Ichiza "famotidine": nokubuyekezwa kumagqirha ekusetyenzisweni

hyperacidity esiswini ikhuthaza nje ukubonakala mizwa ekhathazayo, kodwa ke uphuhliso kwezifo ezifana kukhukuliseko kunye nezilonda mucosal. Ngoko ke, xa uphawu yokuqala zokutenxa enjalo kufuneka ngoko nangoko udibane nogqirha, a gastroenterologist.

Inzuzo wavelisa namhlanje amachiza ezininzi ezahlukeneyo zinqanda secretion of zehydrochloric acid. Eyona ndlela kakhulu kwaye ayafikeleleka ziquka amayeza "famotidine". Izimvo oogqirha bathi amayeza wona aya thaca ngezantsi.

ifomu ukukhululwa, ukupakisha, inkcazo kunye nokwakheka

Ukulungiswa "of famotidine" ikhutshwa ngohlobo ngeengqalutye ezincinane. Ba setyhula kwaye lenticular imilo, nesikhumba emthubi okanye mdaka.

Le esisebenza yale arhente yi famotidine. Ngaphandle kwalo, imveliso iqulathe amacandelo abangabancedani magnesium stearate, umbona starch, microcrystalline kwincindi, lesilicon dioxide, talc, kunye sodium croscarmellose.

Malunga iqokobhe, iquka hypromellose, talc, Macrogol 6000, titanium dioxide (E171) kunye brown intsimbi oxide ebala.

Drug "famotidine" ifoto ukuba thaca kweli nqaku ayafumaneka Imiqulu blister, leyo iqulethwe ezibhokisini ephepheni.

Pharmacology of nechiza elichasene-isilonda

Yintoni na iziyobisi ephawulekayo "famotidine"? Ukuphonononga baxele ukuba kukho ochasene lokhuphiswano histamine. Eziphembelela histamine H2-receptors iiseli Parietal, lunciphisa secretion ka zehydrochloric acid, wayenga zizinto ezahlukeneyo. Kwakhona inciphise imveliso Uhlobo Lokuqala. Xa oku kusenzeka ukuba ongaphantsi kangangoko secretion inhibition yabangela pepsinogen.

Ukwamkela ichiza uphononongwayo akusenzi amanqanaba gastrin egazini. Ubude wesenzo phezu yedosi-abaxhomekeke isicelo esisodwa kwaye ziiyure 12-25.

Le kinetics ka iziyobisi

Apho kukufakwa ichiza 'famotidine "? Ukuphonononga bathi emva ulawulo yomlomo beziyobisi ako ngokukhawuleza ukusuka phecana zesisu. Ngaphezu koko, eyavela incopho kuyafikelelwa egazini iiyure 1-3.

Unxibelelwano plasma protein yi 17-20%. Iyeza salawo ngobisi lwebele kwaye ingene nge njengomqobo placental.

Malunga nama-30-37% of famotidine umzimba esibindini. imveliso yawo salawo nge nezintso.

ubungqina

Yintoni ebonisa ichiza "famotidine"? Ukusetyenziswa kwale arhente kunempembelelo entle imeko wokugaya kwi:

• gastroduodenitis ilunga;
• isilonda nothintelo ukwenzeka kwayo;
• ukuqunjelwa esebenza ;
• lingaze kunye stress isilonda;
• reflux esophagitis;
• adenomatosis ezidalwe multiple;
• syndrome Zollinger-Ellison;
• mastocytosis systemic;
• uthintelo kokuwela of ukopha kwixesha postoperative;
• Prevention of ngeminqweno juice esiswini kubantu abafumana utyando phantsi zomzimba ngokubanzi (kunye mendelson kaThixo syndrome) ;
• ukuthintelwa yokulangazelela pneumonitis;
• nge ukuqunjelwa retrosternal okanye intlungu epigastric ezenzeka ebusuku okanye emva kwesidlo.

