Sokugonya se-HIV kuya kunceda ukudala izilwa ezinkomeni

Iimazi zingadlala indima ebaluleke kakhulu kumlo ochasene ne-HIV. Kuthotho amalinge, abaphengululi bafumanisa ukuba iinkomo uyakwazi ukuphuhlisa ngokukhawuleza antibodies zentsholongwane, nto leyo enokusinceda ekuvelisweni isitofu sokugonya yokulwa nesi sifo buhlungu.

Izinga lomzimba

Umsebenzi owenziwa yi-US National Institutes of Health, lubonise ukuba iinkomo abanentsholongwane kunye nezakhi-HIV, baqala ukwenza izilwa eyaziwa ngokuba bNAb (ngokubanzi izilwa lwaze) ebopha kumphezulu iantigens evulekileyo kuphela. Emva kweentsuku 42 kuphela, izazinzulu ziye zafumanisa ukuba izilwa kwinkomo nga yokungenelela-20 ekhulwini strains uvavanyo lwe-HIV, kwaye kwiintsuku 381 inani lanyuka ukuya 96 ekhulwini.

"Ezi ziphumo bothuka ngokwenene thina, - utshilo uGqr Devin Soklt. - Bade nzima ukukukholelwa, ekubeni umzimba abantu ukuphuhlisa izilwa-buhlungu, sithetha iminyaka, kuthatha ezintathu ukuya kwezintlanu. Oku kubaluleke ngokwenene kuba umzimba wethu ayikwazi ngexesha elingephi ukumelana nalo msebenzi ubalulekileyo. Ngubani ababecinga ukuba inkomo iza kwenza igalelo elibonakalayo kumlo ochasene ne-HIV? ".

iimpawu ezizodwa amajoni omzimba iimazi

Iinkomo abakwazi Awunokosulelwa YINTSHOLONGWANE KAGAWULAYO ngendlela yemvelo, njengoko intsholongwane sokuba obeku- kwaye lujoliswe, ukuhlasela iiseli zabantu. Nakuba kunjalo, abaphandi baye banomdla ukwazi indlela umzimba amathokazi aya kusabela kuyo intsholongwane kuba amajoni omzimba yeenkomo inemisebenzi ezizodwa zifanele, ngokommiselo izazinzulu, Andinamali ukuba ukhuphe izilwa ezinamandla njengempendulo usulelo.

Abaphandi zenyuse nezakhi viral amathole 117 ukufunda impendulo eziphilayo. Nangona kunjalo, isantya impendulo amajoni omzimba zezilwanyana yahlaselwa ngabaphandi. Bona bathi, ngenxa inkqubo yokucola imazi ezaliswe iintsholongwane ukuba ukugaya utyani, amajoni omzimba yezilwanyana wamkela ukukwazi ukuvelisa ngokukhawuleza antibodies ukugcina ezi ntsholongwane phantsi kolawulo.

Kwiimeko ezinqabe kakhulu, abanye abantu abakwaziyo ukuvelisa ngokwendalo izilwa-buhlungu ezinjalo, kodwa ekubeni kuthatha ixesha elide emva kokosuleleka, intsholongwane ilawula lokuziguqula ukuwalungisa. Noko ke, iinkomo bNAb yavelisa kwisithuba kwiiveki ezimbalwa.

Nangexabiso lomsebenzi wophando entsha

"Iziphumo zethu badumileyo ngokuba imfuyo, kuyabonakala ukhupha izilwa bNAb kwixesha elifutshane ixesha. Ngokungafaniyo izilwa yabantu iinkomo kungenzeka ukuba iimpawu ezizodwa kwaye i uncedo immunogens esimbaxa HIV ", - wachaza UDennis R. Burton, awonisa isifundo.

Nangona esi siphumo kubalulekile, abaphandi zilumkisa ngelithi omzimba abakwazi ukusebenzisa ngqo ekulweni HIV ebantwini. Nangona kunjalo, oku kunokuba linyathelo elibalulekileyo ukuvelisa enye ehambelana kunye nenyama omzimba zabantu, nto leyo inokujikwa ibe sokugonya.