"Komfoderm": imiyalelo ukusetyenziswa, inkcazo, ukwakheka, analogs kunye nohlolo

Yintoni na oyaziyo ukulungiselela ezifana 'Komfoderm "? Imiyalelo yokusebenzisa, ixabiso, ncomo, kwaye analogs lweempawu jikelele kweli chiza ezaziwa ezimbalwa. Ngenxa yoko, kweli nqaku, siye sagqiba ukunika yonke ingcaciso malunga namayeza.

IFomu, ukwakheka kunye nenkcazo

Ukulungiselela "Komfoderm", imiyalelo zokusetyenziswa ichazwa kamva, ekuveliseni ngendlela cream emhlophe kunye ivumba (mhlawumbi ngaphandle kwaye ube ithinti cream).

Amacandelo esebenzayo yale arhente isicelo mlonyeni na atseponat methylprednisolone kunye urea. Kwakhona kwamafutha amayeza na izithako abancedisayo ezithi thaca neparafini elulwelo, propylene ethers, polysorbate 80, carbomer interpolymer (uhlobo A), trometamol, metipparagidroksibenzoata kunye namanzi okuhlamba.

amayeza

Yintoni na ichiza lobulali "Komfoderm" (cream)? Imiyalelo yokusebenzisa ingxelo ukuba glucocorticosteroid kunye nearhente keratolytic ngaxeshanye. wesenzo kungenxa awohluke yeekhomponenti zifakiwe kumafa yayo. Cinga ngokubanzi iipropati zabo.

Methylprednisolone aceponate - oku non-halogenated steroid zokwenziwa. Ngokuba ukusetyenziswa ngaphandle, ikwazi abathintela reactions ulusu komzimba kunye ukudumba kwakunye ngayo ezi zinto zinxulumene ukwanda kwengeniso. kuzichanaba kukhokelela ekuncipheni ebalulekileyo ngemiqondiso kwinjongo ukudumba (erythema, nokudumba, hlala) kunye njengokungathi luluvo (ukurhawuzelela, ukutyabuka, iintlungu, njalo njalo).

Asinako ukuba isicelo weli kwi idosi abawacebisayo neziphumo zayo systemic emzimbeni womntu engephi.

Emva kwethuba elide kwaye ngokuphindaphindiweyo methylprednisolone aceponate kwi imiphezulu ulusu enkulu (40-60%), kwakunye nokubekwa layo phantsi zokubopha occlusive kwizigulane nezitenxo anayenza kwi adrenal, kuquka amanqanaba cortisol lingatshitshi.

Le into ekuthethwa uyakwazi ubopheleleke receptors glucocorticoid intracellular, ebangela iintlobo yeziphumo eziphilayo. Ingakumbi, le nkqubo kukhokelela ngemichiza induction macrocortin yokuqaphela. Kule ezilawulayo release samva acid CD kwaye ukuyilwa yabalamli ukudumba ezifana leukotrienes kunye prostaglandins.

Yiyiphi indima edlalwe ekulungiseleleni urea "Komfoderm"? Imiyalelo yokusebenzisa ithi eli candelo lineziphumo hydrating kunye keratolytic. Sibopha amanzi, ngokwenjenjalo aqale le corneum ezinawo ukhuthaza isikhumba.

Ngaphandle inyathelo keratolytic, urea kunye nomsebenzi nemiboniso proteolytic.

kinetics

Ngaba cream ako, "Komfoderm"? Imiyalelo yokusebenzisa bathi emva kokuba isicelo aceponate isixhobo methylprednisolone hydrolyzes phantse nangoko kule dermis kunye sangaphandle.

I esebenzayo kakhulu kunye metabolite eziyintloko ondoqo 6alfa-imethyl-prednisolone 17-propionate.

The degree of dermal kukufakwa ichiza kuxhomekeke kwimeko igqalwa integument yoluntu kunye indlela yokusetyenziswa (kunye okanye ngaphandle occlusive bandage).

kukufakwa Percutaneous beziyobisi abantu ukhwekhwe kunye atopic dermatitis izixa malunga 2.5%, nto leyo ngaphezu kancinane izinga kwi amavolontiya enempilo (malunga 0.6-1.5%).

