Acetyl acid

Eli yeza mhlawumbi edume kakhulu ehlabathini yaye iyeza lwekhabhinethi kwindlu nganye. Acetyl acid, nezaziwa ngokuba aspirin, wabonakala eYurophu ngenkulungwane XVIII. Kodwa hayi ngendlela apho sibona namhlanje.

Yaba ixolo yomthi, sihlangulwe ePeru, apho amaNdiya baphathwe fever ekhaya. Igama Indian "Kin-nakwinye inyama yenyama" yaba, kuyabonakala ukuba, kunzima ukubiza ukuba abemi baseYurophu, yaye "nakwizizalwana-ngowenyama yenyama" labizwa ngokuba "umkhwinini". Ixolo bayisile ibe ngumgubo kwaye osetyenziselwa umkhuhlane. Iindleko amayeza ngeyona ndlela iphezulu, ngoko waqalisa ukukhangela umntu ukuba enjenjalo.

In 1850th salicylic acid iye ingadibani willow (ngokuzenzekelayo, willow Latin - "salix"). Kodwa ichiza axhoma kakhulu. Kwakhona waqalisa ukuya kufuna indawo. Kuye kwafumaniseka ukuba asidi uqulathwe kwenye etyholweni - uzibulele. Yaye isixa-mali enkulu kakhulu willow. Kodwa Ozahlulayo yangaphakathi axakane kakhulu kwaye yokufakwa abangekho evumelana. Imbali ithe cwaka, kunye ingcamango abeza ukudibanisa ukuya acetyl wafumana iziyobisi (ethyl) olukhulu. Igama "aspirin" wasincamela unobumba wokuqala elithi "acetyl" kwaye ingcambu ye zomthi igama "-spir-". Imveliso Industrial of phenol, aspirin kwaqala ngo-1893.

Akukho iyeza ayinakuze ithelekiswe ne-aspirin xa umba umthamo: kwi-US yavelisa malunga 12 lamawaka iitoni ngonyaka!. Ezikhemisti zethu eyaziwa ngokuba aspirin, acetylsalicylic acid, kodwa kuqulunqo yenziwa yi mveliso ezahlukeneyo nangoku phantsi amagama 60.

Acid Ekuqaleni acetyl isicelo kuphela ukunciphisa ubushushu.

analgesics Long search, nonsteroidal antiinflammatory kunye arhente antipyretic kunye kwezithandani wenzululwazi prostaglandin amagama wabuyela aspirin. Acetyl acid, kwakunye namachiza amatsha ( "Phenylbutazone" "ibuprofen", "Indomethacin", "Ketoprofen", "Ortofen" "piroxicam" niflumic acid njalo njalo., Woluhlutha ezi mpawu. Apha aspirin wayengekho zilungileyo, kodwa akukho iyeza ayinakuze ithelekiswe naye nsimbi ukuphucula isiphumo iintlungu, bagqiba ukwenza indibanisela iziyobisi, apho isiseko iya kuba yonke aspirin efanayo: ". Asfen", "askofen", "Kofetsil", "Tsitramon", "sedalgin" (ekhuthele kakhulu ).

Acetyl asidi bavumile kunikwa elinye igama - acetic acid. iimpahla zazo zingaphelelanga ntlungu kunye nokuncipha lobushushu. Ngeedosi ephantsi iyakwazi lokuhlambulula igazi. Ngoko kwakucingwa de kutshanje. Noko ke, ukukhanya zonyango emva izifundo kutshanje sesiqale kwamathandabuzo, kube aspirin okungeyongozi ngokwenyani? Yena lo mlomo igazi, kodwa kwangaxeshanye bavimba nokususwa zeBlack (iimveliso inkunkuma) emzimbeni wethu. amachiza ukudumba Non-steroidal ( "Analgin", "ibuprofen" "paracetamol", "aspirin", njalo njalo) Ukwandisa sezintso efferent arteriole, ukunciphisa ekugqibeleni ubungakanani umchamo kwakhiwa. Ifumene ulwelo kwemfuneko ukuba kuyanyanzeleka ukuba ukususa umzimba, nangona kunjalo iqulathe ngakumbi, "likaxakeka" kwamadlala umbilo, "ngokuzisa" kunye ulwelo kunye nobushushu. Sifumana kakuhle, kwaye apho sithathe aspirin. Kwi le ngxaki akuyi kuba ukuthetha, ukuba kuphela kwamadlala umbilo ungakwazi imveliso umlinganiselo ofanayo obuba- nezintso. Kodwa inxalenye ebalulekileyo isiphumo zeBlack imali encinane usekho kuthi, nto leyo ekhokelela ekugqibeleni ngokoyiswa izibilini. Noko ke, asimele lo izoyikiso aspirin kuphela. Ngokufanayo, uza eziqhelekileyo kuthi, yaye ikalika, yaye "Kalinka Malinka," kunye nezinye iiresiphi "Ugogo kaThixo". Ingongoma apha ofuna amadlala umsebenzi sweatshop kwaye isiphumo ezilandelayo.

Ukuchaza intetho ngamanye amazwi ibinzana enkulu: ophethe inkcazelo ubamba impilo. Acetyl acid, nantoni na awuyisebenzisanga (antipyretic, iintlungu okanye "kunye"), kufuneka ukuba isetyenziswe ngononophelo kwaye kuphela ngengcebiso therapist.