"Diferelin": ncomo, analogs, kunye nemiyalelo yokusebenzisa

Enye amayeza kakhulu eyenzelwe ukuba kuliwe ngezifo kakhulu kwinkqubo nabakhonzazana, nabakhonzi nezenzala, sisiyobisi "Diferelin". Imiyalelo, ixabiso eli chiza idla kuxoxwa zizigulane kumaqonga ezizodwa. Njengesiqhelo, yaye eli chiza abaxhasi zayo neentshaba. Kweli nqaku siza kuxubusha indlela amanyathelo kweli chiza kunye neempawu zayo imithi.

elapha

Ukulungiselela "Diferelin" sisiyobisi kunye antigonadotropnym senzo. Enyanisweni, kuya kuba yinto anti-iihomoni, njengoko uyakwazi ukucinezela imveliso luteinizing hormone kunye hormone follicle-zivuse kwi kowesi- testosterone emadodeni. Ngoko ke, ukusetyenziswa esebenzayo "Diferelin" kweziyobisi ngenxa yonyango fibroids zesibeleko, endometriosis, umhlaza yesinye, ukufikisa kwangoko abafikisayo kunye nezinye izifo.

Isakhiwo kunye Nokuhlanganiselwa

Ukulungiselela "Difelerin" ifumaneka okwangoku kuphela ifomu idosi enye - lyophilisate ukwenza izisombululo. Kwangaxeshanye, yenza iintlobo ezintathu izixhobo, zoqhaphelo ezahlukeneyo into esebenzayo nokuba injongo ezahlukeneyo:

• "Diferelin" 11.25 mg kunye 3,75 mg - emigodini intramuscular;
• "Diferelin" 0.1 mg - kuba inaliti ongama.

Xa ukusetyenziswa, oogqirha nezigulane kungekudala obizwa ngokuba iintlobo vulavuriweke ichiza, ukongeza nemifanekiso yalo kwisihloko ukuchaza umxholo ukwimo engundoqo.

Njengoko njengempembelelo esebenzayo amayeza "Diferelin" ratings leyo yenza ubukhulu becala HIV triptorelin pamoate. Ukuba enalo isigulana abuthethileyo neziphumo zonyango kunye imithi.

Medicament "Diferelin" kuthengiswa iibhokisi, apho kukho iibhotile lyophilisate kunye isirinji kunye iinaliti ezimbini. Ukongeza, babeka nengqayi wesinyibilikisi. Inokubanomahluko. Ukuba lyophilizers "Diferelin" 3,75 no 11.25 mannitol isetyenziswa kukhethwa, lo medicament xa iqela 0.1 mg isetyenziswa kakhulu saline.

ukusebenza therapeutic "Diferelin"

Ukusuka Ngokwembono zengqo- hormone esebenzayo isiyobisi analog of yobuchopho GnRH kuhlelwe. Ichaphazela ingqondo yebhinqa inoxanduva kwimveliso hormone ngesondo, ngaloo ndlela elawula umsebenzi nabakhonzazana, nabakhonzi uhlelo zokuzala: esinobubovu yesinye, maqanda, wesibeleko, amasende. Kubonakala ukuba ilawula imveliso sex hormone amayeza "Diferelin".

Izimvo isicelo wayo ibonisa ukuba inaso isicwangciso esiqinileyo anti-thumba kunye antigonadotropnym nyathelo sisebenzayo ukuphathwa ezimbi ezithile. Umzekelo, nenzalo, eli yeza ofihla imveliso ye luteinizing ihomoni, leyo kabi ovulation, ngaleyo ndlela kwande amathuba okuba ukhulelwe. A medicament somdlavuza wendlala, oku kunciphisa amanqanaba testosterone ukuya zero, nto leyo uphawu ngenxa castrates, kwaye kwenyusa amathuba yomguli ngayo ndahlukane ngumhlaza.

magic olusebenzayo "Diferelin" kunye endometriosis. ifuthe lazo ekuvelisweni hormone ngesondo ngokuthe ngcembe ongena umfazi kwimeko ngumntu kokuya yaye ngaloo ndlela kudale yoma endometriodnyh nakujoliso olutsha.

Ubungqina obubonakalayo buxela

Kuxhomekeka boxinzelelo zineziphumo ezahlukileyo ichiza eziphilayo "Diferelin". Ukusetyenziswa kweli chiza kwi iyeza luxhomekeke umxholo kwi eyona nto engundoqo esebenzayo. Umzekelo, inaliti "0.1 mg Diferelin" kuboniswe nenzalo, ukuba ukuvuselelwa uvuselelo ovarian kunye ovulation in IVF.

