Indlela kunye nemiyalelo yokusebenzisa "Loraksona". Analogs nokubuyekeza

Yintoni lo neziyobisi "Lorakson 500"? Imiyalelo zokusetyenziswa, iimpawu zesixhobo, ngokunjalo njengesalathiso wayo, imilo, ukwakhiwa kunye analogs kuxoxwe ngazo ngezantsi.

Packaging, imilo, ukwakhiwa ichiza

Yiyiphi imilo uphawu kuba amayeza ayikhumbule? yemiyalezo Yintoni le bill ithi? "Lorakson" i ngumgubo crystalline amhlophe okanye tyheli kancinane, yenzelwe ukulungiselela isisombululo efakwa okanye intramuscular. Ukubunjwa medicament iquka esisebenza ezifana ceftriaxone. Oku thaca ngokohlobo ityuwa walo sodium.

Kwakhona, i "Lorakson" yemiyalezo lweziyobisi uqulathwe isipha wekhadibodi luquka kwisinyibilkisi njengoko amanzi ngenaliti.

Amalungiselelo isifundo evela nengqayi iglasi ml-10 ezo zingafakwa kwiibhokisi amaphepha (ukuba ithengiswe okanye ngaphandle kuphela).

Imithi Pharmaceutical Products

Yintoni na ichiza ngasentla? Yiyiphi inkcazelo iqulethe imiyalelo yokusebenzisa? "Lorakson" - i-zintsholongwane (cephalosporin) abasisizukulwana sabo sesithathu, elungiselelwe ulawulo parenteral. It has isenzo bactericidal.

Ngenxa ukukwazi zinqanda Yindibanisela inwebu iseli ye ichiza abangaphangeliyo ukukhula ezininzi iintsholongwane ezimbi-Igram kunye Igram-HIV.

Ngokutsho kweengcali, ceftriaxone ubonisa uzinzo ethile nxamnye beta-lactamase (penicillinase, cephalosporinase), nto leyo ziveliswa gciwane kakhulu.

Kinetics yemithi

Indlela Yokuphatha leli imveliso emzimbeni womntu? Yintoni le uthi imiyalelo ehamba ukusetyenziswa? "Lorakson" ngolawulo parenteral yi kakuhle kuzo phantse zonke izicwili kunye neencindi zomzimba.

Kunye nokubandakanywa efakwa of ceftriaxone kubengezele pretty ngokukhawuleza kwi kulwelo Embi, apho iimpawu zayo antibacterial zigcinwa imini yonke.

Kufuneka kuqatshelwe kwakhona ukuba icandelo esebenzayo yomenzeli reversibly nakanjani ukuya albumin. Ngenxa umxholo encinane kubemi fluid Embi, uyazikhomba beziyobisi kuso ngaphezulu kancinane kwi-serum.

Ziziphi ngokoMthetho ichiza livela isigulana? Oko ikuthethayo ngalo imiyalelo ukusetyenziswa? "Lorakson» ogama ukwakheka sele kukhe kwatshiwo ngentla apha, iyavezwa iiyure 8 (kunye enyongweni kunye nomchamo). Kufuneka kuqatshelwe ukuba phantsi kwempembelelo le flora emathunjini of an element esebenzayo kwisixhobo utshintshwa ukuba metabolite opholileyo.

Xa ezisanda kuzalwa, isiqingatha-ubomi kucingwa ichiza eziyi-8, kunye abadala (70 iminyaka), eli xesha kukuphinda-2 ngaphezulu.

Le kinetics amachiza kwiimeko ezizodwa

Xa ezizuzwa inkqubo kwezintso kunye ezimbi kwesibindi abantu abadala abantu pharmacokinetics of ceftriaxone cishe ingaguqukanga, ixesha isiqingatha-ubomi elide akuyomfuneko.

Xa umsebenzi kidney kuya kucutheke kakhulu, nokuphelisa beziyobisi lwenzeka ubukhulu becala kunye inyongo; kodwa ukuba ezonakeleyo kwesibindi, lo ceftriaxone efunyenwe ikakhulu nge nezintso.

