Ama-radicals amahhala-ngaba kufuneka siwususe umzimba?

Ekubeni kwicandelo lonyango lonyango enye yezihloko ezibalulekileyo kukuphanda ukwandisa ubomi nokuphucula impilo, umbuzo wokufunda isiphumo se-radicals yamahhala emzimbeni womntu uphakanyiswa. Ngelishwa, bonke abasebenza kule ndawo baxhomekeke kwimpembelelo yoshishino, ngoko ke abantu abangenayo imichiza yemfundo bafumana ulwazi olungachanekanga okanye olungaphelelanga. Abambalwa kakhulu abantu bayazi ukuba zonke ii-radicals zamahhala ziyingozi kumzimba womntu. Ininzi ithenga kwaye isebenzise iziyobisi eziphelisa ama-radicals, ngaphandle kokucinga malunga nokuba kuyimfuneko . Ekubeni kwihlabathi lanamhlanje imithetho yezorhwebo yindawo yokuqala, i-antioxidants ezipapashwe ngeendlela ezahlukeneyo zibiza kakhulu. Kodwa i-radicals eyona nto yamahhala emzimbeni womntu ayifuni kuphela ukuba isuswe, kodwa ngokuchaseneyo, kuyimfuneko ukukhuthaza imveliso yabo. Baya kuthatha inxaxheba kwiinkqubo zokuxilongwa kwaye bancede balwe nezifo ezahlukahlukeneyo. Kodwa ii-radicals zesekondari ziyingozi yaye zenza izifo ezahlukahlukeneyo.

Ngaphambi kokuba uthathe i-antioxidants okanye i-vitamin complexes, kufuneka uqonde ukuba bafuna ngokwenani, kwaye kufuneka ukuba basebenzise njani. Ama-radicals aseprayimari yama-free are radicals ne-nitric oxide kunye ne-lipids. Eyokuqala kwezi zivela ngenxa yomsebenzi weepagocyte kunye ne-macrophages kwiiseli. Ekubeni ama-radicals amahhala ayenama-molecule angenayo i-electron edibeneyo ngaphandle kwe-orbit, asebenza ngokukhawuleza. Ngombulelo kwindlela yokuzivikela yezofuzo, iiseli zilahla iamolekyu ezinjalo ngeempendulo zamakhemikhali. Emva kwezi mpendulo, i-hydrogen peroxide yenziwa. Isetyenziswa ngama-phagocyte kunye ne-macrophages yomsebenzi wayo, iyonakalisa igobolondo yangaphandle yeebhaktheriya kunye ne-microbes. Kodwa i-peroxide ye-hydrogen phambi kwentsimbi ijika ibe yinto ephezulu ye-hydroxyl. Inokhemikhali esebenzayo kwaye inokutshabalalisa phantse nayiphi na i-molecule yomzimba womntu.

Ii-radicals zamahhala ze-nitric oxide zikhutshwa ngexesha lomsebenzi we-macrophage, kwakunye neeseli zamanzi zesebe. Inani labo ngokuqhelekileyo le-metabolism lugqityiweyo ngokuqhelekileyo, ukuphambuka kubangela ukuba uxinzelelo lwexinzelelo okanye u-hypotension. Ekubeni kwe-hydroxyl, ziba ziyimichiza kwaye ziqala ukutshabalalisa iiseli. Ukuba i-oxygen radicals yamahhala ingeniswa kwiiseli ze-lipid, inkqubo eyintsebenzo enkulu yokutshabalalisa iqala. Ukuqaliswa kwempembelelo yekhenkethi kwenzeka. I-hydroxyls zisebenzisana nama-acids acids, eziyinxalenye yeembrane zeseli, ezibangele ukubunjwa kwe-lipid radicals. Baya kungena kwiimpendulo zamakhemikhali, emva koko i-lipid peroxidation yenzeka. I-radicals yamahhala ekhutshweyo yonakalisa iimbumba kwiiseli kunye neeprotheni.

Ukutshatyalaliswa okuqhelekileyo kumzimba womntu, ngenxa yokuba iiseli zihlaziywa rhoqo. Kodwa i-radicals yamahhala intshabalalisa nayiphi na i-molecule, kuquka ezo zine-DNA-code. Bayazi nendlela yokubuyiselwa, kodwa ngeendlela ezinjalo "zokuqala", "iiphene zamakhemikhali" zivela. Ngenxa yoko, iiseli ezintsha zenziwe ngokungalunganga, kwaye ekugqibeleni ziyeke ukwenza.

Njengoko sele sele khankanywe ngasentla, ukulwa nama-radicals, kukho iziyobisi ezinama-antioxidants. Ezi zinto zinika i-elektronti kwaye ayilonakalisi umzimba. Babonakala bexhuma ama-radical ezamahala, bengavumeli ukutshatyalaliswa ngaphezu kwesiqhelo. Ngokunyanisekileyo, umzimba womntu unako ukuvelisa i-antioxidants. Kodwa ukubonakala kwe-radicals ekhululekile kuchaphazelekayo kwizinto ezininzi, kwaye ukubonakala kwazo emzimbeni kudlulele kwisiqhelo. Nangona kunjalo, akuzona zonke i-antioxidants, ngokukodwa ezidalwe ngokufanelekileyo, zinenzuzo. Ukugqithisa kwenani labo liqala ukubopha kunye neerimali eziphambili zamahhala. Ukuba akukho nto ibonisa ukunyuswa kokwanda kwee-antioxidants, ngoko kugxininiswa kufuneka kube kukutya okunomsocoko, imenyu echazwe bhetele nogqirha ngumntu wesondlo.