Guide niacin

Niacin, imiyalelo zokusetyenziswa eza kuxutyushwa kweli nqaku, imele vitamin leyo inxaxheba kwiinkqubo oxidative kwenzeka ezikwiiseli eziphilayo sisiyobisi. Ichiza linikwa kwi ngokohlobo lomgubo incasa emhlophe imuncu kunye esha. Kunzima ukuba ukunyibilika emanzini abandayo.

Kufuneka ke ukuba nicotinic acid (okanye vitamin PP) is a vitamin, antiallergic, ezigulela kunye nearhente gipolipedimicheskim leyo eyenza igalelo ekuphuculeni ukutya ekudleni, vasodilatation, kuquka ingqondo, kokufuduswa oksijini esikule. Ibandakanya kwiinkqubo ezityebileyo ukutya, acid, iiprotheni kunye purines, ngokunjalo kwinkqubo biosynthesis.

Niacin, enika imiyalelo yokusebenzisa vitamin ukuya kumashumi amabini anesihlanu milligrams imihla ngemihla, xa ngeedosi eziphezulu (ukuya grams ezine ngosuku) ukucutha ubuninzi lipoproteins, triglycerides kunye cholesterol egazini.

Le ichiza ngokukhawuleza etsalwe iphecana emathunjini, kwaye uye uguqulwe imizuzu engamashumi amane nicotinamide. Vitamin umzimba esibindini, iya kuhlanganiswa ethunjini, apho ukubonisa memory nje metabolite.

Iimpawu zibonisa ukuba ukusetyenziswa kweziyobisi zezi: avitaminosis, ukutya parenteral, malabsortsiya, usinga ukwehla kobunzima, ukuphazamiseka acid nokwenziwa acid, isifo iphecana zesisu, imfuneko umzimba ukwanda ngenxa PP vitamin, ifiva, hepatitis, izifo ezosulelayo, leyo ezondeleyo ngokwendalo, kwakunye yamathumba yingozi, ukukhulelwa, zisanyisa, uxinezeleko. Kwakhona, nicotinic acid, imiyalelo zokusetyenziswa encamathele ichiza ezimiselweyo kwegazi ebuchotsheni, izifo amalungu omzimba, kuquka inkantsi zabo, izifo yenkqubo enzala, polyneuropathy kunye microangiopathy.

Nicotinic acid unalo Izimo zilandelayo: hypersensitivity ukuba ichiza, isilonda esiswini, gastritis, sifo, glaucoma, hypotension, abantwana abangaphantsi kweminyaka emibini. Kwakhona sebenzisa kakuhle eli chiza ukuze izifo yobuso luvo, ukudumba, enterocolitis, trophic kunye nonhealing amanxeba ixesha elide ixesha.

Nicotinic acid na iziphumo ebezingalindelekanga kulandelayo: ukuthoba eluswini, anozizi eluswini, inwebu yangaphakathi olulophu amehlo ulusu, kwakunye arrhythmia, isiyezi, isicaphucaphu nokugabha, pruritus, myalgia, hyperglycaemia, paresthesia. Onke la inokubonakalisa xa uthatha amathamo ezinkulu ichiza. Ukuba vitamin PP kusetyenziswa ixesha elide, kusenokubakho isibindi muscular, ukugungxula yobuso, asthenia, isiyezi, intloko ebuhlungu, ukwanda AST, ALP kunye LDH egazini.

Sebenzisa i ichiza emva esidlweni iidosi zilandelayo: abadala - milligrams ezingamashumi amabini anesihlanu ngosuku, abantwana abadala ngaphezu kweminyaka emibini - up to milligrams amabini ngosuku.

Kufuneka kukhunjulwe ukuba nicotinic acid isetyenziswa ngobunono zidityaniswe kunye anticoagulants kunye neziyobisi umfutho. Xa kunjalo, xa isetyenziswe kunye namanye amachiza kufuneka ukuba bajonge yincutshe.

Ngaphezu koko, ngokusebenzisa nicotinic acid kufuneka ukulungelelana ukutya (iimveliso eziqulathe methionine) kunye nolawulo rhoqo umsebenzi zesibindi. Ukuze kukufakwa ngcono kwisiqwenga zesisu Kucetyiswa ukuba basele ukulungiselela ubisi.

Ngenxa yoko, nicotinic acid, apho sikhokelo iye yachazwa ngentla ichiza ziluncedo nokuthintela kunye nokunyanga izifo ezininzi. Yena uthatha inxaxheba kwiinkqubo pathways kunye oxidative ukuba kwenzeka emzimbeni, kuquka inkqubo ukutya.