Hormone estradiol: izinga kumabhinqa. Estradiol: izinga lokukhulelwa

Umzimba womntu - kwinkqubo, ukusebenza kunokuchaphazela kakhulu iihomoni. Ezi izinto eziphilayo esebenzayo eziveliswa iiseli kwamadlala yonyango. Bengena kwemithambo yegazi kuchaphazela nethe kunye nomsebenzi nezibilini. Engxakini ezi zihlanganisi ukuze ukuphazamisa ukusebenza kweenkqubo ezahlukeneyo zomzimba. Eyona nto ibalulekileyo kakhulu umsebenzi enzala ingqalelo besini hormone estradiol. UNorma nakumabhinqa eli isixhobo kuqinisekisa kuphela lokwanda ophile, kodwa iimilo inkangeleko yazo.

Yintoni estradiol

Le yenye yezinto ezibalulekileyo iihomoni, lalo kwiqela estrogen. Phantsi sakhe, abafazi wabumba nkqubo lokuzala kunye namaziko zangaphakathi ukuba banoxanduva umsebenzi okuzala. Ngaphandle kwale nto esebenzayo onoxanduva yakhiwe ahanjiswa lwamanani kunye besini enobulungisa, ukukhula nencum, ulawula isimemezelo ngamanqatha ongama kwi esisu kunye kwamathanga. Hormone iphembelela inqanaba inkanuko yesini kunye ladies sawo, ulawula sexesheni.

Yintoni iimpawu

Hormone estradiol kwabasetyhini unako ukuphucula kwegazi liya isibeleko, kuba nempembelelo entle imeko iimpahla. into esebenzayo anazo:

• ukusebenza steroid.
• It ibalekisa inkqubo egg ekukhuleni.
• Kwandisa yokucolwa in kwezihlunu ithambo.
• Sodium namanzi yokugcina emzimbeni.
• Kwehlisa cholesterol.
• It kwandisa ekunqandeni igazi.

Estradiol ikhuthaza ukukhululwa neurotransmitters ephungula ucaphuka kunye nokuthintela overexcitement luvo. imeko ebalaseleyo eluswini, akukho Undintshwenyisile, okhanyisele emehlweni, lokuphathana nehlombe, ukunyamezela ngokwasemzimbeni - zonke ezi mpawu ukuqinisekisa inqanaba eqhelekileyo estradiol egazini. Izinga eliphezulu hormone elifana neli phakathi iiyure 15-18., Ke incinane ukukhululwa yayo kwenzeka ngo-24 h. To 2 hr. Kusa.

KwiSithethe hormone emzimbeni nemazi

Uyondelelwano lwee- estradiol egazini uyakwazi iyahluka ngokuxhomekeke isimo somzimba umfazi sithuba somjikelo sexesheni. Xa amanqanaba ephilayo ladies sex ihomoni esempilweni ukuba kwehliswe ngexesha lesigaba follicular komjikelo. Bamalunga nama-3-6 iintsuku phambi kokuba ukwandisa yebhinqa ihomoni (LH) iqala ukunyusa kunye amanqanaba estradiol, apho ukunyuka rate kakhulu kwaye ufikelela ubuninzi iyure enye phambi kokuba kwincopho LH.

kwiintsuku nje ezimbalwa emva kokuba xi ubuninzi luteinizing hormone uqalisa ukunciphisa kakhulu Isalathisi estradiol, ngoko liphuma kwakhona kancinci. Ayafika enye ubuninzi ngomhla-9 emva ovulation. Kodwa ukuba ukukhulelwa ayikhange yenzeke, inqanaba into esebenzayo iqala ukwehla nokufikelela imithetho.

iziphumo laboratory

Kubaluleke kakhulu ukuba zonke intombazana ukuqhuba inqanaba uphando ngamaxesha le iihomoni eziphambili. Iziganeko zezifo ezininzi, ukuphazamiseka amalungu angaphakathi kunye ukungasebenzi kakuhle kwenkqubo lokuzala - zonke ezi ngxaki kunokubangela aphezulu okanye asezantsi hormone estradiol. Ummiselo for abafazi lungazaliyo umntwana:

• Isigaba Follicular - iirhafu ziqala ukusuka ku-57 ukuya 227 pmol / L kwi plasma.
• peak Preovulatory - kukuba ukusuka 127 ukuya 476 pmol / l.
• Isigaba Luteal - izinga ukusuka 77 ukuya 227 pmol / l.

Kufuneka kuqatshelwe ukuba amabhinqa (in exesheni), la manani asezantsi kakhulu.

