Pseudomonas aeruginosa: unyango ingakumbi

Pseudomonas aeruginosa okanye Pseudomonas aeruginosa - ezinokususwa Igram ibhekisela olungenelelayo. Kwindalo, alaqhenqetha ngokubanzi, sihlala kumhlaba kunye namanzi, kwizityalo, kwisiqwenga zesisu kuzo zombini izilwanyana kunye nabantu. Mhlawumbi ehamba uninzi micro-ntsholongwane ziyakwazi ukuba ilandelwe iisampula zamanzi ezithatyathwe kwimithombo yendalo.

Yintoni eyahlukileyo kwezinye na iintsholongwane olungenelelayo, kutheni ingqalelo kangaka koogqirha kunye izazinzulu umdla Pseudomonas aeruginosa? Unyango kweenkqubo zophendlo lwezifo okubangelwe yile silwanyana, kunzima kakhulu, lo wand na multiresistant-antibiotics. Kunye Mycobacterium tuberculosis kunye iintlobo ezithile staphylococci, kokwabo gciwane kakhulu ukumelana ukuba chemotherapeutic iziyobisi ezikhoyo namhlanje. Kodwa kule kuluhlu, oko kudla kuthatha indawo phambili.

Oku kungenxa ebusweni biofilm, nto leyo eye indima yokhuselo, kwakunye njengesithintelo eyenziwe yi-lipopolysaccharide ndizayo engaphandle. Kwaye kukho iintlobo ezo abanganyangekiyo antibiotics phantse zonke ezaziwayo namhlanje.

Noko ke, Pseudomonas aeruginosa, amalungiselelo unyango leyo iba yingxaki, olunenkathalo phenol (2% isisombululo), 3% iperoksayidi yehidrojeni kunye chloramine (0.5% solution). Kwimeko-bume, ingakumbi amanzi kunye nomoya ulophu, igciwane unako kuphela iqhubeka ixesha elide, kodwa zixhaphakile. Ngeyona ndlela inenzuzo enkulu kuphuhliso yayo ithathwa 37 ° C ubushushu, kodwa kwi 42 ° C lesifo ekwaziyo yokukhula.

Pseudomonas aeruginosa: Iimpawu

A indima ebalulekileyo kakhulu kuphuhliso bacterium zosulelo nosocomial, kukho umngcipheko ngokwemiqathango zokugula olubi, izindlu zangasese, avuzayo nezibambo ezaphukileyo, izinto ezimanzi (iitawuli, umzekelo). izilonda Local akholisa ukubakho kwisiza amanxeba kunye beentanda postoperative, amanxeba nezinto amanxeba. Kudla ukufumana ntonga otitis, pyoderma, dermatitis. Ngenxa yokwenzakala okanye uqhaqho igciwane kunokubangela usulelo lwe iliso, kwakunye womchamo (kaninzi usebenzisa catheter).

Kuba iinkqubo ezinzulu ukudumba, yona unokubekwa ityala Pseudomonas aeruginosa, iquka endocarditis (ukonakala kwemithambo yenhliziyo), inyumoniya, ithumba ingqondo, meningitis, ukothuka syndrome, amalunga. Ngokubanzi, ukugula okubangelwe yile intonga, ngokufuthi kukhokelela bacteremia - usulelo umzimba uphela ngokunxulumene kwii yomenzeli ezosulelayo egazini.

Eyona uphawu le bacterium a endo- ngamandla ukhetho kunye exotoxins, hemolysin, cytotoxins, umsebenzi omkhulu proteolytic, intlaka yokuhlanganisa iminombo echumileyo hyaluronidase, ubuchule nokulungelelanisa elibona krahmalopodobnogo njengoko yencindi, nto leyo eyandisa iimpawu zayo yokuncamathelisa, kwakunye nenani zombala. Nezilonda ezibangwa uthe silwanyana kwenzeka ezineempawu kakhulu kunxilwe, iqondo eliphezulu. Ngokukodwa, Pseudomonas semiphunga umyalezo usoloko ihamba nzima, bukela iincopho kusasa fever, iphika cyanosis. Izinga lokufa eliphezulu (50-60%) yabonwa kwi meningitis kwaye, ukuba ukufunyanwa isigulane, izenzakalo gqolo ntsalela waphawula njenge zizigulo gross-luvo.

aeruginosa Pseudomonas: unyango

Okokuqala kufuneka iindlela elebhu ukuba ukujonga uvakalelo ka pathogen ukuya ichiza. Unyango Pseudomonas aeruginosa, njengoko umthetho, ufuna ukuqeshwa ezininzi (ababini ubuncinane) of antibiotics. Xa Okubuhlungu, ezisongela ubomi iimeko apho ixesha ukuba silinde iziphumo izityalo alikwazi ukugunyazisa nemithi, leyo adla iintsholongwane ezibuthathaka, ukuba idosi iphezulu. Ezi ziquka iziyobisi penicillin yesihlanu kwaye isizukulwana yesithandathu (amdinotsillin, pitratsillin, azlocillin). Amaxesha amaninzi kukho olusebenzayo carbenicillin. Applied kunye cephalosporins - tsefzulodin, ceftazidime. Kumaxesha amaninzi edityaniswe i aminoglycoside. Ngempumelelo kunye nokusetyenziswa efakwa ngayo ciprofloxacin. Emva kokufumana iziphumo imbewu ukucacisa kwisekethe therapy.

Xa engamabhodlo, ezondeleyo, ndangenwa lula zizifo self-ephilisa izifo, ezo zibangelwa yi-Pseudomonas aeruginosa, unyango akusoloko efunekayo. Kwiimeko ezininzi kwanele ukwabela olwa omnye. Kutsha nje, ngokuba unyango Pseudomonas bacteriophage lisetyenziswa ulwelo. Nangona kunjalo, kufuneka kukhunjulwe ukuba olu mzekelo kuyafuneka ukumisela uvakalelo ka pathogen kumalungiselelo zebhayoloji.