Ukusetyenziswa kweli chiza xa iqela 3,75 mg kucetyiswa xa kusingethwe somdlavuza wendlala, fibroid isibeleko, zivuthwe phambi kwexesha, angasese kunye endometriosis extragenital, iiprotokoli IVF.

Kwiimeko ezininzi kakhulu somdlavuza wendlala kunye metastases kunye endometriosis ezingapheliyo, amisiweyo lolwamkelo esikolweni "Diferelin 11.25 mg." ukusetyenziswa kwayo unako ukuphucula ngokubonakalayo amathuba yesigulana alulame.

Imiyalelo yokusebenzisa

Medicine "Diferelin 0.1 mg" lisetyenziswa kwi elandelwayo ezimfutshane nezinde IVF phantsi kweliso zonyango olungqongqo. Oku kulawula mihla omnye ampoule ukususela ngomhla wesibini sexesheni. Ngethuba lokuqhuba kwale unyango kumiselwa iimpawu ngamnye umzimba ababhinqileyo.

Kodwa ichiza "Diferelin 11.25 mg" elawulwa kwizigulana qho kwiinyanga ezintathu. Yaye amadoda zingenza inaliti nangaliphi na ixesha, yaye abafazi - kuphela kwiintsuku zokuqala ezintlanu sexesheni. Ubude unyango kunye eli chiza ithatha ukusuka kwiinyanga ezintathu ukuya kwezintandathu, njengoko ngaphezulu kweenyanga ezintandathu, ayikhuthazwa tu.

Kuluhlu olubanzi lwezicelo amayeza "Diferelin 3,75". Baqinisekiswa ukukhombisa ukusebenza kweli chiza. Ngapha koko, kulula kakhulu ukuba ukusebenzisa, ekubeni ingakufuni ulawulo ngemihla ixesha elide. Iinaliti "Diferelin 3,75 mg" beziyobisi zidla kwenziwa kube kanye ngenyanga. Oku kwanele ukuqinisekisa ukunikezelwa kwezinto esebenzayo kwi egazini kwi iidosi zonyango. Makhe siqwalasele ukusetyenziswa kwalo medicament wesiphaluka zizifo ezahlukahlukeneyo.

somdlavuza wendlala

Abantu abavumelekanga eboniswe umhlaza prostate unyango "Diferelin". Isitofu isigulana zibekwe zonke iintsuku ezingamashumi amabini anesibhozo, kangangokuba lokuphumla phakathi ulawulo ichiza iiveki ezine. A idosi enye ye-sicelo medicament - omnye igutyana 3,75 mg. Ubude Ulawulo ichiza emiselwe izinga ukuphilisa isigulane.

endometriosis

Isitofu ichiza "Diferelin" amabhinqa endometriosis zifumaneka kwiintsuku zokuqala ezintlanu ezayo exesheni. A ithamo kweziveliso ze-amayeza eveliswe kweeveki ezine, yaye le khosi unyango ithatha abangama seenyanga ezi-3 ukuya ku-6. Kufuneka kukhunjulwe ukuba eli chiza ayikwazi zidityaniswe kunye nokusetyenziswa zokucwangcisa ngomlomo.

Xa unyango lwe endometriosis kubangela exesheni eyenziweyo (amenorrhea) ukulungiselela "Diferelin". Izimvo izigulane, nakuba kunjalo, lubonisa ukuba emva ekuyekeni unyango sexesheni ibuyiselwe kwiinyanga ezimbalwa, maxa wambi ngonyaka. unyango okuphindiweyo nale amayeza kunye endometriosis nezolo, njengokuba umthetho, akukho wabelwa - ngenxa yale njongo, amanye amayeza, ngaphantsi olusebenzayo.

Adrenarche

Abantwana yokubamba ukufikisa mveku iziyobisi "Diferelin" ezilawulwa kanye yonke imihla 28. Ngaloo nedosi enye ye-sicelo kubalwa ukusuka ubunzima umguli. Abantwana ubunzima phezu ngeekhilogram 20 laqalisa igutyana (3.75 mg), kunye nabantwana kunye indices ezincinane - isiqingatha ampoule (1.875 mg). Ubude uthomalaliso emiselwe igqirha khona ngokuxhomekeke isantya kuqheleke imeko yesigulane.

