Epinephrine: Yintoni na? Epinephrine: imiyalelo esetyenziswa kunye nengxelo

Epinephrine - ntoni na? Le nto ke iya kuthi kwinqaku langoku. Uza kufunda iinjongo apho iziyobisi bathi isetyenziswa, ingaba unazo Izimo kunye neziphumo ebezingalindelekanga.

iipropati chemical

Epinephrine - ntoni na? Kutheni sifuna le nto? Ngokutsho kweengcali, le yenye yezona neurotransmitter ibalulekileyo yenziweyo adrenal. Elinye igama le sakhi adrenaline.

Afana iyeza mbuzo inxulumene catecholamines. Ngoko ke, lo epinephrine na epinephrine synthetic.

Xa imeko eziqhelekileyo emzimbeni, le ezimbaxa ifumaneka kwiindawo ezininzi kunye namalaphu. It iveliswa inyama chromaffin.

Epinephrine, imiyalelo ukusetyenziswa oboniswe ngezantsi, onesiphumo receptors alpha-beta-adrenergic, kwaye kananjalo iyazingenela excitation le luvo novelwano.

Phantsi uxinezeleko, ingqiqo ingozi, ixhala, uloyiko, ukutsha kunye ukwenzakala ezahlukeneyo zoqhaphelo epinephrine emzimbeni inyuswe kakhulu. Kuthatha inxaxheba zonke iintlobo ukutya, kwaye ichaphazela iswekile yegazi kunye izihlunu umzimba, kwandisa gluconeogenesis, glycogenolysis, catabolism protein kunye namanqatha inkqubo nokwaphuka, ukuze kuthintelwe glycogen amagama in kwezihlunu zesibindi kwizihlunu.

release Form

Epinephrine: ntoni na nokuba yintoni ifomu iveliswa? Kukho iintlobo ezahlukeneyo ukukhululwa epinephrine. Oku kuthengiswa ngokohlobo zamathontsana okanye granules ngamayeza lolawulo ngomlomo, kwakunye izisombululo injectable kunye nokusetyenziswa mlonyeni. Ukongeza, le nto iveliswa ngokohlobo tincture okanye iziyobisi-kweziyobisi umgubo.

iipropati kwemithi

Ziintoni iimpawu epinephrine? Yintoni na, sasinixelele ngasentla. Ngokutsho iingcali, esi sixhobo uba hyperglycemic, unesifo, vasoconstrictor, bronholiticheskoem kunye nesenzo antiallergic.

adrenaline Synthetic kwinqanaba zeselula, iyazingenela cyclase enzyme adenylate kwandisa yoxinaniso kweminquba kunye calcium ion. Le izinto kwandisa uxinzelelo lwegazi constricts iimpahla enyama yangaphakathi, ulusu, inwebu yangaphakathi, izihlunu skeletal, kwaye kwakhona iye iimpahla ingqondo.

imali iimpawu

hydrochloride Epinephrine buyasikhulula izihlunu amathumbu, kunye bronchi. Ukongeza, oko kukhokelela ekwandeni umfundi.

Sebenzisa amayeza ngale nto kwandisa ibango oksijini intliziyo kwaye ithintela uphuhliso bronchioles nokudumba. Kwakhona, eli chiza kunciphisa izinga ukufunxeka iintlungu zasekuhlaleni, kunciphisa ubungozi kunye kwandisa ixesha eliqhubekekayo le mali ilungiselelwe Ukubulawa zasekuhlaleni.

ubungqina

Yintoni ukusebenzisa epinephrine? Ukusetyenziswa kwale ndlela iboniswe ukususa abakufutshane uhlobo nezidlo ezithe savela ngenxa ukutofelwa igazi, ukuvuleleka kweziyobisi ekusebenziseni iimveliso ezahlukeneyo, impovane okanye emva kokuba ukuqaliswa naziphi na izakhi.

Kwakhona, iyeza lisetyenziswa kwezi meko zilandelayo:

• cupping isifuba inyumoniya;
• ukuze asystole;
• ngokuvuselela iintlungu bendawo;
• kunye bronchospasm, elavela ngexesha Ukubulawa;
• xa hypotension akazange enyangekayo ukusebenzisa fluid replacement;
• kuba unyango lwe hypoglycemia kubefundisi insulin libanda;
• ukunqanda ukopha;
• kunye open-engile neglaucoma ukuze kwandiswe umfundi;
• ngayo unyango priapism.

