Iiprotheyini kumchamo. Izizathu zinokuhluka

Umxholo oqhelekileyo kumchamo weprotheni kukukho kwinqanaba leproylene ye-whey, ehlongozwayo ngeendonga ze-capillaries ezintso. Ngokuqhelekileyo isibonakaliso akufanele sidlule i-0.002 g / l, ukuba udlulisa uhlalutyo oluqhelekileyo ekuseni. Ngomhla we-50-150 mg weprotein kwi-urine yinto evamile. Kodwa iphrotheni yayo engaphezulu kunye nephakamileyo kumchamo, izizathu zokungaqhelekanga kufuneka zihlolisiswe ngenyango kwiklinikhi, ngakumbi ukuba iprotheni iphakanyisiwe kumfazi okhulelwe.

Inkqubo yenkqubo, apho kukho ukwanda kwindleko yeprotheni eyadluliselwa kumgca we-basal wezintso, inzima ngokwaneleyo. I-Hyaluronidase ithatha inxaxheba kuyo. Le enzyme, kunye neminye imisebenzi, ifake i-mucopolysaccharides kwi-serum yegazi. Ukwanda komsebenzi walo kwandisa ukugqithiswa kweendonga ze-capillaries kunye nokuphelelwa komlenze, oqala ukudlula kwiimodeli zeprotheni.

Xa kukho iprotheni kumchamo, izizathu zinokunyaniseka (inkunzi) kunye nobuxoki (extrarenal). Ubuqhetseba okanye inyaniso yesifo, ukuba yinkqubo yesikhashana okanye engapheliyo inokusekwa kuphela oogqirha.

Kutheni iprotheni emcinini

Isiseko sokuvelisa amaprotheni emzimbeni womntu ngumthombo wolwazi. Kukho kwiijenge zomntu ngendlela ekhowudiweyo. Inkqubo ehamba phambili yokuthutha, i-synthesis, ukubuyiselwa kwakhona kunye nokulandelelaniswa kwezinye zezi nkqubo kukhokelela ekukholeni nokuchaneka kweeprotheni emzimbeni. Ukugqithiswa kwesinye sezigaba zenkqutyana edibeneyo yenguqu elandelelanayo yokuguqulwa kwamaprotheni kumandla, alawulayo kwaye aququzelele umsebenzi wawo, ekhokelela ekubonakala kwiprotheyini kumchamo.

Izizathu zeso sifo zingabangelwa yimicimbi yesikhashana okanye ezinzile, ebangelwa yintlupheko yomsebenzi emzimbeni. Akunakwenzeka ukunika impendulo epheleleyo kumbuzo wokuba kutheni iprotheni esemzimbeni, ngaphandle kokuqhuba iimviwo ezipheleleyo.

Ukwanda kwinqanaba leprotheni kunokubangela ukuphazamiseka kwemijelo ye-renal:

• Ama-Anomali ekuphuhlisweni kwe-veal venin;
• Utshintsho ngenxa yeziphumo ezinobungozi kwiindonga zama-capillary ezintso;
• Sitshintshe ngaphantsi kwefuthe leziyobisi (ukungamkelekanga okanye ukungamkelekanga ukufumana);
• Ukuphazamiseka kwimisebenzi yamathambo e-renal;
• Izifo kunye neentsholongwane zomzimba.

Ukuba iprotheni emcinesini ikhona ixesha elide, izimbangela zingabakho kwizifo ezahlukahlukeneyo zomzimba, ezifana nezifo zendlela yokugaya inyama, iifom ezinzima ze-anemia, umphumo wokutshisa, ukulimala, ukuxhomekeka kwegazi, ukunyamekela ngokomzimba okanye imvakalelo yangemvelaphi. Kule meko, esi sifo sisisigxina, kunye nokupheliswa kwesizathu, iprotheni ishiya umchamo.

Isigxina (okanye ixesha elide) ubukho beeprotheyini kumchamo (proteinuria) kubonisa ukuba isifo sesifo kwakhona kwimeko xa kungekho zibonakaliso.

Izizathu ezinokwenzeka zokubonakala kweprotheni kumchamo

• Izifo ze-glomerulonephritis;
• I-Glomerulosclerosis ngenxa yesifo sikashukela;
• I-Thrombosis kwiinqanawa zeentso;
• Ubuninzi bezintso eziqhubekayo;
• Urolithiasis nabanye.

Ukuxilongwa nokunyangwa

Isiqhelo seprotheni kumchamo umxholo wayo awukho ngaphezu kwe-50 ukuya kwi-150 mg / ngosuku. Inani leprotheni lifumaneka lula. Ngokuqhelekileyo oku kufunyenwe ngokudlula uvavanyo lomchamo. Ngethuba lemini, umchamo uqokelelwa yindlela ethile. Uhlalutyo luphindaphindwa ukuze kugwenywe umba wendawo, ongatshintsha umfanekiso wezinto eziqokelelweyo.

Ukuze ulawule ithuba lokudlulisa iimvavanyo, gcina izitya zihlambuluke kwaye uhlambe ngokupheleleyo i-genitalia yangaphandle. Ukongeza kwiimvavanyo eziqhelekileyo zomchamo, i- electron microscopy yeentso ingenziwa ukwenzela ukukhangela ukungaqhelekanga kwimbumba yesiseko, ukwandiswa kwinani lamapolisa nobukhulu bayo.

Ingqwalasela ngokukodwa ihlawulwa kwinqanaba leprotheni kumchamo wabasetyhini abakhulelweyo, kuba umsebenzi wezintso uyanzima ngumbumba okhulayo kunye nokunyusa uxinzelelo kwizinto eziphilayo kunye neentso ngokukodwa. Isiqhelo sinciphise kwaye akufanele sibe ngaphezu kwe-0.14 g / l (kwifom yeesayili).

Ukunyangwa kwesifo esiyinkimbinkimbi ehambelana nomsebenzi ongasondelanga (okanye esinye isifo sesifo esifumene ngabagqirha) singenziwa kuphela kwiklinikhi.