. Ithuba lokusetyenziswa kunye neli dose lixhomekeke kuhlobo lwesifo kunye nesantya sobunzima, kodwa nangona kunjalo, yonke imimiselo imiselwe ngugqirha.

Isicelo esifanelekileyo se-meloxicam sivumela ukuba singene kwi-systemic bloodstream, ngokufumaneka kwe-90%. Isiqulatho esisisigxina se-plasma yegazi senziwa emva kweentsuku ezingama-5 ukususela ekuqaleni kweyeza.

Kubantu abadala kunye nabaselula abasusela kwiminyaka eyi-15 ye-"Revmoxicam" amabhandlela, imiyalelo yokusetyenziswa imisele ukuba ingasebenzisi ngaphezu kwe-1 ifowuni enye ngosuku.
Isixa esiphezulu se-meloxicam ngosuku kufuneka sibe malunga ne-15 mg, ehambelana ne-1 suppository.

Ngokwemiyalelo yokusetyenziswa, ukulawulwa kwemirhoxiso yeyeza kungabi ngaphezu kweveki, kwaye unyango olongezelelweyo kufuneka lugqithiselwe ekusebenziseni iifom zefriji "I-Revmoxicam."

Xa ungeke ukwazi ukusebenzisa iyeza

Akunakwenzeka ukuba kusetyenziswe imveliso "I-Revmoxicam", umyalelo wokusetyenziswa uquka uluhlu lweengqinisiso, apho le nyeza ingasetyenziswanga.

1. Ngenxa yokwanda komntu ngamnye kwi-oxycam nakwezinye iziyobisi ezingekho-steroidal ezichasayo, le nkunkuma ikhanseliwe.
2. Musa ukusebenzisa ifomethi yezilwanyana kwizigulane ezinobunzima bokutywala i-glucose kunye ne-galactose, ngeempawu zokuntuleka kwe-lactase nokunyamezela komnye kwii-molecule ze-galactose.
3. Unyango kunye neyeza liphikisana nabantu abanesifo sesilonda esiswini esiswini kunye ne-duodenum, abanezifo zesibindi, kunye nesifo senhliziyo kunye nokungaphumeleli kwezintso kwifomu enzima, kubantu abafumana i- coronary artery bypass grafting.
4. Ungasebenzisi izilwanyana kwizigulane ezisemngciphekweni omkhulu wokugaya igazi, ingakumbi ukuba kukho i-cerebrovascular okanye ibonakalisa ukuphuma kwegazi.
5. Isilwanyana "I-Revmoxicam" ngendlela yeebhandlela ayisetyenziswanga kwizigulane ezinezifo ezixhamlayo. Ukutshatyalaliswa kwakhona kwindlela yokuvuvukala ye-rectum.
6. Abafazi abakhulelweyo nabancelisayo, abantwana abaneminyaka engaphantsi kweminyaka eyi-15 ubudala, le nkunkuma ayimiselwe ngenxa yesiphumo sayo esinobungozi kumzimba okhulayo.
7. Isilwanyana "i-Revmoxicam", iilenki, umyalelo uvimbela ukusebenzisa i-intravenous, eyamkelekileyo kuphela yejoza ye-intramuscular in muscle glutal.

Ngokulumkisa unyule izilwanyana kwizigulane ezine-asthma, i-cirrhosis, i-cirrhosis, i-dishydration, izifo ze-urinary system, ukukhubazeka kwentliziyo, ukuhla kwegazi.

Izigulane ezisebekhulile, abantu abanomzimba obuthathaka okanye abafumana unyango lwe-anticoagulant kufuneka bathathe eli liyeza phantsi kweliso logqirha.

Unonophelo olukhethekileyo ludinga unyango lwabantu abaneziyobisi abaye banesilonda esiswini esiswini kunye ne-duodenum kunye nezinye izifo zendlela yokugaya ukutya ngexesha elidlulileyo.

Ukudibanisa namanye amayeza

Ukudibana kunye nezinye iziyobisi kunye neziyobisi "I-Revmoxicam" inokuphucula okanye iyanciphise ukusebenza kwayo, kubangele ukuphendula okungathandekiyo.

