Levonorgestrel: yintoni na le hormone, yaye apho nguye onoxanduva umzimba?

Abantu abaninzi bayazibuza: levonorgestrel - yintoni na le hormone? Oku a progestagen eyenziweyo esiguqula endometrium kunciphisa ovulation ziyibuyisela kwezichumiso kweqanda walungisa. Ngapha koko, oku mucosal receptors yehle ubuntununtunu ifunyenwe. Kweli nqaku siza kujonga amalungiselelo equlethe ihomoni okuthiwa.

Pharmacology

Ichiza "Levonorgestrel" - na estrogen, onqanda ukusebenza madlozi ngenxa ukwandisa iipropati yencindi viscosity. Ichiza wenza apha ngaphakathi wesibeleko kwi ityhubhu Imibhobho, lo endometrium, ukuyondelelana kwendlela kwi yencindi, nto leyo hormone follicle-ushukumisa kunciphisa umsebenzi wayo.

Zokungenisa ebizwa amayeza ngenkuthalo wendele phecana zesisu, Bioindication ukuya kwi-100%. Egazini, iindawo kuyo ingqalelo ulwamkelo ubuninzi razovo 75 ml emva 60 - imizuzu 130. hormone kujongwa oko lisebenzisana plasma kunye globulin ndibopha nama-50%.

Lokugaya swi ophezu kwesibindi, ifomu passive metaboliks pharmacologically. Eyona isoenzyme iphambili yale hormone CYP3A4. Ixesha isiqingatha-ubomi ungatsala ukuya kutsho kwiiyure ezingama-30.

izakhiwo

Ukuphendula lo mbuzo, "Levonorgestrel - yintoni na le hormone?" kufuneka akhokelwe ingqeqesho igama elifanayo lechiza izindululo ugqirha khona. Izalathisi jikelele ixabiso umahluko ngokomyalelo 1.0 ml / min. / Kg (plasma). Hormone iyapheliswa ingakumbi ureter, inxalenye encinane liyasuswa esitulweni.

Xa unyango wendalo systemic ukuwa izalathisi ngesantya isibeleko ayikho ngaphezu kwama-20 mg yonke imihla, yaye emva kweminyaka emihlanu kuwa ukuya 11. Umlinganiselo yemveliso hormone yahluka kweziyi 14 ug / 24 hr. Ngaphezu kweenyanga 50-60.

Unyango intrauterine avunyelwe ukuba amabhinqa kunye unyango hormone ngokusebenzisana estrogen, progestin ke kuquka nokwakheka. Levonorgestrel - a implants hormone kwi-plasma engama-60 emva kokuba yolawulo. yoxinaniso obukhulu kuwo kubhalwe emva kweentsuku ezili-14 isicelo.

ubungqina

Ukusetyenziswa kweli chiza kunokwenzeka ngezakhi intrauterine, kwakunye kwezi meko zilandelayo:

• Ukuziqhelanisa menorrhagia Idiopathic.
• Long-term protection yokucwangcisa.
• Amanyathelo othintelo zokunciphisa endaweni ne estrogen.
• Emergency yokuthintela ukukhulelwa.

Le levonorgestrel ihomoni, ifuthe lwalo imihlaba ebanzi, ezi zinto zilandelayo ziya kusebenza kuphela emva kwisindululo kugqirha.

Sebenzisa nokuba umthamo

Ingqalelo ichiza owenziwe inaliti intrauterine - lesitofu lweHo- zesibeleko. Isetyenziswa iintsuku-4 emva kokuba neentlobano kwi imali mg 0.75 ukuya 1.5. nocwangciso lonxunguphalo iingcali bayacetyiswa ngamandla ukuba benze ngaphezu kanye qho emva kweenyanga ezintandathu.

Ukuphelisa le sexesheni, kuyimfuneko ukuba athobele idosi ekucetyiswa ngaphandle ukusetyenziswa-. Musa ukusebenzisa ingxelo kweziyobisi ngomlomo nje indlela yokucwangcisa osisigxina, njengoko oku kuphakamisa ukubonakala iziphumo ebezingalindelekanga kwaye kunciphisa ukusebenza beziyobisi. Kwimeko ukuyilwa igazi zesibeleko emva uthintelo olungxamisekileyo kuyacetyiswa kakhulu inkqubo luhlolo ngumbelekisi, nokunyhashwa exesheni ngeveki ngaphezu kwesinye kuyimfuneko ukucothise ukukhulelwa.

