Sequestrants acid bile, iziyobisi: uluhlu

ibizwa ngokuba uyadinga iziyobisi sequestrant acid, ziyakwazi ukunciphisa yegazi. Eli chiza abancedisayo ezisetyenziswa unyango. Kukho kudidi article zamachiza lipid-yandisa, nto leyo ethintela cholesterol kuhlelwe egazini. arhente Sequestering zibandakanyiwe kule yokuhlela. Ngoko lunemiqathango, iqulethe ezahlukeneyo izixhobo, nto leyo efana indlela yokusebenza. Kakhulu eyaziwa sequestrants acid inyongo - iziyobisi "Colestipol", "Cholestyramine", "colesevelam."

Umngcipheko nesifo sentliziyo kuncitshiswa sequestering iimpawu, kuquka ischemia. amava lwezonyango siqinisekisa ngokukuko SCF kule ngongoma zilandelayo:

• iingxaki ngesimilo coronary kuyehla;
• ababulawa lacuthwa iposi engabalulekanga.

Le khemikhali Ukubunjwa la machiza ivumela ukuba ziquka iindidi ze nentlaka ion exchange. Oku eliphezulu iikhompawundi ubunzima zokwenziwa molekyuli eyinxalenye Iipholima ezingenakunyibilika eqinile inxaxheba kunye eliphakathi zolwelo kwinkqubo exchange ion. Yiloo nto sequestering asidi inyongo.

Indlela yesenzo iziyobisi

Igama elithi "sequestrant" lithetha "yokwambathisa", oko kwenzeka emzimbeni bodwa abantu asidi inyongo. Cholesterol sibophelela nee-asidi inyongo; eziqulathe cholesterol osesibindini lokuhamba ukwenzela ukuba azise iincwadi ezo ehlaziya. Bile acid elijikeleza ometyiso phambi kokuba ukufikelela emathunjini apho kwelifunekayo. Ngenxa yoko, umzimba eninzi kwezinto ezibalulekileyo ebomini.

iziphumo abaphumelelayo lipoproteins ukuba abe mninzi eliphantsi. Oku njalo-amafutha embi.

Ekubeni sequestrants umsebenzi inyongo acid (amalungiselelo achaza ngakumbi ngezantsi).

Sequestrants Akukho bafakwe egazini, emibi kakhulu ukuba ikhona, loo mntu nqanaba lisezantsi, kwaye baza kuvela kunqabile kakhulu.

abasetyhini abakhulelweyo kunye phindeke zinokuthi zisetyenziswe kwezi zizathu. Kwakhona, abantwana abafikisayo kunye hypercholesterolemia kwiintsapho bathabatha la machiza ukuba isantya inkqubo. Le yimeko ilifa omzimba, apho cholesterol ngokukhawuleza ephakamileyo kunye neziphumo ngenxa.

Ukuba nokuthwaleka FFA eziqhelekileyo, ungasebenzisa kangangethuba ixesha elide. Noobyazatelno kufuneka ukulawula cholesterol, enzyme zesibindi kunye inyama kwezihlunu.

Statins ile FFA zinempumelelo ethe kratya xa ikhondo elide unyango. A cholesterol nokubi lifinyele ngesiqingatha. Ukuba kukho hyperlipidemia edityanisiweyo (xa kukho ezininzi kwamafutha egazini), ngoko ke iziphumo ziya kuba ngcono nge 70-75%. Njengoko isenzo umzimba kwi sequestrants enyongweni acid? Le imixube ukuba ukunyamezeleka jikelele kakuhle.

Ziziphi na iziphumo ebezingalindelekanga?

kukho iziphumo ezingalindelekanga kunqabile kakhulu. Ukuba, ke ngoko akuthethi ajike nto kakhulu ukuba umzimba. Sekunjalo, abanye abantu kuba ibonakalisa mpawu zilandelayo Kwathi kamsinya:

• nokuqunjelwa;
• ukuqunjelwa (ukuqunjelwa);
• isicaphucaphu;
• owabumba igesi kakhulu ethunjini (flatulence);
• ukuqumba;
• heartburn, yaye isiphumo kwicala lixhaphakileyo sequestrants inyongo acid.