• Ukusetyenziswa ngokudibeneyo kwemilo ye-meloxicam kunye neyodwa engekho i-narcotic i-analgesic imithi ibangela umngcipheko ophezulu wezilonda kwizilwanyana ezinobungozi okanye kuphuma igazi.
• Akukhuthazwa ukudibanisa ukulungiselela "i-Revmoxicam" ngamachiza anticoagulant kunye nama-thrombolytic anika i-antiaggregation yeeseli zegazi.
• Ukwamkela ngokufanayo i-meloxicam kunye ne-diuretics malunga nemvelaphi yokudambisa amanzi emzimbeni kunokubangela ukuhluleka komzimba kubantu abanjalo. Ukuba ukususela kwamukelwayo akunakwenzeka ukunqanda, ukuhlolwa rhoqo kwentsholongwane kuyimfuneko .
• Isicelo esisodwa singabangela ukwehla kwempembelelo yokwelapha kwezilwanyana zokukhulelwa kwe-intrauterine, beta-blockers, vasodilating, izidakamizwa ze-diuretic kunye namachiza abandakanyekayo kwi-inhibition ye-enzyme yokuguqula i-angiotensin.
• Ngokudibanisa ne-methotrexate, isilwanyana "i-Revmoxicam" sinako ukwandisa umonakalo onobungozi kwiiseli zegazi, kwaye ukuphathwa ngexesha elilodwa kunye ne-cyclosporine kubangela umphumo ongalunganga emsebenzini wezintso. Ukuba kukho imfuno yolu ngqamaniso, ngoko kubeka iliso kwimeko yegazi kwimiba ye-periphery kunye nokusebenza kwengqondo kuyimfuneko.
• Isenzo sonyango sijoliswe ekunyuseni i-i-ion ions kwi-plasma yegazi. Ukudibanisa kwe-colestyramine kunye nokulungiselela "i-Revmoxicam" kukhokelela ekunciphiseni ngexesha lokuxhoma kwezinto ezisetyenziswayo.
• Isenzo sale nkunkuma engeyiyo-steroidal echasayo ijolise ekutshintsheni ukusebenza kwimisebenzi yezilwanyana zonyango, kunye nezo zine-insulin. Kuba izigulane ezinezinga eliphezulu lokushukela kwegazi, ukuthatha isixhobo "I-Revmoxicam" kufuna ukulawulwa kwe-glucose into eplasma yegazi ukwenzela ukulawula umthamo wonyango lwe-hypoglycemic.

Uphononongo malunga neziyobisi

Njengoko kubonakala, uluhlu lwesilwanyana "i-Revmoxicam" luhluke, imiyalelo ayichazi imiyalelo, kodwa ichaza yonke imiphumo engathandekiyo ekusebenziseni le ngcebiso, konke ukuchasana kunye nokusebenzisana. Ingcaciso enjalo ayithethi ukuba zonke iimpendulo ezimbi zimele zenzeke emva kokuthatha amachiza asekelwe kwi-meloxicam. Unyango lunokuthi luqhutywe ngaphandle kwemiphumo engathandekiyo emzimbeni, kwaye umphumo wonyango uya kubonakala. Umzimba ngamnye uqobo kwaye usebenza ngokungafaniyo kwizinto ezahlukeneyo.

Njengoko sele kuphawulwe, akukho zonke izibonakaliso zokusetyenziswa ezichazwe kwimimiselo, kodwa kuphela ezo eziphathelele unyango lwe-rheumatic system of musculoskelet system.

Ukuba isicatshulwa esichasayo, isilwanyana "Revmoxicam" sifumane isicelo esiphezulu sokonyangwa kwezinto ezahlukileyo, njengengxenye yonyango oluyinkimbinkimbi yokuvuvukala kwi-prostatitis engapheliyo, iinkqubo ezivuthayo kwiindawo zentsholongwane.

Ukukhawuleza ukususa isifo sesifo, ndincoma ukujova iijojo nge-"Revmoxicam" ukulungiselela. Iingxelo malunga nokusebenza kwezijokelelo ezizwakalayo.

Esinye isigulane ngokukhawuleza siba lula, intlungu ibuyele, esinye isiyobisi asihambisani, kwaye kufuneka ufune indawo.

Ukunyanga izimo ze-rheumatic, amaphilisi e-meloxicam asetyenziswa, angathathwa ixesha elide, nangona kunjalo, unyango olunjalo lunokubangela ukuphazamiseka kokugaya abantu abaninzi, okufuna ukupheliswa kweyeza.

Kukho ukuhlaziywa okulungileyo kwonyango edibeneyo ye-adnexitis, xa idibaniswa neziyobisi ezichasayo ezikhuselweyo, "i-Revmoxicam" i-suppositories isetyenzisiweyo.