Izimo ukufumana iipilisi anti-isilonda

Xa kufuneka usebenzise ipilisi "famotidine"? Ukuphonononga ichaze ukuba Izimo kule echiza lithi zilandelayo:

• lwebele;
• nokukhulelwa;
• kweminyaka iminyaka emithathu ubunzima umzimba ukuya kwi-20 kg;
• hypersensitivity ku famotidine kunye nezinye blocker of histamine H2-receptor.

Ngononophelo kakhulu na iyeza esimiselweyo omzimba, isibindi okanye ukusilela kwezintso ebantwaneni kunye ukuqina Encephalopathy kwesibindi (portosystemic).

Kufuneke njani "famotidine" icwecwe?

Ukuphonononga baxele ukuba ichiza athathwa ngomlomo, ngaphandle ukuhlafuna.

Abantu abadala kunye nezilonda le wokugaya kunye gastroduodenitis ilunga amisele mg-20 kabini ngemini. Ukuba oyifunayo, idosi yemihla ngemihla angandiswa ku-80 okanye 160 mg. Olu nyango kufuneka kuthabatha iiveki ubuncinane 4-8.

Phambi ukuqunjelwa, ihlobene nokonyuka secretion esiswini, izigulane elawulwa-20 mg kweziyobisi kanye ngemini.

Kuthintelo lwe kwethumba likakade ukusetyenziswa kweziyobisi 20 mg yonke imihla ebusuku.

Xa Zollinger-Ellison syndrome idosi beziyobisi kunye nexesha izifundo unyango zibekwe ngamnye. Ithamo yokuqala medicament xa uphethwe ngokuqhelekileyo-20 mg. Oku kwenziwa qho kwiiyure ezi-6. Ukuba kuyimfuneko, oko kwandiswa ukuya mg 160.

Xa refpyuks esophagitis ukusetyenziswa kweziyobisi 20-40 mg kabini ngosuku ezintandathu - iiveki ezilishumi elinambini.

Abantwana abangaphezulu kweminyaka emithathu kwethumba kunye reflux esophagitis namayeza emiselweyo ngomlinganiselo 2 mg / kg ngosuku.

imiphumela emibi

Yintoni iziphumo ebezingalindelekanga ezendeleyo i "famotidine" echiza? Izimvo kumagqirha zibonisa indlela kulandelayo:

• umlomo owomileyo, ukudinwa, ukugabha, isiyezi, iintlungu esiswini, ukozela, ukuqhina, ukuphazamiseka namdla, uvalo, umsebenzi ukwanda kwe-enzyme zesibindi, irhashalala, i-pancreatitis oyingozi;
• ukudideka, bradycardia, nemibono, vasculitis, eDayalayo;
• arrhythmia, isikhumba owomileyo, kunciphise uxinzelelo lwegazi, AV-block;
• alopecia, leukopenia, amaqhakuva vulgaris, ukungaboni, ukudumba antionevrotichesky, ukurhawuzelela, agranulocytosis, bronchospasm;
• intloko, isicaphucaphu, sokulibala, ixhala, ukuqumba, ukuduma, urhudo, ukudakumba, hepatitis, ukugula ngengqondo, paresis zokuhlala;
• mothuko anaphylactic, hypoplasia, izenzo hypersensitivity;
• thrombocytopenia, amenorrhea, pancytopenia, hyperprolactinemia, aplasia le umongo;
• gynecomastia, namandla, ifiva, iintlungu kwamalunga;
• yehle yobuntu, iintlungu kwezihlunu, ukunyuka kwamazinga urea egazini.

reviews

Iingcali zithi ichiza "famotidine" ayikho iarhente isebenzayo anti-isilonda. Ngaphandle koku, oku kudla kakhulu isetyenziswa kunyango lwezifo zesisu.

Ke ukuba izigulane, bexabana ukuba ngemihla okuqala onyango ichiza uziphethe kakuhle kakhulu. Kamva, kuthiwa kupheliswa.