Yeyiphi engcono - "Prednisolone" okanye "metipred"? Yintoni umahluko?

Ukhetho Ilungelo imveliso - isiseko unyango olukhawulezileyo humelelaka. Kwimarike imithi, kukho iziyobisi ezininzi ezizodwa kunye nalawo, ngokunjalo nayo indoda kude isuswe kwihlabathi amayeza, ukwenza ukhetho zicwadi kunzima kakhulu kwi ekhemesti.

Kulo mzekelo, lo mbandela mkhulu xa uthenga iyeza izenzo ngexabiso layo. Noko ke, umgaqo efanayo ntshukumo ichiza kunye nokwakheka ayisoloko akuqinisekisi isenjalo nothomalaliso. Xa kuziwa iziyobisi kunokubangela iziphumo ebezingalindelekanga ezimandundu, ukhetho amayeza kufuneka silumke kakhulu. Kuyimfuneko ukuba ukuphulaphula icebiso oogqirha, ngokwabo ukuqonda umba umahluko ezifanayo phakathi nemixube ezimbini iziyobisi.

ubungqina

Ngaphambi kokuba siqonde imbambano malunga loo nto ilungileyo: "Prednisolone" okanye "metipred", umele uqonde ukuba kutheni kufuneka la machiza. Ukubunjwa zombini mali ijolise ukucinezela omzimba, oko kukuthi, ukunciphisa amajoni omzimba. Nangona kubonakale ngamazwi, ngokuba umba yokwandisa amandla okukwazi olukhulayo ngokuthandwa nokufaneleka, immunosuppressants ezibalulekileyo ukuze ukunyanga ezahlukahlukeneyo izifo.

isifo samathambo - iinkqubo apho amajoni omzimba womntu iqala ukuhlasela iiseli zalo. Oku kubangelwa yinto yokuba usuleleko lingena singene yeseli, latyhaphaka ngaphandle kokutshabalalisa iseli, akunakwenzeka. Xa iseli osulelwe, umzimba uqalisa ukuvelisa omzimba athile leyo kujikeleziswa emzimbeni uze utshabalalise iiseli alo.

Kulo mzekelo, kuyaphawuleka ukuba antibodies angaba "ephosakeleyo," aze ahlasele amalungu abo cell iqumrhu elikumila kunjalo, ezifana intliziyo kunye nezintso zidla ithagethi ye immunoglobulin isazama throat emqaleni.

Izifo komzimba namhlanje asikuko nokuba kuyabulala, ngoko nkqu nasemva kokuba usulelo sisusiwe, izilwa ziyaqhubeka kuphuhliswa. Kwimeko ilungileyo, esi sifo ingena kuxolelwe, kodwa phantsi kwempembelelo nasiphi na isizathu (nomothuko, ingqele, ukutshintsha kwemozulu, ukukhulelwa), ukuba unako ukubuya. Ukuba isifo ayikho imo yokucima ngenkuthalo atshabalalise amalungu zeethishu, kuyimfuneko ukuba ibe kuxolelwe eyenziweyo ukuya "kwakhona" amajoni omzimba.

"Prednisolone" okanye "metipred" umsebenzi amajoni omzimba kuncitshiswa ukuba ubuncinane, ekufezekiseni ukuba lomzimba ayisekho zaveliswa. Emva kwekhosi, okuhlala-avareji ukusukela ku iinyanga ezimbini ukuya ezintandathu, umthamo ichiza aqale ukunciphisa kancinane, ndivuka impendulo yakho omzimba. Ukuba unyango kuphumelela, amajoni omzimba iza kusebenza kakuhle de exacerbation elandelayo. Nangona kunjalo, kukho iimeko xa kuxolelwe emva unyango kunye corticosteroids ithatha yobomi.

imiphumela emibi

Ukuqwalasela lo mbuzo oko kubhetele - "Prednisolone" okanye "metipred" kunqabile zibandakanya ukusebenza ngqo, njengoko ubungqongqo isiphumo ixhomekeke ngamnye kwaye hayi kwi umahluko phakathi ngezakhiwo ezimbini.

