"Insulin isophane": imiyalelo, analogs

Isifo seswekile - bagula kakhulu, nto leyo, ngelishwa, alunakupheliswa ngokupheleleyo. Njengoko usazi, kwisiqalo esi sifo kukho lunyhasho secretion kwamadlala zomzimba pancreatic. Kunye nezigulane badla ukumisela insulin eyenziweyo "Isophane". Le izinto ulawula inqanaba iswekile egazini, ukuqinisekisa ukusebenza eqhelekileyo yonke eziphilayo.

Kakade ke, izigulane anomdla naluphi ulwazi olongezelelweyo ngalo ichiza. Njengokuba kuchaphazela umzimba semi-zokwenziwa insulin "Isophane"? Imiyalelo, Izimo, izigulo kunokwenzeka ngexesha unyango - ingongoma ebalulekileyo, nto leyo eza kuxutyushwa kweli nqaku.

release Form

Yinto akukho mfihlakalo ukuba seswekile sisifo eqhelekileyo kwaye iyingozi leyo ifuna ukusetyenziswa kweziyobisi ezahlukeneyo, kuquka insulin. "Isophane" - igama yorhwebo ichiza, nto leyo umxube semi-ilungisiwe hormone. iziyobisi zifumaneke ngendlela kwesisombululo lolawulo ongama. Ichiza kuthengiswa ezineengqayi iglasi kwi-10 ithamo ml 40ME / ml. Ukulungiselela isisombululo usebenzisa amanzi okuhlamba ukuba ngenaliti.

Ukuba nezinye iziyobisi kunye nokwakheka efanayo kunye neempawu njengoko insulin "Isophane". Izithethantonye yona - 'Insuman', 'Protafan "yaye" Himulin ". Kufuneka ngokukhawuleza wathi abanjalo amachiza okwabiwa kagqirha kuphela, okanye ubanika endocrinologist.

Yintoni iimpawu ichiza?

Insulin "Isophane" le yincindi semi-zokwenziwa ene iimpawu ezifanayo iziyobisi eveliswe pancreas kwabantu. Ichiza kunciphisa isixa glucose egazini ngokomeleza iinkqubo lipogenesis kunye gluconeogenesis.

hormone Synthetic esinxibelelana receptors insulin of imifinya iseli, isebenze iinkqubo yokucolwa ngaphakathi kwi seli. Emva yokufakwa yokuqaphela waphawula ukusebenza enqanda ezithile, kuqukwa glycogen, pyruvate kinase kunye hexokinase.

Le nemiphumo ibonakala emva kweeyure 1-1.5 kuphela emva kulawulo isicombululo. Kuxhomekeka ithamo kunye umzimba ogulayo umsebenzi ezinintsi ye-insulin eyenziweyo baqaphela emva kweeyure 4-12 emva nolawulo. Le nguqu ithatha iiyure ezili-11 ukuya kuma-24.

Yayibubungqina ezingundoqo zokusetyenziswa

Ukulungiselela "insulin Isophane" lisetyenziswa kuhlobo lwesibini lwesifo seswekile (ifom insulin-oxhomekeke). Kwakhona isetyenziselwa insulin okwethutyana. Ngamanye amaxesha unyango olunjalo kufuneka seswekile Uhlobo lokuqala. Umzekelo, ukuqaliswa isisombululo sicebisa ukuba izigulane xa amagosa hypoglycemic musani ukumkhwelela yifuna.

Ukwaziswa kwemithetho ye-insulin wesintu emva iinkqubo ezithile yotyando. Eli yeza kusetyenziswa seswekile sokukhulelwa sinwenwa (olu hlobo sifo kwenzeka kwabasetyhini ngexesha lokukhulelwa). omama insulin bacebisa ukuba unyango ukudla akanaye yifuna.

insulin semi-zokwenziwa "Isophane": imiyalelo yokusebenzisa

Xa Uhlobo lwesibini zezigulane seswekile zifuna unyango lobomi. Umthamo yonke imihla, ishedyuli wolawulo - konke oku kumiselwa endocrinologist yakho. Kubalulekile ukulandela ngokungqongqo imimiselo abaziingcali. Kukho eminye imithetho jikelele ukusebenzisa iziyobisi "insulin Isophane".

• Isisombululo yenzelwe kuphela lolawulo ongama. Kwiimeko ezinqabe kakhulu, ugqirha wakho Sicebisa amayeza alawulwa intramuscularly. izitofu efakwa abavumelekanga.
• Ichiza akufuneki ziqhutywa kwindawo enye.
• Okokuqala kufuneka ukuba angcangcazelise igutyana izihlandlo ezimbalwa, uze ukudayala ngenani elithandekayo umxube nesirinji (umthamo ayilungiswanga ngamnye).
• Le Inaliti kufuneka wenziwe ngokukhawuleza emva ugcwalisa nesirinji.

Ezineengqayi ngesisombululo kugcinwe kwifriji kwi 2-8 degrees Celsius. Phambi kokuba kuqaliswe ichiza kuyimfuneko ukulinganisa amanqanaba iswekile yegazi. Akukho mzekelo akakwazi ukusebenzisa amayeza xa uphawula ukuba turbidity yesisombululo, ukuyilwa iidipozithi phezu kweendonga ebhotileni.

Ingaba kukho naziphi na Izimo?

