"TSifran ST": analogue, imiyalelo esetyenziswa kunye nexabiso

"TSifran ST" - ukuhlanganiswa kweziyobisi kunye zizinto esebenzayo tinidazole kunye ciprofloxacin. Kujongwe ukuba unyango kwezifo ezosulelayo le iphecana zesisu kunye nosulelo engumxube, naphuhliso olo olwaye negalelo aerobes kunye anaerobes.

Wazithwala phandle imveliso iintlobo ezininzi yamalungiselelo "TSifran". uhlobo ukukhululwa beziyobisi - amacwecwe wawutyabeka, amathontsi iliso, isisombululo ukumnika.

Tinidazole abunjwe ngayo imidazole. Imveliso iye antibacterial kunye nomsebenzi antiprotozoal, esetyenziswa izifo ezibangelwa anaerobes.

Ciprofloxacin ngowam olwa nawo, ephindezela uluhlu olubanzi lwemisebenzi. Kuye aerobic sifo (inkoliso aerobic, ezo gram-HIV, gram-negative).

Kanye yokuqala, yaye analogue "TSifran ST", ngempumelelo ukumelana nale misebenzi.

pharmacodynamics

Tinidazole leyo echaphazela anaerobes, iyasebenza ekunyangeni amalungu kwemiphunga achaphazelekayo ibekwe em- ngomlomo, kwi peritoneum kunye zangasese.

Ekubeni izifo anaerobic ngokubanzi zixubene (ziqulunqwe phantsi kwempembelelo aerobic kunye anaerobic), njengenxalenye ichiza ukho ciprofloxacin isibulala-zintsholongwane, nefuthe ngxelo imbi kwi iintsholongwane lilungu aerobes.

Pharmacokinetics

izinto ezingundoqo ezibandakanya iziyobisi yoqobo kunye analogue "TSifran ST", bathi bafakwe kakuhle iphecana zesisu zaza zahanjiswa zomzimba, neencindi zomzimba. Zabo eliphezulu xiyimiso waphawula emzimbeni emva umlinganiselo weeyure 1.5 emva kwii-ichiza kwisiqwenga zesisu.

Tinidazole has a bioavailability-100%, engagqibekanga ukuboniswa iiyure 10-12. Unxibelelwano iiproteni plasma ayinamsebenzi - 12%. Ekskretirovanie kuyenzeka inyongo, tinidazole malunga-25% kwazona kwi umchamo ingatshintshanga. Metabolites sele ziphelisiwe ngendlela efanayo. Inxalenye minor ye candelo lukhupha ivela emzimbeni endleni.

Ciprofloxacin ne bioavailability bamalunga nama-70% ye-ukusetyenziswa xa yangaphakathi kakhulu kakuhle ithathe. Zingene emzimbeni kunye nokutya, icandelo ethe isakhiwo salo "TSifran ST" (analogu imichiza esebenzayo) ako ngokucothayo. Ciprofloxacin enebana plasma kwi 20-40%. nethe Partial kwenzeka esibindini, isiqingatha idosi engena umchamo ibonakala ingatshintshanga. Malunga ne-15% ye ciprofloxacin kuthatha uhlobo metabolites neboniswe luhlobo 15-30% ye endleni zisuswe, inxalenye eseleyo - kunye inyongo. Kuba ukususwa ubuso kuthatha umlinganiselo iiyure 4 kodwa eli thuba kunokuba elide kubantu abalupheleyo, yaye ukuba isigulane ezivakaliswe iingxaki zezintso.

Iimpawu "TSifran ST" iziyobisi

Cinga amatyala ivumela apho ukusetyenziswa kwemali "TSifran" umyalelo manual. Price kunye analogue beziyobisi ukuqinisekisa impumelelo yonyango ezi zifo zilandelayo:

• izifo axubeneyo, naphuhliso olo olwaye kwenzeka phantsi kweempembelelo iintsholongwane (aerobic kunye anaerobic);
• sisisu segazi of etiologies ezahlukeneyo (amoebic elingumxube (bacteria kunye amoebic)).