Kuphela emva kokubonisana kwaye baziswe ugqirha isigqibo kwiimeko eziqhelekileyo, oko ivumela inxaxheba beziyobisi ukuba inzalo abantwana ngexesha likaxakeka.

Njengoko kusetyenziswa hormone levonorgestrel?

ntoni emzimbeni usebenzisa njani hormone kuchaziwe, yaye yintoni ntoni ukunqanda imiphumela emibi? Ngoko ke umbuzo uvuka yi abaninzi. ukubambelela ngokungqongqo ngeengcebiso zeengcali, ukuhlonipha idosi ulandele imiyalelo - iqinisekisa ukusetyenziswa ngokukhuselekileyo ichiza.

Phambi ukusetyenziswa, kufuneka kudlule ukuhlolwa oko Navy ugqirha, kuquka namadlala mammary ngetshekhi, amalungu zangasese, ukwenza smear wesibeleko.

Re-Oluhlolo lwenziwa emva kweentsuku 30-40 emva lofakelo uwele, ngoko ngonyaka, yaye xa kukho presuppositions - rhoqo. Olu nyango intrauterine iyasebenza iminyaka-4 ukuya kwezi-5. ufakelo wayo kufuneka kuqhubana igqirha specialising kule intsimi okanye uno lwazi nge uhlobo kuqwalaselwa beziyobisi.

ubungozi

Abasetyhini iziyobisi kunye Progestogen, kunokwenzeka ukuba kwande thrombosis lwemithambo ngephanyazo ezibalulekileyo. Xa iimpawu ezinjalo imfuneko engxamisekileyo ukuthatha amanyathelo ngokukhawulezileyo isifo kwaye afumane unyango.

Emva kokuba ukurhoxiswa Navy lokuzala resuscitated emva kweenyanga ezintandathu isiqingatha abafazi isicelo emva kweenyanga ezili-12 - ngaphezu kwe-96 ekhulwini. orientation ukukhulelwa ngaphantsi olusebenzayo izigulana ukutyeba.

Izimo

Ezibuza "Levonorgestrel - yintoni na le hormone?" kufuneka siqwalasele zonke Izimo. Phakathi kwabo:

• Beyond (ehleliyo) onovakalelo, tromboflebitnye ukwakheka.
• Thromboembolism, utshintsho yegazi.
• isifo Cerebrovascular orientation, ukukhulelwa.
• Malunga nokudla: senyongo (kuquka imbali), iingxaki zophendlo lwezifo imveliso ibile okanye isibindi, zisanyisa.
• ukuvuthwa ngokwesondo.
• Ngaphezu koko, ngokuba IUD - esiludumbo sisifo usuleleko enzala okanye ukudumba inxaxheba isinqe, nokubanjwa kwezinto Kukudandatheka endometritis, etsolo isifo zesibindi.
• ukungenelela yokubolisa abortifacient kwithuba leenyanga ezintathu yokugqibela, dysplastic inguqu zesibeleko wesibeleko ngezifo kwi ezophayo efanayo imvelaphi ongaziwayo, umhlaza.
• Yiza okanye mgaqweni iziphene agqwetha fibroids.
• Progestagenoz (ithumba, kubandakanywa izilonda ibele ngumhlaza).

izithintelo

Umba osisithintelo Kudla ochaphazelekayo ukwenzela ukuba angenelele kwezonyango kungena isibeleko, le ndawo ukuba ibe ukuba unazo ezi mpawu zilandelayo okanye izifo ezondeleyo:

• enentloko engapheliyo, a migraine okuqhelekileyo yobulali nge ukungaboni, ezinye iimpawu, swi nga ithuba kwemithambo;
• ecacileyo ulwalathiso umfutho wegazi, nenyongo, iinkqubo entshabalalo entsonkothileyo kwinkqubo yokujikeleza kwegazi, kuquka isifo sentliziyo kunye nesifo;
• iswekile osegazini.

Kufuneka kwaoko andibhekisanga kwi Ukuphelisa Navy ngexesha lokusekwa okanye ubukho nayiphi na kwezi States.