Eli chiza ezinye Izimo - iinkcukacha iqulethe imiyalelo ukusetyenziswa. "Insulin Isophane" alisetyenziswa izigulane hypoglycemia. Izimo ubalisa insulinoma kunye hypersensitivity ukuya izithako iziyobisi. Kufuneka kuqatshelwe ukuba maxa wambi utshintshe inaliti kungaphumela uxabane kunye ukubonakala ezinye iziphumo ebezingalindelekanga.

ziphumo bezingalindelekanga kunokwenzeka

Le ukulungiselela kuyimfuneko izigulane insulin-oxhomekeke seswekile sinwenwa. Kodwa uthomalaliso ezinxulumene iingxaki eziliqela. Zeziphi ukunyhashwa kungakhokelela ukusetyenziswa kwamayeza "insulin Isophane '? Guide iqulethe ezi nkcukacha zilandelayo:

• Kuluhlu le ukuphazamiseka ixhaphakileyo ziquka negazi, ezo zihamba imbonakalo yabangxamayo, kunye urticaria, nokwehla okukhulu uxinzelelo lwegazi, ubushushu bomzimba ukwanda kunye ukubonakala nokudumba.
• isiphumo Eyingozi unyango insulin yi hypoglycemia - isimo ngomnye ukuhla amaqondo eswekile yegazi. Iimpawu iquka lipholi, nentliziyo ngokukhawuleza, ixhala, usokola ukulala, imvakalelo rhoqo yindlala. Loo kophulwa idla ngenxa oyidlayo ezingachanekanga, okanye ukungaphumeleli ukuthobela imiyalelo zikagqirha. Kwiimeko ezininzi kakhulu, nto iphuhlisa kwikhoma hypoglycemic.
• Ukuqaliswa konyango kwezinye izigulane ezinxulumene ongaboniyo. Lukhulu ukuba sikhathazeke yini wenze oko, ngenxa yokuba kwiimeko ezininzi, ezi ziphumo bezingalindelekanga bemke bebodwa.
• Kuluhlu ingxaki enokwenzeka ziquka reactions ngumzimba, leyo nazo va ukuqhelana imilo umzimba insulin.
• Ekuqaleni ichiza kunokwenzeka reactions ulusu, kuquka ububomvu kunye ukurhawuzelela. Badlule nazo ngokwazo.
• Ukuqaliswa amathamo ezinkulu kakhulu igcwele abagula ngengqondo. Kukho ucaphuka okwandileyo, ixhala, utshintsho zokuziphatha, ukuphuhliswa uxinezeleko.

Kuyabonakala ukuba ukusungulwa insulin "Isophane" kufuneka ngokocwangciso ebesiqulunqwe yi ngugqirha. Dlula inaliti sikhatshwe uphuhliso lactic seswekile.

Insulin "Isophane": nabalingani

Xa yesilungu, insulin zokwenziwa yabantu (sesichengeni elifutshane neliphakathi-term) asetyenziselwa ukulawula inqanaba iswekile le analogs hormone oluntu, kunye nemixube zayo. Kakade ke, imarike zoxubo inika emininzi iziyobisi ukunceda okwethutyana ukuphelisa iimpawu seswekile.

Kuluhlu analogue ziquka iziyobisi ezifana "Aktrafan", "Biogulin", "Diafan". Kwezinye iimeko, izigulane imithi ekucetyiswa "Protafan", "Humodar", "Pensulin". Not ezimbi insulins nayo njenge "base" yaye "Verein". Kuyabonakala ukuba ezi hormone - amachiza kakhulu kwaye usebenzise kuwo ngokuzimeleyo okanye kuyo nayiphi na imeko engenakwenzeka. ugqirha kuphela khetha analogu, yaye zijongisise idosi. Ngokomzekelo, phambi kwesi isisombululo wolongezelelo ubuncinane enye kwezinye izigulane kunokubangela impendulo omkhulu bagulayo ukuya umothuko anaphylactic.

Ulwazi malunga yokusebenzisana namanye amayeza

Phambi unyango kufuneka ngokuyimfuneko ukwazisa ugqirha wakho ekuthatheni amayeza. Synthetic isenzo insulin kunyuswa ulawulo ngaxeshanye kunye sulfonamides, adrogenami kunye steroid steroids, Mao inhibitors, iziyobisi nonsteroidal antiinflammatory. Isiphumo hypoglycemic yi ucaca ngakumbi kwisiqalo yokusetyenziswa ngaxeshanye "Isophane" ketoconazole iziyobisi, cyclophosphamide, umkhwinini, chloroquine, amayeza quinidine equlethe Lithium. Hi ndlela leyi, uthomalaliso ayikhuthazwa ukusela utywala, ethanol kuphucula ifuthe insulin zokwenziwa.

Estrogen, kontsratseptivy ngomlomo, glucagon, lweeHedfowuni, hormone buthathaka ifuthe ichiza. Kunjalo kwenicotine, intsangu, morphine, womchamo ethile (umzekelo, thiazide kunye loop), yokunciphisa tricyclic.

Xa kunjalo kubalulekile ukuqonda oko ngaphandle kwemvume likagqirha awukwazi ukutshintsha idosi okanye ishedyuli zolawulo insulin. Ukubonakala zeka abasabela ezibi kufuneka kuxelwe ezo endocrinologist kokuya.