"Nalbuphine": umyalelo, inkcazelo, ukwakhiwa, izimvo

Kubuhlungu ... kubuhlungu ... Akukho namnye umntu ofuna ukuba ndiwathethe la mazwi. Xa into esinako, zonke ezinye iingxaki ziba ubala. Eyona nto ibalulekileyo kwaye okona kubalulekileyo kule ndawo - ukwenza ukungaphatheki wanyamalala.

Modern Pharmacy ukulungele ukunikeza nabathengi uluhlu enkulu lwamachiza iintlungu nemigaqo ezahlukeneyo amanyathelo. Enye imithi enjalo yi "nalbuphine." Okufundisela silawula njengento agonist kwaye receptor ochasene opioid, a iintlungu ezidakumbisayo, ziqukwe kuluhlu kuluhlu wesithathu iziyobisi ezidakumbisayo.

Ukwakheka pharmacodynamics

Lezithako "Nalbuphine" engundoqo esebenzayo i nalbuphine hydrochloride. Ichiza liqela iintlungu opioid (iziyobisi ukunika impembelelo kwi umzimba womntu, ezifana yesenzo umlaliso). Umgaqo ntshukumo ichiza "nalbuphine" umyalelo kwi isicelo ithi oku kulandelayo: eyona nto iphambili esebenzayo abangaphangeliyo ukosuleleka neemvakalelo intlungu phakathi luvo kwi luvo. Ichiza lukwakhuthaza iindawo eziphezulu lobuchopho, ngaloo ndlela ukutshintsha imbono ngokweemvakalelo intlungu.

Isiphumo "Nalbuphine" emzimbeni womntu ifaniswa kunye nefuthe "icaffeine". hydrochloride Nalbuphine eshukumisa iziko ukugabha, uyakwazi ukucinezela ikhaliphe moya, kuba okulalisa. Amayeza ofihla iziko yokuphefumla, kodwa luncinane kakhulu "icaffeine", "Promedol" okanye "Fentanyl".

ifomu Ukukhululwa balawule irejimeni

Abavelisi zinika abathengi babo iziyobisi ezineengqayi "nalbuphine 10" kunye "20 nalbuphine." ampoule nganye - 1 ml medicament. I ( "nalbuphine 10") zipakishwe ipasela ezineengqayi-10, yaye owesibini - 5. "Nalbuphine" (solution) imiyalelo ukusetyenziswa, iingcali zempilo lokwenene bacebisa onyule scheme ngqo ngamnye, ngokuxhomekeke ubunzima bomzimba, ubukhali intlungu ehamba izifo.

Le medicament linokwenziwa yegazi, intramuscularly okanye kwesikhumba. A idosi enye ukuba abantu abadala zingaqala 100 .mu.g 1 mg nganye ubunzima bomzimba kg. Ithamo yokuqupha umntwana - alikho ngaphezu kwe-300 g ngalinye 1 kg ubunzima bomzimba. Esi rhoqo isicelo medicament kuxhomekeke umfanekiso lwezonyango iyonke. Ikhosi unyango kufuneka kuhlala iintsuku ezingaphezu kwe-3-4, ekubeni ichiza a ezidakumbisayo, kunye nolawulo elide ukuze idle.

Iimpawu zibonisa ukuba ukusetyenziswa "Nalbuphine"

"Nalbuphine" yemiyalezo icebisa ukungenisa syndromes intlungu olomeleleyo esinxulunyaniswa ne xesha postoperative, ungenelelo yamanina zoqhaqho kwi unyango isifo sentliziyo kunye nesifo somhlaza.

Kwakhona, iyeza lisetyenziswa kwimeko (ukulungiselela pre-lwemithi umguli zomzimba jikelele kunye notyando) prednarkoznoy premedication. Eneneni, injongo ephambili yale nkqubo - ukunciphisa izinga nokukhathazeka kumguli ekomelezeni amanyathelo iziyobisi ukuze zomzimba. Enyanisweni, oku yengundoqo i indawo lwesicelo se hydrochloride nalbuphine.

Ngubani kufuneka ayeke ukuthatha?

"Nalbuphine" umyalelo, impendulo kunye iingcebiso zeengcali azivumelekanga ukuba ukwamkela izigulane hypersensitivity kakhulu ukuba eyona nto engundoqo esebenzayo. ukusetyenziswa medicament azamkeleki ukuba unyango izigulane abanengxaki kuzo zonke iintlobo zezifo kwesibindi kunye nezintso. Oku kubangelwa yinto yokuba umzimba "Nalbuphine" esibindini. Ifomu yokuqala medicament esiswini saso umchamo (70%) ngohlobo avela kwazona kwi enyongweni.

