Ichiza "Avastin": baqinisekiswa

Ichiza "Avastin" sisixhobo mihla nomhlaza. Isetyenziswa ukunyanga iintlobo zomhlaza, kuyanceda ukucinezela ukubonakala Ukudlulela, ukunciphisa microvascular permeability uvingce ukuqhubela phambili kwesifo. Kule mihla, abantu abaninzi, izigulane ezinomhlaza babacukucezela unyango ngamachiza "Avastin". Reviews ngayo zahlukile. Kukho imizekelo ezithile malunga HIV unyango lwezifo kunye nohlaziyo ezininzi malunga ngamampunge ichiza. Abanye abantu "Avastin" ebangela nemiphumela emibi kakhulu.

isakhiwo

Lezithako "Avastin" engundoqo esebenzayo - bevacizumab. Ichiza wathengisa njenge mxube, nto leyo yenziweyo isisombululo ibe nokubandakanywa efakwa. "Avastin" into enemibala okanye umbala ukukhanya omdaka. Sales zingafunyanwa iintlobo ezimbini "Avastin" ezahlukeneyo kwi uyondelelwano lwee- eyona nto engundoqo esebenzayo: 100 ml mg / 4 kunye 400 mg / ml-16.

ubungqina

Ichiza iboniswe ngenxa zifo zilandelayo:

• umhlaza webele kwi zigaba yamva xa Ukudlulela iqala.
• cell carcinoma kwezintso.
• unomhlaza wamathumbu.
• umhlaza cell wemiphunga Non-amancinane.
• Glioblastoma (njalo).
• -Ezinxulumene Age yamehlo macular (AMD), ithumba indawo okolomakulyarnoy, rinopatiya seswekile.
• Okwangoku luya lusiba nochatha ukusetyenziswa "Avastin" zamehlo. Ukuphonononga ukuba unyango lwezifo iliso ezinxulumene nokukhula lwezidumbu nemithambo, eyakhayo.

Izimo

Ngokuhambelana kunye imiyalelo ichiza akunakusetyenziswa "Avastin" kwiimeko ezinjalo:

• Phambi yokwanda Uvakalelo umguli njengenye yeekhomponenti eziqulethwe ekulungiseleleni.
• Ngethuba lokukhulelwa nokuncancisa. Studies kwi isiphumo "Avastin" kolu didi izigulane ziye zaqhutywa. Yinto eyaziwayo ukuba iziyobisi iziyobisi kusichukumisa ngumkhaya, nto leyo enokukhokelela kwezithandani of angiogenesis olungekazalwa. Abasetyhini abo yokuzala, kucetyiswa ukuba usebenzise kukhulelwa enokuthenjwa iinyanga ubuncinane ezintandathu emva kokuba unyango kunye eli chiza. Ukongeza, ukuba kuyimfuneko, "unyango Avastin" ekucetyiswa ukuyekwa ibele, njengoko kunokubangela ukukhula nkene nophuhliso usana. Noko ke, le uphando bokuba.
• yobudala yabantwana.
• Xa ukusilela kwezintso nesibindi. Studies isiphumo ichiza kolu didi izigulane lwenziwa.

ukusabela ezingalunganga

Ezinye izigulane wehlelwa ziziphumo ebezingalindelekanga xa unikwe unyango "Avastin". Ukuphonononga lubonisa ukuba impendulo ichiza kuba kubi kakhulu:

• Perforation ye phecana zesisu.
• Ukopha, xa Vol. H. Lung.
• thromboembolism wegazi.

Kwakhona iquka ezinye ziziphumo ebezingalindelekanga kwi ichiza "Avastin" umyalelo manual. Izimvo kubo ingabonwa kaninzi. Zezi:

• Ukunyuka uxinzelelo lwegazi.
• Ukuvela intlungu ukudumba esiswini.
• A ukuziva ubuthathaka.
• Asthenia.
• ukusilela Heart.
• Neutropenia, leukopenia, igazi.
• Zingakwenza ukuba ube nesicefucefu, ukugabha, stomatitis.
• Uphuhliso anorexia.
• ukopha efakwa.
• Hypoxia.
• ileus.
• Nokuthimliswa, dyspnea.
• Isikhumba uba umbala ezomileyo kunye notshintsho.
• ukufiphala kwamehlo.
• Ubuthathaka imisipha.
• Uphuhliso zizifo womchamo.
• lobushushu emzimbeni kwenyusa.
• Iintlungu, ukuba eyendawo ezahlukeneyo.
• Nokudumba - usulelo umzimba.
• inqanaba mpilo lifinyele.

