Ukususela oko kunceda "Hypothiazid". "Hypothiazid": isikhokelo, ukubuyekeza, analogs

Namhlanje ke ndithi kuni, ukususela oko kunceda "Hypothiazid"? Kwakhona le mathiriyeli kweli nqaku liza kubonelela imiyalelo yokusetyenziswa kweli chiza, uhlolo yabathengi, imilo woyekelelo yayo, kunye nezinye iimpawu.

Inkcazelo yokulungiselela, imilo, nokwakhiwa zizinto ebekupakishwe

Ukususela oko kunceda "Hypothiazid"? Ngaphambi kokuba siphendule lo mbuzo, kufuneka ukuba achaze oko hlobo eli chiza uya ekhemesti.

"Hypothiazid" evela ngohlobo amacwecwe ezimhlophe (kunokuba nombala nombala). Zinelungelo setyhula kunye nemilo tyaba, umngcipheko kwelinye icala kunye nemiqadi "H" - kwenye.

Into elikhutheleyo hydrochlorothiazide kweziyobisi iziyobisi. Kwakhona iquka izinto abangabancedani ezifana magnesium stearate, monohydrate lactose, talc, awu kunye nombona istatshi.

Ekuthengisweni eli ziko ezinikiweyo Imiqulu blister, ezo zahlanganiswa kwiibhokisi kwikhadibhodi.

le mithi

Yintoni na ichiza "Hypothiazid"? Ukususela oko kunceda eli yeza?

Ngokutsho imiyalelo, ingqalelo ichiza a umchamo. indlela yayo engundoqo amanyathelo ukwanda diuresis ngenxa inhibition of reabsorption sodium kunye chloride ion kummandla yokuqala tubules sezintso. Le isiphumo kukhokelela ekwandeni kukhuthaza chlorine, isodiyam, kwaye, ngenxa yoko, amanzi.

Kufuneka kuqatshelwe ukuba, emva kokufumana medicament uthe kwandisa kukhuthaza kwezinye electrolytes, ingakumbi potassium nezinki.

Ngeedosi eziphezulu zonyango iziphumo natriuretic kunye umchamo kweli chiza ziyafana.

Diuresis kunye natriuresis kwenzeka ukuba imizuzu 120 waza wafikelela izinga eliphezulu emva kweyure 4.

Kufuneka kuqatshelwe ukuba medicament kunciphisa umsebenzi anhydrase గుర్తులు ibhaloni ngokwandisa yesoda ion zinomgutyulo. Noko ke, le isiphumo ichiza amandla kwaye aluchaphazeli pH yokuchama.

mbewu "gipotiazid" Active anazo iipropati umfutho. Asinako ukuba iyeza phantsi ingqalelo alunasiphumo kwi uxinzelelo lwegazi yesiqhelo.

Le kinetics beziyobisi

Nokuba iyeza ako "Hypothiazid"? Imiyalelo, ingxelo lencazelo ukuba hydrochlorothiazide ayikho ngokupheleleyo, kodwa ako ngokukhawuleza kakhulu ukusuka kwinkqubo yokwetyisa. Le isiphumo kulwa iiyure 6-12.

Xa ekufumaneni ichiza ngomlomo kukho umthamo 100 mg ukuzikisa ingqondo yayo incopho kuphunyelelwa emva kweeyure ezi-2.5 plasma.

Unxibelelwano kunye iiproteni plasma yi-40%.

Ngokutsho kweengcali, hydrochlorothiazide iyekelela kunye nobisi lwebele kwaye ingene nge njengomqobo placental.

Kukhuthaza isixhobo eyalo izintso kwisithuba seeyure ezi-6.

Medicament "Hypothiazid": yintoni esiza?