Iziguli unyango immunosuppressive, kuphephe side effects anayo izixa ezikhulu kwaye, yaye kwelinye ichiza.

umzimba

Isiphumo engundoqo elijongene uninzi lwabantu abafumana unyango glucocorticoid ixesha elide - inzuzo weight. Lokugaya impela abawayo, yaye umphefumlo, kwelinye icala, wandisa khona unyango lwamachiza hormone. Kodwa oyena nobangela inzuzo lokulinganisa ukugcinwa fluid emzimbeni. Ukuba esweni ngenyameko output umchamo kesodiyam bagqitywe, Nongeniselo ubunzima inokuphetshwa, iziyobisi ndiqononondise ubuso pasty kuphela, wamqumbisa ngokuphuhlisa uthomalaliso lwe Cushing engqondweni. ingxaki iqhubeka ngokwayo kunye iidosi ukuhla.

diabetes

Ingxaki eziqhelekileyo wesibini ejongene izigulane abo bathabatha iziyobisi immunosuppressive - seswekile steroid. Kwizigulane besebancinane, imfuza, nto leyo saxineka zizifo yonyango, seswekile akuyona ingozi enkulu, emva kokuba ukucinywa amanqanaba ulwamkelo glucose kunye insulin leyo izinze.

isilonda esiswini

Ke ekugqibeleni, iziphumo ebezingalindelekanga sesithathu ixhaphakileyo - isilonda esiswini. amayeza Modern engenalo phantse ngokupheleleyo ukungxamiseka kwale ngxaki ngokusebenzisa ukutya ezizodwa kunye neziyobisi ekhusela isifo esiswini ebudeni unyango. Kwimeko yokuba isigulane aphathe ngenyameko zonke iingcebiso kagqirha, bafumana ezimbi emathunjini uya kuziphepha.

Kukho kwakhona emibi ezifana sexesheni ezingafanelekanga, uphuhliso lwegazi kwamathambo. Izigulane ezininzi kufuneka kwandiswe nochuku, ugwayi.

Ngaba kunokwenzeka ukuba siphephe imiphumela emibi?

Uluhlu yeziphumo ebezingalindelekanga xa uthatha glucocorticoids kakhulu umxhelo kunye nenani iziphumo ezilindelekileyo kunye lazo. Ngelishwa, akukho ndlela nya ngokupheleleyo, kodwa kuncitshiswe kubo real kakhulu. Kungenxa kule Uxhulumaniso nanku umbuzo, loo nto ilungileyo: "Prednisolone" okanye "metipred"?

Zombini mithi nobuni efanayo kunye nendlela efanayo yesenzo. Noko ke, "metipred", ngolwimi oosokhemisti, ngakumbi iziyobisi "ezicocekileyo". amacandelo ngamanye amazwe apho ichiza baba ezinokuntsonkotha multi-isigaba intlambululo yokusihlambulula ngaphezu koko ye-analogue, ngoko kunciphisa iimpembelelo enetyhefu ngexesha ulwamkelo kunye neziphumo ebezingalindelekanga kuyehla.

Xa kufikwa ukusetyenziswa elifutshane elide corticosteroids, ezifana negazi, camngca komxholo othi: "Prednisolone" okanye "metipred" - into ukukhetha, awungeni. Esebenzayo izakuba nasiphi na isiyobisi, kodwa enyanisweni ke ixesha elifutshane ukusetyenziswa kwayo ayiyi kunika naliphi na ithuba kuvela icala elingenzi nto-ezidweliswe ngasentla okanye ube nefuthe yityhefu kwi emzimbeni. Kodwa ukuba uthomalaliso ibalwe kweenyanga, iziyobisi "uhlambulukile" iya kuba ikhuseleke kakhulu.

Kukholelwa ukuba xa ubungqongqo iziphumo ebezingalindelekanga singayenza ukuba kuzityumza glyukortikosteroidy ekuseni.

Nokwabela "Prednisolone" okanye "metipred" ngethuba lokukhulelwa, oogqirha ukhetha ukuba evuthisayo kulo mzekelo, uthathwa nje umbuzo ukusebenza unyango ngenxa nomonde, kodwa nokhuseleko olungekazalwa.

ukusebenza mineralocorticoid

Ukuhlalutya umbuzo apho kubhetele - "Prednisolone" okanye "metipred", kubalulekile ukuqwalasela into enjalo nempembelelo mineralocorticoid. Le nkcazelo iboniswe ngumkhuba enxulumene nokugcinwa sodium. Oku kukhokelela nokudumba, uxinzelelo oluphezulu lwegazi, nto leyo eqhelekileyo ukuba ulwamkelo emzimbeni, ubuso ngeenxa zonke.