fibroids wesizalo

Xa unyango lwesi sifo ilawulwa kanye ngenyanga ibhotile amayeza single "Diferelin". Reception wayo kufuneka wenziwe ngethuba kwiintsuku zokuqala ezintlanu sexesheni yesigulana. izitofu elandelayo beziyobisi zenzeka rhoqo kwiiveki ezine. Ubude unyango ongowona ngaphantsi kweenyanga ezintathu.

libanda

Okwangoku akukho kutyhilwa na kwimeko amayeza "Diferelin" libanda. Baqinisekiswa zibonisa ngokhuseleko olubonakalayo yayo. Ukongeza, ichiza alunasiphumo kwi xi kunye nokukwazi ukulawula iindlela zokuthutha. Ngoko ke, ebudeni unyango nalo eli chiza kukhuselekile ukuqhuba.

imiphumela emibi

Xa usebenzisa i "Diferelin" ichiza sinokufumana nemiphumela emibi kulandelayo:

• iimpawu spinal intambo ucinezelo;
• ukwanda buhlungu;
• Angioedema, urticaria, ukurhawuzelela;
• ureteral kokuphazamiseka;
• intloko ebuhlungu;
• demineralization bone;
• yehle amandla;
• nokoma zangasese;
• ndiyabila;
• Ukwehla amasende;
• utshintsho ngobukhulu lwebele;
• amenorrhea hypogonadotropic;
• hypertrophy le amaqanda;
• menorrhagia;
• asthenia;
• isicaphucaphu, ukugabha;
• wegazi;
• komzimba;
• ukungaboni ;
• lability ngokweemvakalelo;
• hematuria;
• ukuvela ubunzima ukuzibhubhisa;
• nokudumba neuropathy;
• umkhuhlane;
• anorexia;
• ukudana;
• tachycardia;
• alopecia;
• dyspnea;
• ububomvu kuyo inaliti;
• paresthesia.

Izimo

Xa ichiza "Diferelin" Kukho ezinye Izimo ukusetyenziswa. Bona ezinxulumene imeko yesigulane impilo, kwakunye neempawu zawo ngabanye nokomzimba. Umzekelo, abantu abakwazi ukuthatha eli amayeza kunye hormone-ezizimeleyo umhlaza wesinye emva ukushenxiswa amasende, nabafazi akunconywa ngexesha lokukhulelwa, lokuncancisa, kwaye polycystic isizalo syndrome. Wonke, ngaphandle kokukhetha, kufuneka usebenzise iziyobisi ngononophelo "Diferelin" kwamathambo kunye hypersensitivity amacandelo yayo. Ukuba naziphi na iimpawu ezibi, isigulane kufuneka ngoko nangoko udibane nogqirha.

nemeko ngokubanzi emva kokuba isicelo

Njengoko kukhankanyiwe ngasentla, ichiza "Diferelin" abangaphangeliyo ukuveliswa hormone ngesondo xa amadoda nabafazi, ngaleyo ndlela babe kwimeko xa kuthenwa ngumntu. Ngokucacileyo, ukutshona ukwimeko enjalo kwaye imveliso yayo ihamba ezahlukeneyo ngokwasengqondweni, ezidalwe-pathways kunye neuro-kwezityalo iingxaki.

Emva kokugqiba unyango ngale amayeza iihomoni zibuyiselwe, kodwa ngethuba le nkqubo lisenokubhidekisa kumguli nochuku, ukudinwa, intloko ebuhlungu, ukubila, komzimba, ukudakumba, umkhuhlane kunye nezinye iimpawu ezingemnandi. Noko ke, iinyanga enye enesiqingatha emva kokuphela ichiza eqhelekileyo ngokupheleleyo imeko yendawo yesigulana. Oko kukuthi, ngokubanzi emva naliti yokugqibela "Diferelin 11.25 mg" imali eseleyo kwi hormone ubuyiselwa emva kweenyanga 4.5, kwaye intshukumo ye amachiza xi 3,75 kugudiswa mg emva kweenyanga 2.5. Ngexesha la maxesha ixesha abasetyhini kunye namadoda ilungiswa ngokupheleleyo umsebenzi ekuzaleni yaye ngokwesondo kunye yobuntu ubuyela esiqhelweni.

ukukhulelwa

Xa unyango ngokuzala "Diferelin" contraindicated. Noko ke, le iyeza lisetyenziswa ukwandisa ovulation. abafazi abaninzi bayakwazi ukuba ukukhulelwa emva kwizitofu ezininzi ichiza, kodwa engazi, baye baqhubeka ukuthatha iyeza "Diferelin". Isiphumo eli chiza onako ukunizimasa, ngaba ukuwonakalisa umntwana ongekazalwa: hayi nimqumbise umngcipheko kwesisu kwaye yenza kube nzima ukuqhuba kuphuhliso malformations bekhubazekile. Nangona kunjalo, indlela amanyathelo ngayo iziyobisi female uhlelo zokuzala ngexesha lokukhulelwa nangoku kufuna ukufunda ngenyameko.