Ukwenzela ukuphepha abasabela elibi ilungu lomzimba, kufuneka usele iziselo nidle ekuqaleni amayeza ngeedosi ezincinane.

Xa kusetyenziswa kids FFA kufuneka ukuba amisele intsimbi kunye folic acid. unyango ngaxeshanye kunye nezinye iziyobisi kunokubangela ukufakwa kakuhle kwamalungu asebenzayo. Apha kuyimfuneko ukuba agcine ulawulo ilandelayo: sequestering asele iyure emva ukusetyenziswa kwezinye iindlela, kwaye iiyure ezine ngaphambili.

buhlungu kakhulu kunqabile kunokwenzeka kwezihlunu (myalgia), ukudumba pharynx (umqala). Kakhulu ngamaxesha lubandakanywe nezenzo ukukhohlela, iintlungu komhlana, kubanda.

Izimo

Ngaba Izimo sequestering asidi enyongweni? Imithi engamiswanga kwezi meko zilandelayo.

Xa Uhlobo hyperlipidemia 3 no-4 (leyo ezisongela ezimbi yenkqubo sentliziyo) agcinwa sequestrants kucetyiswa. Zinokuzisa triglycerides egazini. Xa usindwa ngu inyongo bile (biliary kwesibindi kunye olupheleleyo isithintelo biliary) akakwazi nika imithi data. Ukuba umntu unesifo ukuqhina rhoqo, ichiza zingangunobangela kuphela meko. isifo sezintso, izilonda esiswini, hemorrhoids, ukopha disorder - zonke Izimo ku SLC.

Ngokukhathalela amisele nabo abantu neengxaki zesisu, malabsorption syndrome (kakuhle ukufakwa isisu, kunye nezondlo ezixabisekileyo kunzima ukuhlala emzimbeni).

isici nje kunokwenzeka.

Le look balandelayo sequestrants athandwa kakhulu inyongo acid. Iziyobisi (kuluhlu kwakhona ubuze ugqirha wakho) aya kulungiselelwa ukuze ukusuka kweyona idumile kancinci.

Ichiza "Cholestyramine"

Libizwa ngokuba "Cholestyramine". Ephindeneyo emahlamvini ion exchange ezingenakunyibilika. Oku kukhokelela ekuncipheni yi ikota kwamanqanaba yegazi. Ingaba i asidi esebenzayo inyongo esibophelelayo, zokuxhelela sisodwa ivela emzimbeni womntu. Ukuba ichiza kuyimfuneko ukuba basele ixesha elide, ngoko ke kufuneka usebenzise amanzi. Statins ukuphucula iziphumo, kodwa ingqalelo kuyehla egazini. Xa ndandineminyaka engama-60 emiselweyo ngononophelo.

Medicament "Colestipol"

It is a copolymer eliphezulu ezingenakunyibilika. Properties Jikela bile asidi mbi kancinane kuwo ngaphezu i "Kolestiramin".

Ziveza, iziphumo ebezingalindelekanga kunye Izimo ziyafana lonke iqela iziyobisi. Indibaniso "Kolestepola" kunye statins ukunika isiphumo ilungileyo.

Drug "colesevelam"

Akukho iimpawu ukunambitheka engasi imveliso inegalelo yokuba oko liya kusetyenziswa xa kuthelekiswa namanye amayeza.

Yenza i data sequestering asidi inyongo uneziphumo ebezingalindelekanga?

iziphumo ezingalunganga kwi iphecana zesisu kwaqwalaselwa. Ukusabela kunye namanye amayeza musa. "Colesevelam" zingasetyenziswa ukuba unyango kwabafazi abakhulelweyo kunye phindeke.