Ukwakhiwa "metipred" ivumela isodium akuthethi lusala umzimba, ngenxa apho ingxaki 'umntu Kushingoid "kwi iziguli unyango nalo eli chiza, iqapheleka ngaphantsi abantu abathatha" Prednisolone ".

kunomphumela ophawulekayo

Izifundo ngokuhlola isiphumo kwezonyango phakathi amachiza amabini, wabonisa akukho mahluko umgaqo. Isiphumo unyango esekelwe iimpawu womntu, le comorbidities isifo esithile.

Ifumaneka kwimithombo eyahlukeneyo ngamalungiselelo ezifana "Prednisolone" okanye "metipred 'ncomo badla ukuthetha malunga ukusebenza kwale yokuqala. Nixolelwe "Prednisolone" kwenzeka ngakumbi ngokukhawuleza, nge-avareji, yathatha ixesha elide.

iziyobisi replacement

Ukuze ufumanise indlela kwimeko ethile, "Prednisolone" okanye "metipred" - kokona kulungileyo, unga zama zombini kwaye uthelekise isiphumo ichiza. Ukuqala unyango "prednisone", ungaya 'metipred "ngaphandle kokutshintsha idosi. Ngenxa yoko, 1mg "prednisolone" 1 mg "metipred" twatse ngokupheleleyo.

Nakuba kunjalo, ukutshintshwa ichiza kufuneka abe phantsi kweliso gqirha.

Immunosuppressants, nezifo

Ngokukhetha lichiza ethile ukuba unyango, izigulane ezininzi unomdla ukusebenza amachiza isifo esithile. Oko kukuthi, umbuzo othi "Prednisolone" okanye "metipred" - nto leyo ilungileyo samathambo, glomerulonephritis okanye enye ngezifo, siyasebenza kakhulu.

Ngenxa kuqamba efana kunye zibonisa ukuba ukuyisebenzisa, oko Kungaphikiswa ukuba umahluko esisiseko ekuqeshweni immunosuppressants ayikho. ugqirha xa ukhetha ichiza, uxhomekeke ngamava akhe kunye nocazululo apho iziyobisi isigulane kunye sifo, ubudala, isini, wathwala bhetele, oko kungakhokelela kubunzima waza wabonisa ukusebenza kakuhle.

Neendleko zamayeza

Ukuqwalasela umbuzo "Prednisolone" okanye "metipred" - kokona kulungileyo, akunakwenzeka ukuba ngoyaba umbuzo kweendleko iziyobisi. "Metipred" sisiyobisi olubiza kakhulu. ixabiso layo kwi-avareji eRashiya engange-200, ngoxa ixabiso "Prednisolone" isusela ukusuka engange-50 ukuya kuma-70. Iindleko kweemveliso Russian mixhesho ngokwemveli, kodwa ukubuyekeza phezu immunosuppressants basekhaya kwi-avareji unobubi ngaphezu import.

Ngenxa yokuba ukusetyenziswa corticosteroids isifo samathambo ithatha iinyanga ezintandathu ukuya yokwamkela ubomi, kucacile ukuba izigulane ezininzi ukubaluleka yomenzeli abakhethelwe unyango leyo kakhulu lula gingci lwabiwo mali lwanyanga-zonke lwakho. Enye into ebalulekileyo ezimiselweyo kunye ekufumaneni amachiza "prednisolone" okanye idosi "metipred", ekubeni izinga into esebenzayo kwaye isantya ezinkulu.

Ngoko ke, impendulo yombuzo "Prednisolone" okanye "metipred": kuba kokona kulungileyo, kuba umntu. Xa ukhetha ichiza kubalulekile ukuba uthathe ingqalelo yonke umfanekiso bezonyango isigulane, bonana nogqirha wakho uze ukhethe ngokwabo iziyobisi kunye umlinganiselo babo ukuze isiphumo sele livakalisiwe, yaye iziphumo ebezingalindelekanga musa kakhulu izinga yomguli ubomi kwaye musa ukuthwala isoyikiso empilweni yakhe.