Ichiza ofanelekileyo kunyango lwezifo ezahlukeneyo:

• iinkqubo esosulelayo ibakho amalungu zomlomo kwisisu (.. in t h periostitis, periodontitis);
• Izilonda elukhukweni;
• izilonda trophic, seswekile unyawo syndrome;
• iinkqubo ezosulelayo echaphazela izihlunu ethambileyo, isikhumba;
• e osteomyelitis ezingapheliyo;
• nezifo ezibangelwa intsebenziswano ezivele phantsi intshukumo ye gciwane (aerobes, anaerobes);
• izifo yamanina imvelo arhabaxa;
• zokugula peritoneum;
• empyema;
• ithumba lung;
• sinusitis, abacandayo kwifomu ezigulo ezondeleyo.

Izimo

"TSifran" ingasiwa kuzo zonke iimeko. analogs Ukubuyekezwa ukuvumela ukuba ukhethe iinketho olufanelekileyo unyango.

Imiyalelo othintela ukusetyenziswa kweziyobisi phambi ezinye iingxaki:

• izifo CNS eziphilayo;
• porphyria elibukhali oluvuzayo;
• Bone lomongo ngezifo (inkqubo hematopoiesis kakuhle);
• izifo egazini (kwimbali).

Izimo kwakhona hypersensitivity ukuya amacandelo amayeza, ukuzala, ibele-lwebele. Iyeza le nto yenziwa izigulane ongaphantsi kweminyaka eli-18. Imiyalelo "TSifran ST" awukuvumeli ukusetyenziswa kotywala.

Amayeza kwi abadala liye ezinye iimpawu ezikhethekileyo, ngoko qiniseka kuyimfuneko ukulandela izindululo gqirha khona. Isilumkiso iyafuneka xa:

• zolwaphulo ezivakaliswa wesibindi nezintso;
• States convulsive (imbali);
• sokuwa;
• isifo sengqondo;
• kwegazi engqondweni;
• yamafutha semithambo, ibekwe ebuchotsheni.

Ukusetyenziswa kweziyobisi, idosi

"TSifran ST", analog le echiza iindlela ezahlukeneyo isicelo kwaye zisetyenziswa ngeedosi ezahlukeneyo. Ukuqulunqwa original yenzelwe ukusetyenziswa lwangaphakathi, esithathwe emva nokutya (2 umphinda-ngosuku). "TSifran ST" wahlamba phantsi namanzi amaninzi. Akuvunyelwe ukuba baphule ingqibelelo cwecwe, kufuneka kuyisela ngokupheleleyo.

Ithamo Kucetyiswa ukuba abadala:

• tablets, ezibandakanya abo ciprofloxacin kunye tinidazole abakhoyo 250 no 300 mg, ngokulandelelana - iziqwenga-2;
• amacwecwe eziqulathe ciprofloxacin kunye Tinidazole 500 mg kunye 600 - 1-PC.

Ngokuba ukusetyenziswa mlonyeni ichiza kuba amehlo asha kufuna amathontsi enye okanye ezimbini iindlela. Unyango kufuneka wenziwe kudluliswe iiyure 1-4. Ukuba imeko iphucuke, ungenza ukwandisa lekhefu.

Effects ezingalindelekanga "TSifran ST" iziyobisi

"TSifran ST" (analogu kwezinto ezisisiseko) ukuze bandiqumbise ezinye ngayo ezingafunekiyo.

Sokugaya System:

• gepatonekroz;
• hepatitis;
• senyongo cholestatic (umngcipheko ephezulu yophuhliso yayo izigulane isibindi unesifo);
• utyatyazo, flatulence, iintlungu esiswini;
• isicaphucaphu nokugabha;
• incasa krakra kule metal emlonyeni;
• imnyama;
• kome mqukumbelo kwiinwebu lweHo- emlonyeni.

luvo:

• thrombosis echaphazela kwemithambo yobuchopho;
• niphele;
• ICP High;
• migraine;
• isiyezi, intloko ebuhlungu;
• ngayo ingqondo;
• ndiyabila;
• ukungalali;
• lafa;
• ubuthathaka, nokudinwa;
• yombono;
• peripheral neuropathy;
• dysarthria;
• iingxaki kunye nolungelelwaniso zeentshukumo.

