Prednisolone: imiyalelo ukusetyenziswa, iipropati imithi

Release ifomu "Prednisolone" iziyobisi: iifomu ezithambileyo amayeza - linamafutha aqholiweyo.

Farmsvoystva

Prednisolone i analogu dehydrogenated of hydrocortisone. Antiallergic, antiinflammatory, isiphumo antiexudative kunye antipruritic xa kusetyenziswa ngokwemixholo, linamafutha aqholiweyo "prednisolone" umyalelo ebangela ukwehla ukusekwa, ukukhululwa kunye nomsebenzi yabalamli ukudumba (kinin, a histamine, enzayim lysosomal, prostaglandins). Kwakhona ezi Webhsayithi iseli yokufudukela ukuya kumbindi womhlaba yokukrala kunciphisa vasodilation kunye nokwanda semithambo permeability okwenzeka ukudumba. Ukunciphisa exudation kungenxa intshukumo vasoconstrictor of "Prednisolone" iziyobisi. Manual ibonisa ukuba ichiza isiphumo immunosuppressive ngokuthi ziyibuyisela umva le yintshukumo iantigens-unalo zintsonkothile kwaye baba phezu kweendonga imithambo yegazi kwaye unobangela vasculitis komzimba. Ichiza abangaphangeliyo sisenzo macrophage, cytokines, iiseli ekujoliswe ezibangela uphuhliso uxabane uhlobo reaction dermatitis esosulelayo. Ngaloo bayakuqonda T-lymphocyte kunye macrophage awukwazi ukufumana ufikelelo iiseli ekujoliswe kulo.

Pharmacokinetics

Xa isicelo yobulawu "Prednisolone" wendele yaye into esebenzayo ukho egazini. Xa igazi plasma prednisolone ingxenye into enxulumene albumin kunye transcortin. Biotransformation prednisolone kwenzeka igcwala, ikakhulu esibindini, apho glucuronidation okanye sulfation lwenzeka iintlobo oxidized. Xa uhlobo metabolites kwazona kwi umchamo kunye endleni, inxalenye - kwimeko unmodified. Prednisolone udlula njengomqobo placental kungomlinganiselo ezincinane, ingafunyanwa ngobisi lwebele yabafazi.

Prednisolone: ubungqina

Ichiza isetyenziswa kwiimeko:

- dermatitis contact komzimba kunye esahlala,

- nangokhwekhwe,

- atopic dermatitis,

- dermatitis seborrheic,

- ukhwekhwe.

Prednisolone: imfundo

Kwamafutha libhekisela kwisiza inxeba ngokulinganayo amaxesha 1-3 / ngosuku. Ubude unyango ibangwa yohlobo isifo kwaye ngokuqhelekileyo ithatha iintsuku 8-14. Amafutha kwi unyango yabantwana ubude unyango kufuneka incitshiswe kakhulu kwiintsuku 3-7, ekubeni umzimba umntwana olubuthathaka kakhulu kwi "Prednisolone" iziyobisi. Umyalelo icebisa bashiye Ukufudumala, ukulungiswa kunye zokubopha occlusive.

Iimpawu ze isicelo

Ubude unyango ngamafutha kufuneka ungabi ngaphezu kweentsuku ezingama-14 ukwenzela ukuba kuthintelwe iziphumo ebezingalindelekanga kunokwenzeka ukususela ukusetyenziswa "Prednisolone" iziyobisi. Umyalelo umisele ukunyanga kuphela phantsi kweliso zonyango.

imiphumela emibi

Kudla ichiza ukunyamezeleka kakuhle. Ayifane, ingakumbi emva kokuba ukusetyenziswa elide, kunokubangela ukurhawuzelela, uvutha imvakalelo, erythema. Kwezinye izigulane iziphumo ebezingalindelekanga ukuze ibonakale njengoba folliculitis, hypertrichosis, dermatitis perioral, kukwalisa amacandelo amayeza. Ezi mpawu zingentla musa kufuna unyango ngokukhawuleza isuswe kwi ukupheliswa isicelo beziyobisi. Kufuneka kukhunjulwe ukuba isicelo se isithambiso nolusu kunye nokusetyenziswa ixesha elide (ingakumbi ngokoyiswa kwiindawo ezinkulu yesikhumba) ochaphazelekayo kuvela iziphumo ebezingalindelekanga ezikumila lwenkqubo.

Unxibelelwano namanye amachiza

Prednisolone umntu ipropati ukukhuthaza ukusebenza anticoagulant of anticoagulants. Kwenyusa amathuba ukopha ngexesha uthatha salicylates. Kwenyusa amathuba ukuphazamiseka electrolyte yokucolwa nolawulo ehamba womchamo. Kukho ingozi ekhulayo yetyhefu xa usebenzisa glycosides inhliziyo. Ukwehla ukusebenza hypoglycemic antidiabetic sehlise umsebenzi antibacterial of rifampicin. Akukhuthazwa ukuba zisetyenziswe kubanjiswene ne asidi.

Izimo

Unyango "Prednisolone" umyalelo mafutha kungavumelekile:

- hypersensitivity;

- bacteria, egazini, kolusu ezinzwaneni;

- TB, negcushuwa, nangezilonda ulusu, ukukhulelwa, induna okuqhelekileyo induna pink.

libanda

Amatyala libanda ayaziwa.

iimeko yokugcina

Agcina kuluhlu B, ku 5-15ºS. Impilo - kwiminyaka emi-2. Ekupheleni ezikhabhathini ukuba ukuyisebenzisa.

nemiqathango yonikezelo

Ngawo.