Akukho chiza elawulwa ukuba izigulane kunye notywala kunye ukuxhomekeka neziyobisi. Ngaphandle imfuno ekhawulezileyo iyeza akukhuthazwa ukuba zisetyenziswe ebantwaneni. Ekubeni "nalbuphine" unefuthe kumaziko aphezulu ingqondo, ayikhuthazwa ngexesha unyango izigulane ezingazinzanga ngokwasemoyeni (ukuba ukugula ngengqondo, ukudandatheka njalo njalo. N.).

ukusebenza Spillover "Nalbuphine"

"Nalbuphine", ukusetyenziswa apho kungenxa impembelelo ezidakumbisayo emzimbeni womntu, kunokubangela iziphumo ezingalindelekanga ethile ukususela kwiinkqubo ezahlukeneyo kunye namasebe. Ngenxa yoko, inkqubo sentliziyo unako ukuphendula ngokusetyenziswa tachycardia yophuhliso medicament, arrhythmias, ukuhla uxinzelelo lwegazi.

Ukususela luvo kunokubangela yintloko, uyinqaba okulalisa (silale), ibenza. Kukho izinto izangoma ezifana ukungahlaliseki, ukwanda ixhala. iphecana zesisu uzikhumbuze ngokubonakala ukuqunjelwa (ukungacoleki zonke iintlobo).

Kwezinye iimeko, nalbuphine amayeza ' "(manual iqulethe imiyalelo ezizodwa) ingadala ezahlukeneyo negazi (anaphylaxis kuquka).

Ke kaloku, njengokuba kuchaziwe ngaphambili, "nalbuphine" - ichiza ezidakumbisayo, ngoko kunokubangela ikhoboka.

ngeedosi kakhulu

Izikali medicament ngqongqo ngayinye ithamo ngasinye isigulane ekhethiweyo ngokuxhomekeke imeko jikelele, ubukhali iintlungu, ubunzima njalo njalo. N. Ndahluleleni isicelo ngaphandle igqirha kweliso kunokukhokelela overdosing. Kulo mzekelo, njengoko umthetho, kukho ezi mpawu zilandelayo: ukudakumba kwenkqubo luvo, silale, ongase (isichasi of 'imincili "mood odandathekileyo morbidly, nokubonakalisa ngokwayo xa nochuku, ubutshaba kwabanye, lula ndlongo, loqhambuko mood rhoqo). Libanda kungabangela ukungasebenzi kwiziko sokuphefumla.

Treatment sikuko ukusetyenziswa ebubuvuvu (kuba "Nalbuphine", njengokuba uninzi opioids - yi "Naloxone"), lavage esiswini kunye nonyango nomqondiso.

nabondli abalindele ...

Xa ukukhulelwa ukuqesha "nalbuphine" umyalelo ivumela kuphela ezibonisa engqongqo. Ngononophelo olukhulu amayeza emiselweyo ukuzalwa ngaphambi kwexesha kwiimeko apho kukho urhano of luhlaza Palsy. Ezi zenzo ezinxulumene yokuba "nalbuphine" ngokwaneleyo lula eyipasile umqobo placental kwaye kungadala ukudandatheka yokuphefumla kwi neonate.

Kwakhona kucetyiswa ngenyameko kakhulu amayeza ngexesha lokuncancisa, nangona 'Nalbuphine' yaye abelwe ubisi sikanina ngeedosi ezincinane, kuba akukho ukubaluleka lwezonyango (ngaphantsi kwe-1% yabo bebonke iziyobisi alawulwa). Noko ke, akukho mfuneko yokuba engozini umntwana ngaphandle kwesizathu esinzulu.

imiyalelo Special

A Isisombululo ukutofelwa kwayo mg ukubunjwa 10 / ml hydrochloride nalbuphine ( "nalbuphine Farmeks"), manual incomela ukuba isicelo ngenyameko kunene ukuphazamiseka umsebenzi yokuphefumla, ekubeni uyakwazi ukwehlisa isixa umthamo minute nokuphefumla kwi-25%. Phantsi kolawulo ugqirha kufuneka izigulane ezithatha 'nalbuphine "kwaye ngaxeshanye ukuya uremia ukubandezeleka kakhulu lwe ukungondleki, kwakunye nabantu abadala.

Kuba izigulane ngamayeza insufficiency kwezintso okanye hepatic ngononophelo kwaye ngqongqo ngabanye isilinganisi-manzi. Kufuneka kubenakho kumiwe ngokukhawuleza "Nalbuphine" kolu didi kwizigulane.

Nge siyiqaphele lichiza emiselweyo abantu kunye nomonzakalo lukakayi, njengoko kukho amathuba zokuphuhlisa inkqubo depression sokuphefumla. A ezinqwenelekayo kakhulu ukudibanisa ukusetyenziswa "Nalbuphine" kunye nezinye analgesics, ngenxa buthathaka analgesia kunokwenzeka.