Kwiintsana kunye nabantwana abasabhadazayo nangokurhala le meninges le medicament kusichukumisa kwi ulwelo lwe-cerebrospinal. Xa abadala kunye meningitis emva kweeyure 5-25 emva ulawulo kwindawo umthamo ceftriaxone 50 mg / ubunzima bomzimba izihlandlo eziliqela kg eyavela lugqithe MIC, nto leyo efunekayo ukuze kwezithandani iintsholongwane ezibangela izifo.

ubungqina

ukuba ndenze ntoni nini kunye isitofu iziyobisi "Lorakson 500"? Imiyalelo yokusebenzisa (iinaliti kufuneka anikwe kuphela ukuba ugqirha onamava) uthi ukuba ichiza yenzelwe ukunyanga izifo ezosulelayo kunye ukudumba ezibangelwa iintsholongwane ingqalelo ichiza. Ngoko ke, eli lisetyenziswe:

• meningitis;
• izifo Kwiphecana eliphezulu nokuphefumla;
• nokudumba;
• izifo womchamo nezintso;
• izifo kwinkqubo zokuzala (kubandakanywa: ukuvuza ngaphantsi);
• izifo esiswini (kuqukwa izifo yokukrala emathunjini, peritonitis, isifo iphecana biliary);
• usulelo lwesikhumba;
• usulelo lwe iphecana ngokuphefumla (kuquka pneumonia);
• izifo, tissue edibeneyo namathambo;
• izifo kubantu kunye nezifo base-.

Kwakhona, indlela abanokuthathelwa ingqalelo eboniswe nokuthintela amanxeba ezosulelayo kwixesha postoperative.

Uvala ukuqashwa

Ingaba kukho naziphi na Izimo iziyobisi zikhankanywe apha? Oko ikutshoyo imiyalelo ezihamba ukusetyenziswa? "Lorakson" okukhomba ezithe ezidweliswe ngasentla, kufuneka imiselwe kwakhona kwezi meko zilandelayo:

• ngomonde hypersensitivity ukuya penicillins kunye cephalosporins;
• kwithuba leenyanga ezintathu yokuqala yokukhulelwa.

Ekubeni isilumkiso le iyeza kuyacetyiswa kubantu abanesifo sesibindi, ukudumba kunye enteritis. Kwakhona, isilumkiso kufuneka lusetyenziswe xa NUC, hyperbilirubinemia kwi kubelekwa kule trimesters ezimbini zokugqibela zokukhulelwa, iintsana ngaphambi kwexesha kunye nokuncancisa.

Imiyalelo yokusebenzisa

"Lorakson" elawulwa kwizigulana yegazi okanye intramuscularly. I-avareji idosi yemihla ngemihla ichiza kubantu abadala kunye nabantwana ukususela kwiminyaka eli-12 ubudala 1-2 g kanye yonke imihla (qho kwiiyure ezingama-24).

Kwiimeko kakhulu, ngokunjalo nezifo zibangelwa ngamagciwane abangaxhalabisiyo sensitive, idosi yemihla ngemihla yale arhente ukuze kwandiswe ku-4 g

abantwana olulele ekuqhubeni ichiza 1 ixesha ngosuku kucetyiswa idosi zilandelayo: 20-50 mg / kg (ukuya kwiiveki ezi-2 ubudala).

Baby abasafunda ukuhamba nabantwana ukuya kwiminyaka-12, ithamo ngosuku kufuneka 20-75 mg / kg. Abafikisayo kunye ubunzima bomzimba-50 kg medicament iidosi yaphathwa abadala.

Ubude unyango ngale ndlela kuxhomekeke sifo.

Imibandela ekulungiseleleni izisombululo

Indlela yokulungisa isisombululo iziyobisi? yemiyalezo Yintoni le bill ithi? "Lorakson" ifomu release ethe uchazwe apha ngasentla, ngokuba inaliti intramuscular kufuneka axutywe namanzi (1 g) ngo-3.5 ml-1% - nesisombululo lidocaine, uze ungene nzulu esihlunwini gluteal.

Ukuze alungiselele ekuqulunqweni ukuba isitofu efakwa, 1 g na umgubo kufuneka exutywe 10 ml yamanzi Yek (wawuqalekisa). Isisombululo yokugqibela kufuneka ngokucotha kuqaliswa emthanjeni (imizuzu 4).

