I-Lipase i ... Inqanaba le-lipase egazini: isiqhelo

I-Lipase iyi-enzyme yamanzi eyenzileyo enomzimba. Iyakhuthaza i-hydrolysis ye-esters engabonakaliyo, kwaye iphinda ikhuthaze amafutha angathathi hlangothi ukuba atywe, apheliswe kwaye ahlukane.

Umsebenzi oyintloko

I-enzyme lipase kunye ne-bile ikhuthaza ukungcola kwamafutha, kwakunye nama-acids acids. Ithatha inxaxheba ekusebenziseni iivithamini ze-fat-soluble ze-fat, i-D, i-K kwaye ziguqula zibe ngumshushu kunye namandla.

I-Lipase egazini lehlukanisa i-triglycerides (lipids). Ngenxa yoko, ama-acids acids ahanjiswa ngokuthe ngqo kumathishini omzimba.

Ziziphi izitho ezivelisa i-lipase

Emzimbeni womntu, i-enzyme lipase iveliswa:

• Kwi-pancreas;
• Esibindi;
• Emiphakeni;
• Emathumbu.

Ukongeza, i-enzyme ikhiqizwa kwiintsana ezisemlonyeni womlomo ngenxa yeengqungquthela ezikhethekileyo. Abantwana bahlakulela ukuhlanganiswa kwe-lipase yeelwimi, eyenza amafutha obisi.

Iqumrhu ngalinye linika i-enzyme ethile ephula amaqela achazwe ngokucacileyo.

Injongo ye-lipase emzimbeni womntu

Ngoko ke, umsebenzi ogqwesileyo we-lipase kwanoma yiluphi uhlobo kukusetyenziswa kwezixhobo, ukuhlukana kwazo kunye neqhekeza. Kwakhona, le nkunkuma ithatha inxaxheba ekutshintshisweni kwamandla, ikhuthaza ukuxutywa kwe-acids polyunsaturated fatty acids, iivithamini ezithile.

I-enzyme ebaluleke kakhulu i- pancreas. I-Pancreatic lipase yi-enzyme leyo i-lipids ifakwe ngokupheleleyo kunye ngokupheleleyo. Ingena kwi-digestive tract, apho, phantsi kwezenzo ze-colipase, ene-enzyme ye-pancreas, idibanisa ne- bile acid kwaye iguqulwa ibe yifom esebenzayo. I-Pancreatic lipase idlala indima ebalulekileyo - ithetha i-triglycerides (amafutha angathathi hlangothi) zibe zimbini: i-glycerol kunye ne-fatty acids ephezulu.

Ukwahlukana kweentlobo ezahlukeneyo ze-lipase

Njengoko kuphawuliwe ngasentla, iintlobo ezahlukeneyo ze-lipase zidibanisa neentlobo ezithile zee-fat.

I-lipp lipase isebenza neepoprotein ezincinane. Ingumlawuli womxholo weeplasma lipids.

I-gastric lipase ihluthe ioli ye-tributyrin. Iilwimi zithatha inxaxheba ekuqhelweni kwamafutha afumane ubisi lwebele.

Norm kunye nokuphambuka

Kwinqanaba le-lipase ekhoyo kwigazi, umntu unokugweba imeko yomzimba womntu. Ukungaphumeleli kwinqanaba lokunyuka okanye ukuncipha kuvumela oogqirha ukuba bachonge izifo ezinxulumene nesigxathu somzimba. Ngoko ke, ngenxa yezikhalazo zezifo, oogqirha banika uhlalutyo olubanzi. I-Lipase - yintoni na into: ukuqheleka okanye ukuphambuka? Kukho iindlela ezithile eziqhelekileyo.

1. Kubantu abadala, kungakhathaliseki ukuba besini, abaneminyaka eyi-17 ubudala, isalathisi ye-lipase nge-1 milliliter yegazi kufuneka ivela kwiiyunithi eziyi-0 ukuya ku-190.
2. Kubantwana nabaselula, esi sibonakaliso sincinci kwaye ngokuqhelekileyo sifanele sifaneleke kumgama ukusuka kwiiyunithi eziyi-0 ukuya kwezi-130.
3. Ukuba izinga lepascreatic lipase liphandwa, ngoko isisiseko iya kuba iiyunithi ezingama-13-60 ze-enzyme nge-1 ml yegazi. Zonke eziphezulu kunezi zikhombisi, kubonisa ukungasebenzi kwimisebenzi yomzimba.

Ukuba izalathisi zigqithisileyo

Ukuba i-lipase yanda, ngaba kufanelekile ukulila i-alamu? Ewe, eli qiniso kufuneka lihlawulwe ngokugqithiseleyo. Kwaye kuphela ugqirha ngoncedo lweemvavanyo kunye neendlela ezongezelelweyo zokubhalwa kweemviwo kunokukwenza ukuxilongwa ngokuchanekileyo. Emva koko, i-lipase iyinkqubo ye-enzyme ethatha inxaxheba kwiinkqubo ezininzi, kwaye kuphela oyingcali onokukwazi ukuba yiyiphi indima echaphazelekayo.

