Lupus anticoagulant - uyingozi

On ekunqandeni igazi kuchaphazeleka ezininzi parameters, apho kumiselwa uhlalutyo kwemichiza igazi kunye nokufunda coagulation, kodwa kunjalo kuyimfuneko ukukhumbula ukuba zonke izalathi kufuneka ukuba nazo zizivandlakanye ugqirha kwaye axhomekeke kulo mzekelo kuphela ukuvavanya Isalathisi enye, kwaye kwiziphumo isifundo ezibanzi. Kwezinye iimeko, coagulation igazi kunye nenkqubo anticoagulation yovavanyo kufuneka enze neemvavanyo ngumzimba, umzekelo, ukuba unikele ngegazi ukuze antibodies cardiolipin kunye lupus anticoagulant.

Yintoni lupus anticoagulant nokubaluleka kwayo emzimbeni womntu

Phantsi kweemeko eziqhelekileyo, coagulation igazi kunye neenkqubo anticoagulation zilingana, - flowability yegazi igcinwe njalo kwi imithambo yegazi engekho umonakalo thrombus benazo zokonzakala amanxeba nayiphi na indawo. Ngako oko, xa lwee- kwezinto ezithile kwi-serum egazini kufuneka kwandiswa ukuze abuyekeze kunye nezinye - kuphela kule meko ke thrombosis isilumkiso kunokwenzeka. Kodwa ke umzimba womntu imbuyekezo ezi nguqulelo kuphela umda ethile, emva koko uza kukho ixesha xa nokuba awayekade thrombosis na ukuba imzisele ukopha - izinto abanoxanduva ekunqandeni igazi, nje musa ukuhlala kwi serum. Kuyinto into ezinokubangela iingxaki coagulation ziquka lupus anticoagulant - into ekhethekileyo protein endalo, nto leyo iba immunoglobulin yabantu.

Iveliswe ezi zithinteli kwakunye antibodies cardiolipin kunye phospholipids ngokubanzi, xa iiseli zamajoni omzimba, yaye inkoliso yezi zinto egazini kubonakele ku iintlobo zezifo sokuhlasela. Kodwa ke ingxaki lilele yokuba lupus anticoagulant HIV ngexesha lokukhulelwa, lube unobangela iingxaki ezahlukeneyo kwicala umfazi omithiyo, kwaye ukusuka olungekazalwa. Kufuneka kuqondwe ukuba ekufumanekeni yelupus anticoagulant kungekho antibodies DNA ezahlukeneyo nomonde, phospholipids, cardiolipin uthethe kuphela yethuba ezi ziphumo bezingalindelekanga kunye nemfuneko kweliso unyango rhoqo malunga nesigulane eso.

Kumele kukhunjulwe ukuba ukuvuselelwa anticoagulant lupus, nto leyo eqhelekileyo kunye na serum igazi nemiqulu 0.8 ukuya 1.2 iiyunithi engenasizathu, ayikho ngokwaneleyo sisalathisi oluthembekileyo. Ngoko ke, ekufumanekeni kwamanqanaba ephakamileyo okanye isifundo japan athandabuzekayo kuyimfuneko ukuba enze ezintsonkothileyo coagulation kufuneka luchaze D-dimer, ixesha coagulation (APTT) kwaye nebar inani elikhulu lwezalathisi le ncwadi ethi - exhomekeke kule ukuqikelela, kunye amaqhinga unyango umntu ogulayo kunokwenzeka.

Lupus anticoagulant - apho kudingeka uphando

Ekhawulezileyo uvavanyo lwegazi lupus anticoagulant kuya kufuneka nje kuphela abasetyhini abakhulelweyo. Olu hlahlelo isebenza kwaye yabelwa izigulane phambi kweminyaka engama-40 wabonakala emithanjeni kunye thrombosis lwemithambo nayiphi na indawo, thromboembolism, ukopha ngesiquphe okanye sistroke kobuchopho ngaphandle phambi ezo zifo apho unokuba ukujikeleza ebuchotsheni (umfutho wegazi, Cardio atherosclerotic). Wabalasela amabhinqa aselula, abo ebomini babo baye amatyala ukufa ngesiquphe kosana olungekazalwa naliphi na ibakala ukukhulelwa xa kungekho izifo yemfuza nosuleleko ezingekazalwa. Kuphela esweni rhoqo yemida coagulation, yivala lupus, antibodies phospholipids kunye cardiolipin uyakwazi ukukhetha i unyango olusebenzayo - kuphela Kule meko kungenzeka ukuba ukuthintela ukunwenwa ukuphazamiseka ukopha.