oyi

Xa ukuphatha iziyobisi "Avastin" kwaye ekupheleni isicelo sayo ezinye iinyanga ezintandathu kucetyiswa ukuba ukuyisebenzisa. Sebenzisa beziyobisi, kwakunye nokumisela umlinganiselo walo angenza liyincutshe onamava kuphela. Ichiza asihambelani sisombululo dextrose.

isicelo

Ukulungiselela "Avastin" yaziswa kuphela / ithontsi, ulawulo / jet akuvumelekanga ngokungqongqo. Oyidlayo ixhomekeka kuhlobo sifo. Solution "Avastin" kufuneka kwenziwe kuphela phantsi kweemeko inzalo ubuninzi. Umthamo ofunekayo "Avastin" yaze yangxenga ifuthe lomanyano ku 100 ml sodium chloride 0.9% isisombululo (kwizigulane kunye ubunzima enkulu ewonke kufuneka zifike 200-250 ml).

Nokuhlanganiswa yokuqala "Avastin" kuhlala imizuzu 90. Faka imveliso lulandelayo emva ichemotherapy. Ukuba emva kokuba ulawulo kuqala, ixesha ukumnika yesibini zingenziwa imizuzu engama-60, yaye okwesithathu - imizuzu engama-30. Ukuba ngaba uneziphumo ebezingalindelekanga, abasunguli akukhuthazwa ukuba ukunciphisa ithamo ichiza. Ukuba ufuna njalo, ngoko ke kufuneka uyeke unyango "Avastin 'ngexesha elithile okanye ayeke akatsho.

libanda

Xa kunikwa "Avastin" kwi idosi iphezulu (20 mg / kg ubunzima bomzimba, umzimba 2 iiveki interval) kungenzeka iimpawu izigulana libanda. Kwezinye izigulane bekukho maxa migraine kakhulu. Ngaba ziya iimpawu yeziphumo ebezingalindelekanga.

iimeko yokugcina

lobushushu yokugcina ichiza degrees 2-8 Celsius. ezikhabhathini - ukuya kwiiyure ezingama-24. "Avastin" Awukwazi ukumisa okanye uyihlukuhle. Isisombululo ayiqulathanga kwisigcinakaliso, ngoko ukuba, kufuneka kutshatyalaliswa.

amanqaku edidayo: nokubuyekezwa ezintle nezimbi malunga ichiza. Bani ukuba ningakholwa?

Ichiza "Avastin", ncomo apho kukho kuzo ebezintle nezo zingentle ngokupheleleyo, nyaka ngamnye ngakumbi yaye ngokufuthi ngakumbi emiselwe ngugqirha. Lahamba ukuzabalaza ayasebenza kwezonyango unyango iintlobo ezininzi zomhlaza.

Kugweba ukusebenza unyango lwezigulane ungafumana ulwazi malunga nonyango iziyobisi "Avastin". Izimvo ezigulane sihlolisise on.

Eli chiza ixabiso eliphezulu ngokwaneleyo. Kwi-avareji, iqala amawaka 15. Thambisani. Ngenxa yoko, xa izigulane kunye kwezifo ejongene ngugqirha ukumphatha ichiza, ngoko nangoko baqalisa ukukhangela ulwazi malunga ichiza "Avastin" angqina nomonde, ukusebenzisa eli chiza, kunye nemiyalelo nokusetyenziswa kwayo.

Amaninzi ungafumana ulwazi malunga nonyango "Avastin" engagunyaziswanga iimeko ezinzima kakhulu. Asimele silibale ukuba akusoloko ugqirha imisela amayeza, baphonononge ngenyameko zonke bokuqonda oqondela ukuba ichiza "Avastin" umyalelo. Ukuphonononga malunga nefuthe elihle beziyobisi kwezi meko - a amila. Kuyimfuneko ukuba siziqaphele impilo yabo, nikhumbule ukuba unyango lwezifo ezifana nomhlaza, kufuneka kwenziwe kuphela ngabasebenzi abaqeqeshiweyo.

