Triptans for migraine. Amaxabiso amachiza: Triptans

Migraine - ingxaki izigulane ezininzi. Phantse wonke umntu okungenani kanye buhlungu amava ukuphila entloko. Ngenxa umthetho, ukuba zihamba kunye nesiyezi, isicaphucaphu, ukugabha, kwakunye ndindisholo, ukuntlontlozela kunye ubuthathaka yesiqephu, faneleki kunye phonophobia. Emva uhlaselo, izigulane ezikhala ukudinwa, silale kunye ukozela. Ngamanye amaxesha kukho iimeko xa sifo ndenjenjalo ukubaleka, ezinokunceda kuphela triptans yintloko nomonde. Kufuneka kuqatshelwe ukuba migraine - isifo kwamabhinqa, njengoko mngcipheko mkhulu ngezifo ezifana, kunamadoda. Malunga nama-10-18% yabantu abadala une migraine.

Ingxaki yintloko eziqhelekileyo ukuze wonke umntu

Abantu abaninzi abazange bafune uncedo lonyango abaqeqeshiweyo uzama ukumelana nesi sifo, xa uthatha analgesics. Hayi ke, loo ndlela swi nga pfuna, kodwa kuwuvule kuphela sifo. Ukusetyenziswa kwamalweyile ngendlela analgesics kunokubangela uphuhliso kweziyobisi ngenxa intloko ezinganyangekiyo. Ngoko ke, ayimangalisi into yokuba kukho inani elikhulu imibuzo malunga olunjani iipilisi yintloko - kakhulu ngempumelelo.

Ngokupheleleyo kunyanga migraine akunakwenzeka, kodwa ukuphucula umgangatho wobomi kunokwenzeka iimveliso ezizodwa, apho ingonyulwa luvo. okwangoku Kukho aziwa isixa esikhulu of migraine ezisebenza ngokwaneleyo zombini ngexesha uhlaselo, kwaye kwithuba interictal. Emva koko, sihlolisise iziyobisi migraine: uluhlu lwezixhobo kunye nonyango ukuhlasela-free bukhali. Oku kubonakaliswa ukuba triptans - amachiza isebenzayo ukuphelisa yintloko ebuhlungu. Ngemithi umbala zinikezwa la maqela alandelayo:

• β-blocker;
• lakhula;
• antiemetic;
• amanzi-enyibilikayo vitamin B;
• blocker calcium;
• anticonvulsants.

Ukwamkela zonke ngentla zichongwe imithi kufuneka atyumbe umntu ofanelekayo.

Yini na ukuba nentloko ebuhlungu?

Phambi kokuba uqonde ukuba wenze njani triptans yintloko ebuhlungu, ixabiso elandelwayo exhomekeke umenzi, kuyimfuneko ukuba ukuqonda indlela leli ngezifo. Intloko ikhula ngenxa ukukhuthazwa receptors le meninges nempahla lobuchopho. Xa Ingxabano kakhulu kwaye lizele imithambo yegazi, ingakumbi imithambo, ibekwe zikwimeko hypotonic iphuhlise intlungu kakhulu, nto leyo lupheliswe kuphela ngokusebenzisa imithi ezizodwa. Abaphengululi abaninzi olwalufuna ixesha elide, amalungiselelo ngenxa yonyango migraine, ziye zagqiba ukuba triptans - iindlela ezingcono ukujongana le ngezifo.

izakhiwo triptans

Amachiza ejoliswe valiweyo iimpahla inimba ebuchotsheni. Triptans - iyeza ukuba enza izinto ngumongo kunye receptors ye-luvo trigeminal, nto leyo kunciphisa-ethe- mnyango intlungu. Triptans - iziyobisi antimigraine mihla, apho abe selectivity kunokuba eliphezulu imithambo yegazi lo mater Dura (Dura mater encephali) kunye neempahla okuncinane neuropathy kunye sentliziyo.

amayeza thaca iyasebenza ekunciphiseni intlungu kwinqanaba ngumongo spinal ye-luvo trigeminal. Ukongeza zonke triptans ngasentla - amachiza ezingenako ukunciphisa kuphela iziganeko ukuhluleka sifo, kodwa ukuphelisa wabonakala ezinxulumene lwezonyango ngayo (umzekelo, isicaphucaphu, ukugabha, photophobia, kunye nesandi).

Eyona engundoqo eziluncedo ze triptans

Ezi iimpawu amayeza ngesantya esiphezulu kudityaniswa isiphumo. Ngokoqobo kangangesiqingatha seyure kukho iimpawu nemiphumo emihle ichiza emzimbeni yesigulane. Isiphumo therapeutic lugcinwa kulo uhlaselo migraine. Uninzi lwezigulane yintloko akuthethi ziphinde zenzeke.

