Huntington kaThixo

Huntington kukuba isifo ilifa ezinqabileyo. Ityhileke ngayo malunga omnye umntu ishumi lamawaka. Huntington kaThixo evusa kuphazamiseka phambili kwinkqubo luvo. Ukungaphumeleli inkulu ibanjiwe kubini, ebekwe nzulu kweziyobisi ebuchotsheni, izihloko iiseli. Eliqokobe kunye caudate isiqalo. Le mimandla inxaxheba ekumiseleni izenzo ngokungenasizathu kwinqanaba ienjini. Ebangela isifo Huntington kaThixo ayifani ncam, kodwa izazinzulu kuqhubeka ukusebenza kulo mba.

Iimpawu izifo kwenzeka, ngokuqhelekileyo phakathi kweminyaka engamashumi amathathu anesihlanu ukuya amahlanu. Ezi mpawu ziphambili eziyelelene Huntington ziquka:

- ukuphazamiseka intshukumo;

- ukwehla okuqhubekayo umsebenzi yengqondo ukuya ku sengqondo esixhalabisayo.

Ukongeza, ukuba Inokwenzeka, kunye nezinye iimpawu ezinxulumene ukuphazamiseka kwenkqubo luvo.

Uninzi lwezigulane (malunga 90%) sifo Huntington kaThixo luphawulwa iintshukumo ngokuzenzekelayo spasmodic (chorea). Oku kaninzi uphawu lokuqala.

iingcali nezinye izifo intshukumo ziquka ngqongqo, okanye utshintsho kwezihlunu, ubunzima kunye neentshukumo ngokuzithandela kunye neengxaki postural indlela ecace ngayo yokubiza amagama (dysarthria), ubunzima yokuginya (dysphagia), yaye bazive yezithuthi indalo bahlupheke iliso.

Progressive nokwehla kancinane kumsebenzi yengqondo okuhambisana Huntington kaThixo, ngaba kuthi kunye nophuhliso ukuphazamiseka kwengqondo. Izigulane, ingakumbi, akakwazi ingqalelo, balahlekelwe ixesha elide elifutshane inkumbulo, ukukwazi ukuqonda ukuba bafumane izisombululo kusengqiqweni iingxaki. Ngokuba ezinye izigulane, luphawulwa nochuku, ukutshintsha kwindlela yokuziphatha ngokwesini, ndlongo, ukungakhathali, ukugula ngengqondo, ukudandatheka.

Ukuba kukho iimpawu ngezifo ngenxa uxilongo oluchanileyo kufuneka engqina ubukho syndrome phakathi imbali yosapho izalamane. Ukusebenzisa uhlolisiso e-nervous system xa abathwali sofuzo engaqhelekanga ivumela ukumisela utshintsho okungephi isantya, ulawulo lweentshukumo kunye abasabela elide ngaphambi kwexesha xa sigulo abe libizwe.

Uhlalutyo Laboratory wegazi usebenzisa iisampulu DNA kusetyenziswa lokufumana okuthile kumaqela athile. Ezi ziquka:

- izigulana - zofuzo zenethiwekhi;

- izigulane ubungqina izifo;

- iintsana esizalweni.

Nakuba kunjalo, kufanele kuqatshelwe ukuba kuphando lwemfuzo enokukucaphukisa a xi namandla ngokwaneleyo kwaye ibeke ikhondo ngakumbi yokukhulelwa.

Kule nkqubo zokufumanis efunekayo kukuba ngaphandle nezinye izinto ezibangela zophuhliso sifo. Ezi ziquka, ingakumbi, bafumana didi ezithile zemithi, ukufa kwamalungu omzimba, zokuhlukunyezwa ixesha elide utywala.

Namhlanje esi sifo ayikho zifo. Nakuba kunjalo, isicelo amanyathelo zonyango ejolise iimpawu, ukunciphisa namandla, kwakunye nokubonelela lokhathalelo lwengqondo kwizigulane.

Phakathi iziyobisi ukunciphisa ubungqongqo iimpawu, phenothiazines ezisetyenzisiweyo. Ziyayilawula chorea. Unyango enyulwe ngokwaneleyo ngenyameko, ngokungqinelana iinkalo isigulane ukuze uphephe iziphumo ebezingalindelekanga. Ukugcina ulawulo ngqongqo kwe izihlunu ziyakwazi kwamanye amachiza - agonists dopamine. Noko ke, ukwenza ibonisa ukuba le meko, ukuba ngaphantsi kwe izifo Parkinson ngayo ngempumelelo.

Ukuze ukukhathazeka, badandatheke, ucaphuka kunye nezinye izifo yezengqondo-iimvakalelo, izigulane ukuyifundisa emiselweyo.