Kwimeko nganye, kukho izizathu ezininzi zokuba "Avastin" akanakuya isigulane kunye nokuququzelela indlela yesi sifo. Ngoko ke kufuneka ucinge cala kwaye ukhokelwe kuphela yi-ncomo ezimbi.

Cinga ezinye iimbono unyango kunye eli chiza.

Ukuphonononga malunga ichiza "Avastin"

Njengoko sele kutshiwo ngentla apha, ezi ncomo le mveliso amayeza ziyaphikisana kakhulu. Noko ke, izigulane ezininzi ingxelo ukuba unyango kwesi sifo ibonakala inkqubela enkulu. Kwezinye kukho ukuhla ubukhulu ithumba. Kodwa ke, ngelishwa, ukuchacha ngokupheleleyo akufunekanga kulindeleke. "Avastin" kuphela nako ukwandisa ubomi yomguli wenze kube bekhululekile ngakumbi.

Sasichaza a lot of amatyala yeziphumo ebezingalindelekanga. Eyona njalo wabona ukomelezwa yintloko, uxinzelelo lwegazi ngamandla. Iinaliti "Avastin 'emehlweni ezinye izigulane kukhokelela kwilahleko umbono kunye ziimfama.

Kwi-US, Bekukho ucamba enkulu phezu ukusetyenziswa "Avastin" kuba unyango lwe yamehlo macular. Inaliti beziyobisi waya vitreous kwakhokelela iseti epheleleyo yeziphumo ebezingalindelekanga. Ngelo xesha, 16 izigulane babengene usulelo kakhulu ukhozo lweliso. Abanye kuphuhliswa yimfama epheleleyo. Kodwa "Avastin" uqhubeke ukusebenzisa zombini yabaseMelika nabaseYurophu. Ezo ukusetyenziswa kwezi ichiza engekho ubungqina sinxulumana wokukhuthaza mthethweni, kwaye kunye iindleko phantsi ichiza kuthelekiswa ne "Lucentis" zomthetho, evunyiweyo ukunyanga yamehlo macular.

Umahluko kwixabiso kwala machiza sikhulu. Ngoxa i US ixabiso "Avastin" i $ 50, ixabiso "Lucentis" - 2000 eerandi. Qaphela ukuba, ukususela kwinqanaba Ngenxa inkangeleko iingxaki kunye neziphumo ebezingalindelekanga, kwakunye nokuphuhliswa endophthalmitis "Lucentis" akukho mgaqweni. Yiloo nto abantu abaninzi abasemngciphekweni kunye uthenga unofficial "Avastin".

Ngokutsho oogqirha abaninzi, yonke indawo inaliti indlela ithetha. Uphando efunekayo kule ndawo. Abanye babo sele zenziwe. Ngenxa yoko, wathelekisa izenzo bevacizumab kunye ranibizumab (izinto esebenzayo "Avastin" yaye "Lucentis", ngokulandelelanayo). Kukho izifundo ezimbini indawo, kodwa ke iziphumo zabo uphikise, kuba ngexesha lokuqala kujike kube ezikhuselekileyo, bevacizumab, kwaye eyesibini - ranibizumab.

Ukuza kuthi ga ngoku, iRashiya lakuphelisa iziyobisi ukuze zisetyenziswe zamehlo. Kodwa ungakwazi ukufumana umthengisi kunye ugqirha oza kwenza ngenaliti. Ophthalmologists bakhetha i "Avastin" kangako, njengoko basekhaya amayeza-commerce kuyaqhubeka kwanda. Ngapha koko, ukuba ukutsala ingqalelo yomguli kwi iinketho enganeno lula kakhulu.

Kulo mzekelo, kufanele kuqatshelwe ukuba izigulane ezininzi kunye AMD baba inkqubela ebonakalayo emva benza izithonga, "Avastin 'emehlweni. Ukuphonononga malunga nemiba zonyango ezincomekayo. In nje kwizitofu embalwa ichiza ewuthile ukudumba yamehlo, kwabakho ukuphucuka acuity olubonakalayo. Therapy kunempembelelo HIV kwangoko, kodwa emva kokuba iziphumo ebezingalindelekanga zenzeke. Kwakhona, ukuba nempembelelo ebonakalayo entle emva inaliti yokuqala ichiza awunanjongo ngokupheleleyo.