Kule mihla, izazinzulu ziye zabonisa ukuba ekufumanekeni izandulela ukuhlasela kufuneka ngoko nangoko ukuthatha triptans ukuze migraine. Ekuqaleni kwakukho ingcamango ohlaselwa migraine kufuneka ziphathwe ngezigaba, kuqalwa ulwamkelo amayeza ezilula.

Iziyobisi for migraine: uluhlu lwamayeza kakhulu ethandwa

Xa iqela triptan kwamachiza ibandakanya oku kulandelayo:

• 'Zomig'.
• "Amigrenin".
• "Sumatriptan".
• "Imigran".
• "Relpaks".
• "Trimigren".
• "Sumamigren".
• "Rapimed".
• "Almotriptan".
• "Naramig".
• "Naratriptan."
• "Frovatriptan."
• "Zolmitriptan."

Amachiza ukuba isigulane ngasinye babe ngqongqo ngamnye, ngoko ukuze kuqinisekiswe ukusebenza kwalo mthetho okanye ezinye amayeza, oogqirha yaleza ukuzama ukuthatha ngenxa yokuhlaselwa ezintathu migraine. iqela Tryptamine amachiza luphawulwa bioavailability phezulu, zibe lula ukoyisa umqobo igazi-ingqondo, iyasebenza ekunciphiseni ukuhlaselwa migraine, nkqu kwisigaba buhlungu. Ezi amayeza afanelekileyo ukumisela ukuba izigulane olungephi ukuya aqine kakhulu sifo.

Notes isicelo

Kaninzi sisiva umbuzo ofanayo: yintoni iipilisi yintloko ingcono? Izifundo Ukulinga aye abonisa ukuba le ndlela isebenzayo ukuphelisa iimpawu migraine ezi triptans. Kungcono ukuba triptans ukuze migraine xa sibona le miqondiso zokuqala ukuhlasela. Isiphumo esiphezulu iintlungu kuye kwaphawulwa iiyure ezimbini emva kokuba ukuthatha iyeza. Ngaphambi kokuba ichiza, funda ngenyameko imiyalelo aze adibane nogqirha. Kubaluleke kakhulu ukuthintela libanda, iziyobisi. Triptans kuba migraine ayikhuthazwa ukusebenzisa kunye nemithi, nokubola, arhente antiviral, kwakunye noxinezeleko.

Ukuphumeza oko akufunayo, izigulane kufuneka bathobele ezi zikhokelo zilandelayo Ukuphelelwa triptans:

• abangeva ukuba intloko ukumodareyitha ukuthatha 1 tablet (okanye omnye yesitshizi idosi);
• ithamo yesibini luthathiwe ngaphambi kwe-2 chasa;
• emini musa ukuthatha ngeedosi ngaphezu ezimbini;
• triptans akukhuthazwa ukuba uthathe iintsuku ezimbini ngeveki.

Ngexesha unyango odla ngayo mabangezi Products tiraminsoderzhaschie:

• kakhokho;
• chocolate;
• iimbotyi;
• amaqanda;
• celery;
• sohlobo;
• ngokutya okunesondlo;
• no;
• iitumato;
• nuts;
• iziselo ezinxilisayo.

Umntu kufuneka udle ukudla okubandayo.

Xa ukwenzeka migraine triptane, ixabiso apho ziya kuboniswa ngezantsi, nazo zingasetyenziswa kunye nezinye iziyobisi, ezifana metoclopramide okanye domperidone.

imiphumela emibi

Xa libanda, iziyobisi, izigulane bajongene le mingeni ilandelayo:

• nesiyezi;
• yashiya anaphylactic;
• yobunzima;
• isicaphucaphu;
• imvakalelo imfudumalo;
• iqhosha le udakada, amathumbu;
• ukuphalaza;
• umlomo owomileyo;
• myalgia;
• walunywa;
• ukozela;
• evuthayo imvakalelo esikhumbeni;
• Angioedema;
• tachycardia;
• ezindlwini;
• polyuria;
• buthathaka kwezihlunu;
• yehle ingqalelo;
• zemizwa;
• sorhudo haemorrhagic;
• Ukuchama rhoqo;
• vasospasm sentliziyo.