Eli yeza omiselwe:

• uthintelo owabumba lityeni womchamo kubantu kubuphepha esi sifo (ukunciphisa hypercalciuria);
• lwegazi (monotherapy okanye zidityaniswe namanye amachiza umfutho) ;
• ukulawula polyuria (ubukhulu becala nephrogenic diabetes insipidus);
• Nokudumba syndrome imvelaphi ezahlukeneyo (ingcinezelo premenstrual syndrome, nephrotic syndrome, ukusilela kwezintso, indalo esinganyangekiyo, glomerulonephritis etsolo, unyango corticosteroid, ukusilela intliziyo congestive indalo esinganyangekiyo, lwegazi portal).

Izimo

Isibakala into eyenza "Hypothiazid" samxelela ngasentla. Kwakhona bazazi Izimo esi sixhobo. Ezi ziquka:

• Abantwana abangaphantsi kweminyaka emithathu ubudala;
• ukusilela kwezintso obunzima;
• anuria;
• isibindi obunzima;
• isifo Addison kaThixo;
• diabetes esingaphathekiyo;
• hypokalemia elinjubaqa, hyponatremia, hypercalcemia;
• anda ubuntununtunu iziyobisi, kunye nezinto yemvelaphi le sulfonamides.

Ngononophelo kakhulu kufuneka kusetyenziswe esi sixhobo izifo kobuchopho entliziyweni, hypokalemia, isibindi ukuqina, hyponatremia, sifo, hypercalcemia, isicelo of glycosides kwentliziyo, ukunganyamezelani lactose, kunye nabantu abadala.

Drug "Hypothiazid": imiyalelo yokusebenzisa

analogue Izimvo ingqalelo amachiza thaca ekupheleni kweli nqaku.

Iipilisi kufuneka athathwe emva kwesidlo. umthamo wabo ezikhethiweyo ngethuba unyango, qho ngamnye.

nomthamo lokuqala ichiza yabantu abadala:

• premenstrual imimoya syndrome: iyeza iqala kuqala iimpawu phambi kokuba sexesheni (in-mali ka-25 mg kanye ngosuku).
• syndrome Edematous imvelaphi ezahlukeneyo: 25-100 mg kanye ngemini okanye kanye ngeentsuku ezimbini. Kwiimeko kakhulu, iyeza emiselweyo mg 200.
• Lwegazi: 25-50 mg kanye yonke imihla. Isiphumo therapeutic beziyobisi wabonakalaliswa iintsuku-4.
• Nephrogenic diabetes insipidus: 50-150 mg imihla (ngeedosi ahlukene).

Njengoko ngenxa yoonyana; kuba ingqalelo ichiza emiselweyo esekelwe kwi ubunzima. Idosi yemihla ngemihla ka-1-2 mg / kg.

imiphumela emibi

Ngoku wena uyazi yintoni eyenza "Hypothiazid". Nangona ukuthatha le iyeza lisenokuba reactions ecaleni zilandelayo:

• ukudla, umlomo owomileyo, amahlaba kwezihlunu, sorhudo;
• nobuhlungu bomzimba, ukuqhina, ukudinwa, cholecystitis, ubuthathaka, senyongo cholestatic;
• silale, pancreatitis, unxano, sialadenitis;
• arrhythmia, igazi aplastic, vasculitis, thrombocytopenia, intloko ebuhlungu, leukopenia;
• isiyezi, igazi hemolytic, umsebenzi kidney ukuphazamiseka, agranulocytosis, kunye nabanye.

Analogs kunye ukubuyekeza ichiza "Hypothiazid"

Izimvo "hydrochlorothiazide" ingxelo ukuba i umchamo esebenzayo ngok-ngokwenza. Ukwamkela macwecwe kuthintela ukuyilwa amatye womchamo, zehlisa uxinzelelo lwegazi kwaye ishenxisa ekweneni imvelaphi ezahlukeneyo.

Bobubi amachiza ingqalelo baphathe inani elikhulu ngayo ezibi.

ngendlela efanayo yale echiza: "hydrochlorothiazide", "Hydrochlorothiazide-chap", "Dihlotiazid", "hydrochlorothiazide-Verte" kunye nabanye.