Kuba nokubandakanywa efakwa-2 g beziyobisi efunekayo ukuze inyibilike ml 40 isisombululo (umz, sodium chloride, dextrose okanye fructose), ukhululekile calcium. Le ukumnika kufuneka wenziwe iyure ubuncinane isiqingatha.

Izenzakalo by-lomsebenzi

Ngaba kwinkcaso sisombululo iziyobisi "Lorakson"? Imiyalelo yokusebenzisa (iinaliti kufuneka kwenziwe kuphela esibhedlele) uthi ukuba kwimeko usebenzisa amayeza isigulane angase:

• isicaphucaphu, leukopenia nokugabha, granulocytopenia, urhudo, hypocoagulation, ukuqhina, igazi hemolytic, flatulence, lymphopenia;
• iintlungu esiswini, phlebitis, incasa ukuphazamiseka, nezazo Kwangale, stomatitis, urticaria, glossitis, neutropenia;
• enterocolitis pseudomembranous, nokungena nokuthantamisa kwindawo wolawulo intramuscular, umsebenzi isibindi kakuhle;
• kakuhle umsebenzi kwezintso, goiter, thrombocytosis, glycosuria, thrombocytopenia, oliguria, irhashalala, azotemia, bronchospasm;
• ukwanda urea egazini, eosinophilia, hypercreatininemia, erythema polymorphic, cylinduria, epistaxis, hematuria, superinfection, anuria;
• fever, ukugula serum, ifiva, angioedema, pruritus, isiyezi, ukothuka anaphylactic, candidiasis, intloko ebuhlungu.

Cooperation namacala libanda

Libanda kweemali wabonakalaliswa isiyezi, intloko ebuhlungu, paresthesia, unditsho, Encephalopathy okanye ukuba khokhoma. Ukuphelisa la ukusebenzisa unyango kwangumqondiso, yaye nokuxhasa imisebenzi ebalulekileyo umzimba.

unyango ngaxeshanye kunye ceftriaxone kunye aminoglycosides kwandisa umsebenzi wabo antibacterial. Ukuze kuthintelwe isiphumo enetyhefu kwezi arhente lwenziwa ngamaxesha angafaniyo kwiindawo ezahlukeneyo.

Used in "Loraksona" inhibitors zegazi udibaniso enxuseneyo kunye NSAIDs kukho ingozi ephezulu ukopha.

Xa ufumana i "ngokwenzekayo" womchamo, kukho umngcipheko omkhulu nephrotoxicity.

Kujongwa amayeza akuvumelani ethanol, njengoko olu dibaniso kubangela isicaphucaphu kakhulu, ziba kummandla epigastric, ukugabha, ukuba nesifuthufuthu, ukuncitshiswa uxinzelelo lwegazi kunye tachycardia.

Akuvunyelwe ngokungqongqo ukuchwetheza kwenye isirinji ceftriaxone kunye nezinye antibiotics.

amachiza afanayo kunye nengxelo namayeza

Ngoku uyazi ukuba i "Lorakson". Imiyalelo yokusebenzisa, ithetha analogs kuxoxwa ngazo kweli nqaku.

Yintoni indawo amayeza? Kuba amachiza afanayo iingcali ingqalelo ezi zinto zilandelayo: "Ceftriaxone-Promed" "Ceftriaxone-ELF," "Tsefogram", "Tsefson" "Ceftriaxone-Protekh" "Ceftriaxone-Dzhodas", "Tseftriabol", "Tsefatrin".

Ngokutsho iimpendulo lezigulane, kaninzi yenza indlela abaye asetyenziselwa ukunyanga izifo zangentla ezihlasela zosulele ngokuphefumla kunye nosulelo phecana zokuphefumla. Ukuhlaziya imiyalezo yabo, singakwazi singatsho wesenzo okukhawulezayo kunye nokusebenza eliphezulu. Kufuneka kuqatshelwe ukuba xa besebenzisa eli chiza kwezinye izigulane kwakukho iziphumo ebezingalindelekanga minor ezingafuni ukupheliswa unyango.