Phezu kwayo yonke le nto, triptans ukuba migraine - iyeza ekhawulezileyo-esebenza. oyidlayo isifundo rhoqo ukuthatha amachiza umngcipheko yeziphumo ebezingalindelekanga kuba ncinci. Ngokubanzi, zonke triptans zivunwe umzimba ngokwesiqhelo. ziziphumo ebezingalindelekanga, xa zithe zenzeka, ngoko wavakalisa wobulali ukusombulula ngokuzenzekelayo ngaphandle ungenelelo lonyango. Eyona ethile engundoqo triptans - oku iindleko zabo. Ngelishwa, asiyiyo yonke izigulane abanokufikelela ichiza enjalo.

Izimo

Triptans for migraine musa yaleza ukusebenzisa kwezi meko zilandelayo:

• ngesibetho;
• angina angiospastic;
• nokukhulelwa;
• ingozi cerebrovascular;
• ngexesha webele-ekondleni umntwana;
• coagulopathy (igazi ekunqandeni);
• esakhula;
• izifo nemithambo yegazi;
• hypersensitivity ezintweni bioactive le kuqulunqo;
• BP eyenzeke;
• arrhythmia;
• wesibindi nezintso izifo;
• yegazi.

Phambi emisela triptans ezithile, ugqirha ukuya kufuneka ukuchonga ubungozi ngenxa yegazi. Ezi zinto zibandakanya oku kulandelayo:

• diabetes;
• abafazi post-ngxaki;
• ukutshaya;
• wegazi;
• ukutyeba;
• olukumgangatho ophezulu yegazi engaqhelekanga;
• yobudala ngaphezu kweminyaka engama-40, ngenxa yabantu;
• yofuzo ukuba isifo sentliziyo.

Ezinye izigulane abasemngciphekweni kufuneka bafumane komthamo wazo wokuqala tryptamine phantsi kweliso ingcali naphantsi kolawulo ECG.

Scheme migraine ngokuphatha

Kukho imigaqo ngokubanzi yonyango unyango lwezifo ukuba sigwetyelwe kwiimeko ezininzi:

• kuyimfuneko ukuba ukuqala unyango kunye analgesics okanye izayamaniso yalo (kubandakanywa amachiza nonsteroidal anti-ukudumba);
• Ukuba ukusetyenziswa iintlungu asisiniki iziphumo ezidibanisayo, ngoko emva kwemizuzu engama-45 kufuneka athathe triptan;
• ukuba triptan sele lwayo, ukuhlasela olandelayo kufuneka asebenzise elinye ichiza kwiqela triptanovoy;
• yintloko ebuhlungu Nedlac kuyimfuneko ukusebenzisa non-steroidal amachiza-ukudumba.

Ukusetyenziswa izixhobo zale mihla ngenxa yonyango migraine, wadala ngokusekelwe triptans, ukunceda ukwenza ubomi lula ukuba izigulane ezininzi. Musa ukulibala ukuba ukuthatha ezi amachiza kufuneka amiselwe ngugqirha, kwaye kuphela xa uxilongo. Kukho iimeko apho triptans kunye nezinye analgesics nonspecific musa ukunika isiphumo efunekayo yaye akafuni ukuphelisa intlungu. Kulo mzekelo, oogqirha ngokuqhelekileyo amisele kwanonyango ezintsonkothileyo kunye amayeza anticonvulsant, beta-blocker. La mayeza ziquka amachiza zilandelayo:

• "Penbutolol".
• "Nadolol."
• "Betaxolol."
• "Topiramate".
• "Neurontin."
• "Phenobarbital".
• "Timolol".
• "Propranolol".
• "Labetanol".
• "Bellataminal".
• "Metoprolol".
• "Topamax".
• "Acebutolol".

Indlela yokunciphisa izehlo bahlaselwe?

Ukunciphisa nezihlandlo izigulane migraine kufuneka zilandele ngqo le migaqo ilandelayo:

• udle rhoqo;
• singasondeli ukudla kwakho ukutya neziselo engabangela ukuhlaselwa (utywala, itshokolethi, itshizi, champagne, iziqhamo citrus, newayini ebomvu);
• ukuyeka ukutshaya;
• njengoko kunokwenzeka ukuba abe ngaphandle elide;
• xiphephana;
• Ukuzilolonga (mqondo - ukuqubha);
• ukuphepha uhambo olude ngebhasi, isikhephe, imoto.

Triptans i yintloko: ixabiso

Triptans ziveliswa ngeendlela ezahlukeneyo idosi: izisombululo inaliti, ukutshiza ngeempumlo, amacwecwe, suppositories efakwa. Kwiindleko ichiza kuchaphazela ifomu ukukhululwa, umthamo, inani iipilisi kwi iphakheji. Ngenxa yoko, ixabiso la machiza yahluka kuluhlu olubanzi - engange 150-1500 pack nganye.