Phantsi kweliso zonyango rhoqo kwaye ngeedosi ezincinane ichiza isetyenziswa imvelaphi narcosis, elele amayeza, anxiolytics, lakhula kunye neuroleptics. Oku "endaweni" kungabangela ukudandatheka kakhulu e-nervous system umbindi kunye neziko xi zokuphefumla yomsebenzi.

Amanyathelo "Nalbuphine" wabelwa ukuba ulwamkelo izigulane ambulatory, nelawulwa ngendlela, okanye abo ingqesho enxulumene izinga reactions lengqondo.

uhla amanani

Uluhlu Ixabiso ebanzi ngokwaneleyo ukuba "nalbuphine" iziyobisi. Imiyalelo yokusebenzisa, ixabiso echiza ubungqina bokuba ichiza kwemfuno phakathi kwabathengi. Ngaphezu koko, i iintlungu liseke ngokwalo njengoko ichiza ngempumelelo abasebenzi bonakekelo lwezempilo. iphakheji Product "nalbuphine 20" (5 ezineengqayi) kunokwenzeka ukuba bathenge ezikhemisti eRashiya imali kuluhlu ukusuka engange 620 ukuya 810. "Nalbuphine 10" iya kuxabisa ukusuka engange-650 ukuya-690 (pack of ezineengqayi 10).

Kwiikhemesti kunokubonwa athotyiweyo "Nalbuphine" kwi nesirinji (10 mg / 1 ml), zilungiselelwe inaliti enye. Indleko yale fomu woyekelelo ngeenxa 160 engange.

Intsebenziswano kunye namanye amachiza

Njengoko kuchaziwe ngaphambili, "Nalbuphine" (umsebenzisi iqulethe iinkcukacha) kunye lakhula, anxiolytics, neuroleptics, hypnotics, arhente iintlungu, iziyobisi antihistaminic kunye okulalisa, siphucula ukusebenza nokudakumba ethanol kwinkqubo luvo. Ukusebenzisa parallel iintlungu kunye penicillin kunye phenothiazine kunokubangela yokukhulisa isicaphucaphu nokugabha.

"Naloxone" (iyeza) kuya kunciphisa isiphumo sesichengeni opioids kwaye ngoko ukunciphisa ukudandatheka yokuphefumla kunye nenkqubo imisebenzi CNS kwabangela "Nalbuphine".

"Naltrexone" kukhawuleziswe kakhulu imbonakalo iimpawu yokurhoxiswa kwisiqalo yokuba likhoboka iziyobisi ( "kulo lonke uzuko lwayo 'iimpawu zinokuvela emva kwemizuzu emi-5 kuphela emva ulawulo ichiza, uya kuqhubeka ukuya kwiiyure ezingama-48). Symptomatology uqinile kakhulu, kuba zicwadi kunzima ukususa.

Uluvo kwabathengi kunye neengcali zezempilo

Izigulane ukuthetha "nalbuphine" njengoko iyeza ngokwanelisayo ngempumelelo kwixesha emva kokuba ungenelelo zotyando in Oncology. Nangona iziphumo ebezingalindelekanga nazo eziqhelekileyo yaye bakholisa ezivakaliswa yintloko, ukozela, ukungakhathali, ukuphazamiseka yokwetyisa. Ngokutsho iingcali zonyango, "nalbuphine" (Instruction, ukwakhiwa ke medicament, lo mgaqo nefuthe ezichazwe ngasentla) i iintlungu Kumlungele sisifo esibi ngokwaneleyo ezayamene neentlungu kakhulu.

Kukho olunye udidi abasebenzisi beziyobisi - Abaxhomekeki kwiziyobisi. Apha, iingxoxo kunye nohlaziyo bancipha umbuzo wokuba ingaba intshukumo iyafana "Nalbuphine" yaye "icaffeine". Ukusuka zonke, njengoko oko kungqinwa eli qela abathengi, kunokwenziwa isigqibo ukuba nomtsalane ngamakhoboka eziyobisi ukwenza "nalbuphine" ixabiso (ubalo manual kwizigulane ezinjalo ayamkelwa). Ichiza zibiza (amachiza nzima kakhulu), oko zingathengwa kuyo nayiphi na ekhemesti, Noko ke, ngokutsho iresiphi. Noko ke, ngamazwi abo, "isigqebelo phezulu, kodwa kokuqhekeka kwe-kakhulu wokwenene."

Ukusuka kungasentla kunokwenziwa isigqibo sokuba "nalbuphine," Kambe, a iintlungu kakuhle kakhulu. Noko ke, loo nto wathengisa kuphela kagqirha - kufanele. Ekubeni ugqirha idosi ngabanye ezikhethiweyo kwaye mode of application - isiqinisekiso sokuba isiphumo nesiyobisi emzimbeni wakhe uya kuba HIV, kunye nengozi neziphumo ebezingalindelekanga - ubuncinane.