Drug analogue "Diferelin"

Emarikeni zoxubo yangoku kukho enye drug-kuyahambisana kuphela, ukuba kumafa wayo eyona nto efanayo esebenzayo - yi "Dekapeptil". Ukongeza, Pharmacy zinokufumaneka iziyobisi zinegalelo enyangayo efanayo njengoko ichiza "Diferelin". A nomphumela ofanayo umzimba inikwa: ukutshiza "Buserelin" lyophilisate "Buserelin Depot", "Zoladex" philisi nemixube "Eligardt" yaye "Lyukrin Depot".

reviews

Kukho zombini ingxelo ebezintle nezo zingentle ekusetyenzisweni kwamayeza "Diferelin". Isitofu eli chiza zineziphumo ezahlukileyo izigulane. abafazi abaninzi babone isiphumo enyangayo waniphawula ephilisa fibroids kunye nezinye izifo, kodwa, ezikhala side effects ziye ukunyamezeleka kakubi ngabo ikhosi yonyango: ukutyeba, komzimba, ukuba nochuku, ukudinwa. Ngelo xesha, zonke izigulane bayavuma ukuba unyango lovavanyo lichiza elinzima kakhulu nangoku uqhaqho kwisisu ngcono.

Xa unyango somhlaza wesinye nezinye izinto ezimbi ebantwini nabo zenzeka izigxeko bedidekile kwimiphumo iziyobisi "Diferelin". Ixabiso abaninzi isiyobisi babonakala indlela eyamkelekileyo isicelo kwakhona ubunganelisi, yaye ukuba luyasebenza kwaye yabhalwa bacule wendumiso, kuba ususa kuphela ithumba ngokwayo, kodwa ishenxisa metastases emathanjeni. Nangona kunjalo, kukho ncomo malunga namayeza "Diferelin" izizathu eziphambili ngenxa amabini athabathayo: amachiza ukuqhuba kakubi kwiimeko ezithile ezingqalileyo, yaye side effects ezithi ukunyamezeleka kakubi ngabanye izigulane kwaye kubangele ukuba ukuyeka unyango okanye kuwa ngokupheleleyo bayaphuma kwisingqi eziqhelekileyo ebomini.

amaxabiso

Yintoni na iindleko isiyobisi "Diferelin"? Ixabiso eli yeza kuyahlukana nedlela uhlobo, loo ikhonkco ekhemesti, wathengisa ngawo, yaye umda phezu kwempahla. Ngoko ke, ixabiso lentengiso ezineengqayi ezisixhenxe "Diferelin 0.1 mg" isusela ukusuka 2597-3107 engange. Uninzi oyidlayo uya kufuna utyalo-mali kakhulu: 1 ibhotile "Diferelin 3,75 mg," umthengi kuya kufuneka ukuba uhlawule ukususela 7632 ukuya 9076 engange. Ngokwendalo, siyobisi ibiza i enamanani amakhulu. Enye ampoule "Diferelin 11.25 mg" zingathengwa-18 269-23 100 engange.

Kunokuba ephezulu ixabiso ichiza "Diferelin". izixhobo ezifana kubiza, kodwa ukuqeshwa kwabo unokuthenjwa kuphela ugqirha onamava, ngenxa yokuba iimpawu ezahlukeneyo kakhulu amayeza, Izimo kunye neziphumo ebezingalindelekanga.

isiphelo

Ngoku uyazi konke malunga "Diferelin" iimpawu ichiza. Eli chiza hormone olusebenzayo izifo ezininzi, kodwa kunokubangela ezininzi yeziphumo ebezingalindelekanga. Phambi kokuqala unyango, isigulane ngasinye kufuneka balungiselele ngenxa yokuba unyango olunjalo kunokuba lucelo-mngeni nzima kuye. Nakuba kunjalo, nawuphi na umngcipheko sifanelekile na, ukuba busemngciphekweni Olusindiso kwaye ngamanye amaxesha umphefumlo womntu. Ngoko musa ukunikezela ukusetyenziswa ichiza "Diferelin" okanye uyitshintshe ufake analogue zitshiphu. Kubhetele ukuba uqale unyango kunye ndlela inempumelelo yaye ngaloo ndlela liqinisekise ukuba yabaneziphumo ezihle. Hlala uphilile!