ACAT and Alat - iqhelekile abadala kunye nabantwana

Alat (igama elizeleyo - alanine) - enzyme eveliswa esibindini kwaye ithatha inxaxheba acid acid ukutya. Ukuba izinga Alat igazi eliqingqiweyo, oku kube ngumqondiso wokuqala yokugula. I-enzyme imali kakhulu zigcinwa esibindini, izihlunu skeletal, sezintso umsipha intliziyo. Kwaye ngaphantsi kakhulu ngawo serum igazi, kuba izinga igazi Alat zazimela isixa kakhulu iziyobisi. Egqithayo ingaba ngumqondiso wokuqala nawuphi ngezifo, kodwa akubi njalo.

Ukuba imizimba yeseli, equlethe izinto ngenxa yesizathu esithile ziqala ukuyeka, ngoko ke igazi kukuninzi eza Alat. KwiSithethe in serum igazi - malunga 0.1 ukuya 0.68 mmol / ml iiyure 30-40 okanye iiyunithi ilitha nganye .. Oko kukuthi, emzimbeni womntu qete ibe ncinci kakhulu langoku Alat. ISithethe abafazi oko iiyunithi ukuya ku-31 ilitha nganye, ngokuba abantu - kwiiyunithi 41 ilitha nganye. Luyanda Alat kunokubangela izifo ezifana hepatitis, ukwenzakala isibindi ityhefu, okanye umhlaza wesibindi, ukuqina kwesibindi, butywala, isifo sentliziyo - a iposi engabalulekanga okanye ukusilela intliziyo, ukufa izihlunu skeletal. Kwakhona, emva kokuba ukothuka esinzulu okanye ukutsha ukuze ukwandisa Alat. Ummiselo kudla ngaphaya xa ndamelwa yintliziyo omkhulu. Kwaye wongeza kakhulu ngexesha okuthatha losulelo hepatitis B.

ACAT (igama lakhe elipheleleyo - lutamat oxaloacetate transaminase okanye aspartate) - yoxinaniso enzyme mkhulu myocardium, isibindi, izintso kunye umsipha skeletal. Le enzyme iyasebenza kakhulu ngabantu ababhinqileyo. Ukuba ACAT umsebenzi negazi inyuswe, oko kusenokubonisa umonakalo emzimbeni iiseli, kungcono - ephula imisebenzi kwegunya. Ukuba kubekho umonakalo imisipha intliziyo; kulo mzekelo kukho nokulatyuza mkhulu umsebenzi ACAT - umsebenzi wayo kwandisa kangangezihlandlo ezingama-20. Le nakujoliso olutsha ngaphezulu kwe necrosis kwi myocardium, kokukhona umxholo enzyme egazini. Blood norm Alat abantwana abamnyama ababhalisiweyo angaphantsi kakhulu kwi-avareji kunokuba abadala. Xa igazi amantombazana abaneminyaka eyi-7 ukuya ku-12, umlinganiselo 13-21 ingqamana omnye, yaye abafana abaneminyaka efanayo, le umtya, i ezisezantsi neziphezulu izibophelelo linokuba ngaphezulu ngomyinge kweeyunithi 4. Xa abakwishumi elivisayo, izinga igazi Alat lingaba ngaphantsi koko abantwana abangaphantsi. Ngoko ke, abaneminyaka eyi-13 ukuya ku-17 ngo-amantombazana, kolundi izinga ukusuka iiyunithi ezili-10 ukuya kwi-13 ilitha nganye, emakhwenkweni eqela elifanayo ubudala - ukusuka 10 ukuya 15. Eli nani avareji kwabantwana Alat. norm yayo amadoda amakhulu ayitshintshi, kwaye abafazi abadala - Sehle iiyunithi 2-3 ilitha nganye.

Kwaye ALT, kunye AST zizinto enzymes - aminotransferase. Ezi enzyme esebenzayo kakhulu kuyo umzimba nawuphi na umntu. Uninzi ALT esibindini, kwaye ACAT - kwi nezihlunu izihlunu - ingakumbi izihlunu engabalulekanga kwemisipha kwentliziyo. ACAT nto ndiyibhalayo cytoplasmic kunye ayo isozyme isozyme. 80% of umsebenzi ACAT iwela isoenzyme cytoplasmic. Egazini serum ezi isozymes ezimbini lidla echazwe cytoplasmic kuphela.

AST Eqhelekileyo, ALT obukhulu amanxeba ezahlukeneyo esibindini. Ngokukodwa, izilonda utshwala, zamachiza okanye ityhefu, ukuqina kwesibindi, hepatitis, njalo njalo. Ukuba ezinetyhefu isibindi yityhefu ngenxa yokufakwa amayeza athile, ngoko norm ACAT Alat ngaphaya apho. Naziphi na iziphumo yityhefu ophezu kwesibindi kunokukhokelela yoko onjalo. UNorma AST, ALT, ndanda ngenxa yeemeko ukuba nanto yakwenza iingxaki esibindini. Ezi zinto zibandakanya ubudala usana - ukuya kwiinyanga ezintandathu (ukunyuka kwezinga ezi enzyme abantwana eqhelekileyo), umonakalo izicwili intliziyo kwezihlunu, stroke ubushushu, ikhondo FOBS ukugula ebantwaneni, nangokurhala kwezihlunu, kubazali bakhe, nokutyeba kunye nabanye abaninzi.

UNorma AST, ALT, kwaye bengaxatyiswanga kakhulu emzimbeni. Oku kwenzeka ngenxa ukusilela kwezintso, pyridoxine izivuka, ie, vitamin B. Kwakhona Kusenokwenzeka kakuhle ngenxa ihaemodialysis ngokuphindaphindiweyo. Kusenokuba ngokupheleleyo eqhelekileyo ukuba understated ukhulelwe ACAT (wamvusa) okanye Alat. kwiingxowa zaso ngexesha lokukhulelwa idla yoniwa ngenxa yokuba inkqubo ngokutsha ndawo baphathelane umama okhulelwe.