Ukukhulelwa ne zisanyisa ixesha

Ngaphandle kokuba levonorgestrel - yincindi nemazi, ukusetyenziswa kwayo ayamkelekanga ngexesha lokukhulelwa. Ukuba yeza, bubulumko nokuphelisa kwenkqubo ngenxa yokuba nayiphi kukhulelwa intrauterine kwandisa umngcipheko nokubeleka ngaphambi kunye kwezisu. Ndiqhuba unina inkqubo yokuqonda okanye Susa maxa wambi kubangela isisu kwenzeka ngokuzenzekelayo. It ufuna ingcebiso ingcali ukuba nokwenzeka lokuyeka ngumntu zokukhulelwa xa kwimeko nakwenzeka gesi oluchanekileyo ukukhulelwa.

Xa kunzima ukususa inkqubo intrauterine kunye nomnqweno engxamisekileyo ukugcina ukukhulelwa isigulane kufuneka bazazi iziphumo kunokwenzeka neengozi ukuba usana ngenxa ekuzalweni kwexesha. Kwiimeko ezinjalo, kufuneka uqiniseke ukuba esweni ngokusondeleyo nokukhulelwa. Phambi kokuba isigulane kufuneka ungenise ulwazi kwangoko kufuneka bazise ngazo zonke iimpawu, nto leyo eya kunceda ukucebisa nkqubo ingxaki.

zisanyisa

Xa uncancisa kwaye usebenzise "Levonorgestrel" kwisinye seshumi isiyobisi engena usana umzimba. Uncancisa ngaphakathi uthintelo olungxamisekileyo kufuneka ayekiswe kwiintsuku 1.5.

e esithathwa Kucetyiswa ukuba inkqubo enyangayo ezifakwe Esibelekweni, njengaye nawuphi na ndlela ithile yokuthintela Progestogen-kuphela, oko luphawu ukuba ukusetyenziswa kwiinyanga ezinesiqingatha emva kokuzalwa abakuwo ekukhuleni kunye nophuhliso umntwana, ngoko, ichiza ekujoliswe kulo akunakufane kwenzeke ukuba kube yingozi kwimveku .

iimpawu ezingalunganga

Abuyele umbuzo "Levonorgestrel" - oko kukuthi, "makhe sijonge iziphumo ebezingalindelekanga ezinokubakhona kunye Izimo beziyobisi Baya ezinokwenzeka kwiinkqubo ezahlukeneyo apha emzimbeni kwaye ezi mpawu zilandelayo :.

1. Ukususela luvo: ukudinwa, ukudakumba, intloko ebuhlungu, zokulwa nale ngxaki.
2. Git. Ukugabha, inkinga, amahlaba, ukuqumba.
3. amalungu Genito-womchamo. Ukopha, ngokwahlukana, iintlungu, candidiasis, amathuba ukubunjwa yamathumba okubulalayo ebubonisayo.
4. irhashalala, ngokubonakala nangokhwekhwe, ukurhawuzelela, irhashalala, induna.
5. Okunye: ukudumba, amalungu abe buhlungu, yokugaleleka ngamandla, nokudumba.

Kwiimeko ezinqabe ukuxhuzula yexhuzula, amahlaba kunye niphele.

Kolimo namanye amachiza

Ukufunda "Levonorgestrel" (olunjani hormone), kuyimfuneko ukukhankanya amathuba indibanisela kunye nezinye iziyobisi kunye neziyobisi organic. Kwimeko iyeza umbuzo inducers of cytochrome isoenzymes P450 kunganciphisa ukusebenza ngenxa yokwanda iinkqubo metabolic.

Amachiza ilandelayo ukunciphisa ifuthe "Levonorgestrel":

• barbiturates Group, "Tretinoin", "carbamazepine" ezaqanjwa eziqulathe Wort St. bakaYohane komponatsiyu yayo.
• Kunciphisa ukusebenza anticoagulants, hypoglycemic, iziyobisi anticonvulsant.
• "Levonorgestrel" kwandisa umthamo glucocorticoids egazini, kwaye inawo amandla ukuphazamisa ukutya.
• Ngenxa kwezithandani ngesini steroid recirculation, ngenxa ngokuhlanganisa izilwanyana isisu, ukwanda ukopha sexesheni kunokwenzeka xa esimbaxa isicelo iziyobisi ezithile.

Umntu akakwazi kodwa ukongeza, ukuthetha malunga nendlela yokusebenzisa "Levonorgestrel 'ukuba eli yeza ibangela ukwanda neziphumo ebezingalindelekanga zezinye amayeza, i ebubuvuvu loo ayikho. Kwimeko libanda, zifuna unyango nomqondiso.