Metaplasia isisu esiswini: iimpawu, unyango. metaplasia carcinomas - a ...

Abantu abaninzi abafunyaniswa nezifo ezifana metaplasia esiswini amathumbu, abonakala esenza le epithelium esiswini apha emathunjini. Zehydrochloric acid iveliswa iiseli Parietal ayeke ukwenza umsebenzi wayo, ngaloo ndlela baqalise amalungu yokucola ukutya egxobhekile.

Imeko yomntu xa kuthe kwavela isifo eso kuthathwa ukuba yingozi, kodwa siyanyangeka. Ukuba endaweni kwiiseli esiswini yenzeka lokwanda iiseli colon, loo nto ithathwa imeko precancerous. Nangona unyango kulo mzekelo yaye kunokwenzeka, kodwa iintlobo eziphambili kukho ALS kakuhle kakhulu.

Yintoni metaplasia emathunjini?

Esi sisifo apho ancedisana isifo esiswini athathelwa indawo iiseli emathunjini. Ngokuba lixesha lokuqala sifo iye yachazwa kwiminyaka engaphezu kwe-100 eyadlulayo uProfesa Kupfer. Le ngezifo isikakhulu kuchaphazela abadala. Ngokutsho manani,-80% ezigulane babe gastritis ezingapheliyo kunye isilonda duodenal.

Kubantu abasempilweni, inyama nesigubungelo iindonga esiswini, bonke ihlaziywa. Ukuba umonakalo kwenzeka, iiseli aqale ukukhula ngamandla, nto leyo ngcono imfuduko labo kunye nokufunyanwa cell yokuvuselela. Le nkqubo izigulane gastritis ezondeleyo kuphazanyiswa, ngenxa apho ingaba esiswini sele wayeka ukuba enze imisebenzi yawo, ekhokelela ekumisweni metaplasia.

iintlobo zezifo

Metaplasia ye nesisu yeentlobo ezimbini:

• yesisu ezincinane (ngokupheleleyo, oqolileyo);
• Colonic (aziphelelanga, immature).

Le fom oqolileyo luphawulwa bubukho iiseli leyo kunokuba kuphela emathunjini amancinci: sulfamutsiny, ibizivalele, enterocytes engenamqheba. Noko ke, lo msebenzi osemqoka eliyintloko engqina olu hlobo leengxaki zithathwa iiseli Paneth. Isisu inyama kuqala bafana emathunjini amancinci njengoko isakhiwo kunye neempawu ezisebenzayo.

metaplasia olungekagqibeleli esiswini uphawuleka nokwanda kakuhle kunye nophuhliso kwamadlala esiswini kunye epithelium amaninzi limelwe iiseli colon.

Kufuneka wazi ukuba umhlaza esiswini ngo-94% amatyala ibhaqwe metaplasia ayiphelelanga. Loo meko kuthathwa precancerous, zila unyango liyabulala.

Ngaphezu koko, kubalulekile ukukhumbula metaplasia ingakumbi carcinomas. Makhe sihlolisise oko iinkcukacha ngakumbi.

Yintoni metaplasia carcinomas?

A phawu yale leengxaki kukuba endaweni epithelium oluqhelekileyo wakubo maleko carcinomas yenziwe. Enkabeni yalo, kube yinkqubo kufakwe kweeseli abaqolileyo kakhulu neenkalo ngaphantsi oqolileyo. Le yokugqibela kufuneka ukukwazi ngakumbi ukuba bhetyebhetye, njengoko ngokufuthi similise naziphi na iintlobo iseli ukuba babe ukumelana eliphezulu imiba eyahlukeneyo umonakalo.

Umzekelo, epithelial metaplasia carcinomas izilonda esiswini esiswini inceda azikhulule umonakalo enzyme kwemfuneko acid. Xa esahlala isusiwe, inyama ubuyela kwimeko yayo yesiqhelo.

Noko ke, njengokuba umqondiso inkqubo zophendlo lwezifo ezifana uhlobo metaplasia njalo izinto ezingqongqo. Oku kukhokelela ekubeni into yokuba iiseli ubuntwana, ezama ukulungisa, ukuqala ukuze yande inani elikhulu zofuzo kwaye akukho saba nako ukuzibamba iyantlukwano yabo, ajike abe ngumhlaza zeendawana.

Kutheni kwenzeke metaplasia?

Esi sifo luphuhlisa ngenxa yezi zizathu zilandelayo:

• ukudumba ingaphakathi isisu ebangelwe ezahlukeneyo imiba;
• ukukrala ezingapheliyo ka nyama umphimbo;
• zeleka rhoqo;
• izifo hormone;
• kwinwebu nesiqephu zesisu;
• gastritis, elibaleka ixesha elide.

Ingaba sifo ukubonisa njani?

