Yintoni Lynch syndrome? Lynch syndrome: oonobangela, iimpawu, unyango, uthintelo

Yintoni na syndrome ka Lynch? Le ngezifo ilifa, ebonisa ukuthambekela umhlaza colon oluntu kunye nezinye zomhlaza ezithile.

Kukho nezinye izifo kwandisa umngcipheko ukuphazamiseka oncological, nangona kunjalo, lacazulula urhulumente yeyona iyingozi kakhulu kwaye kunayo yonke. Ngokutsho manani erhabaxa, zonke izigulane ezintathu ngaphandle kokuba iimeko ezilikhulu lomhlaza colon ubunzima Lynch syndrome. Esi sifo luyasuka kwizizukulwana ngezizukulwana.

iimpawu

Le ngezifo akuthethi ukuzibonakalisa - kusoloko iimpawu ndingekho. Bakrokrela ukuhlukunyezwa kunokuba ngenxa yezi zizathu zilandelayo:

• umhlaza ikholoni leyo yaphuhliswa besebancinane kakhulu (ngaphambi kokuba afike kwiminyaka engamashumi amahlanu);
• data kwi izehlo lomhlaza colon eselula kakhulu, ukusinda imbali yosapho;
• ulwazi kumatyala lomhlaza zesibeleko (umhlaza endometrial) imbali yosapho;
• ulwazi usapho imbali ebonisa nezihlandlo sifo kwezinye imihlaza, correlating kunye ezimbi ngentla (umhlaza zamaqanda, izintso, isisu, amathumbu amancinane, isibindi, amadlala umbilo njl njl).

Ukuba uyoyika ukufumanisa kwi Lynch syndrome, ebangela, iimpawu, kwaye amanyathelo afanelekileyo diagnostic kufuneka kuxoxwe yincutshe. Udibane nogqirha xa nayiphi na intandabuzo phezu ngezifo, kwakunye ngokungathi isihlobo sakho sisondele kwafunyaniswa le meko.

izizathu

Lynch syndrome ezidluliselwa ngendlela lubalaseleyo autosomal. Oku kuthetha ukuba, ekho sofuzo mutated kumzali omnye amathuba kuguquka-50% iya kudluliselwa umntwana ngamnye. ukudluliselwa isifo lomngcipheko komntu akuxhomekekanga ekuzithandeleni besini yomzali okanye umntwana.

Ufuzo zofuzo kubangela umhlaza

Zofuzo athwale Lynch syndrome, zikarhulumente zesiqhelo unoxanduva lokulungisa iimpazamo ikhowudi yemfuza. Kungenjalo, zibizwa yemfuza, onoxanduva kukulungiswa iziseko unpaired.

I-gene iqulethe DNA, leyo adlulisele imiyalelo ukuze imichiza nganye emzimbeni. Njengoko iiseli zikhula kunye nabelane, ukuba ekunabiseleni DNA zabo yaye maxa wambi umkhwetha iimpazamo ezincinane.

iiseli Eqhelekileyo ilifa iindlela ezikhethekileyo yokuchonga ukulungisa iimpazamo. Nakuba kunjalo, abantu abaye ilifa imiqondiso lwezidumbu, abanalo ukukwazi ukulungisa ezi nguqu iseli minor. Ukuqokelelela iimpazamo esinjalo sikhokelela ukwandisa lomonakalo phakathi kwiiseli, yaye ekugqibeleni ezi seli zibe ngumhlaza.

unyango

Umhlaza colon kunye nezinye izigqeba ezinxulumene Lynch syndrome baphathwa ngendlela enye njenge umhlaza oluqhelekileyo. unyango amaninzi kubandakanya ukwenza utyando ukususa organ abachaphazelekayo. Ngokuqhelekileyo, oko ikholoni okanye amaqanda kunye esibelekweni. Ukuba ungumfazi kwaye kwafunyaniswa Lynch syndrome, oogqirha banokwenza ukususa amalungu obuni zangaphakathi ngoko nangoko emva kokuba azale oluthandwa inani labantwana. amanyathelo azizithintelo ngohlobo kotyando - bungqinelwa ndlela iphumelelayo yokuthintela ukufa ngumhlaza.

ukuvimbela

Thatha impilo yakho phantsi kolawulo, athathe amanyathelo afanelekileyo:

• Landela siseko yokudla elungile, nidle iziqhamo kunye nemifuno. Khetha iziqhamo ezahlukileyo ukuya menu nakaloku, kwakuyakuhlala ngokupheleleyo. Nanini na kunokwenzeka, khetha ukolo.
• Sibonise rhoqo. Zama ukuba banikwe imizuzu engamashumi amathathu imisebenzi zemidlalo - ukuba yonke imihla, ubuncinane iintsuku ezintlanu ngeveki. Ukuba ukubonakalisileyo umsebenzi okhethekileyo emzimbeni, zikuxoxe oku nogqirha wakho. Qala kwiiklasi elula, ezifana umgama ukuhamba okanye ukuqhuba ibhayisikile.
• Bukela ubunzima bakho. A ukutya okunempilo umthambo rhoqo kuya kukunceda ukugcina ubunzima yesiqhelo. Ukuba abatyebe kakhulu, thetha wayeyingcali, bakwazi ukumisela inkqubo ngokupheleleyo umzimba. Eyona ndlela ilungileyo - ukudla ukutya ngaphantsi ophezulu-osidingayo, kwaye ngexesha elinye ukwandisa inani umsebenzi ngokwasemzimbeni. Lwela ukuba unciphise umzimba kwindawo wesikiti okanye ikilogram ngeveki.
• Ndiyeke ukutshaya. Ukutshaya kwandisa ingozi yokuba iintlobo zomhlaza kunye nezinye izifo ezinzulu. Ngokutsho kwezinye izifundo, ugwayi kungaba ukuqala umhlaza colon kwizigulane kunye Lynch syndrome.

Unamathela imigaqo elula ukuba yokuphila esempilweni kwaye kakhulu kuza kucutha umngcipheko ukwenza izinto sifo.