Amanqaku kunye nezinye iziphumo ezingafunekiyo "TSifran ST" umyalelo. Ixabiso ezikhemisti analogue ukugqiba nje kuphela ukusebenza ichiza, kodwa ke ubukho ezinye iziphumo ebezingalindelekanga.

Iimvakalelo:

• ukungaboni;
• kutshintsha Isivamvo sokujoja;
• dysgeusia;
• buthuntu.

nemithambo yegazi:

• wegazi;
• utshintsho kwisingqi yentliziyo;
• tachycardia.

inkqubo womchamo :

• nephritis Embi;
• iingxaki kunye kukhuthaza umchamo;
• ukubunjwa izixa ngokugqithiseleyo umchamo;
• kidney sisilonda esidumbileyoesingaphakathi glomerular;
• umchamo kuwo ukwenza crystals ityuwa;
• nokuzimisela igazi nomchamo kuqamba.

Iimpawu kunokwenzeka of komzimba kunye nezinye iziphumo ezibi, utshintsho parameters elebhu, ukuphazamiseka ezahlukeneyo kwinkqubo hematopoietic.

imithi

"TSifran ST" (analogu yecandelo esebenzayo) akufuneki ukudityaniswa "ethionamide". Ichiza kudityaniswe kunye nemithi ethile kunye sulfonamides.

Xa kusetyenziswa ne "pentobarbital" waphawula yokunyusa ukutya. Ichiza kuphucula sisenzo ethanol kunye anticoagulants.

oyi

Ngexesha unyango kufuneka kancinci kangangoko ukuhlala phantsi kweempembelelo kwelanga. Akuvunyelwe ukuba benze imisebenzi ukuba unyango lwe ichiza engozini impilo (abaneemfuno zempilo, imbonakaliso ngokukhawuleza kweemoto kunye abasabela ngengqondo). Ngexesha unyango, esweni igazi yoluvo.

Analogs, ukubuyekeza, ixabiso

Xa kunikwa "TSifran ST" analogue, ixabiso zibalulekile kwizigulane. Iipilisi ezininzi ezisetyenziswayo ngokuqhelekileyo. Amacwecwe Iindleko ezinomthamo kwezinto ezisisiseko 250 no-300 nama-36-460 tablets engange ixabiso mg apho kukho 500 no 600 mg ezinkulu amacandelo - malunga 79-500 engange.

Yintoni indawo "TSifran ST"? analogs Russian abiza. Ichiza entsusa kutshintshwa, umzekelo, "ciprofloxacin" (10-25 engange). Indian nabalingani, ungakhetha "Tanidazol ciprofloxacin +" okanye "Tsiprolet A" (150-325 engange). Kuyinto la machiza ikakhulu indawo yi "TSifran ST".

Xa nokubuyekezwa, ichiza yokuqala alwa kakuhle ingqele eqhelekileyo, ingakumbi xa waqalisa isifo. Xa kusetyenziswa kwimihla yokuqala sexesheni, it ikuvumela ukuba kunyanga komtshiso abaninzi ababhinqileyo. "TSifran ST" ngokukhawuleza lula imeko yesigulane.

Ngokomthetho ukusetyenziswa zintsholongwane emva imisebenzi kwaye kwiimeko apho ukugeleza komtshiso kakhulu emzimbeni, nto leyo ixesha elide musa zinyamalale, ekubeni kukho iziphumo ebezingalindelekanga ezininzi kangaka. I-ncomo umthengi ukucacisa ukuba analogue azikho olusebenzayo zivunwe ngcono.

Drug "TSifran ST" kuthatha kuphela emva kokuba iimviwo kunye nogqirha zengqesho. Akukho mfuneko self-medicate, kuba imiphumo inokuba kakhulu.