Izimo

iingcali Epinephrine hydrochloride musa yaleza ukusebenzisa kwi:

• hypersensitivity, uxinzelelo oluphezulu lwegazi;
• nokukhulelwa;
• cardiomyopathy hypertrophic ;
• isifo sentliziyo kobuchopho kwaye tachyarrhythmia;
• abantu ventricular fibrillation;
• pheochromocytoma;
• ibele.

Kufuneka ilunyukelwe kakhulu ukuba isigulane unalo ezimbi zilandelayo kunye nemiqathango:

• hypercapnia;
• ventricular arrhythmias, fibrillation atrial , kunye hypoxia;
• BP pulmonary;
• ukopha, kubuhlungu, okanye kukothuka cardiogenic ;
• thyrotoxicosis;
• izifo yegazi occlusive;
• isifo Raynaud kaThixo ;
• yamafutha okanye isifo Buerger kaThixo ;
• endarteritis abaneswekile;
• kwemithambo yegazi yobuchopho;
• isifo Parkinson kaThixo;
• seswekile kunye glaucoma engile-ukuvalwa;
• ukwanda umsebenzi kuhluthwe izinto;
• hypertrophy ngayo le ndlala wendlala;
• abantu lactic metabolic;
• emva kokonzakala ebandayo;
• iqhosha post-engabalulekanga;
• abantwana kunye nezigulane abadala.

Epinephrine: imiyalelo yokusebenzisa

Amaninzi iimveliso ngokusekelwe epinephrine ezilawulwa intramuscularly okanye kwesikhumba. Kwakhona arhente drip iphethwe yegazi.

Cupping inyumoniya isifuba medicament ilawulwa kwesikhumba xa isixa 0.3-0.5 mg.

Ukuba abambe angeva zintlungu, ichiza emiselweyo 5 mg / ml.

Ukumisa epinephrine ukopha kusetyenziswa ngokwemixholo. Lisetyenziswa kwi swab ndawo eyonakeleyo zifakwe isisombululo.

Ukuba asystole ubonisa izitofu intracardiac, kwaye ngexesha yokurhaxwa - efakwa.

Vula therapy angle neglaucoma ikhutshwa phandle instillation ka 2.1% isisombululo emehlweni ezichaphazelekayo 1 drop kabini ngemini.

imiphumela emibi

Ngokutsho oogqirha, epinephrine kungabangela:

• sifuba angina, tachycardia, iyangongoza, bradycardia, ukuncipha okanye ukwanda uxinzelelo lwegazi;
• arrhythmia ventricular, iintlungu esifubeni, arrhythmia intliziyo;
• ixhala, lafa, isiyezi kunye nentloko ebuhlungu;
• ukudinwa, ukuziva ezibandayo okanye ubushushu, uvalo;
• sokulibala, ukuphazamiseka NA, zokurhwaqela kwezihlunu ezizenzekelayo, nokudideka njalo njalo.

analogs

Yintoni kuqwalaselwa endaweni indlela yethu? Epinephrine equlethwe imixube ezifana epinephrine tartrate, iadrenaline, epinephrine tartrate, iadrenaline tartrate, hydrochloride adrenaline - igutyana.

Kufuneka kuqatshelwe ukuba articaine, epinephrine ezingaqukwanga kwi "Septanesta" iadrenaline, "Alfakaina SP", "articaine INIBSA", "Artifrina", "Primakaina" iadrenaline, "articaine D-C", "Ubistezina", "Brilokaina -adrenalina "," artikaina DF "," Tsitokartina "," artikaina Perrelet "kunye adrenaline.

reviews

Ukuphonononga osisiqu uchaphazelekayo encinane kakhulu. Oku kungenxa yokuba eli yeza lisetyenziswa kuphela likaxakeka kwaye esibhedlele.

Ngokutsho kweengcali, epinephrine yinto into ebalulekile kaninzi kunceda ukusindisa ubomi umguli.