Ichiza "Chlorpromazine": reviews oogqirha, imiyalelo ukusetyenziswa, ukubunjwa kunye nenkcazo

iziyobisi Antipsychotic - a amachiza psychotropic, leyo eyenzelwe ukuba unyango ukuphazamiseka ngengqondo. Kufuneka kuqatshelwe ukuba igama yemveli kwamachiza ezinjalo - neuroleptics. La machiza ngempumelelo nefuthe iimpawu ezifana iimfeketho zokufeketha, ukukhohlisa, nemibono, wacinga disorder, ukuphazamiseka ngengqondo, ihambo disorder , njalo njalo. D. Faka la machiza kufuneka namava kuphela ugqirha.

Siyobisi ethandwa antipsychotic izenzo "Chlorpromazine". Imiyalelo yokusebenzisa, ixabiso, ncomo, analogs, contra-imbonakaliso kunye iziyobisi thaca ngezantsi.

Ubume, incazelo, uhlobo

Yintoni uhlobo ezendeleyo ichiza "Chlorpromazine" na? Imiyalelo, ukubuyekeza ingxelo ukuba eli chiza okuthengiswa ngohlobo iipilisi sinombala-pink, kwakunye isisombululo ukuba ulawulo efakwa kunye intramuscular. Le into esebenzayo kuthetha idatha chlorpromazine hydrochloride. Kwakhona, ngokuxhomekeke kwifom release ziqulathe ezahlukeneyo extras.

features kwemithi

Yintoni na iziyobisi ephawulekayo "Chlorpromazine"? Imiyalelo yokusebenzisa, iimpendulo zibonisa ukuba le arhente antipsychotic, leyo yi iqela bayo amayeza libhekisela neuroleptics. It has a iqinile, antiemetic kunye neziphumo antihistamine.

Le esisebenza ngayo esi ichiza yemvelaphi phenothiazine. Ukongeza kwezi propati medicament esebenzayo anazo, sine hypothermic buthathaka, antipsychotic, kuyacaca wengingqi, vasodilating kunye neziphumo abangaxhalabisiyo M-anticholinergic.

ukusebenza Antipsychotic zesixhobo iyazalisekiswa ngokubhloka dopamine D _receptors-2 kunye neenkqubo mesolimbic Mesocortical. Ngenxa iimpawu ezinjalo ichiza akwazi ukuphelisa nemibono, iimfeketho zokufeketha kunye nezinye iimpawu ohlonelwayo ngengqondo.

Kufuneka kuqatshelwe kwakhona ukuba "Chlorpromazine", ncomo kuzo zidweliswe ngezantsi, nokuphelisa iindidi ezahlukeneyo lengqondo kukuphazamiseka, ndlongondlongo kunye kunciphisa ubungqongqo yokoyika ingqondo.

okulalisa beziyobisi kuyafikelelwa ngokubhloka kwikhemesti adrenergic reticular ukuba ibekwe brainstem.

iimpawu ichiza

Zeziphi iimpawu ezendeleyo medicament "Chlorpromazine"? Ukuphonononga baxele ukuba eli chiza nefuthe ngxelo imbi kumsebenzi conditioner reflex, buyasikhulula izihlunu skeletal, kunciphisa umsebenzi motor zidityaniswe, kunciphisa uvakalelo kwizinto zemveli kunye ezisuka ngaphandle kunye ingqondo ngokuthe ngcembe. Ukusetyenziswa amathamo ezinkulu ichiza kubangela ukozela kakhulu.

Kuvalwe iindlela i-luvo vagus kwi zesisu phecana kunye dopamine _D2 receptors ibekwe kwindawo aqala emetic kunye ziko libonelela isiphumo antiemetic kweli chiza. Kufuneka kuqatshelwe kanjalo ukuba esi sakhiwo babungena receptors M-cholinergic. Ngaphezu koko, iziphumo zayo libizwa kwaphawulwa ukuba receptors Alpha-adrenergic.

Isenzo beziyobisi

iziyobisi "Chlorpromazine" Zisebenza njani? Ukuphonononga bathi esi sixhobo uyakwazi ukubeka ecaleni ngokupheleleyo neziphumo ezathi zibangelwa epinephrine. nemiphumela yaso hypothermic ngenxa kuvalwe iindlela receptors dopamine ukuba ibekwe ngxenye.

iziyobisi kujongwa kwandisa uxinzelelo lwegazi, izinga intliziyo ukunyuka, kuba isiphumo buthathaka antihistaminic kwaye wavakalisa inyathelo kataleptogennoe, kwaye kucutha permeability beendonga capillary.