I-Lipase yanda ngezo zifo:

1. Pancreatitis. Le enzyme iba ngakumbi ngeendlela ezinzulu zesifo, kunye nexesha lokuxhatshazwa kwenkqubo engapheliyo.
2. Biliary colic.
3. Ixinzelelo kwii-pancreas, njengomthetho, ihamba kunye nokukhula okubukhali kwale enzyme.
4. Iiplastiki kwiipascreas.
5. I-gallbladder pathologies engapheliyo inegalelo kumlinganiselo omkhulu we-lipase production.
6. Ubukho be-cyst kwi-pancreas.
7. Ukufakwa kwendawo yokuhamba nge-pancreatic nge-stone okanye isiqhekeza.
8. Cholestasis ye-Intrahepatic.
9. Umqobo okhulayo wamathumbu emathunjini.
10. Peritonitis.
11. Ubungakanani bemathumbu.
12. Izilonda zamathumbu ezisiswini.
13. Ukuguqulwa kwamalungu angaphakathi.
14. I-epidemic parotitis.

Njengoko ubona uluhlu lwezifo apho izinga le-lipase egazini liphakama, likhulu kakhulu. Yongeza kuyo ezininzi izifo ezinxulumene nomzimba emzimbeni ohamba kunye nesifo sikashukela, isifo okanye ukukhuluphala, kunye ne-cirrhosis yesibindi okanye ixesha elide elingenalo ukufumana imichiza, kwaye uluhlu luya kuphinda luphindwe kabini. Kufanelekile ukukhumbula ukuba i-lipase i-enzyme ethatha inxaxheba kwinkqubo yokuxilonga, ngoko ke nayiphi na into inokukhuphaza ukuveliswa kwayo emzimbeni.

Ngoko ke, akufanele unokwenza uhlalutyo ngokwakho, kuphela ngokuhlalutya nokufunda iincwadi zonyango. Ingcali kuphela, kuxhomekeke kwisethi yezinye iinjongo, inokwazi ngokuchanekileyo imbangela yokugula kunye nokuphuhlisa iingcebiso ezichanekileyo kunyango.

Imiba ebalulekileyo

Ngamanye amaxesha i-lipase iqala ukunyuka ngokukhawuleza emva kokuba i-traumas ihlupheke. Ngenxa yokuphuka kwamathambo e- tubular , ukwanda kwe-enzyme egazini kuphawulwa. Kwaye oogqirha bayazi kakuhle oku.

Umgangatho we-lipase ubaluleke kakhulu ukujonga ukuba i-pancreas ichaphazeleka njani. Ukuba amanqanaba egazi le-amylase (i-enzyme ephula umthamo) aphezulu kakhulu, ngoko ugqirha unethemba elikhulu unokufumanisa i-pancreatic pathology.

Ngokukhawuleza ukuba kunokwenzeka ukususa ukuvuvukala kwilungu eligulayo, zombini ezi ziboniso zibuyele eziqhelekileyo. Nangona kunjalo, i-amylase ibuyiselwe ngokukhawuleza. Kodwa i-lipase ixesha elide linokuphakama kuneyona evamile.

Ngelo xesha, inani le-enzyme alinyuswanga ngokukhawuleza. Ukuba i-pancreatitis iqalile, ngokokuqala ngosuku iindidi ze-lipase zisesimeni esivumelekileyo. Nqabile kakhulu bavuka ngokukhawuleza. Ngokuqhelekileyo ngokuhlalutya, lesi sifo senziwa kuphela ngosuku lwesithathu.

Emva kokuqala kwenkqubo yokuvuvukala, izinga eliphezulu le-lipase liyabonwa ukusuka kwiintsuku ezintathu ukuya kwezixhenxe. Kwaye kuphela ke izibonakaliso ziyawa.

Ingqwalasela ingakumbi kufuneka ihlawulwe ukuba izinga le-lipase lidlulileyo ezili-10 okanye ngaphezulu. Oogqirha banokucinga ukuba ezinjalo izikhombisi zibi kakhulu. Kule meko, kufuneka unyango olukhawulezileyo.

Inani elinciphile le-lipase egazini

Umxholo ophezulu we-lipase ubonisa ukungasebenzi kakubi emzimbeni. Kodwa oku kuncitshiswa kwimixholo kubonisa nezifo ezinzulu.

Iqondo eliphantsi le enzyme liyabonwa:

• Ukuba umzimba unesifo esibuhlungu, asikho nje kwisigca esiswini.
• Ukuba umsebenzi we-pancreas unciphise.
• I-cystic fibrosis (okanye enye i- cystic fibrosis). Esi sifo sesifo esiyimfuyo esibuhlungu ngokuphindaphinda, efuna unyango olude. Ivela kwi-lesion pathological of the glands of secret secretion.
• Emva kokuhlinzwa, xa i-pancreas isuswa.
• Ngenxa yokungondleki, xa ukutya kukuqulethe ukutya okunamafutha amaninzi.

Kananjalo, oogqirha baqaphele ukuba ukuba izinga le lipase lide liphantsi, oku kungabonisa ukuba i-pancreatitis idlulele kwifomu engapheliyo.

Ukuba unengxaki ye-metabolism, ngesigxina sesisu, ukubeka iliso kwinqanaba le-lipase egazini kuyimfuneko. Esi sibonakaliso esibalulekileyo esiya kuvumela ukufumana isifo ngexesha kwaye siqale unyango olufike ngexesha.