Sisifo ngokwayo akukho ndlela kubonakala, yaye zonke iimpawu metaplasia enohlobo ezinxulumene izifo ukuba zibe negalelo kuphuhliso yayo. Ezi ziquka:

• isicaphucaphu;
• ukulahleka emnyama;
• intlungu zifutha kule ngingqi epigastric.

Ukwanda asidi esiswini ihamba reflux acid, "olambileyo" intlungu, bakwazi ukukhula ebusuku. Ukuba metaplasia isisu ababehamba aphoswe kuvuleke iminxunya kwiziqulatho esiswini, kubonakale ukuhlanza nobukrakra emlonyeni.

ekuxilongweni

Ukuchonga uhlobo sifo, wenziwe iimviwo histological. Kubalulekile ukuba umzimba womntu bavela ngamaqhekeza amancinci yezihlunu kwaye efundwayo. ucingo Indlela okanye iiseli epithelial ebizwa biopsy. Le ndlela uphethwe zicingeleka efunekayo xa kukho urhano of yobubi.

Ukuze ubone iqondo umonakalo iphecana zesisu, uphando ikhutshwa phandle esebenzisa izixhobo endoscopic. Lolwabo ezikrokrelekayo, zidyojwe a paint nezikhethekileyo ingozi ngokupheleleyo emzimbeni womntu. Xa yonakele iiseli, zinaso umbala okhethekileyo, yaye ngokucacileyo phantsi ngemicroscope.

Iimpawu zonyango

Ukuba unesifo metaplasia isisu, unyango lwesi sifo lwenziwa amayeza kunye nendlela ngokukhawuleza. Isigulane kufuneka ibhaliswe a gastroenterologist.

unyango amayeza

Le ndlela zonyango isetyenziswa kwezi meko zilandelayo:

• ukuphelisa izifo reflux gastroesophageal - isifo esibonakala isimemo ngendlela phezulu imixholo kuvuleke iminxunya asidi esiswini, njengoko konakalisa isifo;
• ukunqanda ngamathumba ebubonisayo;
• ukuba zokuyifihla secretion esiswini.

Kuba unyango ugqirha wakho unalo ilungelo lokumisela iziyobisi zilandelayo:

• Proton Pump inhibitors - amachiza mihla ephungula iasidi esiswini. "Omeprazole" sibaphatha, "Rabeprazole" "Pantoprazole".
• Asidi ( "Fosfalyugel", "Maalox") - iziyobisi ezikhuthaza neutralization of zehydrochloric acid.
• H2 - blocker histamine ( "Ranitidine", "cimetidine") - amachiza antisecretory.
• Gastroprotectives - ukuba ubumuncu eyandisiweyo esiswini, zinceda ukuthintela ekutshatyalalisweni isifo.

ukungenelela kuhlinzwa

Ukuba unyango elondoloza engazisi iziphumo ezidibanisayo, ngoko ugqirha angase akukhuthaze uqhaqho. Njani neengcambu metaplasia? Oku kwenziwa ngokusebenzisa izixhobo ezizodwa endoscopic ukunciphisa iqondo yokwenzakala, yaye oku kuthiwa uqhaqho kancinane wesibeleko esigqibeleleyo. Ukuba kuyimfuneko, indawo zonakaliswe isuswe ngokupheleleyo. Loo indlela amaxesha onyango amaninzi lunciphisa ubungozi kwingxelo umhlaza.

ukuvimbela

Ukuze kuphetshwe zezifo ezifana metaplasia isisu, kufuneka athobele imiqathango zokuthintela.

Kuyimfuneko ukuba siphephe ukubonakala ntshikilelo, ngokuqinisekileyo ukuphendula nayiphi na ezintweni. Qiniseka ukuba ukhululeke ngokupheleleyo.

Kulandelwe imigangatho yococeko zokutya. metaplasia esiswini isisu nje kuphela Helicobacter bacterium, kodwa nezinye izifo. Ukongeza, ukuba imimiselo yococeko aphulwe, amathuba okufumana ityhefu ukutya, oko kuya ukubacaphukisa ngakumbi isifo esiswini.

Kufuneka kwakhona unamathele ukutya okunempilo. Kule meko kuyimfuneko ukulishiya ngokupheleleyo substitutes imichiza enjalo, njengoko iziselo nezihlwahlwazayo, okuneziqholo, ethe shinyi, ukutya ezinetyuwa, inyama. Kungcono kakhulu ukubandakanya ekutyeni kwakho ekutyeni, osisityebi ifayibha zokutya. Kunokuba iindidi okuziinkozo, imifuno, imifuno, iziqhamo, isonka sengqolowa yonke.

isiphelo

Ngenxa yoko, siye safumanisa ukuba metaplasia ezinjalo. Esi sisifo eziyingozi ezinokuthi zibe negalelo ekusekweni umhlaza isisu. Kuphela isibheno ngexesha ingcali kunye nokulandelwa zonke iingcebiso eziyimfuneko ezinokucothisa okanye umva iinkqubo yingozi.