Kuba ulawulo intramuscular le medicament ibangela umthomalalisi ngexesha leeyure ¼, yaye emva ulawulo ngomlomo - imizuzu emva 120. ukunyamezelana isigulane sine kwaye iqinile isiphumo senzeka malunga enye ngeveki.

Xa ufumana le iyeza ibe iimpawu zakhe antipsychotic kuba ukusebenza ngomhla 4 okanye 7. Isiphumo therapeutic beziyobisi ithatha malunga neenyanga 2-6.

Le pharmacokinetics beziyobisi

Ngaba "Chlorpromazine" ukusivumela? Ukuphonononga ingxelo ukuba ngomlomo chlorpromazine fast kodwa kwelifunekayo ngokupheleleyo kwinkqubo yokwetyisa. Its lamanani igazi eliyincopho afunyenwe emva 4 h.

Eli chiza ivavanywa kudlula kuqala nge esibindini. Ngoko eyavela egazini emva kulawulo somlomo kuba ngaphantsi kakhulu xi emva ulawulo intramuscular.

Ichiza umzimba esibindini ukuba avela luyeke ukusebenza uze esebenzayo.

Chlorpromazine has a ibhondi eliphezulu kwiiproteni plasma. Yaziwa ngokubanzi kusiwa umzimba umguli, ezendeleyo nge BBB.

Half-ubomi izinto akhutheleyo ichiza malunga nemizuzu engama-30. Ngaloo ndlela ukupheliswa avela kulo ibe elide.

medicament iboniswa ingqalelo kunye umchamo inyongo.

Drug "Chlorpromazine": zikhombisa ukuba ukusetyenziswa

Ukuphonononga baxele ukuba ichiza ngokubanzi kusetyenziswa xa kusenziwa zengqondo. Oku kumiselwe ukunyanga ukuphazamiseka xa umntu ngesifo sengqondo. Kwakhona, eli chiza isetyenziswa ezondeleyo ukugula ngengqondo, etsolo ithi bazikhohlisa, uchulumanco hypomanic, sokulibala, psychopathy, ukugula ngengqondo, ixhala, uloyiko nexhala.

Ukongeza iimeko ezidweliswe izinto ezibonisa ukuba ukusetyenziswa kwale echiza: hiccups ziqhu, ukugula ngengqondo utywala, ukugabha lawuleki yaye isicaphucaphu kakhulu. Ukuba kukho intlungu ichiza kuphucula ifuthe analgesics.

Kufuneka kuqatshelwe ukuba indlela eyabelwe kuqwalaselwa izifo ezithi zihamba ngokwanda ilizwi dystrophy, ngqi (njengoko Combination Therapy kubanjiswene barbiturates) kwaye emva ukuphazamiseka ezahlukileyo ejikeleza lobuchopho.

Hayi kudala, eli chiza sisetyenziselwa emzimbeni ngumntu yabhalwa imixube lytic. Xa anesthesiology olu nyango rhoqo ezimiselweyo umthomalalisi kunye zomzimba potentiation jikelele.

Xa practice dermatological "Chlorpromazine" (iimpendulo ezigulane malunga ichiza ikakhulu nesimilo) ezisetyenziswa sokudlathuka kweenwele dermatoses. Ukongezelela, oko ungasetyenziswa ukunyanga porphyria uphawu ahlekise.

Izimo

Kwezinye iimeko, awusosimiselo antipsychotic "Chlorpromazine"? Izimvo oogqirha ingxelo ukuba esi sixhobo alisetyenziswa States comatose kuwo nawuphi na umthombo, kwakunye izigulane kwingcinezelo kakhulu e-nervous system, isifo kakhulu intliziyo ukubanyamezela nemithambo ukuya into esebenzayo, isifo ngcembe ingqondo kunye nohlobo spinal lwenkqubo yemfundo ingqondo, izilonda sisilonda le iphecana zesisu nasebudeni webele ibele.

Ngenxa umngcipheko ophezulu reactions hepatotoxic, oko kuthetha emiselweyo ngononophelo lirejistarisha butywala. Kunjalo ke naxa ufuna umhlaza webele, dyscrasias igazi, hyperplasia le prostate, glaucoma, ivaliwe-form, isifo Parkinson kaThixo, sokuwa, myxedema, ukugabha, cachexia, Reye syndrome kunye nabantu abadala.

