"Gleevec" (imatinib): oothixo ixabiso. Apho buyanceda ukuthenga Gleevec?

Antineoplastic (anti-ithumba) arhente "Glivec" i inhibitor ziiprotein tyrosine kinase. Into esebenzayo beziyobisi - imatinib - ofihla iseli proliferation kwi thumba kunye iziphumo sokonakalisa kulawulwa wezintlu iseli (apoptosis), kubandakanywa iiseli wegazi, ezo kwasekwa izigulane leukemia etsolo lymphoblastic kwifomu kwakunye nabo banesifo wegazi myeloid ezingapheliyo.

Kutheni iziyobisi generic "Gleevec" intengo kakhulu eliphantsi?

Ukuze ukuthenga kumachiza ayimfuneko yayingafumaneki ukuba nomonde, kukho imveliso iziyobisi generic - mali, eziveliswa technology iziyobisi zibekwe yaye eyona nto efanayo esebenzayo. Isiphumo lokufumana generic iyafana kwaye ixabiso uhlala ufikelelo olungaphaya. Oku kungenxa yokuba imveliso yayo ayifuni kumenzi okanye uphuhliso iindleko, akukho zindleko zentengiso kunye nokuvavanywa.

iindlela Generic "Gleevec", iveliswayo bumabumela Indian Cipla Ltd., igama lo Imatib. Kwaye ungathenga ngayo kwi website WWW.ONKO24.COM., Ngelo xesha kakhulu ukonga kuthengwa. Ngoko ke, lo philisi "Gleevec" ixabiso eRashiya igcinwa ngaphakathi 73 000 engange. Kwaye ixabiso le eyakhiwayo kwisiza ogama malunga 7320 engange. Uyavuma, umahluko yinto ebalulekileyo.

balawule

Kodwa ngaphambi kokuba ichiza generic "Glivec" kuthenga, kufuneka bavumelane ukusetyenziswa kwayo kunye oyingcali kunye namava unyango izigulane ezinomhlaza. Le umthamo kuthetha bathi ixhomekeke Uxilongo kunye imeko yesigulane.

Ngenxa yoko, kwimeko wegazi ezingapheliyo myeloid (CML) inokwalathelwa njengoko mg 400 no-600 ngosuku. Ukuba oko kuye kwabangela ulwamkelo neutropenia okanye thrombocytopenia, idosi yemihla ngemihla Linyuke ku 800 mg / imini njengoko kuyimfuneko. Loo ukwanda unokubangwa yi ukuqhubeka kwesifo ngalo naliphi ixesha, kwaye kungekho isiphumo ezilindelekileyo emva ikhosi yeenyanga ezi-3 unyango.

Iimpawu ze isicelo

Njengezingxobo "Gleevec" kufuneka ukunxila kanye ngemini uze usele amanzi amaninzi. Ukuze siphephe esiswini, iingcali bacebisa ezithatha ichiza kunye nokutya.

Ukuba isigulane unikwe idosi ubuninzi arhente (800 mg), ngoko ke kungcono ukuba bazohlule babe amathamo-2. Ukuba kuyimfuneko, yaze yangxenga ifuthe lomanyano beziyobisi juice apile okanye emanzini. Ukunqunyanyiswa ngenxa kufuneka basela ngoko nangoko emva kwamalungiselelo.

imiphumela emibi

Ezi ziziphumo ebezingalindelekanga ezivela ekusetyenzisweni "Gleevec" umyalelo lweziyobisi kucetywa kweli phepha, zicwadi kunzima kakhulu ukuqikelela, njengoko kukho kwinkqubo unyango kunye neentlobo ngeentlobo iimpawu ezithile ukuya sifo engundoqo kunye iimpawu yeziphumo ebezingalindelekanga amachiza ziyathathwa ngexesha elifanayo.

Xa nokubuyekezwa, "Glivec 'Wanyamezela kakuhle kakhulu abantu abadala kunye nabantwana. Kodwa ke imiphumela emibi isicelo yayo yajika kakhulu ngobulali ukumodareyitha.

Kaninzi kuyabonakala;

• igazi;
• sorhudo;
• isicaphucaphu, ukuluma ukugabha;
• amahlaba imisipha;
• intlungu izihlunu ndawo;
• intloko ebuhlungu;
• irhashalala phezu komzimba.

oyi

Unyango ezi arhente kufuneka ikhatshwe iimvavanyo rhoqo kwegazi, kwakunye nolawulo umsebenzi kwesibindi, inzuzo ubunzima kunye neemeko zesisu. ingqalelo eyodwa kufuneka inikwe izigulane kunye nesifo sentliziyo kunye nabantwana ukususela abafumana lokugqibela ichiza Ingabangela kubanjwa ukukhula.