"Metformin" iziyobisi. Ncomo. abstract

Drug "Metformin" ibhekisela zomlomo arhente hypoglycemic iqela biguanide. Xa usebenzisa izigulane kunye seswekile kweziyobisi lihlisa amanqanaba iswekile yegazi ngokuthi ziyibuyisela gluconeogenesis esibindini, kwakunye nasekunciphiseni kukufakwa wayo ukusuka kwinkqubo yokwetyisa. Ngenxa yokwanda uvakalelo izicwili insulin kwandisa (iswekile) ukusetyenziswa kwayo. Medicament "Metformin" (izimvo kwiingcaphephe kule show) lineziphumo kwi lipid ukutya. Ichiza inceda ukwehlisa triglycerides, LDL cholesterol in serum. Ichiza kunciphisa (omeleza) ukwanda ubunzima bomzimba. Xa zingene kukufakwa kuthetha zomyalelo 48-52%. Ukusetyenziswa ngaxeshanye ukufakwa ukutya lifinyele. Le xi eliphezulu wafikelela ngeeyure 2-3. Ichiza zingazange ubotshiwe kwiiproteni plasma, ukuba umzimba ukuya isidanga engaphantsi.

"Metformin" lithetha. isicelo

Ukumisela amayeza e uhlobo yesibini seswekile (diabetes) e abadala (ingakumbi ukutyeba) xa kungekho kwesiphumo umthambo, unyango yokudla. Medicament "Metformin" (reviews of oogqirha zingqinele oku) ingasetyenziswa zombini njenge monotherapy kwaye njengenxalenye arhente yomlomo hypoglycemic okanye insulin. Ichiza kwakhona ilawulwa abantwana ukusuka kwiminyaka elishumi kunye type 2 diabetes njenge monotherapy okanye njengenxalenye nempembelelo ezihlanganisiweyo.

Izimo

Medicament "Metformin" (reviews of oogqirha zilumkisa ngale) kufuneka ukuba athathwe ukuba diabetic isiqaqa, precoma, ketoacidosis, hypersensitivity. Izimo ziquka isimo nokoyika ngemvelo, aqalayo kunye namathuba ingenzeka le kwekhono kwezintso. iziyobisi okunikezelwe kwiNtetho kaMongameli hypoxia, ngexesha emzimbeni, ngezifo yokuphefumla, ukwenzakala kwizintso zohlobo ezasulelayo, nokudumba, ukothuka, ukusilela isibindi, Ityhefu utywala etsolo, lactic acidosis, imbali ngokunjalo. Akukhuthazwa kweziyobisi bephethwe ngokwezonyango eyodwa ezimbi oyingozi okanye engapheliyo ukuba kungabangela ijwabu hypoxia. Iimeko ezinjalo ziquka ukuhlasela etsolo intliziyo, ezokuphefumla, sisifo sentliziyo kunye nabanye. Hayi prescribers abangaphantsi kweminyaka engama elishumi, ngokuxhomekeke ukutya yancitshiswa-osidingayo. Isilumkiso wabonisa xa kuwaphatha (iminyaka engama-60) abadala ezinolwazi izinto ezidibene amandla omzimba.

imiphumela emibi

Ichiza "Metformin" (izimvo kwiingcaphephe kule show) kungabangela ukonakala wokutya, ukugabha, isicaphucaphu, ukuphazamiseka incasa, urhudo, irhashalala, erythema, kunye nezinye ulusu komzimba. Ukuphucula tolerability zesisu Kucetyiswa ukuba ukwandisa idosi kancinci. Ngenxa unyango waphawula iintlungu esiswini, hepatitis, ukuphazamiseka komsebenzi zesibindi. Njengomgaqo, amatyala ekubhekiswe imiphumela emibi amachiza. Ngokuchasene imvelaphi lokusetyenziswa elide ukuze aphuhlise vitamin kusekho B12, folic acid.