Eyona hormone lokukhulelwa

Njengoko oogqirha, akunakwenzeka ukuthwala umntwana kwi incitshiswe kwinqanaba estradiol. Eneneni, kweli xesha, hormone kufuneka abe khona emzimbeni kwimali eliphezulu: kuxhomekeke kwi indlela efanelekileyo ngumkhaya, inegalelo kuphuhliso nokukhula wesibeleko, yaye normalizes kwegazi kwi amalungu zangasese. Ukongeza, nguye onoxanduva eqhelekileyo igazi ekunqandeni ngexesha lokuzalwa komntwana, ukubonelela ingozi encinci ukopha. Kodwa amanqanaba asezantsi kwezinto zebhayoloji kungakhokelela kwesisu, ingakumbi ekukhulelweni ekuqaleni. Ngoko ke, estradiol hormone - ukukhulelwa yinto:

• kwiiveki 3-6 - 0.5-4.0.
• 7-8 - 4.0-7.5.
• 9-10 - 7.5-8.5.
• 11-12 - 8,5-10,9.
• 13-14 - 10,5-12,0.
• 15-16 - 12,0-21,5.
• 17-18 - 21,5-29,0.
• 19-20 - 29,0-37,0.
• 21-22 - 37.0-38.0.
• 23-24 - 38,0-42,0.
• 25-26 - 42,0-45,0.
• 27-28 - 45,0-50,0.
• 29-30 - 50,0-52,0.
• 31-32 - 52,0-55,0.
• 33-34 - 55,0-57,2.
• 35-36 - 57,5-59,0.
• 37-38 - 59,0-61,0.
• 39-41 - 61,0-66,0.

Oogqirha Siyaleza esweni amanqanaba hormone ngexesha lokukhulelwa rhoqo.

Indlela ukuba bahlolelwe

Njengoko amagqirha zithi into yesibini iqela elibalulekileyo estrogen kwabasetyhini indawo hormone estradiol. UNorma ukukhulelwa osisiqu kufuneka ifakwe ngokuthobela le migaqo:

• state-avareji ngokweemvakalelo - akuvumelekanga ukuba uhlaziye kwimo overstrain luvo okanye hyperexcitability.
• Aninako ukusela utywala kunye umsi.
• Ngenye imini phambi isifundo ukuphelisa uxinzelelo emzimbeni kunye neentlobano zesini.
• Wayikrazula uhlalutyo ungatyanga kusasa phambi kokuba adle.

Ngokulandela le mithetho, ungafumana iziphumo zovavanyo ezichanekileyo, kodwa ukuba zange ukuthobela okanye uthathe nawaphi na amayeza, kufuneka wazise ugqirha.

Yintoni ebonisa inqanaba hormone egazini

Kubalulekile ukwazi ukuba kutheni into esebenzayo kwandisa eyavela egazini. La manani zibonisa ubukho zinto zilandelayo:

• Ukuphikelela kwentswela-le follicle.
• Cysts umlinganiswa isizalo endometrioid.
• yamathumba ezahlukeneyo ovarian.
• Ukuqina.
• Ukwamkela iziyobisi phenytoin, ketoconazole, mifepristone, nafarelin, estrogen.

Estradiol liphantsi kunesiqhelo kwabasetyhini kunokubangelwa zizinto ezifana:

• Okhawulezileyo.
• ezidalwa yebhinqa.
• Giperprolaktinimiya.
• Insufficiency kwesigaba luteal.
• Virilnoe syndrome.
• syndrome Turner lowo.
• ukukrala Chronic of amalungu obuni zangaphakathi.
• Intsongelo of kwesisu.
• Ukutshaya abafazi abakhulelweyo.

Kwezinye iimeko, xi hormone liyancipha ngenxa yokwanda umsebenzi ngokwasemzimbeni, ngokukhawuleza ukwehla kobunzima, xa kungekho kwamafutha ekutyeni, imifino. Iimpawu yamanqanaba asezantsi olwazi estradiol wesikhumba ezomileyo, umjikelezo sexesheni, okanye ukungabikho kwayo, kudala kumitha, ukuncitshiswa ibele. Kuyinto ke ngoko ebalulekileyo xa uceba ukukhulelwa iliso igazi hormone estradiol. UNorma amabhinqa weli iya kuqinisekisa nje kuphela ekumitheni ekhuselekileyo, kodwa kwandisa ngokubonakalayo amathuba okuba akhulelwe ngempumelelo kunye nokunikezelwa ngenxa kamama elizayo.

amayeza

Ukuba uphando olubekwe kumanqanaba asezantsi estradiol, ugqirha ukubekwa amayeza ziqulathe le nto. Abazange kuphela ukunceda ukubuyisela umjikelo oluqhelekileyo sexesheni, kodwa eboniswe amaqanda polycystic, lobufazi, nenzalo, ubuthathaka ngenxa ekuzalweni, xa ukukhulelwa emva elide, kuba zisanyisa kwezithandani emva kokuzalwa, hypertrichosis xa virial. imithi ezinjalo ziveliswa ngeendlela ezahlukeneyo: tablets, ijel, transdermal, izisombululo intramuscular, isipreyi ngeempumlo, transdermal iinkqubo zonyango. Khumbula ukuba, kuphela ugqirha angakunika unyango olufanelekileyo! Kuxhomekeka ukusetyenziswa ngabanye:

• "Estrofem" iipilisi.
• "Proginova" gel.
• Inaliti "Estraderm TTS 25".
• "Estradiol" gel.

Emva kokuba uvavanyo yamanina unikwe unyango, it ihlala ixesha elide. unyango olunjalo ukuphucula hormone estradiol yomzimba. UNorma amabhinqa weli lubalulekile ukuze eqhelekileyo yokusebenza kwenkqubo lokuzala kunye nokukhulelwa.