Drug "Chlorpromazine": imiyalelo yokusebenzisa

Tablets zokulinganisela leyo thaca apha, ezisetyenziswa xa kusenziwa zengqondo ekuqaliseni ngemihla oyidlayo ilingana 25-100 mg. Le mali ithi yahlulwe 1-4 nasebusuku. Ekuhambeni kwexesha, ukunyusa ithamo zonke iintsuku ezine 25 okanye 50 mg ukuze kufikelelwe isiphumo ezinqwenelekayo.

Nexhala othululwayo kweziyobisi preoperatively esebenzayo iiyure 2-3.

Ithamo eliphezulu enye yale arhente 300 mg, kwaye yemihla ngemihla - 1,5 g

Ngokumalunga isisombululo, oko ilungiselelwayo yegazi okanye intramuscularly. umthamo zokuqala yale ichiza 25-50 mg.

Phambi ulawulo ichiza kwaye bungxengwe 2.5 ml sisombululo sodium chloride okanye procaine. Iinaliti ukwenza inaliti enzulu intramuscular.

Ithamo eliphezulu enye yale arhente yi 150 mg kwaye yemihla ngemihla - 1 g Njengoko yolawulo efakwa, ezi amaxabiso kunxibelelana 100 no 250 mg.

imiphumela izigelekeqe

Ababuthela naziphi na iziphumo ebezingalindelekanga "Chlorpromazine" (tablets)? Ukuphonononga baxele ukuba nisaqala unyango olu nyango kungabangela umlomo owomileyo, paresis yokuhlala, frigidity, ukozela ukwanda, ukuqhina, zokulala, isiyezi, ukutya kakuhle, tachycardia, wavakalisa uhlobo hypotension intolerance, ukugcinwa wokuchama, kunciphise amandla, nokwaliwa awe uxinzelelo lwegazi.

unyango elide nalo eli chiza kubangela imisipha uphathwe intamo kunye nolwimi, neuroleptic ngumkhuba uxinzelelo Akinetes-engqongqo, ukuphazamiseka extrapyramidal, amenorrhea, akathisia, asabela ulibele zizinto ezahlukeneyo, hypercoagulability, ukugabha, utshintsho ngengqondo, arrhythmia kwentliziyo, nombala ulusu, inhibition ithambo umongo hematopoiesis , gynecomastia, senyongo cholestatic, galactorrhea, giperplolaktinemiyu, oliguria, urhudo, kwaye neuroleptic amabi syndrome. Nge efakwa phlebitis ukumnika ibunjiwe intramuscular - lingene.

izincomo ezithile

Therapy le sixhobo kufuna ulawulo ngononophelo uxinzelelo lwegazi, ukubetha, ukusebenza izintso wesibindi.

Eli chiza ingenza photosensitivity, kwaye ngoko ngexesha kokungeniswa Kucetyiswa ukuba sesichengeni.

Analogs neendleko

Ixabiso le iyeza kuxhomekeke kwifom release. Packaging of ezineengqayi 10 kuthengelwa engange-60, lo gama inani efanayo amacwecwe imalunga 150 engange.

Ngu analogue kweli chiza ziquka "Chlorpromazine hydrochloride" yaye "Tisercinum".

reviews

Ngokutsho kweengcali Ndaziqiqa medicament ngandlela enamandla antipsychotic, ngokususa zonke iimpawu lengqondo ukuphazamiseka. Nakuba kunjalo, kufanele kuqatshelwe ukuba oku kuthetha review indalo ezahlukeneyo.

Ezinye izigulane zithi ukuba eli chiza iyasebenza-Alzheimer izifo, schizophrenia, ukugula ngengqondo, sokuwa, kunye kakuhle nokuphelisa unxunguphalo nokuphazamiseka. Abanye abathengi bakholelwa ukuba iyeza ingqalelo kuphakamisa uphuhliso sokuwa, ngesandla shake-, iingxaki ezahlukeneyo ubuntu kunye nobuthongo karhulumente ngokugqithiseleyo.

Nakowuphi na umzekelo, oku iyeza kufuneka isetyenziswe kuphela njengoko kuchaziwe phantsi kweliso logqirha khona.