Emva contact 6alfa-methylprednisolone-17-propionate egazini systemic kugxalathelana kokuba conjugated kunye glucuronic acid kunokuba ngokukhawuleza, ize emva koko inactivated.

Metabolites kuthetha zicingeleka nya ingakumbi izintso emva kweeyure ezili-16. Izithako ezisebenzayo ze ichiza azikho cumulate enyameni. Ngenxa absorbability phantsi urea ngokusebenzisa ngokwemixholo ukucingeleka cream yeziphumo systemic okungenamsebenzi.

ubungqina

Ukususela ngoko bamisa "Komfoderm" (cream)? Imiyalelo yokusebenzisa iqulathe uluhlu zilandelayo zibonisa:

• onokhwekhwe amagciwane;
• dermatitis komzimba (contact);
• neurodermatitis, dermatitis atopic;
• onokhwekhwe oyinyaniso;
• dermatitis elula contact;
• disgidroticheskaya nerhashalala.

Ngamanye amazwi, ichiza kuthethwa eboniswe izifo ukudumba dermal, soprovozhdayuschihesya keratinization disorder, ngokunjalo abonise uvakalelo oluphezulu kunyango kunye glucocorticosteroids mlonyeni.

Izimo

"Komfoderm" imiyalelo Drug ukwenzela ukusetyenziswa nto leyo efunekayo zokufunda zonke izigulane, ukuba zisetyenziswe:

• Hypersensitivity ku iziqalelo cream;
• isifo sephepha okanye iinkqubo syphilitic kwi yokulahlwa kwe medicament;
• amagciwane (kubandakanywa varicella, i-herpes zoster);
• Rosacea, dermatitis perioral ekusebenziseni namafutha;
• naluphi na uhlobo zisigonyelwe;
• kweminyaka.

Medicament "Komfoderm" (amafutha): imiyalelo yokusetyenziswa

arhente Price ingxelo malunga 480-530 engange. Ichiza isicelo kwimimandla isikhumba achaphazelekayo umaleko obhityileyo, kanye ngosuku.

Ubude unyango rhoqo yonke imihla kunye nale cream mayingagqithi kwiiveki ezili-12. Kufuneka kuqatshelwe ukuba unyango kolusu kufuneka wenziwe iintsuku ezi-5.

imiphumela emibi

Basabela nendalo kunokubangela amayeza "Komfoderm M2"? Imiyalelo iingxelo zokusetyenziswa imiphumela enjalo zinqabile kakhulu. Baya ngesiqhelo kwi ngohlobo abasabela ilandelayo wengingqi: ukurhawuzelela, erythema, uvutha imvakalelo, ukubunjwa kwamaqhakuvana vesicular.

Xa kunjalo, ukuba medicament sisetyenziselwa elingaphezu kweeveki ezine, okanye kwiindawo ezinkulu kakhulu eluswini, isiguli wesikhumba yoma okanye telangiectasia mayibonakale akneformnye utshintsho, iimpawu ukuzolula kunye neziphumo zenkqubo, ezo zibangelwa kukufakwa corticosteroid.

kweziyobisi Kananjalo ngamanye amaxesha ingqalelo ebangela hypertrichosis, folliculitis, ibala ulusu, dermatitis perioral, kunye negazi.

ncomo Consumer kunye analogue "Komfoderma"

kuphela cream "Advantan" libhekisela analogs kweli chiza.

Yintoni abantu bathi ngayo "Komfoderm" iziguli yamafutha aqholiweyo? Ngokutsho iimpendulo zabo, lo medicament uchaphazelekayo indlela yasekuhlaleni kakuhle kakhulu. Isicelo wayo ikuvumela ukuba bahlukane izifo zolusu ezahlukahlukeneyo, kuquka nangokhwekhwe, neurodermatitis, kunye dermatitis. Kwezinye iimeko, ichiza usetyenziswa ukhwekhwe.

Ububi i "Komfoderm", linamafutha ziquka indleko yalo phezulu, kwakunye ekungakwazini ukusebenzisa ebantwaneni.