"Avastin" + chemotherapy: ncomo, unyango

Mu kuya kwa nshita ukubuyekeza ezingquzulanayo malunga nokusetyenziswa kweziyobisi zamehlo, uphando lubonakalise impumelelo "Avastin" ile ichemotherapy kwi unyango lomhlaza colorectal. Xa isicelo kwiirejimeni standard chemotherapy "Avastin" inceda ukunciphisa ubungakanani yamathumba colon. Ngapha koko, le unyango iziphumo yokuduka metastases sesibindi-78% yezigulane. Ngenxa yoko, kwisinye kwisithathu izigulane bakwazi ukwenza lo msebenzi, nto leyo phantsi imeko entle kunokuba ubomi ukugcina.

Kwakhona, isifundo kwafunyaniswa ukuba "Avastin" njengoko olusebenzayo izigulane abadala kwizigulana abancinane.

Esi sicelo, kunye capecitabine ichiza kwandisa iminyaka yobomi kwezigulane somhlaza colorectal iminyaka emithathu ukuya kwemihlanu.

Oku kunceda ukuba sandise ubomi nokunciphisa ukuyilwa metastases e umhlaza webele ngumhlaza non-amancinci iseli lung ludibaniso "Avastin" chemotherapy +. Izimvo ukuphathwa ezinjalo esihle. Nangona kunjalo, le meko ifana: okuba bachache ngokupheleleyo yinto encinci.

ukusebenza clinical

• Umhlaza Colorectal - ne co-unyango 'Avastin "kunye IFL (irinotecan, fluorouracil, leucovorin) inabela ukusinda nama-5 iinyanga. Isicelo "Avastin" kunye ichemotherapy kungandisa leminyaka ubomi kweenyanga 4.
• umhlaza webele kuwenza. Infusions "Avastin" 10 mg / kg emva kwesithuba seeveki ezimbini kunye paclitaxel ngokuphawulekayo ukwandisa amathuba lokunqunyanyiswa yophuhliso izifo. unyango olunjalo maxa wambi kuphucula ukusebenza ichemotherapy.
• umhlaza cell wemiphunga Non-amancinane. Unyango "Avastin" kunye ichemotherapy (apho iziyobisi platinum-based) kwandisa amathuba okuphila nokunyusa leminyaka yokuphila.
• cell carcinoma kwezintso. Sebenzisa 'Avastin "kunye interferon alpha-2a lwenze ixesha ukusinda xa kuthelekiswa usebenzisa kuphela interferon udibaniso lwe-2a.
• Isigaba sesine of glioma amabi. Emva kokuba pre-radiotherapy unyango "Avastin" kungalandisa ubomi phantse ezintandathu iinyanga.

Ngaloo ndlela, "Avastin" sisiyobisi mihla ukuba unyango yamathumba ezahlukeneyo. Isiphumo ichiza sele nezingaphandwanga ngokupheleleyo. Noko ke, oko liya kumiselwe ngoogqirha kwi unyango iintlobo ezininzi zomhlaza.

Izicelo "Avastin" zamehlo, apho inika isiphumo lolona eyakhayo unyango AMD. Ichiza lubiza kakhulu, naye kunokubangela iziphumo ebezingalindelekanga ezininzi. ingxelo Lilonke emva kokusebenzisa "Avastin" ezincomekayo, kodwa kukwakho negative.

Ngokuba ezinye izigulane, "Avastin" lwanto ngokupheleleyo, yaye ezinye nemiphumela engemihle. Ngoko ke, ichiza kufuneka onyule kuphela ugqirha ofanelekayo, kunye ingqalelo imbopheleleko yenu yonke impendulo kunokwenzeka ngamnye nomonde amacandelo zeziyobisi. Ngaphezu koko, nokuhlanganiswa kufuneka lwenziwe phantsi kweemeko abawaziyo. Cancer - isifo ezinzulu ezikhokelela ekufeni. Ukusetyenziswa ichiza "Avastin" ayithethi ukunika isiqinisekiso kwemeko yabo unyango, kodwa ukunqanda ukuqhubela phambili kwesifo kwaye kongeza imihla yesigulane. Ke izigulana izifo ezibulalayo abe deal enkulu!